ES2172692T3 - Procedimiento para la obtencion de aminas opticamente activas. - Google Patents

Procedimiento para la obtencion de aminas opticamente activas.

Info

Publication number
ES2172692T3
ES2172692T3 ES96939915T ES96939915T ES2172692T3 ES 2172692 T3 ES2172692 T3 ES 2172692T3 ES 96939915 T ES96939915 T ES 96939915T ES 96939915 T ES96939915 T ES 96939915T ES 2172692 T3 ES2172692 T3 ES 2172692T3
Authority
ES
Spain
Prior art keywords
procedure
formula
aminas
optically active
amines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96939915T
Other languages
English (en)
Inventor
Uwe Stelzer
Claus Dreisbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26020985&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2172692(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE19637336A external-priority patent/DE19637336A1/de
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2172692T3 publication Critical patent/ES2172692T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION TRATA DE UN PROCEDIMIENTO PARA LA PREPARACION DE AMINAS OPTICAMENTE ACTIVAS DE FORMULA (I*), EN LA CUAL R Y M TIENE LA SIGNIFICACION DADA EN LA DESCRIPCION. EN ESTE PROCEDIMIENTO, LA PREPARACION DE DICHAS AMINAS SE LLEVA A CABO DE MANERA QUE (A) EN UN PRIMER PASO SE HACEN REACCIONAR LAS AMINAS RACEMICAS DE FORMULA (I) EN PRESENCIA DE LIPASAS DE CANDIDA ANTARCTICA Y, OPCIONALMENTE, EN PRESENCIA DE UN DISOLVENTE, CON ESTERES DE FORMULA (II), EN LA CUAL R 1 , R 2 , X Y N TIENEN LA SIGNIFICACION DADA EN LA DESCRIPCION; (B) EN UN SEGUNDO PASO SE SEPARA LA MEZCLA RESULTANTE DE LAS (S) AMINAS DE FORMULA (I S) Y LAS (R) - AMINAS ACILADAS DE FORMULA (III).
ES96939915T 1995-12-06 1996-11-25 Procedimiento para la obtencion de aminas opticamente activas. Expired - Lifetime ES2172692T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19545466 1995-12-06
DE19637336A DE19637336A1 (de) 1995-12-06 1996-09-13 Verfahren zur Herstellung von optisch aktiven Aminen

Publications (1)

Publication Number Publication Date
ES2172692T3 true ES2172692T3 (es) 2002-10-01

Family

ID=26020985

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96939915T Expired - Lifetime ES2172692T3 (es) 1995-12-06 1996-11-25 Procedimiento para la obtencion de aminas opticamente activas.

Country Status (7)

Country Link
US (1) US6387692B1 (es)
EP (1) EP0865500B1 (es)
JP (2) JP3714964B2 (es)
AU (1) AU2838397A (es)
DE (1) DE59608741D1 (es)
ES (1) ES2172692T3 (es)
WO (1) WO1997020946A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19956786A1 (de) 1999-11-25 2001-05-31 Basf Ag Verfahren zur Herstellung optisch aktiver Amine
KR100423875B1 (ko) * 2001-12-06 2004-03-22 주식회사 포스코 키랄 아민의 제조 방법
DE102005028492A1 (de) * 2005-06-20 2006-12-28 Basf Ag Verfahren zur Herstellung von optisch aktiven Aminoalkylphenolen
JP5329973B2 (ja) * 2005-12-28 2013-10-30 ビーエーエスエフ ソシエタス・ヨーロピア リパーゼ触媒を用いるエナンチオ選択的アシル化とその後の硫酸による沈殿によって、ラセミ体の４−（１−アミノエチル）安息香酸メチルエステルから（ｒ）−および（ｓ）−４−（１−アンモニウムエチル）安息香酸メチルエステル硫酸塩を調製する方法
DE102006028818A1 (de) * 2006-06-21 2007-12-27 Evonik Degussa Gmbh Verfahren zur Herstellung enantiomerenangereicherter Amine und Amide durch enzymatische Racematspaltung
JP2010222262A (ja) * 2009-03-19 2010-10-07 Idemitsu Kosan Co Ltd アルコキシｎ，ｎ−ジアルキル酢酸アミドの製造方法、及びポリマー溶液

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4332738A1 (de) * 1993-09-25 1995-03-30 Basf Ag Racematspaltung primärer und sekundärer Amine durch Enzym-katalysierte Acylierung
DE19523151A1 (de) 1995-02-03 1996-08-14 Basf Ag Racematspaltung primärer und sekundärer heteroatomsubstituierter Amine durch Enzym-katalysierte Acylierung
CN1087348C (zh) * 1995-02-03 2002-07-10 巴斯福股份公司 通过酶催化酰化拆分杂原子取代的伯胺和仲胺的外消旋体
DE19534208A1 (de) * 1995-09-15 1997-03-20 Basf Ag Spaltung von optisch aktiven Amiden
DE19621686A1 (de) * 1996-05-30 1997-12-04 Bayer Ag Verfahren zur Herstellung von optisch aktiven Aminen

Also Published As

Publication number Publication date
EP0865500A1 (de) 1998-09-23
DE59608741D1 (de) 2002-03-21
EP0865500B1 (de) 2002-02-13
JP2000501292A (ja) 2000-02-08
US6387692B1 (en) 2002-05-14
JP2005053933A (ja) 2005-03-03
AU2838397A (en) 1997-06-27
WO1997020946A1 (de) 1997-06-12
JP3714964B2 (ja) 2005-11-09

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