ES2174864T3 - Nuevos tratamientos que utilizan derivados de fenetilo. - Google Patents

Nuevos tratamientos que utilizan derivados de fenetilo.

Info

Publication number
ES2174864T3
ES2174864T3 ES94304252T ES94304252T ES2174864T3 ES 2174864 T3 ES2174864 T3 ES 2174864T3 ES 94304252 T ES94304252 T ES 94304252T ES 94304252 T ES94304252 T ES 94304252T ES 2174864 T3 ES2174864 T3 ES 2174864T3
Authority
ES
Spain
Prior art keywords
rent
hydrogen
amino
compound
fenetile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94304252T
Other languages
English (en)
Inventor
Richard Leslie Rudolph
Albert Thomas Derivan
Eric Anthony Muth
Gertrude Virginia Upton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22181084&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2174864(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth LLC filed Critical Wyeth LLC
Application granted granted Critical
Publication of ES2174864T3 publication Critical patent/ES2174864T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

LA INVENCION SUMINISTRA EL USO DE UN COMPUESTO PARA PREPARAR UN MEDICAMENTO PARA TRATAR LA OBESIDAD, LAS ENFERMEDADES DE ANSIEDAD GENERALIZADA, LAS ENFERMEDADES DE ESTRES POSTRAUMATICOS, LOS DESORDENES DISFORICOS DE LA ULTIMA FASE LUTEAL (SINDROME PREMESTRUAL), DESORDENES DE FALTA DE ATENCION, CON O SIN HIPERACTIVIDAD, EL SINDROME DE GILLES DE LA TOURETTE, LA BULIMIA NERVIOSA O EL SINDROME DE SHY DRAGER. EL COMPUESTO ES UN AMINO DE HIDROXICICLOALCANOFENOETIL DE LA SIGUIENTE FORMULA ESTRUCTURAL: EN LA CUAL A ES UNA MOLECULA DE LA FORMULA: EN LA QUE LA LINEA PUNTEADA REPRESENTA UNA INSATURACION OPCIONAL; R1 ES HIDROGENO O ALQUIL; R2 ES ALQUIL; R4 ES HIDROGENO, ALQUIL, FORMIL O ALCANOIL; R5 Y R6 SON INDEPENDIENTEMENTE HIDROGENO, HIDROXIL, ALQUIL, ALCOXIDO, ALCANOILOXIDO, CIANO, NITRO, ALQUILMERCAPTO, AMINO, ALQUILAMINO, DIALQUILAMINO, ALCANOILAMINO, HALO, TRIFLUOROMETIL O TOMADAS JUNTAS DIOXIDO DE METILENO; R7 ES HIDROGENO O ALQUIL; Y N ES 0, 1, 2, 3 O 4; ASIMISMO SE PRESENTAN LAS SALES FARMACOLOGICAMENTE ACEPTABLES DEL COMPUESTO.
ES94304252T 1993-06-28 1994-06-13 Nuevos tratamientos que utilizan derivados de fenetilo. Expired - Lifetime ES2174864T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8384893A 1993-06-28 1993-06-28

Publications (1)

Publication Number Publication Date
ES2174864T3 true ES2174864T3 (es) 2002-11-16

Family

ID=22181084

Family Applications (3)

Application Number Title Priority Date Filing Date
ES01115854T Expired - Lifetime ES2273764T3 (es) 1993-06-28 1994-06-13 Nuevos tratamientos que utilizan derivados de fenetilamina.
ES94304252T Expired - Lifetime ES2174864T3 (es) 1993-06-28 1994-06-13 Nuevos tratamientos que utilizan derivados de fenetilo.
ES06017469T Expired - Lifetime ES2304041T3 (es) 1993-06-28 1994-06-13 Nuevos tratamientos que utilizan derivados de fenetilamina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES01115854T Expired - Lifetime ES2273764T3 (es) 1993-06-28 1994-06-13 Nuevos tratamientos que utilizan derivados de fenetilamina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES06017469T Expired - Lifetime ES2304041T3 (es) 1993-06-28 1994-06-13 Nuevos tratamientos que utilizan derivados de fenetilamina.

