ES2171533T3 - Composiciones que contienen nebivolol micronizado. - Google Patents

Composiciones que contienen nebivolol micronizado.

Info

Publication number
ES2171533T3
ES2171533T3 ES95908927T ES95908927T ES2171533T3 ES 2171533 T3 ES2171533 T3 ES 2171533T3 ES 95908927 T ES95908927 T ES 95908927T ES 95908927 T ES95908927 T ES 95908927T ES 2171533 T3 ES2171533 T3 ES 2171533T3
Authority
ES
Spain
Prior art keywords
compositions containing
containing micronized
nebivolol
micronized nebivolol
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95908927T
Other languages
English (en)
Inventor
Eugeen Jans
Guido Franciscus Smans
Paul Marie Victor Gilis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22731545&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2171533(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of ES2171533T3 publication Critical patent/ES2171533T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Dental Preparations (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPOSICIONES FARMACEUTICAS QUE CONTIENEN NEBIVOLOL DE FORMULA (I) MICRONIZADO COMO PRINCIPIO ACTIVO Y A LA FORMA DE PREPARAR ESTAS COMPOSICIONES.
ES95908927T 1994-02-17 1995-02-10 Composiciones que contienen nebivolol micronizado. Expired - Lifetime ES2171533T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19798894A 1994-02-17 1994-02-17

Publications (1)

Publication Number Publication Date
ES2171533T3 true ES2171533T3 (es) 2002-09-16

Family

ID=22731545

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95908927T Expired - Lifetime ES2171533T3 (es) 1994-02-17 1995-02-10 Composiciones que contienen nebivolol micronizado.

Country Status (30)

