ES2159843T3 - Derivados de 5,11-dihidrodibenzo(b,e)(1,4)oxazepina y composiciones medicamentosas que los contienen. - Google Patents

Derivados de 5,11-dihidrodibenzo(b,e)(1,4)oxazepina y composiciones medicamentosas que los contienen.

Info

Publication number
ES2159843T3
ES2159843T3 ES97905478T ES97905478T ES2159843T3 ES 2159843 T3 ES2159843 T3 ES 2159843T3 ES 97905478 T ES97905478 T ES 97905478T ES 97905478 T ES97905478 T ES 97905478T ES 2159843 T3 ES2159843 T3 ES 2159843T3
Authority
ES
Spain
Prior art keywords
derivatives
compositions containing
eüä1
dihydrodibenzo
oxazepine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97905478T
Other languages
English (en)
Inventor
Yuji Tanaka
Keiji Misumi
Yoshinari Kawakami
Masahiko Moriguchi
Kazuyoshi Takahashi
Hiroki Okamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Application granted granted Critical
Publication of ES2159843T3 publication Critical patent/ES2159843T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

DERIVADOS DE 5,11 - DIHIDRODIBENZ [B,E] [1,4]OXAZEPINA TALES COMO (R - (+) - 5,11 - DIHIDRO - 5 - [1 - (4 - METOXI - FENETIL) - 2 - PIRROLIDINILMETIL]DIBENZ[B,E][1,4]OXAZEPINA O (R) - (+) 5,11 - DIHIDRO - 5 - [1 - (4 - FLUOROFENETIL) - 2 PIRROLIDINILMETIL]DIBENZ[B,E][1,4]OXAZEPINA; ESTEREOISOMEROS DE LOS MISMOS, SALES FARMACEUTICAMENTE ACEPTABLES DE LOS MISMOS E HIDRATOS DE LOS MISMOS; Y COMPOSICIONES DROGAS QUE LOS CONTIENEN. ESTOS COMPUESTOS EXHIBEN UNA EXCELENTE ACTIVIDAD EN LA MEJORA DE LA FUNCION MOTORA DEL TRACTO DIGESTIVO SIN EFECTOS ADVERSOS.
ES97905478T 1996-03-11 1997-03-11 Derivados de 5,11-dihidrodibenzo(b,e)(1,4)oxazepina y composiciones medicamentosas que los contienen. Expired - Lifetime ES2159843T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8310496 1996-03-11

Publications (1)

Publication Number Publication Date
ES2159843T3 true ES2159843T3 (es) 2001-10-16

Family

ID=13792896

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97905478T Expired - Lifetime ES2159843T3 (es) 1996-03-11 1997-03-11 Derivados de 5,11-dihidrodibenzo(b,e)(1,4)oxazepina y composiciones medicamentosas que los contienen.

Country Status (16)

Country Link
US (2) US6127361A (es)
EP (1) EP0889043B1 (es)
JP (1) JP3127469B2 (es)
KR (1) KR100344331B1 (es)
CN (1) CN1085209C (es)
AT (1) ATE204871T1 (es)
AU (1) AU704521B2 (es)
BR (1) BR9707962A (es)
CA (1) CA2261271C (es)
DE (1) DE69706406T2 (es)
ES (1) ES2159843T3 (es)
NO (1) NO310976B1 (es)
PT (1) PT889043E (es)
TW (1) TW479057B (es)
WO (1) WO1997033885A1 (es)
ZA (1) ZA972038B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999012925A1 (en) * 1997-09-10 1999-03-18 Ajinomoto Co., Inc. 5,11-DIHYDRODIBENZ[b,e][1,4]OXAZEPINE DERIVATIVES AND MEDICINAL COMPOSITION CONTAINING THE SAME
WO2000040570A1 (en) * 1999-01-08 2000-07-13 Ajinomoto Co., Inc. Oxazepine derivatives and drugs containing the same
WO2001017980A1 (en) * 1999-09-03 2001-03-15 Ajinomoto Co., Inc. Novel processes for preparing oxazepine derivatives
AU2001217359A1 (en) * 2000-12-11 2002-06-24 Ajinomoto Co., Inc. Novel crystals of oxazepine derivatives and process for the production thereof
JPWO2002096891A1 (ja) * 2001-05-30 2004-09-09 味の素株式会社 ジヒドロジアリールオキサゼピン誘導体及び該誘導体を含有する医薬組成物
JP2005343791A (ja) * 2002-05-31 2005-12-15 Ajinomoto Co Inc 消化管疾患を治療するための医薬組成物
JP2005343790A (ja) * 2002-05-31 2005-12-15 Ajinomoto Co Inc カルシウムチャネル拮抗薬を含有する医薬組成物
CN104016937B (zh) * 2014-05-09 2016-12-07 中科院广州化学有限公司 一种n-芳基氧氮杂卓酮类化合物及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8912303D0 (en) * 1989-05-27 1989-07-12 Pfizer Ltd Therapeutic agents
CA2118688A1 (en) * 1991-11-05 1993-05-13 Timothy J. Hagen Substituted dibenzoxazepine compounds, pharmaceutical compositions and methods of use
US20020183271A1 (en) * 2000-12-07 2002-12-05 Sunil Chada Methods of treatment involving human MDA-7

