ES2170865T3 - Composicion de farmaco para aliviar el dolor. - Google Patents
Composicion de farmaco para aliviar el dolor.Info
- Publication number
- ES2170865T3 ES2170865T3 ES96926846T ES96926846T ES2170865T3 ES 2170865 T3 ES2170865 T3 ES 2170865T3 ES 96926846 T ES96926846 T ES 96926846T ES 96926846 T ES96926846 T ES 96926846T ES 2170865 T3 ES2170865 T3 ES 2170865T3
- Authority
- ES
- Spain
- Prior art keywords
- pharmaco
- composition
- relief pain
- pain
- relief
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 abstract 2
- 230000000202 analgesic effect Effects 0.000 abstract 2
- 229940000425 combination drug Drugs 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
LA EFECTIVIDAD ANALGESICA DE UNA COMBINACION DE FARMACOS QUE CONTIENE AL MENOS UN ANALGESICO SE AUMENTA SIGNIFICATIVAMENTE MEDIANTE LA ADICION DE UN ANTAGONISTA DE RECEPTOR DE N ETIL D XTROMETORFANO O DEXTRORFANO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/510,546 US5840731A (en) | 1995-08-02 | 1995-08-02 | Pain-alleviating drug composition and method for alleviating pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2170865T3 true ES2170865T3 (es) | 2002-08-16 |
Family
ID=24031191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96926846T Expired - Lifetime ES2170865T3 (es) | 1995-08-02 | 1996-07-31 | Composicion de farmaco para aliviar el dolor. |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US5840731A (es) |
| EP (1) | EP0845989B1 (es) |
| JP (1) | JP3924321B2 (es) |
| AT (1) | ATE214277T1 (es) |
| AU (1) | AU6686596A (es) |
| CA (1) | CA2228249C (es) |
| DE (1) | DE69619832T2 (es) |
| DK (1) | DK0845989T3 (es) |
| ES (1) | ES2170865T3 (es) |
| PT (1) | PT845989E (es) |
| WO (1) | WO1997004780A2 (es) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPN605795A0 (en) | 1995-10-19 | 1995-11-09 | F.H. Faulding & Co. Limited | Analgesic pharmaceutical composition |
| JP2002514221A (ja) * | 1997-05-27 | 2002-05-14 | アルゴス ファーマシューティカル コーポレーション | カプサイシノイド及びその強化薬を含有する鎮痛薬組成物 |
| US5900420A (en) * | 1997-06-19 | 1999-05-04 | Cole; William L. | Method for treating chronic fatigue syndrome and fibromyalgia with buprenorphine |
| EP0906757B1 (en) * | 1997-09-16 | 2005-05-11 | Solvay Pharmaceuticals GmbH | Analgesic composition comprising moxonidine and an opioid analgesic agent |
| RS49982B (sr) * | 1997-09-17 | 2008-09-29 | Euro-Celtique S.A., | Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2 |
| US6245357B1 (en) * | 1998-03-06 | 2001-06-12 | Alza Corporation | Extended release dosage form |
| US8524277B2 (en) * | 1998-03-06 | 2013-09-03 | Alza Corporation | Extended release dosage form |
| US6007841A (en) * | 1998-03-13 | 1999-12-28 | Algos Pharmaceutical Corporation | Analgesic composition and method for treating pain |
| US6376467B1 (en) * | 1998-10-09 | 2002-04-23 | The Regents Of The University Of California | Use of inhibitors of protein kinase C epsilon to treat pain |
| EP1102589B1 (en) * | 1998-07-16 | 2006-11-02 | Memorial Sloan-Kettering Institute For Cancer Research | Topical compositions comprising an opioid analgesic and an nmda antagonist |
| US6890951B2 (en) | 1998-08-05 | 2005-05-10 | Brookhaven Science Associates Llc | Treatment of addiction and addiction-related behavior |
| KR20030060771A (ko) | 2000-04-28 | 2003-07-16 | 메모리얼 슬로안-케터링 캔서 센터 | 국소용 마취제/아편양약물 제제 및 이들의 용도 |
| HK1055078A1 (zh) * | 2000-06-09 | 2003-12-24 | The Regents Of The University Of California | 使用纳布啡和鸦片拮抗剂治疗疼痛的方法 |
| JP2005506292A (ja) * | 2001-03-08 | 2005-03-03 | エモリー ユニバーシティ | pHに依存するNMDAレセプターアンタゴニスト |
