ES2173044B1 - Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones. - Google Patents

Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones.

Info

Publication number
ES2173044B1
ES2173044B1 ES200100577A ES200100577A ES2173044B1 ES 2173044 B1 ES2173044 B1 ES 2173044B1 ES 200100577 A ES200100577 A ES 200100577A ES 200100577 A ES200100577 A ES 200100577A ES 2173044 B1 ES2173044 B1 ES 2173044B1
Authority
ES
Spain
Prior art keywords
glycine
nitrosotio
valil
glutamil
gamma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES200100577A
Other languages
English (en)
Other versions
ES2173044A1 (es
Inventor
Moliner Jose Repolles
Perez-Rasilla Eduardo Salas
Coy Francisco Pubill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lacer SA
Original Assignee
Lacer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lacer SA filed Critical Lacer SA
Priority to ES200100577A priority Critical patent/ES2173044B1/es
Priority to PCT/EP2002/002598 priority patent/WO2002085847A2/en
Priority to AU2002310939A priority patent/AU2002310939A1/en
Priority to PE2002000189A priority patent/PE20021040A1/es
Priority to PA20028541201A priority patent/PA8541201A1/es
Publication of ES2173044A1 publication Critical patent/ES2173044A1/es
Application granted granted Critical
Publication of ES2173044B1 publication Critical patent/ES2173044B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a glicina, N-[N-L-{ga}-glutamil- 3-(nitrosotio)-L-valil] de la siguiente fórmula (I): **FIGURA1** y a sus sales fisiológicamente aceptables, así como a productos farmacéuticos que contienen uno o varios de estos compuestos, a los métodos de tratamiento y prevención de enfermedades, inclusive la administración de una cantidad eficaz de uno o varios de dichos compuestos y a la utilización de uno o varios de dichos compuestos para la producción de un medicamento para el tratamiento y la prevención de enfermedades.
ES200100577A 2001-03-13 2001-03-13 Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones. Expired - Fee Related ES2173044B1 (es)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES200100577A ES2173044B1 (es) 2001-03-13 2001-03-13 Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones.
PCT/EP2002/002598 WO2002085847A2 (en) 2001-03-13 2002-03-08 Glycine, n-[n-l-gamma-glutamyl-3-(nitrosothio)-l-valyl] and use thereof
AU2002310939A AU2002310939A1 (en) 2001-03-13 2002-03-08 Glycine, n-(n-l-gamma-glutamyl-3-(nitrosothio)-l-valyl) and use thereof
PE2002000189A PE20021040A1 (es) 2001-03-13 2002-03-11 GLICINA, N-[N-L-g-GLUTAMIL-3-(NITROSOTIO)-L-VALIL] Y SUS APLICACIONES
PA20028541201A PA8541201A1 (es) 2001-03-13 2002-03-12 Glicina, n-[n-l-gamma-glutamil-3-(nitrosotio)-l-valil] y sus aplicaciones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200100577A ES2173044B1 (es) 2001-03-13 2001-03-13 Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones.

Publications (2)

Publication Number Publication Date
ES2173044A1 ES2173044A1 (es) 2002-10-01
ES2173044B1 true ES2173044B1 (es) 2004-01-16

Family

ID=8497059

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200100577A Expired - Fee Related ES2173044B1 (es) 2001-03-13 2001-03-13 Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones.

Country Status (5)

Country Link
AU (1) AU2002310939A1 (es)
ES (1) ES2173044B1 (es)
PA (1) PA8541201A1 (es)
PE (1) PE20021040A1 (es)
WO (1) WO2002085847A2 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0412699B1 (en) * 1989-08-07 1994-04-27 Takeda Chemical Industries, Ltd. Nitrosothiol derivatives, their production and use
ES2147162B1 (es) * 1999-01-27 2001-03-16 Lacer Sa "s-nitrosotioles como agentes para el tratamiento de disfunciones circulatorias".

Also Published As

Publication number Publication date
ES2173044A1 (es) 2002-10-01
WO2002085847A2 (en) 2002-10-31
PE20021040A1 (es) 2002-11-19
AU2002310939A1 (en) 2002-11-05
PA8541201A1 (es) 2003-02-28
WO2002085847A3 (en) 2003-10-30

Similar Documents

Publication Publication Date Title
CY1123260T1 (el) Ενα αλας νατριου του ν-((1,2,3,5,6,7-eξaϋδpo-s-inδaken-4-υλ)καρβαμοϋλ)-1-ισοπροπυλ-1η-πυραζολο-3-σουλφοναμιδιου
JOP20200154B1 (ar) مركبات ومشتقات بيريدو بيريمينون بها استبدال ببنزيل أمينو جديدة كمثبطات sos1
EA200300776A1 (ru) Производные фенэтаноламина для лечения респираторных заболеваний
PA8547701A1 (es) Nucleosidos 4 substituidos.
CY1109422T1 (el) Παραγωγα φαιναιθανολαμινης για θεραπεια ασθενειων του αναπνευστικου
DE60315492D1 (de) Medizinisch verwendbare arylethanolamin verbindungen
ATE381535T1 (de) Phenethanolaminderivate
BR0312729A (pt) Novos derivados de indol-3-enxofre
DE50311898D1 (de) Fredericamycin-derivate als arzneimittel zur tumorbehandlung
ATE381537T1 (de) Formanilid-derivative als beta2-adrenorezeptor- agonisten
UA107578C2 (uk) Комбінована терапія при лікуванні діабету
EA201400365A1 (ru) Новые тиопроизводные лактамов в качестве высокоактивных ингибиторов hdac и их применение в качестве лекарственных средств
DE60334773D1 (de) Formulierungen zur oralen verabreichung von wirkstoffen
ECSP045441A (es) Nueva sal de perindopril y composiciones farmacéuticas que lo contienen
NZ766762A (en) Modified lipidated relaxin b chain peptides and their therapeutic use
AR013079A1 (es) Derivados sustituidos de tetrahidrofurano-3-onas, de tetrahidropirano-3- onas y tetrahidrotiofen-3-onas, un procedimiento para su preparacion unacomposicion farmaceutica de un medicamento util como inhibidores de proteasas e intermediarios
ECSP045493A (es) Nuevas composiciones farmacéuticas que contienen flibanserina polimorfo a
NO20084478L (no) Konjugerte lipidderivater
MX2025012370A (es) Compuesto de amida, composicion farmaceutica que comprende el compuesto y uso de esta
BRPI0410044A (pt) forma de dosagem contendo pantoprazol como ingrediente ativo
AR040441A1 (es) Compuesto de tiol, composicion farmaceutica que lo comprende, su uso para la fabricacion de un medicamento, procedimiento para prepararlo y compuesto intermediario de utilidad en dicho procedimiento
HUP0101224A2 (hu) Neuraminidáz inhibitor hatású pirrolidinszármazékok és ezeket a vegyületeket tartalmazó gyógyászati készítmények
ATE400563T1 (de) Neue neurokinin-antagonisten zum gebrauch als arzneimittel
EA200400707A1 (ru) Ингибиторы 11-бета-гидроксистероиддегидрогеназы типа 1
EA200701615A1 (ru) Новые лекарственные средства для лечения заболеваний дыхательных путей

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 20021001

Kind code of ref document: A1

Effective date: 20021001

FG2A Definitive protection

Ref document number: 2173044B1

Country of ref document: ES

FD2A Announcement of lapse in spain

Effective date: 20180807