Country Status (16)

Country Link
US (8) US5916923A (es)
EP (3) EP0639374B1 (es)
JP (2) JPH0789851A (es)
KR (1) KR100342762B1 (es)
AT (3) ATE392893T1 (es)
AU (2) AU6592994A (es)
CA (1) CA2126305C (es)
CY (1) CY2315B1 (es)
DE (3) DE69434872T2 (es)
DK (3) DK1153603T3 (es)
ES (3) ES2273764T3 (es)
HK (1) HK1038880B (es)
LV (1) LV12881B (es)
PT (3) PT1738753E (es)
PY (1) PY0101636A (es)
SG (1) SG47711A1 (es)

Families Citing this family (56)

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EP1096927A4 (en) * 1998-07-16 2002-09-04 Massachusetts Inst Technology COMPOSITION FOR THE TREATMENT OF STRESS
US6579899B1 (en) 1998-07-16 2003-06-17 Massachusetts Institute Of Technology Composition for treatment of stress
US6342533B1 (en) 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
HUP0200898A3 (en) 1999-04-06 2005-09-28 Sepracor Inc Derivatives of venlafaxine and methods of preparing and using the same
US7291646B2 (en) 1999-11-24 2007-11-06 Wyeth Ethers of O-desmethyl venlafaxine
EP1246817B1 (en) * 1999-12-30 2004-06-23 H. Lundbeck A/S 4-phenyl-1-piperazinyl, -piperidinyl and -tetrahydropyridyl derivatives
US6572890B2 (en) * 2000-01-13 2003-06-03 Osmotica Corp. Osmotic device containing venlafaxine and an anti-psychotic agent
FR2807753B1 (fr) * 2000-04-13 2002-06-07 Adir Nouveaux derives d'heterocycloalkylbenzocyclobutane et d'heteroarylbenzocyclobutane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP2319826A1 (en) * 2001-02-12 2011-05-11 Wyeth LLC Succinate salt of O-desmethyl-venlafaxin
KR100421508B1 (ko) * 2001-08-07 2004-03-09 김정한 항균 및 항진균 활성을 갖는 신규한 펜에틸아민 유도체와이의 염
AU2002348266A1 (en) * 2001-12-05 2003-06-23 Wyeth Novel crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof
UA77234C2 (en) * 2001-12-05 2006-11-15 Wyeth Corp Monohydrate of venlafaxine hydrochloride and methods for its preparation (variants)
US20030191347A1 (en) * 2002-03-28 2003-10-09 Rolf Keltjens Venlafaxine base
AU2003219117A1 (en) * 2002-03-28 2003-10-13 Synthon B.V. Extended release venlafaxine formulations
WO2003082805A1 (en) 2002-03-28 2003-10-09 Synthon B.V. Low water-soluble venlafaxine salts
US6717015B2 (en) 2002-03-28 2004-04-06 Synthon Bv Venlafaxine besylate
US20040002500A1 (en) * 2002-06-28 2004-01-01 Fabre Kramer Pharmaceutical, Inc. Methods for treating attention deficit disorder
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US20070077301A1 (en) * 2002-12-23 2007-04-05 Meyer Glenn A Venlafaxine osmotic device formulation
WO2004075902A1 (en) * 2003-02-28 2004-09-10 Amedis Pharmaceuticals Ltd. Use of silicon derivatives of venlafaxine for the treatment or prevention of psoriasis or panic disorder
US20050048118A1 (en) * 2003-07-25 2005-03-03 Joan Cucala Escoi Modified release venlafaxine hydrochloride tablets
US7470435B2 (en) * 2003-11-17 2008-12-30 Andrx Pharmaceuticals, Llc Extended release venlafaxine formulation
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US20050142203A1 (en) * 2003-12-30 2005-06-30 Grant Heinicke Oral dosage formulations of active pharmaceutical ingredients and methods of preparing the same
US20050226923A1 (en) * 2004-04-07 2005-10-13 Gassert Chad M Venlafaxine compositions in the form of microtablets
RU2281788C2 (ru) * 2004-04-19 2006-08-20 Николай Иванович Косенков Способ ультрапарадоксальной психотерапии в лечении психосоматических заболеваний и измененных функциональных состояний человека
RU2276999C2 (ru) * 2004-05-06 2006-05-27 Анатолий Викторович Осницкий Метод коррекции психических состояний и лечения невротических расстройств и патологических зависимостей "интегрально-синергетическая психотерапия"
RU2270036C1 (ru) * 2004-07-14 2006-02-20 Государственное учреждение "Нижегородский научно-исследовательский институт травматологии и ортопедии Министерства здравоохранения Российской Федерации" Способ коррекции психоэмоциональных и психосоматических расстройств у детей с термической травмой
US7776358B2 (en) * 2004-07-22 2010-08-17 Synthon Ip Inc. Extended release venlafaxine besylate tablets
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US20060193912A1 (en) * 2005-02-28 2006-08-31 Penwest Pharmaceuticals Co. Controlled release O-desmethylvenlafaxine formulations
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AU2006239942A1 (en) * 2005-04-22 2006-11-02 Wyeth Dihydrobenzofuran derivatives and uses thereof
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CA2625832A1 (en) * 2005-10-19 2007-04-26 Vinod Kumar Kansal Process for the preparation of highly pure 1-[2-dimethylamino-(4-methoxyphenyl) ethyl]cyclohexanol hydrochloride
PT1954669E (pt) * 2005-12-01 2015-10-23 Auspex Pharmaceuticals Inc Feniletilaminas substituídas com actividade serotoninérgica e/ou norepinefrinérgica
JP2009518407A (ja) 2005-12-05 2009-05-07 ワイス 置換１−（２−アミノ−１−フェニル−エチル）−シクロヘキサノールのエナンチオマーを選択的に合成するための方法
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US20080081067A1 (en) * 2006-10-03 2008-04-03 Gupta Manishkumar Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
RU2009112105A (ru) * 2006-10-25 2010-11-27 Вайет (Us) Выделенные гидрокси- и n-оксидные метаболиты и производные о-дезметилвенлафаксина и способы лечения
ES2693948T3 (es) * 2007-03-15 2018-12-14 Auspex Pharmaceuticals, Inc. Fenetilamina sustituida con actividad serotoninérgica y/o norepinefrinérgica
WO2009023820A1 (en) * 2007-08-16 2009-02-19 Cypress Biosciences, Inc. Improving the tolerability of a serotonin antagonist and a nsri, a snri or a rima by using them in combination
WO2009065845A1 (en) * 2007-11-20 2009-05-28 Neurosearch A/S A method for treating over-eating disorders
KR100965527B1 (ko) 2008-05-08 2010-06-23 제일약품주식회사 신규(4-(2-(디메틸아미노)-1-(1-하이드록시사이클로헥실)에틸)페녹시)포스페이트 또는 이의 약학적으로 허용가능한 염,이의 제조방법 및 이를 유효성분으로 함유하는 중추신경계질환 예방 및 치료용 조성물
CZ301820B6 (cs) * 2009-02-06 2010-06-30 Zentiva, K.S. Nové soli desvenlafaxinu a zpusob jejich prípravy
US20140116656A1 (en) * 2012-10-25 2014-05-01 Inhon International Co., Ltd Heat dissipation module and electronic device with the same
KR102132304B1 (ko) 2020-02-17 2020-07-09 박광순 접이식 유아용 비데
RU2741226C1 (ru) * 2020-09-08 2021-01-22 федеральное государственное бюджетное образовательное учреждение высшего образования "Ростовский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО РостГМУ Минздрава России) Способ профилактики агрессии лиц с интернет-зависимостью