| US7820688B2 (en) * | 2001-04-27 | 2010-10-26 | Memorial Sloan-Kettering Cancer Center | Topical anesthetic/opioid formulations and uses thereof |
| NZ529661A (en) * | 2001-06-05 | 2006-03-31 | Control Delivery Systems | Sustained-release analgesic compounds |
| DE60143671D1 (de) * | 2001-06-07 | 2011-01-27 | Sang Christine | Behandlung von neuropathischen schmerzen mittels eines n-methyl-d-aspartate (nmda)-rezeptor-antagonists |
| JP2004537933A (ja) * | 2001-07-27 | 2004-12-16 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 看取者追跡システムを備える自動立体画像表示システム |
| AU2002336653A1 (en) * | 2001-10-24 | 2003-05-06 | Luciano Mastronardi | Management of postoperative pain |
| US20030118528A1 (en) * | 2001-11-19 | 2003-06-26 | Walters Kenneth A. | Topical delivery of codrugs |
| CA2473536A1 (en) * | 2002-01-16 | 2003-07-31 | Endo Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating disorders of the central nervous system |
| US7666876B2 (en) | 2002-03-19 | 2010-02-23 | Vernalis (R&D) Limited | Buprenorphine formulations for intranasal delivery |
| GB0206505D0 (en) * | 2002-03-19 | 2002-05-01 | Euro Celtique Sa | Pharmaceutical combination |
| US7842808B2 (en) * | 2002-06-05 | 2010-11-30 | Bristol-Myers Squibb Company | Anti-migraine spirocycles |
| US7220862B2 (en) * | 2002-06-05 | 2007-05-22 | Bristol-Myers Squibb Company | Calcitonin gene related peptide receptor antagonists |
| US6864271B2 (en) | 2002-11-12 | 2005-03-08 | The Foundation For The Lsu Health Sciences Center | Synergistic combinations including N-acylated 4-hydroxyphenylamine derivatives |
| AU2003296954A1 (en) * | 2002-12-13 | 2004-07-09 | The Regents Of The University Of California | Analgesic combination comprising nalbuphine |
| EP2218448B1 (en) | 2002-12-13 | 2015-09-23 | Durect Corporation | Oral drug delivery system comprising high viscosity liquid carrier materials |
| GB0300531D0 (en) | 2003-01-10 | 2003-02-12 | West Pharm Serv Drug Res Ltd | Pharmaceutical compositions |
| US20040157784A1 (en) * | 2003-02-10 | 2004-08-12 | Jame Fine Chemicals, Inc. | Opiod tannate compositions |
| HUP0300929A3 (en) * | 2003-04-09 | 2005-06-28 | Richter Gedeon Vegyeszet | Analgetic and/or muscle relaxant pharmaceutical composition |
| US20040213828A1 (en) * | 2003-04-23 | 2004-10-28 | Smith David J. | Pain relief lollipop compositions and methods |
| US20040259809A1 (en) * | 2003-06-17 | 2004-12-23 | Pediamed Pharmaceuticals, Inc. | Pharmaceutical compositions including an antihistamine and a stimulant and method of use thereof |
| US9492541B2 (en) * | 2004-09-14 | 2016-11-15 | Sovereign Pharmaceuticals, Llc | Phenylepherine containing dosage form |
| US20050203115A1 (en) * | 2004-03-10 | 2005-09-15 | Sancilio Frederick D. | Narcotic-NSAID ion pairs |
| US7404970B2 (en) * | 2004-04-13 | 2008-07-29 | Konec, Inc. | Pain relief composition, method to form same, and method to use same |
| EP1817023A4 (en) * | 2004-11-16 | 2010-08-18 | Limerick Biopharma Inc | METHODS AND COMPOSITIONS FOR TREATING PAIN |
| US20070087977A1 (en) * | 2004-11-16 | 2007-04-19 | Wendye Robbins | Methods and compositions for treating pain |
| US20060223786A1 (en) * | 2005-04-01 | 2006-10-05 | Smith David J | Transdermal pain control method and device |
| AU2007225022A1 (en) * | 2006-03-15 | 2007-09-20 | Biotech Pharmaceuticals Pty Ltd | Non-codeine opioid analgesic process and formulations |
| US20070248657A1 (en) * | 2006-04-25 | 2007-10-25 | Smith David J | Multi-compartment transdermal pain control device |
| US8034801B2 (en) | 2006-07-12 | 2011-10-11 | Aska Pharmaceutical Co., Ltd. | Analgesic agent |
| US8653066B2 (en) | 2006-10-09 | 2014-02-18 | Charleston Laboratories, Inc. | Pharmaceutical compositions |
