ES2170864T3 - Comprimidos que contienen una resina de intercambio de aniones. - Google Patents

Comprimidos que contienen una resina de intercambio de aniones.

Info

Publication number
ES2170864T3
ES2170864T3 ES96925987T ES96925987T ES2170864T3 ES 2170864 T3 ES2170864 T3 ES 2170864T3 ES 96925987 T ES96925987 T ES 96925987T ES 96925987 T ES96925987 T ES 96925987T ES 2170864 T3 ES2170864 T3 ES 2170864T3
Authority
ES
Spain
Prior art keywords
exchange resin
anion exchange
carbon atoms
alkyl group
tablets containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96925987T
Other languages
English (en)
Inventor
Takeshi Goto
Tatsuya Meno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Application granted granted Critical
Publication of ES2170864T3 publication Critical patent/ES2170864T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • External Artificial Organs (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UNA RESINA DE INTERCAMBIO ANIONICO, DIOXIDO DE SILICONA, CELULOSA CRISTALINA Y TRANSPORTADORES FARMACEUTICAMENTE ACEPTABLES Y, MAS CONCRETAMENTE, A TABLETAS QUE CONTIENEN RESINA DE INTERCAMBIO ANIONICO PREPARADA MEZCLANDO RESINA DE INTERCAMBIO ANIONICO, DIOXIDO DE SILICONA Y CELULOSA CRISTALINA, SIN ADICION DE AGUA, Y CONFORMANDO LA MEZCLA EN FORMA DE TABLETAS. CON MAYOR PREFERENCIA, LA PRESENTE INVENCION SE REFIERE A DICHA COMPOSICION FARMACEUTICA O A DICHAS TABLETAS, EN LAS QUE LA RESINA DE INTERCAMBIO ANIONICO ES UNA RESINA DE INTERCAMBIO ANIONICO NO RETICULADA, REPRESENTADA MEDIANTE LA FORMULA (I): DONDE R 1 ES UN GRUPO ARALQUILO QUE TIENE ENTRE 7 Y 10 ATOMOS DE CARBONO O UN GRUPO ALQUILO QUE TIENE ENTRE 1-20 ATOMOS DE CARBONO; R 2 Y R 3 SON, CADA UNO INDEPE NDIENTEMENTE, IGUALES O DISTINTOS Y REPRESENTAN UN GRUPO ALQUILO INFERIOR QUE TIENE ENTRE 1-4 ATOMOS DE CARBONO; R 4 ES UN ATOMO DE HIDROGENO O UN GRUPO ALQUILICO INFERIOR QUE TIENE DE 1-4 ATOMOS DE CARBONO; X ES UN CONTRAION FISIOLOGICAMENTE ACEPTABLE; N ES UN ENTERO COMPRENDIDO ENTRE 1 Y 3; Y P ES UN GRADO MEDIO DE POLIMERIZACION ENTRE 10 Y 10.000.
ES96925987T 1995-08-02 1996-08-02 Comprimidos que contienen una resina de intercambio de aniones. Expired - Lifetime ES2170864T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22692695 1995-08-02

Publications (1)

Publication Number Publication Date
ES2170864T3 true ES2170864T3 (es) 2002-08-16

Family

ID=16852774

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96925987T Expired - Lifetime ES2170864T3 (es) 1995-08-02 1996-08-02 Comprimidos que contienen una resina de intercambio de aniones.

Country Status (13)