Country Link
US (1) US5759580A (es)
EP (1) EP0744946B1 (es)
JP (1) JP3810079B2 (es)
KR (1) KR100361636B1 (es)
CN (1) CN1112921C (es)
AT (1) ATE212547T1 (es)
AU (1) AU688860B2 (es)
BR (1) BR9506828A (es)
CA (1) CA2182582C (es)
CY (1) CY2329B1 (es)
CZ (1) CZ290844B6 (es)
DE (1) DE69525241T2 (es)
DK (1) DK0744946T3 (es)
ES (1) ES2171533T3 (es)
FI (1) FI117888B (es)
HU (1) HU221848B1 (es)
IL (1) IL112659A (es)
MX (1) MX9603314A (es)
MY (1) MY115339A (es)
NO (1) NO314712B1 (es)
NZ (1) NZ279822A (es)
PL (1) PL178505B1 (es)
PT (1) PT744946E (es)
RU (1) RU2137473C1 (es)
SG (1) SG47487A1 (es)
SI (1) SI0744946T1 (es)
SK (1) SK283250B6 (es)
TW (1) TW355683B (es)
WO (1) WO1995022325A1 (es)
ZA (1) ZA951294B (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK282144B6 (sk) * 1994-12-28 2001-11-06 Janssen Pharmaceutica N. V. Liečivo na terapeutické a profylaktické ošetrenie degeneratívnych chorôb vaskulárneho systému a nervovej sústavy, ktoré súvisia s oxidačným stresom
HU228350B1 (hu) 1995-12-27 2013-03-28 Tibotec Pharm Ltd Bioadhezív, szilárd gyógyszeradagolási forma
DE19637082A1 (de) * 1996-09-12 1998-03-19 Boehringer Mannheim Gmbh Schnellzerfallende Pellets
AU3176097A (en) * 1997-06-13 1998-12-30 Medinova Medical Consulting Gmbh Drug targeting system, method of its preparation and its use
AR017512A1 (es) * 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
AR016827A1 (es) 1997-08-22 2001-08-01 Smithkline Beecham Corp PROCEDIMIENTO PARA LA PREPARACIoN DE UNA TABLETA FARMACÉUTICA
US20030152636A1 (en) * 2000-02-23 2003-08-14 Nanopharm Ag Method of treating cancer
US6531158B1 (en) * 2000-08-09 2003-03-11 Impax Laboratories, Inc. Drug delivery system for enhanced bioavailability of hydrophobic active ingredients
CA2446064A1 (en) * 2001-05-02 2002-11-07 Nitromed, Inc. Nitrosated and nitrosylated nebivolol and its metabolites, compositions and methods of use
RU2214234C1 (ru) * 2002-11-25 2003-10-20 Нестерук Владимир Викторович ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ОБЛАДАЮЩАЯ СВОЙСТВАМИ КАРДИОСЕЛЕКТИВНОГО β1-АДРЕНОБЛОКАТОРА
RU2286779C2 (ru) * 2003-02-06 2006-11-10 Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" Лекарственная форма, обладающая диуретическим и антигипертензивным действием, и способ ее изготовления
US7803838B2 (en) * 2004-06-04 2010-09-28 Forest Laboratories Holdings Limited Compositions comprising nebivolol
CN101862322A (zh) 2004-07-30 2010-10-20 托伦特药物有限公司 奈必洛尔及其药学可接受盐、制备方法以及奈必洛尔的药物组合物
ES2341250T3 (es) * 2004-08-11 2010-06-17 Hetero Drugs Limited Procedimiento novedoso de preparacion de intermediarios de nebivolol.
US7344907B2 (en) * 2004-11-19 2008-03-18 International Business Machines Corporation Apparatus and methods for encapsulating microelectromechanical (MEM) devices on a wafer scale
WO2006083779A2 (en) * 2005-01-31 2006-08-10 Mylan Laboratories, Inc. Pharmaceutical composition comprising hydroxylated nebivolol
WO2006084684A1 (de) * 2005-02-11 2006-08-17 Stada Arzneimittel Ag Pharmazeutische zusammensetzungen nebivolo und ein hydrophiles polymer
EP1803716B1 (en) * 2005-12-28 2012-07-25 Acino Pharma AG A process for preparation of racemic nebivolol
US7560575B2 (en) 2005-12-28 2009-07-14 Acino Pharma Ag Process for preparation of racemic Nebivolol
US7858812B2 (en) * 2006-01-18 2010-12-28 Hetero Drugs Limited Process for isolation of desired isomers of nebivolol intermediates
EP1839658A1 (en) * 2006-03-30 2007-10-03 Hexal A/S Pharmaceutical composition comprising micronized nebivolol
EP1886674B1 (de) * 2006-08-04 2010-03-31 Alfred, E. Tiefenbacher Gmbh & Co. Kg Pharmazeutische Zusammensetzung enthaltend Nebivolol
DE102006036579A1 (de) * 2006-08-04 2008-02-07 Alfred E. Tiefenbacher Gmbh & Co.Kg Pharmazeutische Zusammensetzung
UA97813C2 (uk) * 2006-12-05 2012-03-26 Янссен Фармацевтика Н.В. Фумаратна сіль (альфа s, бета r)-6-бром-альфа-[2-(диметиламіно)етил]-2-метоксі-альфа-1-нафталеніл-бета-феніл-3-хінолінетанолу
WO2008089549A1 (en) * 2007-01-22 2008-07-31 Genpharm Ulc Pharmaceutical compositions comprising nebivolol or a nebivolol analogue
WO2009004649A2 (en) * 2007-05-21 2009-01-08 Sun Pharmaceutical Industries Limited Enteric coated pharmaceutical compositions
US20090030071A1 (en) * 2007-07-26 2009-01-29 Shaw Andrew A Treatment of Cardiovascular Disease in Mexican Americans Using Nebivolol
CN101463024B (zh) 2007-12-21 2011-06-08 上海现代制药股份有限公司 一种制备rrrs和sssr型的奈必洛尔中间体混合物的方法
US20090181975A1 (en) * 2008-01-15 2009-07-16 Forest Laboratories Holdings Limited Nebivolol in the treatment of sexual dysfunction
EP2163551B1 (en) 2008-09-08 2011-11-16 Cadila Pharmaceuticals Ltd. An improved process for the preparation of nebivolol hydrochloride
IT1395354B1 (it) 2009-07-23 2012-09-14 Zach System Spa Processo di preparazione di nebivololo
IT1397962B1 (it) 2010-02-11 2013-02-04 Menarini Int Operations Lu Sa Processo per la preparazione del nebivololo.
KR20110130872A (ko) * 2010-05-28 2011-12-06 현대약품 주식회사 결정형 염산 네비볼롤을 포함하는 약학 조성물 및 제조방법
US20120003304A1 (en) * 2010-07-02 2012-01-05 Fmc Corporation Solid Forms
CN105085499B (zh) * 2015-08-07 2018-09-25 上海现代制药海门有限公司 盐酸奈必洛尔中间体混合物的结晶分离方法
KR20190140011A (ko) * 2017-04-28 2019-12-18 아사나 바이오사이언시스 엘엘씨 아토피성 피부염을 치료하고, 활성 약학적 성분의 안정성을 개선하기 위한 제형물, 방법, 키트, 및 투여형
US12576026B2 (en) * 2020-07-08 2026-03-17 Extrovis Ag Formulations of nebivolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60107106A (ja) * 1983-11-15 1985-06-12 Mitsubishi Electric Corp 曲線補間装置
CA1337429C (en) * 1983-12-05 1995-10-24 Guy Rosalia Eugene Van Lommen Derivatives of 2,2'-iminobisethanol
CA1337432C (en) * 1988-03-23 1995-10-24 Raymond M. Xhonneux Method of lowering the blood pressure
JPH02264744A (ja) * 1989-04-04 1990-10-29 Kyowa Hakko Kogyo Co Ltd 光学活性なｐ―フルオロフェノキシ誘導体およびその製造法

