ES2170763T3 - Aparato y procedimiento de separacion de liquidos. - Google Patents
Aparato y procedimiento de separacion de liquidos.Info
- Publication number
- ES2170763T3 ES2170763T3 ES94203381T ES94203381T ES2170763T3 ES 2170763 T3 ES2170763 T3 ES 2170763T3 ES 94203381 T ES94203381 T ES 94203381T ES 94203381 T ES94203381 T ES 94203381T ES 2170763 T3 ES2170763 T3 ES 2170763T3
- Authority
- ES
- Spain
- Prior art keywords
- phase
- liquid
- piston body
- chamber
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
- B04B1/04—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles with inserted separating walls
- B04B1/06—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles with inserted separating walls of cylindrical shape
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
- B04B1/02—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles without inserted separating walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B7/00—Elements of centrifuges
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
- B04B2005/0485—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with a displaceable piston in the centrifuge chamber
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Ecology (AREA)
- Centrifugal Separators (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- External Artificial Organs (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
EN UN PROCESO PARA SEPARAR UNA MUESTRA LIQUIDA QUE TENGA PARTES DE FASE DE DENSIDADES DIFERENTES MEDIANTE SEPARACION CENTRIFUGA SE EMPLEA UN SEPARADOR DE FASE. EL CONTENEDOR SEPARADOR DE FASE COMPRENDE UN ALOJAMIENTO QUE TIENE PAREDES CILINDRICAS CONCENTRICAS INTERNA Y EXTERNA QUE DEFINEN UN EJE LONGITUDINAL Y UNA PARED SUPERIOR Y ADEMAS UN CUERPO DE PISTON QUE CONSTITUYE UNA PARED DE FONDO DEL ALOJAMIENTO. EL CUERPO DEL PISTON DEFINE JUNTO CON LA PARED CILINDRICA EXTERIOR, LA PARED CILINDRICA INTERIOR Y LA PARED SUPERIOR, UNA CAMARA ANULAR PARA RECIBIR LA MUESTRA DE LIQUIDO. EL CUERPO DEL PISTON PUEDE DESPLAZARSE DENTRO DE LA CAMARA ANULA PARA DRENAR UNA PARTE DE LA FASE SEPARADA DE LA MUESTRA DE LIQUIDO A TRAVES DE UN MEDIO DE CONDUCCION DE DRENAJE QUE COMUNICA CON LA CAMARA ANULAR. LA CAMARA DE SEPARACION DE FASES COMPRENDE ADEMAS UNA CAMARA DE REACCION EN LA CUAL LAS PARTES DE LA FASE EXPUESTAS DE LA CAMARA ANULAR SE PROCESAN. EL APARATO INCLUYE ADEMAS UN MEDIO PARA EL SUMINISTRO DE LIQUIDO PARA SUMINISTRAR LA MUESTRA DE LIQUIDO A LA CAMARA ANULAR, UN MOTOR PARA HACER GIRAR EL CONTENEDOR DE SEPARACION DE FASES ALREDEDOR DE SU EJE LONGITUDINAL A UNA VELOCIDAD ROTACIONAL QUE PROVOQUE LA SEPARACION DE LA MUESTRA DE LIQUIDO EN DIFERENTES PARTES DE FASE, Y UN DISPOSITIVO DE ACCIONAMIENTO PARA DESPLAZAR EL CUERPO DEL PISTON EN EL INTERIOR DE LA CAMARA ANULAR.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15598493A | 1993-11-19 | 1993-11-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2170763T3 true ES2170763T3 (es) | 2002-08-16 |
Family
ID=22557593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES94203381T Expired - Lifetime ES2170763T3 (es) | 1993-11-19 | 1994-11-21 | Aparato y procedimiento de separacion de liquidos. |
Country Status (26)
| Country | Link |
|---|---|
| US (6) | US5603845A (es) |
| EP (2) | EP0654669B1 (es) |
| JP (1) | JP3745397B2 (es) |
| KR (1) | KR950013582A (es) |
| CN (1) | CN1044977C (es) |
| AT (1) | ATE213329T1 (es) |
| AU (1) | AU688390B2 (es) |
| BR (1) | BR9404484A (es) |
| CA (1) | CA2136148C (es) |
| CZ (1) | CZ280694A3 (es) |
| DE (1) | DE69429852T2 (es) |
| DK (1) | DK0654669T3 (es) |
| ES (1) | ES2170763T3 (es) |
| FI (2) | FI114340B (es) |
| HU (1) | HU215246B (es) |
| IL (1) | IL111524A (es) |
| MX (1) | MXPA99004700A (es) |
| NO (1) | NO314715B1 (es) |
| NZ (1) | NZ264859A (es) |
| PL (1) | PL176963B1 (es) |
| PT (1) | PT654669E (es) |
| RU (1) | RU2133468C1 (es) |
| SG (1) | SG49212A1 (es) |
| SK (1) | SK138394A3 (es) |
| UA (1) | UA27898C2 (es) |
| ZA (1) | ZA948564B (es) |
Families Citing this family (153)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU700195B2 (en) * | 1994-08-29 | 1998-12-24 | Akzo Nobel N.V. | Device for use in the isolation of a biological material such as nucleic acid |
| NZ298284A (en) * | 1994-12-02 | 1999-02-25 | Bristol Myers Squibb Co | Separating fibrin monomer from plasma comprising the step of converting to non-crosslinked fibrin polymer during centrifugation |
| PL320512A1 (en) * | 1994-12-02 | 1997-10-13 | Bristol Myers Squibb Co | System for feeding a reagent into a centrifuge |
| US5926387A (en) * | 1995-06-30 | 1999-07-20 | Beckman Instruments, Inc. | Ultracentrifuge operation by computer system |
| USD420444S (en) | 1995-12-07 | 2000-02-08 | Bristol-Myers Squibb Company | Blood processor |
| US6123655A (en) * | 1996-04-24 | 2000-09-26 | Fell; Claude | Cell separation system with variable size chamber for the processing of biological fluids |
