ES2162081T3 - Aparato y procedimiento para el mantenimiento y crecimiento de celulas biologicas. - Google Patents

Aparato y procedimiento para el mantenimiento y crecimiento de celulas biologicas.

Info

Publication number
ES2162081T3
ES2162081T3 ES96921439T ES96921439T ES2162081T3 ES 2162081 T3 ES2162081 T3 ES 2162081T3 ES 96921439 T ES96921439 T ES 96921439T ES 96921439 T ES96921439 T ES 96921439T ES 2162081 T3 ES2162081 T3 ES 2162081T3
Authority
ES
Spain
Prior art keywords
cassette
cells
cell growth
instrument
portable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96921439T
Other languages
English (en)
Spanish (es)
Inventor
R Douglas Armstrong
James Maluta
David W Roecker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vericel Corp
Original Assignee
Aastrom Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aastrom Biosciences Inc filed Critical Aastrom Biosciences Inc
Application granted granted Critical
Publication of ES2162081T3 publication Critical patent/ES2162081T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/54—Constructional details, e.g. recesses, hinges hand portable
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/42—Integrated assemblies, e.g. cassettes or cartridges
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Computer Hardware Design (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ES96921439T 1995-06-07 1996-06-07 Aparato y procedimiento para el mantenimiento y crecimiento de celulas biologicas. Expired - Lifetime ES2162081T3 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US48351695A 1995-06-07 1995-06-07
US48351795A 1995-06-07 1995-06-07
US48351895A 1995-06-07 1995-06-07
US48351995A 1995-06-07 1995-06-07
US48352095A 1995-06-07 1995-06-07
PCT/US1996/009770 WO1996040858A1 (en) 1995-06-07 1996-06-07 Apparatus and method for maintaining and growing biological cells

Publications (1)

Publication Number Publication Date
ES2162081T3 true ES2162081T3 (es) 2001-12-16

Family

ID=27541734

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96921439T Expired - Lifetime ES2162081T3 (es) 1995-06-07 1996-06-07 Aparato y procedimiento para el mantenimiento y crecimiento de celulas biologicas.

Country Status (7)

Country Link
EP (1) EP0832182B1 (2)
JP (1) JP3880622B2 (2)
AT (1) ATE204322T1 (2)
CA (1) CA2223525C (2)
DE (1) DE69614535T2 (2)
ES (1) ES2162081T3 (2)
WO (1) WO1996040858A1 (2)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010086465A1 (es) 2009-01-30 2010-08-05 Emilio Mateu Sentamans Método y equipo modular para el procesamiento y almacenamiento de cultivos celulares