Also Published As

Publication number Publication date
CZ290844B6 (cs) 2002-10-16
IL112659A (en) 1999-06-20
SK105896A3 (en) 1997-05-07
NO314712B1 (no) 2003-05-12
DE69525241D1 (de) 2002-03-14
MY115339A (en) 2003-05-31
EP0744946B1 (en) 2002-01-30
CZ234696A3 (en) 1996-11-13
CA2182582C (en) 2005-03-29
KR100361636B1 (ko) 2003-02-11
PL178505B1 (pl) 2000-05-31
EP0744946A1 (en) 1996-12-04
US5759580A (en) 1998-06-02
CN1140991A (zh) 1997-01-22
NO963439L (no) 1996-08-16
PT744946E (pt) 2002-07-31
TW355683B (en) 1999-04-11
WO1995022325A1 (en) 1995-08-24
FI963227A0 (fi) 1996-08-16
BR9506828A (pt) 1997-09-30
ZA951294B (en) 1996-08-16
CN1112921C (zh) 2003-07-02
AU688860B2 (en) 1998-03-19
SG47487A1 (en) 1998-04-17
IL112659A0 (en) 1995-05-26
CA2182582A1 (en) 1995-08-24
JPH09508913A (ja) 1997-09-09
HU221848B1 (hu) 2003-02-28
DK0744946T3 (da) 2002-05-06
DE69525241T2 (de) 2002-08-29
RU2137473C1 (ru) 1999-09-20
FI117888B (fi) 2007-04-13
NZ279822A (en) 1997-04-24
SK283250B6 (sk) 2003-04-01
PL315973A1 (en) 1996-12-23
JP3810079B2 (ja) 2006-08-16
MX9603314A (es) 1997-02-28
HU9602272D0 (en) 1996-10-28
AU1706895A (en) 1995-09-04
SI0744946T1 (en) 2002-06-30
CY2329B1 (en) 2004-02-06
ATE212547T1 (de) 2002-02-15
HUT75332A (en) 1997-05-28
FI963227L (fi) 1996-08-16

Similar Documents

Publication Publication Date Title
ES2171533T3 (es) Composiciones que contienen nebivolol micronizado.
HN2002000247A (es) Derivados de sulfonamida
ES2169147T3 (es) Derivados de beta-carbolina agonistas de la melatonina, sus procedimientos de preparacion y su utilizacion a titulo de medicamento.
MX9202328A (es) Composicion farmaceutica local que contiene un compuesto alilamina como el agente activo.
MXPA05001061A (es) Composiciones farmaceuticas, acuosas de 2,6-diisopropilfenol.
ES2140961T3 (es) Nuevos derivados de 19-nor-pregneno.
ES2181882T3 (es) Sulfonamidas inhibidoras de la aspartil-proteasa que contienen tetrahidrofurano (thf).
ES2147739T3 (es) Fosfonooximetil-eteres de derivados de taxano.
HN1999000089A (es) Formulaciones de ziprasidona
BR0111206A (pt) Derivados de arilmetilamina para uso como inibidores de triptase
MXPA02011844A (es) Compuestos con un grupo de sulfonamida, y composiciones farmaceuticas que contienen estos compuestos.
BR0113661A (pt) Composições farmacêuticas para a liberação tópica de inibidores da enzima ciclooxigenase-2
PA8469401A1 (es) Derivados biciclicos del acido hidroxamico
BR0001468A (pt) ácidos dioxiciclopentil hidroxânicos
MX9300498A (es) Derivados de n-sulfonil-2-oxo-indol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
BR0214343A (pt) Inibidores de 11 - beta - hidroxi esteróide desidrogenase tipo 1
ES2142798T3 (es) Derivados de 3-amido pirazol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
HN2002000300A (es) Nuevos derivados de piperazina
PA8487701A1 (es) Derivados de 3,3-biarilpiperidina y 2,2-biarilmorfolina
GT200000001A (es) Derivados de eter propargilico novedosos.
BR0111678A (pt) Composições medicinais contendo derivados de propenona
ES2126114T3 (es) Composiciones liquidas estables de interferon gamma.
PT1105114E (pt) Composicoes farmaceuticas topicas contendo nimesulide
HN2001000235A (es) Derivados puentes de piperazina
CR7956A (es) Oxazolidinonas de indolona antibacterial intermedios para su preparacion y composiciones farmaceuticas que contienen los mismos

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 744946

Country of ref document: ES