| KR20100045983A (ko) | 2007-06-29 | 2010-05-04 | 에모리 유니버시티 | 신경보호를 위한 nmda 수용체 길항물질 |
| US20090110724A1 (en) * | 2007-10-31 | 2009-04-30 | Everett Laboratories, Inc. | Compositions and methods for treatment of pain |
| EP2067471B1 (en) | 2007-12-06 | 2018-02-14 | Durect Corporation | Oral pharmaceutical dosage forms |
| EP2240022B1 (en) | 2008-01-09 | 2016-12-28 | Charleston Laboratories, Inc. | Bilayered tablets comprising oxycodone and promethazine |
| US20090191257A1 (en) * | 2008-01-29 | 2009-07-30 | Innovative Pharmaceuticals, Llc | Pain relief lollipop compositions and methods |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| US20100221313A1 (en) * | 2008-12-01 | 2010-09-02 | Innovative Pharmaceuticals, Llc | Transdermal reservoir patch |
| AU2010224063B2 (en) * | 2009-03-12 | 2015-04-16 | Cumberland Pharmaceuticals Inc | Administration of intravenous ibuprofen |
| EP2451274B1 (en) | 2009-07-08 | 2017-10-04 | Charleston Laboratories, Inc. | Pharmaceutical compositions |
| US8871810B2 (en) | 2009-07-15 | 2014-10-28 | Cumberland Pharmaceuticals Inc. | Treating critically ill patients with intravenous ibuprofen |
| WO2013070617A1 (en) | 2011-11-07 | 2013-05-16 | Nektar Therapeutics | Compositions, dosage forms, and coadministration of an opioid agonist compound and an analgesic compound |
| US10525054B2 (en) | 2011-11-07 | 2020-01-07 | Inheris Biopharma, Inc. | Compositions, dosage forms, and co-administration of an opioid agonist compound and an analgesic compound |
| US9072710B2 (en) | 2012-03-16 | 2015-07-07 | Cumberland Pharmaceuticals Inc. | Injectable ibuprofen formulation |
| CA2905131A1 (en) | 2013-03-15 | 2014-09-18 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
| CA3042642A1 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| EA201990684A1 (ru) | 2013-12-24 | 2020-12-30 | Вирджиния Коммонвелт Юниверсити | Способы применения оксигенированных холестеролсульфатов (ocs) |
| CA3164826C (en) * | 2014-06-20 | 2026-03-17 | Lohocla Research Corporation | Multifunctional aminoquinoline therapeutic agents |
| DK3169315T3 (da) | 2014-07-17 | 2020-08-10 | Pharmaceutical Manufacturing Res Services In | Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse |
| AU2015336065A1 (en) | 2014-10-20 | 2017-05-04 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| US10179109B2 (en) | 2016-03-04 | 2019-01-15 | Charleston Laboratories, Inc. | Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates |
| CN109475505A (zh) | 2016-07-06 | 2019-03-15 | 度瑞公司 | 具有药物组成物、屏障层及药物层的口服剂型 |
| AU2017364077A1 (en) | 2016-11-22 | 2019-06-20 | Elektrofi, Inc. | Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof |
| US11214544B2 (en) | 2017-04-14 | 2022-01-04 | Kempharm, Inc. | Dextrorphan prodrugs and processes for making and using them |
| WO2019023392A1 (en) | 2017-07-25 | 2019-01-31 | Elektrofi, Inc. | FORMATION OF PARTICLES COMPRISING AGENTS |
| WO2019226969A1 (en) | 2018-05-24 | 2019-11-28 | Elektrofi, Inc. | Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof |
| AU2020214626B2 (en) | 2019-01-31 | 2025-10-16 | Halozyme Hypercon, Inc. | Particle formation and morphology |
| AU2020344675B2 (en) | 2019-09-13 | 2026-06-25 | Halozyme Hypercon, Inc. | Compositions and methods for the delivery of therapeutic biologics for treatment of disease |
| US12377050B2 (en) | 2020-04-17 | 2025-08-05 | Elektrofi, Inc. | Methods of forming particles by continuous droplet formation and dehydration |
| US11382873B1 (en) * | 2021-01-08 | 2022-07-12 | Vitalis Analgesics LLC | Oral administration of ketamine |