Country Link
US (1) US6022533A (es)
EP (1) EP0878198B1 (es)
KR (1) KR19990035884A (es)
CN (1) CN1079236C (es)
AT (1) ATE212852T1 (es)
AU (1) AU723249B2 (es)
CA (1) CA2228472C (es)
DE (1) DE69619139T2 (es)
DK (1) DK0878198T3 (es)
ES (1) ES2170864T3 (es)
PT (1) PT878198E (es)
TW (1) TW438608B (es)
WO (1) WO1997004789A1 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4010585B2 (ja) 1996-10-15 2007-11-21 久光製薬株式会社 陰イオン交換樹脂を含有する錠剤
US6673605B2 (en) 1997-03-05 2004-01-06 Japan Science & Technology Corporation Established cell line of microglia
TW592727B (en) * 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
WO1999024072A1 (fr) * 1997-11-10 1999-05-20 Hisamitsu Pharmaceutical Co., Inc. Agent a liberation prolongee pour medicaments et composition pharmaceutique a liberation prolongee
TW568788B (en) * 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
TWI241195B (en) * 2000-04-10 2005-10-11 Shionogi & Co Preventive agent for bile acidic diarrhea
JP4683812B2 (ja) * 2000-05-19 2011-05-18 大塚製薬株式会社 ヘリコバクター・ピロリ感染の診断用製剤
US7201891B1 (en) 2000-05-19 2007-04-10 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical preparation for the diagnosis of helicobacter pylori infection
DE10232113A1 (de) * 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
AU2004285450B2 (en) 2003-10-20 2010-01-14 Gregory K. Frykman Zeolite molecular sieves for the removal of toxins
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
JP2007031407A (ja) * 2005-07-29 2007-02-08 Shin Etsu Chem Co Ltd 低置換度セルロースエーテル含有コーティング用組成物及び不快な味が隠蔽されたフィルムコーティング製剤
WO2007027566A2 (en) * 2005-09-02 2007-03-08 Genzyme Corporation Method for removing phosphate and polymer used therefore
CA2622693C (en) 2005-09-15 2015-05-05 Genzyme Corporation Sachet formulation for amine polymers
WO2007130463A2 (en) * 2006-05-05 2007-11-15 Genzyme Corporation Amine condensation polymers as phosphate sequestrants
WO2008011047A2 (en) * 2006-07-18 2008-01-24 Genzyme Corporation Amine dendrimers
EP2066293A2 (en) 2006-09-29 2009-06-10 Genzyme Corporation Amide dendrimer compositions
US8163799B2 (en) 2006-12-14 2012-04-24 Genzyme Corporation Amido-amine polymer compositions
EP2114376A1 (en) * 2007-02-23 2009-11-11 Genzyme Corporation Amine polymer compositions
JP2010520285A (ja) * 2007-03-08 2010-06-10 ゲンズイメ コーポレーション スルホンポリマー組成物
EP2152277A1 (en) * 2007-04-27 2010-02-17 Genzyme Corporation Amido-amine dendrimer compositions
EP2217215A1 (en) * 2007-12-14 2010-08-18 Genzyme Corporation Coated pharmaceutical compositions
US20110142952A1 (en) * 2008-06-20 2011-06-16 Harris David J Pharmaceutical Compositions
CN116887866A (zh) 2020-12-03 2023-10-13 巴特尔纪念研究院 聚合物纳米颗粒和dna纳米结构组合物及用于非病毒递送的方法
JP2024516108A (ja) 2021-04-07 2024-04-12 バテル・メモリアル・インスティテュート 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
US12441996B2 (en) 2023-12-08 2025-10-14 Battelle Memorial Institute Use of DNA origami nanostructures for molecular information based data storage systems

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE445013B (sv) * 1979-06-21 1986-05-26 Landstingens Inkopscentral Medel for att forebygga eller behandla infektioner hos menniskor och djur
JPH01172324A (ja) * 1987-12-15 1989-07-07 Armour Internatl Co コレスチラミン組成物及びその製造法
US5178854A (en) * 1988-03-24 1993-01-12 Taisho Pharmaceutical Co., Ltd. Cholesterol-lowering agents
US4959219A (en) * 1988-08-15 1990-09-25 Fisons Corporation Coating barriers comprising ethyl cellulose
US5372823A (en) * 1989-03-16 1994-12-13 Bristol-Myers Squibb Company Direct compression cholestyramine tablet and solvent-free coating thereof
JPH02286621A (ja) * 1989-04-26 1990-11-26 Mitsubishi Kasei Corp 経口コレステロール低下剤
DE4121127A1 (de) * 1991-06-26 1993-01-14 Rettenmaier & Soehne Gmbh & Co Hilfsstoff zur trockenen direkttablettierung und verfahren zur herstellung desselben
US5800809A (en) * 1992-01-14 1998-09-01 Hisamitsu Pharmaceutical Co, Inc Non-crosslinked acrylic polymers and non-crosslinked anion exchange resins
EP0622078B1 (en) * 1992-01-14 1999-09-01 Hisamitsu Pharmaceutical Co., Inc. Cholesterol level depressant
JP3552285B2 (ja) * 1993-08-03 2004-08-11 三菱化学株式会社 経口コレステロール低下剤
US5709880A (en) * 1995-07-10 1998-01-20 Buckman Laboratories International, Inc. Method of making tabletized ionene polymers

Also Published As

Publication number Publication date
AU6630596A (en) 1997-02-26
AU723249B2 (en) 2000-08-24
EP0878198A4 (es) 1998-11-18
KR19990035884A (ko) 1999-05-25
WO1997004789A1 (en) 1997-02-13
EP0878198A1 (en) 1998-11-18
CA2228472C (en) 2003-06-17
CN1192150A (zh) 1998-09-02
DE69619139T2 (de) 2002-10-31
CA2228472A1 (en) 1997-02-13
EP0878198B1 (en) 2002-02-06
ATE212852T1 (de) 2002-02-15
DE69619139D1 (de) 2002-03-21
DK0878198T3 (da) 2002-04-22
PT878198E (pt) 2002-06-28
TW438608B (en) 2001-06-07
CN1079236C (zh) 2002-02-20
US6022533A (en) 2000-02-08
HK1012849A1 (en) 1999-08-13

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