ES2170628B1 - Pequeños inhibidores de moleculas de la actividad de enzimas de rotamasa - Google Patents

Pequeños inhibidores de moleculas de la actividad de enzimas de rotamasa

Info

Publication number
ES2170628B1
ES2170628B1 ES9950069A ES9950069A ES2170628B1 ES 2170628 B1 ES2170628 B1 ES 2170628B1 ES 9950069 A ES9950069 A ES 9950069A ES 9950069 A ES9950069 A ES 9950069A ES 2170628 B1 ES2170628 B1 ES 2170628B1
Authority
ES
Spain
Prior art keywords
activity
enzymes
rotamasa
molecules
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9950069A
Other languages
English (en)
Other versions
ES2170628A1 (es
Inventor
Gregory S Hamilton
Joseph P Steiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Corp of North America
Original Assignee
Guilford Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/479,436 external-priority patent/US5614547A/en
Priority claimed from US08/650,461 external-priority patent/US5859031A/en
Application filed by Guilford Pharmaceuticals Inc filed Critical Guilford Pharmaceuticals Inc
Publication of ES2170628A1 publication Critical patent/ES2170628A1/es
Application granted granted Critical
Publication of ES2170628B1 publication Critical patent/ES2170628B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Esta invención se refiere a compuestos de esteres de prolilo N-glioxilo neurotróficos que tengan una afinidad para las inmunofilinas del tipo FKBP, su preparación y uso como inhibidores de la actividad de enzimas asociadas con las proteínas inmunofilinas, y particularmente inhibidores de la actividad de la enzima de rotamasa o isomerasa de prolilopeptidilo.
ES9950069A 1995-06-07 1996-06-05 Pequeños inhibidores de moleculas de la actividad de enzimas de rotamasa Expired - Fee Related ES2170628B1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/479,436 US5614547A (en) 1995-06-07 1995-06-07 Small molecule inhibitors of rotamase enzyme
US08/650,461 US5859031A (en) 1995-06-07 1996-05-21 Small molecule inhibitors of rotamase enzyme activity
ES009650030A ES2131457B1 (es) 1995-06-07 1996-06-05 Pequeños inhibidores de moleculas de la actividad de enzimas de rotamasa.

Publications (2)

Publication Number Publication Date
ES2170628A1 ES2170628A1 (es) 2002-08-01
ES2170628B1 true ES2170628B1 (es) 2003-06-16

Family

ID=27240554

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9950069A Expired - Fee Related ES2170628B1 (es) 1995-06-07 1996-06-05 Pequeños inhibidores de moleculas de la actividad de enzimas de rotamasa

Country Status (1)

Country Link
ES (1) ES2170628B1 (es)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2091194A1 (en) * 1992-04-08 1993-10-09 Richard D. Connell 2-oxo-ethyl derivatives as immunosuppressants

Also Published As

Publication number Publication date
ES2170628A1 (es) 2002-08-01

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