| US11977085B1 (en) | 2023-09-05 | 2024-05-07 | Elan Ehrlich | Date rape drug detection device and method of using same |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4316888A (en) * | 1980-04-15 | 1982-02-23 | Nelson Research & Development Co. | Method and composition of reducing pain |
| US4446140A (en) * | 1981-12-10 | 1984-05-01 | Nelson Research & Development Company | Method and composition for treating mouth pain |
| CA1194799A (en) * | 1981-12-10 | 1985-10-08 | Eric L. Nelson | Method and composition for reducing menstrual pain |
| US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
| ZA861211B (en) * | 1985-02-25 | 1987-10-28 | Lilly Co Eli | Analgesic composition |
| US4994467A (en) * | 1989-05-31 | 1991-02-19 | Zimmerman Andrew W | Treating autism and other developmental disorders in children with NMDA receptor antagonists |
| US5013540A (en) * | 1989-11-30 | 1991-05-07 | Board Of Regents, The University Of Texas System | Using NMDA receptor antagonists to reduce damage due to laser treatment |
| US5164398A (en) * | 1991-04-01 | 1992-11-17 | Merck & Co., Inc. | Ibuprofen-antitussive combinations |
| DE122004000032I2 (de) * | 1991-09-06 | 2006-02-09 | Mcneilab Inc | Zusammensetzung die eine Tramadol-Verbindung und Acetaminophen enth{lt, und ihre Verwendung |
| WO1993017673A1 (en) * | 1992-03-03 | 1993-09-16 | Top Gold Pty., Limited | Sustained release analgesics |
| US5348747A (en) * | 1992-03-05 | 1994-09-20 | American Home Products Corporation | Pharmaceutical coating sugars |
| US5321012A (en) * | 1993-01-28 | 1994-06-14 | Virginia Commonwealth University Medical College | Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance |
| CA2115792C (en) * | 1993-03-05 | 2005-11-01 | David J. Mayer | Method for the treatment of pain |
| MX9701477A (es) * | 1994-09-02 | 1998-02-28 | Univ Virginia Commonwealth | Composicion para aliviar el dolor, que contiene un analgesico no narcotico y un mejorador de analgesia. |
-
1995
- 1995-08-02 US US08/510,546 patent/US5840731A/en not_active Expired - Fee Related
-
1996
- 1996-07-31 PT PT96926846T patent/PT845989E/pt unknown
- 1996-07-31 JP JP50789697A patent/JP3924321B2/ja not_active Expired - Fee Related
- 1996-07-31 AT AT96926846T patent/ATE214277T1/de not_active IP Right Cessation
- 1996-07-31 DK DK96926846T patent/DK0845989T3/da active
- 1996-07-31 ES ES96926846T patent/ES2170865T3/es not_active Expired - Lifetime
- 1996-07-31 CA CA002228249A patent/CA2228249C/en not_active Expired - Fee Related
- 1996-07-31 DE DE69619832T patent/DE69619832T2/de not_active Expired - Fee Related
- 1996-07-31 WO PCT/US1996/012597 patent/WO1997004780A2/en not_active Ceased
- 1996-07-31 EP EP96926846A patent/EP0845989B1/en not_active Expired - Lifetime
- 1996-07-31 AU AU66865/96A patent/AU6686596A/en not_active Abandoned
-
1997
- 1997-07-07 US US08/888,728 patent/US5869498A/en not_active Expired - Fee Related
- 1997-07-07 US US08/889,041 patent/US5863922A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5869498A (en) | 1999-02-09 |
| AU6686596A (en) | 1997-02-26 |
| US5863922A (en) | 1999-01-26 |
| JPH11512081A (ja) | 1999-10-19 |
| EP0845989B1 (en) | 2002-03-13 |
| WO1997004780A2 (en) | 1997-02-13 |
| US5840731A (en) | 1998-11-24 |
| DE69619832T2 (de) | 2002-10-31 |
| CA2228249C (en) | 2002-12-03 |
| DK0845989T3 (da) | 2002-04-29 |
| CA2228249A1 (en) | 1997-02-13 |
| ATE214277T1 (de) | 2002-03-15 |
| PT845989E (pt) | 2002-07-31 |
| EP0845989A2 (en) | 1998-06-10 |
| JP3924321B2 (ja) | 2007-06-06 |
| DE69619832D1 (de) | 2002-04-18 |
| WO1997004780A3 (en) | 1997-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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