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6825169B1 (en) 1991-10-22 2004-11-30 Trustees Of Tufts College Inhibitors of dipeptidyl-aminopeptidase type IV
US5965532A (en) * 1996-06-28 1999-10-12 Trustees Of Tufts College Multivalent compounds for crosslinking receptors and uses thereof
US6100234A (en) 1997-05-07 2000-08-08 Tufts University Treatment of HIV
US6040145A (en) 1997-05-07 2000-03-21 Tufts University Potentiation of the immune response
CA2304206A1 (en) 1997-09-29 1999-04-08 Point Therapeutics, Inc. Stimulation of hematopoietic cells in vitro
CA2331122A1 (en) 1998-05-04 1999-11-11 Point Therapeutics, Inc. Hematopoietic stimulation
AU765370B2 (en) 1998-06-05 2003-09-18 Point Therapeutics, Inc. Cyclic boroproline compounds
US6890904B1 (en) 1999-05-25 2005-05-10 Point Therapeutics, Inc. Anti-tumor agents
FR2794130B1 (fr) * 1999-05-26 2003-01-03 Bertin Technologies Sa Procede et dispositif de culture de cellules a applications multiples
DE60043640D1 (de) * 1999-10-11 2010-02-25 Dsm Ip Assets Bv Kontinuierliche Fermentation
WO2003087292A2 (en) * 2002-04-08 2003-10-23 Millenium Biologix Inc. Automated tissue engineering system
JP4751566B2 (ja) * 2002-04-09 2011-08-17 オリンパス株式会社 細胞培養システム、培養細胞照合装置および細胞培養装置
JP2004073187A (ja) * 2002-06-18 2004-03-11 Olympus Corp 培養関連容器管理方法および培養関連容器
WO2005068608A1 (ja) * 2004-01-14 2005-07-28 Daikin Industries, Ltd. 温度制御装置
GB0603965D0 (en) 2006-02-28 2006-04-05 Centeo Biosciences Ltd Incubator apparatus and method
KR100946643B1 (ko) * 2007-11-30 2010-03-09 코아스템(주) 세포배양장치 및 이를 구비한 대용량 자동화 세포배양기
KR100932861B1 (ko) * 2007-11-30 2009-12-21 코아스템(주) 세포배양플라스크
DE102009029305A1 (de) 2009-09-09 2011-03-10 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Analysegerät zur automatisierten Bestimmung einer Messgröße einer Flüssigkeitsprobe
WO2011130865A2 (en) * 2010-04-21 2011-10-27 Yves Larcher Automated cell culture system
JP5351823B2 (ja) * 2010-04-28 2013-11-27 株式会社日立ハイテクノロジーズ 自動分析装置
DE102012013267A1 (de) 2012-07-04 2014-01-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Substrateinrichtung, Konservierungsgerät und Verfahren zur Kryokonservierung einer biologischen Probe
JP6051730B2 (ja) 2012-09-24 2016-12-27 東洋製罐グループホールディングス株式会社 気泡除去方法、及び気泡除去装置
WO2016005971A1 (en) * 2014-07-06 2016-01-14 Fertilesafe Ltd Devices for culturing a biological sample in a culturing liquid
JP6339432B2 (ja) * 2014-07-16 2018-06-06 オリンパス株式会社 細胞観察情報処理システム、細胞観察情報処理方法、細胞観察情報処理プログラム
FR3053051B1 (fr) * 2016-06-24 2022-11-11 Cellprothera Cassette et automate de culture cellulaire
EP3505615A4 (en) * 2016-08-26 2020-05-27 IHI Corporation CELL CULTURE SYSTEM, CULTURE UNIT, AUTOMATIC CELL CULTURE DEVICE, AND TRANSPORT CELL CULTURE DEVICE
US10406252B2 (en) 2017-01-19 2019-09-10 Curium Us Llc Systems and methods for autoclave cart loading and unloading system
CA3248436A1 (en) 2017-09-01 2025-02-21 Lonza Walkersville, Inc. END-TO-END AUTOMATION OF CELL THERAPY
DE102018000561B4 (de) 2018-01-24 2019-11-07 Zellwerk Gmbh Mäander-Bioreaktor und Verfahren für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben
DE202018000370U1 (de) 2018-01-24 2018-04-12 Zellwerk Gmbh Mäander-Bioreaktor für die Isolierung und Vermehrung von Zellen aus Gewebeteilen von Tumoren, Metastasen und anderen Geweben
EP3556841A1 (en) * 2018-04-19 2019-10-23 Aglaris Ltd Disposable cartridge cooperating with a platform in a flexible system for handling and/or manipulating fluids
JP7396777B2 (ja) 2018-09-28 2023-12-12 オクタン バイオテック インコーポレーテッド 磁気分離
DE202018004857U1 (de) 2018-10-20 2019-01-14 Zellwerk Gmbh Mäander-Perfusions-Bioreaktor für die Differenzierung, Aktivierung, Stimulierung und Abtrennung von Zellen
KR20210108406A (ko) 2018-12-21 2021-09-02 론자 워커스빌 아이엔씨. 바이러스 벡터의 자동화된 생산
IL284214B2 (en) 2018-12-21 2025-03-01 Octane Biotech Inc Carousel for modular biologic production units
SG11202106652WA (en) 2018-12-28 2021-07-29 Octane Biotech Inc Cell culture and tissue engineering systems with controlled environmental zones
IL285288B2 (en) 2019-02-08 2026-04-01 Lonza Walkersville Inc Cell concentration methods and devices for use in automated bioreactors
JP7698625B2 (ja) * 2019-07-15 2025-06-25 ロンザ ウォーカーズヴィル，インコーポレーテッド 自動細胞工学システム用のプロセス制御システム
CN114729292A (zh) 2019-10-24 2022-07-08 奥克泰生物科技股份有限公司 具有经改进的细胞接触表面的细胞培养室
EP4058563A4 (en) 2019-11-11 2023-12-06 Lonza Walkersville, Inc. QUALITY CONTROL PROCEDURES FOR AUTOMATED CELL PROCESSING
EP3933479A1 (en) * 2020-07-03 2022-01-05 Leica Microsystems CMS GmbH Microscope for microscopic examination of a sample
WO2025202170A1 (en) * 2024-03-25 2025-10-02 The Automation Partnership (Cambridge) Limited Mobile bioprocessing module, bioprocessing unit and bioprocessing system for performing a bioprocess