Also Published As

Publication number Publication date
EP0889043A4 (en) 1999-07-21
NO310976B1 (no) 2001-09-24
DE69706406D1 (de) 2001-10-04
ATE204871T1 (de) 2001-09-15
PT889043E (pt) 2002-02-28
US6127361A (en) 2000-10-03
AU2233597A (en) 1997-10-01
NO984162D0 (no) 1998-09-10
EP0889043A1 (en) 1999-01-07
EP0889043B1 (en) 2001-08-29
TW479057B (en) 2002-03-11
AU704521B2 (en) 1999-04-22
KR100344331B1 (ko) 2002-12-05
DE69706406T2 (de) 2002-04-18
CA2261271C (en) 2003-09-16
WO1997033885A1 (en) 1997-09-18
CA2261271A1 (en) 1997-09-18
ZA972038B (en) 1997-09-17
KR19990087655A (ko) 1999-12-27
US6436922B1 (en) 2002-08-20
CN1213371A (zh) 1999-04-07
CN1085209C (zh) 2002-05-22
NO984162L (no) 1998-11-05
BR9707962A (pt) 1999-07-27
JP3127469B2 (ja) 2001-01-22

Similar Documents

Publication Publication Date Title
ES2138691T3 (es) Procedimiento para la obtencion de derivados de n-acil-5-fluorocitidina.
FI980341A0 (fi) 2-oksi-indolijohdannaisia
NO921835L (no) Fremgangsmaate for fremstilling av amidinofenylalaninderivat samt anvendelse derav
ES2148254T3 (es) Peptidos antimicrobianos ciclicos y preparacion de los mismos.
TR199801268T2 (xx) Ta�ikinin antagonistleri olarak 3-Azetidinilalkilpiperidinler veya pirolidinler.
ATE259823T1 (de) Tricyclische erythromycinderivate
NO306116B1 (no) Ny benzotiadiazinforbindelse og farmasöytiske sammensetninger
ES2159843T3 (es) Derivados de 5,11-dihidrodibenzo(b,e)(1,4)oxazepina y composiciones medicamentosas que los contienen.
KR960006915A (ko) 췌장염의 치료 조성물
KR920002151A (ko) 15-케토-프로스타글란딘 화합물에 의한 염증성 질환 치료
ES2111871T3 (es) Nuevos derivados de aminoacidos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
EP1073447A4 (en) N1-MODIFIED GLYCOPEPTIDES
PL344696A1 (en) Hyperforin derivatives, the use thereof and formulations containing them
PT922054E (pt) Derivados anti-coagulantes de aldeido de peptidil-arginina
TW330933B (en) Furanoeremophilane and eremophilanolide sesquiterpenes for treatment of diabetes
ES2173586T3 (es) Derivados de ciclohexandiol.
ES2164168T3 (es) Antagonistas de receptores de fibrinogeno que tienen residuos de beta-aminoacido sustituidos y composiciones farmaceuticas que comprenden los mismos.
ES2162986T3 (es) Derivados de mercapto-alcanoil-dipeptidos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
BR9815448A (pt) Derivados de imino-aza-antraciclinona para o tratamento de amiloidose
ES2104295T3 (es) Derivados ciclopeptidicos de la angiopeptina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
KR920003972A (ko) 프로스타시클린 화합물을 이용한 백내장 치료
AU567498B2 (en) 5-phenyl-1h-2,3-dihydro-1,4-benzodiazepine derivatives.
KR970702869A (ko) 항종양성 인돌로피롤로카르바졸 유도체(antitumor indolopyprolocarbazole derivative)
FI853506A0 (fi) Nya antibioter, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska kompositioner.
TW337521B (en) Non-ulcerogenic analgesic/anti-inflammatory cloixin derivative

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 889043

Country of ref document: ES