ES2166090T3 - Composiciones transdermicas que contienen levosimendan. - Google Patents
Composiciones transdermicas que contienen levosimendan.Info
- Publication number
- ES2166090T3 ES2166090T3 ES97929320T ES97929320T ES2166090T3 ES 2166090 T3 ES2166090 T3 ES 2166090T3 ES 97929320 T ES97929320 T ES 97929320T ES 97929320 T ES97929320 T ES 97929320T ES 2166090 T3 ES2166090 T3 ES 2166090T3
- Authority
- ES
- Spain
- Prior art keywords
- compositions containing
- transdermal compositions
- transdermal
- levosimenden
- containing levosimendan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- WHXMKTBCFHIYNQ-SECBINFHSA-N levosimendan Chemical compound C[C@@H]1CC(=O)NN=C1C1=CC=C(NN=C(C#N)C#N)C=C1 WHXMKTBCFHIYNQ-SECBINFHSA-N 0.000 title 1
- 229960000692 levosimendan Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000006071 cream Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- 125000005638 hydrazono group Chemical group 0.000 abstract 1
- 239000006210 lotion Substances 0.000 abstract 1
- CUONGYYJJVDODC-UHFFFAOYSA-N malononitrile Chemical compound N#CCC#N CUONGYYJJVDODC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002674 ointment Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 230000037317 transdermal delivery Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9614098.3A GB9614098D0 (en) | 1996-07-05 | 1996-07-05 | Transdermal delivery of levosimendan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2166090T3 true ES2166090T3 (es) | 2002-04-01 |
Family
ID=10796379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97929320T Expired - Lifetime ES2166090T3 (es) | 1996-07-05 | 1997-06-26 | Composiciones transdermicas que contienen levosimendan. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6183771B1 (de) |
| EP (1) | EP0941063B1 (de) |
| JP (1) | JP4148996B2 (de) |
| AT (1) | ATE206910T1 (de) |
| AU (1) | AU720504B2 (de) |
| DE (1) | DE69707493T2 (de) |
| DK (1) | DK0941063T3 (de) |
| ES (1) | ES2166090T3 (de) |
| GB (1) | GB9614098D0 (de) |
| GR (1) | GR3037083T3 (de) |
| NZ (1) | NZ333306A (de) |
| PT (1) | PT941063E (de) |
| WO (1) | WO1998001111A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI973804A7 (fi) * | 1997-09-26 | 1999-03-27 | Orion Yhtymae Oy | Levosimendaanin oraalisia koostumuksia |
| FI974578L (fi) * | 1997-12-19 | 1999-06-20 | Orion Yhtymae Oyj | Menetelmä levosimendaanin antamiseksi |
| FI980902A7 (fi) * | 1998-04-23 | 1999-10-24 | Orion Yhtymae Oyj | Levosimendaanin stabiileja koostumuksia |
| FI980901A7 (fi) | 1998-04-23 | 1999-10-24 | Orion Yhtymae Oyj | Levosimendaania säädellysti vapauttavia oraalisia koostumuksia |
| FI105389B (fi) * | 1998-04-23 | 2000-08-15 | Orion Yhtymae Oyj | Menetelmä levosimendaaniannon siedettävyyden seuraamiseksi |
| FI104718B (fi) * | 1998-06-18 | 2000-03-31 | Orion Yhtymae Oyj | [[4-(2-atsido-3-metyyli-5-oksotetrahydrofuran-2-yyli)fenyyli]hydratsono]propaanidinitriili käytettäväksi referenssiaineena levosimendaanierien analyysissä |
| FI981473L (fi) * | 1998-06-25 | 1999-12-26 | Orion Yhtymae Oyj | Menetelmä pulmonaalihypertension hoitamiseksi |
| CA2359640C (en) * | 1999-02-05 | 2008-11-18 | Cipla Limited | Topical sprays |
| EP1169025B1 (de) * | 1999-04-01 | 2005-08-24 | Alza Corporation | Transdermale vorrichtung zur arzneistoffverabreichung mit einem polyurethanwirkstoffreservoir |
| GB9915179D0 (en) * | 1999-06-29 | 1999-09-01 | Orion Corp | A method for the treatment or prevention of coronary graft vasospasm |
