ES2167332T3 - Procedimiento y sistemas para el implante de celulas vivas en organismos huespedes. - Google Patents

Procedimiento y sistemas para el implante de celulas vivas en organismos huespedes.

Info

Publication number
ES2167332T3
ES2167332T3 ES93908495T ES93908495T ES2167332T3 ES 2167332 T3 ES2167332 T3 ES 2167332T3 ES 93908495 T ES93908495 T ES 93908495T ES 93908495 T ES93908495 T ES 93908495T ES 2167332 T3 ES2167332 T3 ES 2167332T3
Authority
ES
Spain
Prior art keywords
implant
host
cells
methodologies
boundary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93908495T
Other languages
English (en)
Inventor
James H Brauker
Ronald S Hill
Robert C Johnson
Laura A Martinson
William D Johnston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Application granted granted Critical
Publication of ES2167332T3 publication Critical patent/ES2167332T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

LOS ENSAMBLAJES DE IMPLANTACION Y LAS METODOLOGIAS PROPORCIONAN INMUNO-PROTECCION PARA ALOINJERTOS, XENOINJERTOS E ISOINJERTOS IMPLANTADOS. LOS ENSAMBLAJES Y LAS METODOLOGIAS ESTABLECEN UNA FRONTERA MEJORADA ENTRE LA CELULA ANFITRIONA Y LA IMPLANTADA (12). LA FRONTERA TIENE EL TAMAÑO DE UN PORO, UNA RESISTENCIA MAXIMA Y UN VALOR DE TRANSITO METABOLICO QUE ASEGURA LA SUPERVIVENCIA DE LA CELULA DURANTE EL PERIODO CRITICO DE ISQUEMIA Y DESPUES. LA FRONTERA PERMITE LA FABRICACION Y EL USO CLINICO DE ENSAMBLAJES DE IMPLANTE Y METODOLOGIAS QUE PUEDAN CONTENER SUFICIENTES CELULAS PARA TENER UN VALOR TERAPEUTICO PARA LA ANFITRIONA, Y SIN EMBARGO OCUPAR UN AREA RELATIVAMENTE PEQUEÑA Y COMPACTA DENTRO DE LA ANFITRIONA.
ES93908495T 1992-04-01 1993-03-25 Procedimiento y sistemas para el implante de celulas vivas en organismos huespedes. Expired - Lifetime ES2167332T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86151292A 1992-04-01 1992-04-01

Publications (1)

Publication Number Publication Date
ES2167332T3 true ES2167332T3 (es) 2002-05-16

Family

ID=25336012

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93908495T Expired - Lifetime ES2167332T3 (es) 1992-04-01 1993-03-25 Procedimiento y sistemas para el implante de celulas vivas en organismos huespedes.

Country Status (9)

Country Link
EP (1) EP0676935B1 (es)
JP (1) JPH08500255A (es)
AT (1) ATE208169T1 (es)
CA (1) CA2132016A1 (es)
DE (1) DE69331108T2 (es)
DK (1) DK0676935T3 (es)
ES (1) ES2167332T3 (es)
PT (1) PT676935E (es)
WO (1) WO1993019701A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012074349A1 (es) * 2010-11-30 2012-06-07 Val De Bio, S. De R.L. De Cv Dispositivo plano para favorecer el trasplante de material biológico

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5725577A (en) * 1993-01-13 1998-03-10 Saxon; Allen Prosthesis for the repair of soft tissue defects
WO1995001810A1 (en) * 1993-07-07 1995-01-19 Smith & Nephew Plc Implantable prosthesis, kit and device for manufacturing the same
AU678843B2 (en) * 1993-08-10 1997-06-12 W.L. Gore & Associates, Inc. Cell encapsulating device
US5549675A (en) * 1994-01-11 1996-08-27 Baxter International, Inc. Method for implanting tissue in a host
EP1174156A2 (en) * 1994-01-11 2002-01-23 Baxter International Inc. Ported tissue implant systems and methods of using same
WO1996032076A1 (en) * 1995-04-11 1996-10-17 Baxter Internatonal Inc. Tissue implant systems
EP0747046A3 (en) * 1995-05-19 1997-12-03 Baxter International Inc. Permeable immunoisolation membrane structures for implantation of cells in host tissue
WO1997010807A1 (en) * 1995-09-22 1997-03-27 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
US7192450B2 (en) 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US6862465B2 (en) 1997-03-04 2005-03-01 Dexcom, Inc. Device and method for determining analyte levels
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US6741877B1 (en) 1997-03-04 2004-05-25 Dexcom, Inc. Device and method for determining analyte levels
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US6702857B2 (en) 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9247901B2 (en) 2003-08-22 2016-02-02 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
US7134999B2 (en) 2003-04-04 2006-11-14 Dexcom, Inc. Optimized sensor geometry for an implantable glucose sensor
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
JP4708342B2 (ja) 2003-07-25 2011-06-22 デックスコム・インコーポレーテッド 埋設可能な装置に用いる酸素増大膜システム
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US7494465B2 (en) 2004-07-13 2009-02-24 Dexcom, Inc. Transcutaneous analyte sensor
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP2239567B1 (en) 2003-12-05 2015-09-02 DexCom, Inc. Calibration techniques for a continuous analyte sensor
WO2005079257A2 (en) 2004-02-12 2005-09-01 Dexcom, Inc. Biointerface with macro- and micro- architecture
US7857760B2 (en) 2004-07-13 2010-12-28 Dexcom, Inc. Analyte sensor
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
WO2006127694A2 (en) 2004-07-13 2006-11-30 Dexcom, Inc. Analyte sensor
US8989833B2 (en) 2004-07-13 2015-03-24 Dexcom, Inc. Transcutaneous analyte sensor
US8744546B2 (en) 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
US20200037874A1 (en) 2007-05-18 2020-02-06 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
KR101395712B1 (ko) * 2013-03-18 2014-05-19 주식회사 엘앤씨바이오 진피조직체의 동결건조용 지그
JP7088564B2 (ja) * 2016-11-10 2022-06-21 ヴィアサイト，インコーポレイテッド 細胞送達装置におけるｐｄｘ１膵臓内胚葉細胞及びその方法
WO2020017195A1 (ja) * 2018-07-17 2020-01-23 株式会社日立製作所 移植用細胞収容装置、移植用細胞収容システム及び酸素供給装置