| US6132598A (en) * | 1997-01-08 | 2000-10-17 | Bristol-Myers Squibb Company | Centrifuge apparatus with temperature control means |
| US5955026A (en) * | 1997-01-08 | 1999-09-21 | Bristol-Myers Squibb Company | Detecting the thickness of fibrin polymer using an optical device |
| CA2277860C (en) * | 1997-01-08 | 2005-11-29 | Bristol-Myers Squibb Company | Centrifuge apparatus for separating blood |
| WO1998030304A1 (en) * | 1997-01-08 | 1998-07-16 | Bristol-Myers Squibb Company | A centrifuge apparatus with temperature control means |
| US6979307B2 (en) | 1997-06-24 | 2005-12-27 | Cascade Medical Enterprises Llc | Systems and methods for preparing autologous fibrin glue |
| WO1999004837A1 (en) * | 1997-07-25 | 1999-02-04 | Bristol-Myers Squibb Company | Blood product delivery system |
| US6846298B1 (en) | 1997-07-25 | 2005-01-25 | Bristol-Myers Squibb Company | Blood product delivery system |
| EP1077733B1 (en) | 1999-03-15 | 2006-03-01 | Implant Innovations, Inc. | Platelet collection system |
| US6393369B1 (en) * | 1999-04-30 | 2002-05-21 | Bristol-Myers Squibb Company | System for control of blood processor |
| ATE337806T1 (de) * | 1999-07-08 | 2006-09-15 | Implant Innovations Inc | Spritzenkit für die konzentration von thrombozyten und verfahren |
| US6716187B1 (en) * | 1999-07-08 | 2004-04-06 | Implant Innovations, Inc. | Platelet concentration syringe kit |
| US6387263B1 (en) * | 1999-09-02 | 2002-05-14 | Bristol-Myers Squibb Company | Apparatus and methods for preparing plasma solutions from blood with improved separation of plasma |
| US6524231B1 (en) * | 1999-09-03 | 2003-02-25 | Baxter International Inc. | Blood separation chamber with constricted interior channel and recessed passage |
| US7033501B1 (en) * | 1999-09-24 | 2006-04-25 | Bristol-Myers Squibb Company | Centrifuge apparatus and method with improved temperature control |
| US7045283B2 (en) * | 2000-10-18 | 2006-05-16 | The Regents Of The University Of California | Methods of high-throughput screening for internalizing antibodies |
| US6835316B2 (en) | 2001-04-09 | 2004-12-28 | Medtronic, Inc. | Clam shell blood reservoir holder with index line |
| US6596181B2 (en) | 2001-04-09 | 2003-07-22 | Medtronic, Inc. | Hard shell disposable reservoir having complex internal design for use in a centrifuge |
| US6579219B2 (en) * | 2001-04-09 | 2003-06-17 | Medtronic, Inc. | Centrifuge bag and methods of use |
| US6610002B2 (en) | 2001-04-09 | 2003-08-26 | Medtronic, Inc. | Method for handling blood sample to ensure blood components are isolated |
| US6612975B2 (en) | 2001-04-09 | 2003-09-02 | Medtronic, Inc. | Blood centrifuge with an enhanced internal drive assembly |
| US6790371B2 (en) * | 2001-04-09 | 2004-09-14 | Medtronic, Inc. | System and method for automated separation of blood components |
| US6582350B2 (en) | 2001-04-09 | 2003-06-24 | Medtronic, Inc. | Centrifuge container having curved linear shape |
| US20020144939A1 (en) * | 2001-04-09 | 2002-10-10 | Dolecek Victor D. | Miniaturized blood centrifuge having side mounted motor with belt drive |
| US6589155B2 (en) | 2001-04-09 | 2003-07-08 | Medtronic, Inc. | Miniaturized blood centrifuge having side mounted motor with belt drive |
| AU2002256086A1 (en) * | 2001-04-09 | 2002-10-21 | Medtronic, Inc. | Methods of isolating blood components using a centrifuge and uses thereof |
| US6605028B2 (en) | 2001-04-09 | 2003-08-12 | Medtronic, Inc. | Blood centrifuge having integral heating to control cellular component temperature |
| US7011852B2 (en) * | 2001-05-07 | 2006-03-14 | Hemogenesis, Llc | Separation of platelets from whole blood for use as a healant |
| US8101077B2 (en) * | 2001-05-07 | 2012-01-24 | Sivaprasad Sukavaneshvar | Device for separating platelets from fluid suspensions |
| US6890291B2 (en) * | 2001-06-25 | 2005-05-10 | Mission Medical, Inc. | Integrated automatic blood collection and processing unit |
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| US7211037B2 (en) * | 2002-03-04 | 2007-05-01 | Therakos, Inc. | Apparatus for the continuous separation of biological fluids into components and method of using same |
| US7479123B2 (en) | 2002-03-04 | 2009-01-20 | Therakos, Inc. | Method for collecting a desired blood component and performing a photopheresis treatment |
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| US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
| US7992725B2 (en) | 2002-05-03 | 2011-08-09 | Biomet Biologics, Llc | Buoy suspension fractionation system |
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| JP4875299B2 (ja) * | 2002-06-27 | 2012-02-15 | ベレッタ ロベルト | 液体成分を分離する方法及び装置 |
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- 1994-11-17 BR BR9404484A patent/BR9404484A/pt not_active Application Discontinuation
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