| FI109659B (fi) * | 1999-09-10 | 2002-09-30 | Orion Yhtymae Oyj | Levosimendaanin farmaseuttisia liuoksia |
| FI20002755A0 (fi) | 2000-12-15 | 2000-12-15 | Orion Yhtymae Oyj | Menetelmä erektiilin dysfunktion hoitamiseen |
| KR100554649B1 (ko) * | 2003-06-09 | 2006-02-24 | 주식회사 아이센스 | 전기화학적 바이오센서 |
| EP2285362B1 (de) | 2008-06-19 | 2017-08-09 | LTS LOHMANN Therapie-Systeme AG | Zusammensetzung zur transdermalen verabreichung kationischer wirkstoffe |
| DE102009008256A1 (de) * | 2009-02-10 | 2010-08-12 | Lts Lohmann Therapie-Systeme Ag | Prodrugs vom Typ N-hydroxylierter Amidine, Guanidine und/oder Aminohydrazone zur Applikation über die Haut |
| JP5542791B2 (ja) * | 2009-02-18 | 2014-07-09 | 久光製薬株式会社 | 経皮吸収製剤 |
| WO2012093404A2 (en) | 2011-01-03 | 2012-07-12 | Gufic Biosciences Limited | Parenteral formulations of levosimendan |
| CA3036841A1 (en) | 2016-09-13 | 2018-03-22 | The Regents Of The University Of Michigan | Fused 1,4-diazepines as bet protein degraders |
| US11969424B2 (en) | 2019-12-16 | 2024-04-30 | Tenax Therapeutics, Inc. | Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (PH-HFpEF) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5124157A (en) | 1989-08-18 | 1992-06-23 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
| GB2251615B (en) | 1991-01-03 | 1995-02-08 | Orion Yhtymae Oy | (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile |
| GB2256135B (en) | 1991-05-31 | 1995-01-18 | Orion Yhtymae Oy | Transdermal administration of 4-substituted imidazoles |
| GB9111732D0 (en) | 1991-05-31 | 1991-07-24 | Orion Yhtymae Oy | The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs |
| GB2266841A (en) | 1992-05-06 | 1993-11-17 | Orion Yhtymae Oy | Compounds for use as anti-ischemic medicaments |
-
1996
- 1996-07-05 GB GBGB9614098.3A patent/GB9614098D0/en active Pending
-
1997
- 1997-06-26 AT AT97929320T patent/ATE206910T1/de not_active IP Right Cessation
- 1997-06-26 AU AU33459/97A patent/AU720504B2/en not_active Ceased
- 1997-06-26 ES ES97929320T patent/ES2166090T3/es not_active Expired - Lifetime
- 1997-06-26 WO PCT/FI1997/000412 patent/WO1998001111A1/en not_active Ceased
- 1997-06-26 JP JP50482598A patent/JP4148996B2/ja not_active Expired - Fee Related
- 1997-06-26 US US09/214,295 patent/US6183771B1/en not_active Expired - Lifetime
- 1997-06-26 PT PT97929320T patent/PT941063E/pt unknown
- 1997-06-26 NZ NZ333306A patent/NZ333306A/xx unknown
- 1997-06-26 EP EP97929320A patent/EP0941063B1/de not_active Expired - Lifetime
- 1997-06-26 DK DK97929320T patent/DK0941063T3/da active
- 1997-06-26 DE DE69707493T patent/DE69707493T2/de not_active Expired - Fee Related
-
2001
- 2001-10-31 GR GR20010401956T patent/GR3037083T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000514081A (ja) | 2000-10-24 |
| DK0941063T3 (da) | 2001-12-17 |
| JP4148996B2 (ja) | 2008-09-10 |
| US6183771B1 (en) | 2001-02-06 |
| PT941063E (pt) | 2002-04-29 |
| EP0941063A1 (de) | 1999-09-15 |
| NZ333306A (en) | 2000-03-27 |
| AU720504B2 (en) | 2000-06-01 |
| DE69707493T2 (de) | 2002-04-11 |
| ATE206910T1 (de) | 2001-11-15 |
| DE69707493D1 (de) | 2001-11-22 |
| GB9614098D0 (en) | 1996-09-04 |
| GR3037083T3 (en) | 2002-01-31 |
| AU3345997A (en) | 1998-02-02 |
| WO1998001111A1 (en) | 1998-01-15 |
| EP0941063B1 (de) | 2001-10-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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