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4298002A (en) * 1979-09-10 1981-11-03 National Patent Development Corporation Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation
US4353888A (en) * 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4378016A (en) * 1981-07-15 1983-03-29 Biotek, Inc. Artificial endocrine gland containing hormone-producing cells
US4689293A (en) * 1983-06-06 1987-08-25 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4806355A (en) * 1983-06-06 1989-02-21 Connaught Laboratories Limited Microencapsulation of living tissue and cells
WO1986004783A1 (en) * 1985-02-26 1986-08-28 Glaser Bert M Neovascularization inhibitors and methods for their production and use
WO1989012645A1 (en) * 1988-06-22 1989-12-28 Synergen, Inc. Angiogenic potentiating peptides which potentiate angiogenic factors
JP3073766B2 (ja) * 1989-04-25 2000-08-07 チルドレンズ メディカル センター コーポレイション 重合マトリックス上の大容量の細胞の移植方法
WO1991000119A1 (en) * 1989-06-30 1991-01-10 Baxter International Inc. Implantable device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012074349A1 (es) * 2010-11-30 2012-06-07 Val De Bio, S. De R.L. De Cv Dispositivo plano para favorecer el trasplante de material biológico

Also Published As

Publication number Publication date
WO1993019701A1 (en) 1993-10-14
DK0676935T3 (da) 2001-12-27
EP0676935B1 (en) 2001-11-07
EP0676935A4 (en) 1995-06-22
ATE208169T1 (de) 2001-11-15
PT676935E (pt) 2002-04-29
JPH08500255A (ja) 1996-01-16
DE69331108T2 (de) 2002-07-04
CA2132016A1 (en) 1994-10-14
EP0676935A1 (en) 1995-10-18
DE69331108D1 (de) 2001-12-13

Similar Documents

Publication Publication Date Title
DK0676935T3 (da) Angiogeniske vævsimplantatsystemer
ES554090A0 (es) Procedimiento de obtencion de un deposito para farmacos implantable en el cuerpo para la liberacion retardada controlada de ciclostaticos.
DE69329651D1 (de) Wässrige arzneizusammensetzung, welche das menschliche wachstumshormon enthält
GB2045083B (en) Element for implantation in body tissue particularly bone tissue
IT8520110A0 (it) Elettrodo, apparecchiatura e defibrillazione per l'impianto in corpi umani o animali.
DE59003981D1 (de) Wirbelkörperimplantat.
ATE121089T1 (de) Optisch aktives 5h-pyrrolo(3,4-b>pyrazinderivat, seine herstellung und pharmazeutische zubereitungen die es enthalten.
GB9206504D0 (en) Heteromorphic sponges as wound implants
DE3689167D1 (de) Aktives Implantat.
EP0276536A3 (en) Use of buspirone for the improvement of short term memory
AU555952B2 (en) Collagen implant containing active ingredient for implantation in bones
FR2662698B1 (es)
DK0452190T3 (da) Lagersystem med hosliggende skabe til anvendelse navnlig i banegårde eller lufthavne
AR229849A1 (es) Procedimiento para la obtencion de un farmaco-deposito implantable y resorbible por el cuerpo
SE8701004D0 (sv) Method for therapy of leukemias and certain other malignancies
GB9009389D0 (en) Treatment
GR3017152T3 (en) Anti-herpes castanospermine esters.
ZA81473B (en) 5-amino-tetayole derivatives of retinoic acids, their preparation and pharmaceutical formulations containg these derivatives
ZA849576B (en) 1,7-diphenyl-3-methyllaza-7-cyano-8-methylnonane for use in the treatment of diseases
GR3007611T3 (es)
ES2138053T3 (es) Formulacion insecticida solida.
ES2094240T3 (es) Utilizacion de diol diesteres en los alimentos para perros y gatos.
EP0565674A4 (es)
Dougherty Future of photoradiation therapy in the treatment of cancer.
MX9200040A (es) Factor del crecimiento del fibroblasto basico humano recombinante y metodo para su obtencion.