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3476895D1 (en) * 1984-11-22 1989-04-06 Personal Diagnostics Inc Self-sufficient incubation assembly
AU6355790A (en) * 1989-08-04 1991-03-11 Peter Grandics An integrated cell culture-protein purification system for the automated production and purification of cell culture products
EP0620939A4 (en) * 1991-11-25 1996-05-29 Cornell Res Foundation Inc Automated multicompartmental cell culture system.
US5612188A (en) * 1991-11-25 1997-03-18 Cornell Research Foundation, Inc. Automated, multicompartmental cell culture system
US5352414A (en) * 1992-12-30 1994-10-04 Rothenberg Barry E Incubator unit and filter system
US5424209A (en) * 1993-03-19 1995-06-13 Kearney; George P. Automated cell culture and testing system

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010086465A1 (es) 2009-01-30 2010-08-05 Emilio Mateu Sentamans Método y equipo modular para el procesamiento y almacenamiento de cultivos celulares

Also Published As

Publication number Publication date
EP0832182B1 (en) 2001-08-16
EP0832182A1 (en) 1998-04-01
CA2223525A1 (en) 1996-12-19
DE69614535D1 (de) 2001-09-20
CA2223525C (en) 2008-12-23
JP3880622B2 (ja) 2007-02-14
ATE204322T1 (de) 2001-09-15
DE69614535T2 (de) 2002-06-06
WO1996040858A1 (en) 1996-12-19
JPH11507229A (ja) 1999-06-29

Similar Documents

Publication Publication Date Title
ES2162081T3 (es) Aparato y procedimiento para el mantenimiento y crecimiento de celulas biologicas.
Kanda et al. Behavior of arterial wall cells cultured on periodically stretched substrates
ATE231912T1 (de) Zell/gewebekultursystem und -verfahren
ATE270082T1 (de) Verfahren zur bereitung und transplantation von flachen implantaten und chirurgische geräte dafür
EP0682697A4 (en) METHOD AND DEVICE FOR ANCHORING AND SUSPENSING CELL CULTURES.
Cohen et al. Models of wound healing
WO1988006402A1 (en) Integument and method for culturing organic material
ES2175087T3 (es) Compuestos triciclicos utiles en el tratamiento de trastornos de proliferacion celular.
AU2595195A (en) Method and apparatus monitoring viability of transplantable organs
CA2244659A1 (en) Biological reactor for the cultivation of cells
BR8907642A (pt) Matriz tridimensional de estroma,culturas tridimensionais de celulas,sistema de cultura tridimensional,processos para cultura de celulas,processo para transplante de implante de celulas,processo para implante de celulas de estroma in vivo,processo para teste de citotoxicidade de uma substancia,processo para teste do efeito de um medicamento,processo para diagnostico ou monitoracao demalignidade,processo para cultura de celulas de engenharia genetica,processo para analise de doenca ou condicao de um paciente,processo para estudo de mecanismos de doenca,processo para testar a capacidade de uma substancia de a
NO995240D0 (no) Innretning for dyrking og/eller behandling av celler
NO922887D0 (no) Fremgangsmaate for dannelse av cellemasse og/eller fermenteringsprodukter under sterile forhold samt anordning for utfoerelse av fremgangsmaaten
CA1267623C (en) CELL CULTURE FILTER APPARATUS AND METHOD OF USE
DE3781811D1 (de) Perifusionsgeraet fuer die zuechtung lebender zellen und verfahren zur perifusions-kultivierung.
KR880007714A (ko) 구군 식물의 증식방법
RU94033868A (ru) Способ воздействия на микрообъект магнитным полем и устройство для его осуществления
CA2540156A1 (en) Apparatus and methods for selecting capacitated spermatozoa and uses thereof
ATE220713T1 (de) Verfahren zur identifizierung von bakterien und zur bestimmung von deren empfindlichkeit gegen antibiotika sowie vorrichtung und messträger dafür
Stodieck et al. Commercial investigation results for the generic bioprocessing apparatus flown on United States Microgravity Laboratory-1
SU882525A1 (ru) Способ лечени ран
Grymes et al. A Study of Parameters Affecting Fibroblast Morphology in Response to an Applied Mechanical Force
SU1675727A1 (ru) Способ подготовки культуры клеток к электронно-радиоавтографическому исследованию
EP0850297A1 (en) Determining nonparaffinophilic microorganisms
Weber Models of glycolysis: glyceraldehyde as a source of energy and monomers for prebiotic condensation reactions

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 832182

Country of ref document: ES