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Also Published As

Publication number Publication date
DE69434872T2 (de) 2007-04-05
KR950000139A (ko) 1995-01-03
EP1738753A2 (en) 2007-01-03
KR100342762B1 (ko) 2002-11-18
EP0639374A3 (en) 1995-08-02
EP0639374B1 (en) 2002-02-20
EP1153603A3 (en) 2003-05-21
US5916923A (en) 1999-06-29
US6310101B1 (en) 2001-10-30
US6444708B2 (en) 2002-09-03
CA2126305A1 (en) 1994-12-29
AU5831298A (en) 1998-05-21
EP1153603B1 (en) 2006-10-18
JPH0789851A (ja) 1995-04-04
US20010012855A1 (en) 2001-08-09
US6555586B2 (en) 2003-04-29
DK0639374T3 (da) 2002-05-06
PT1738753E (pt) 2008-06-19
DK1738753T3 (da) 2008-08-11
US20080176950A1 (en) 2008-07-24
US6730706B2 (en) 2004-05-04
ATE213407T1 (de) 2002-03-15
ATE392893T1 (de) 2008-05-15
ATE342715T1 (de) 2006-11-15
LV12881B (en) 2002-11-20
CY2315B1 (en) 2003-11-14
ES2304041T3 (es) 2008-09-01
AU6592994A (en) 1995-01-05
EP1153603A2 (en) 2001-11-14
US6465524B2 (en) 2002-10-15
DE69434872D1 (de) 2006-11-30
US20030181517A1 (en) 2003-09-25
DE69429895D1 (de) 2002-03-28
ES2273764T3 (es) 2007-05-16
EP1738753B1 (en) 2008-04-23
HK1038880A1 (en) 2002-04-04
JP2006117689A (ja) 2006-05-11
EP0639374A2 (en) 1995-02-22
EP1738753A3 (en) 2007-01-31
DE69435095D1 (de) 2008-06-05
US20010053799A1 (en) 2001-12-20
CA2126305C (en) 2006-10-17
DK1153603T3 (da) 2006-12-18
DE69435095T2 (de) 2009-07-02
HK1038880B (en) 2006-12-22
PY0101636A (es) 2001-12-03
US20040110829A1 (en) 2004-06-10
DE69429895T2 (de) 2002-08-29
PT1153603E (pt) 2007-01-31
SG47711A1 (en) 1998-04-17
US20020052405A1 (en) 2002-05-02
PT639374E (pt) 2002-07-31

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