ES2175171T3 - Procedimiento para la fabricacion de un polimero cristalino de hidrocloruro de terazosina. - Google Patents

Procedimiento para la fabricacion de un polimero cristalino de hidrocloruro de terazosina.

Info

Publication number
ES2175171T3
ES2175171T3 ES96943936T ES96943936T ES2175171T3 ES 2175171 T3 ES2175171 T3 ES 2175171T3 ES 96943936 T ES96943936 T ES 96943936T ES 96943936 T ES96943936 T ES 96943936T ES 2175171 T3 ES2175171 T3 ES 2175171T3
Authority
ES
Spain
Prior art keywords
hydrocloride
terazosine
polymer
procedure
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96943936T
Other languages
English (en)
Inventor
Christophe Bauer
Jean-Marie Grunenwald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CU Chemie Uetikon GmbH
Original Assignee
CU Chemie Uetikon GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CU Chemie Uetikon GmbH filed Critical CU Chemie Uetikon GmbH
Application granted granted Critical
Publication of ES2175171T3 publication Critical patent/ES2175171T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Silicon Polymers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN POLIMORFO CRISTALINO DE MONOCLORHIDRATO DE TERAZOSINA SE OBTIENE SUSPENDIENDO Y TRATANDO UN ADUCTO CRISTALINO DE CLORHIDRATO DE TERAZOSINA Y METANOL EN UN DISOLVENTE POLAR, EL CUAL ES UN ALCOHOL CON DOS A SEIS ATOMOS DE CARBONO O UNA CETONA CON DOS A SEIS ATOMOS DE CARBONO O UNA MEZCLA DE LOS MISMOS. EL POLIMORFO CRISTALINO ASI OBTENIDO SE CARACTERIZA POR LA BAJA HIGROSCOPICIDAD Y REDUCIDA CAPACIDAD DE RETENCION DEL DISOLVENTE RESIDUAL.
ES96943936T 1995-12-13 1996-12-12 Procedimiento para la fabricacion de un polimero cristalino de hidrocloruro de terazosina. Expired - Lifetime ES2175171T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19546573A DE19546573A1 (de) 1995-12-13 1995-12-13 Kristallines Polymorph von Terazosin-Hydrochlorid, sowie Verfahren zu seiner Herstellung

Publications (1)

Publication Number Publication Date
ES2175171T3 true ES2175171T3 (es) 2002-11-16

Family

ID=7780037

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96943936T Expired - Lifetime ES2175171T3 (es) 1995-12-13 1996-12-12 Procedimiento para la fabricacion de un polimero cristalino de hidrocloruro de terazosina.

Country Status (8)

Country Link
US (1) US5959108A (es)
EP (1) EP0866792B1 (es)
AT (1) ATE216383T1 (es)
DE (2) DE19546573A1 (es)
ES (1) ES2175171T3 (es)
PT (1) PT866792E (es)
WO (1) WO1997021705A1 (es)
ZA (1) ZA9610406B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5952003A (en) * 1996-08-01 1999-09-14 Novartis Corporation Terazosin capsules
IT1286790B1 (it) * 1996-11-29 1998-07-17 Alfa Chem Ital Processo per la produzione della forma i del terazosin monocloridrato anidro
IT1286789B1 (it) * 1996-11-29 1998-07-17 Alfa Chem Ital Processo per la produzione della forma i del terazosin monocloridato anidro
IL156394A0 (en) * 2000-12-18 2004-01-04 Cubist Pharm Inc Methods for preparing purified lipopeptides
US20060014674A1 (en) * 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
DE10223913A1 (de) * 2002-05-29 2003-12-11 Bayer Cropscience Ag Verfahren zur Herstellung spezifischer Kristallmodifikationen polymorpher Substanzen
US20060264442A1 (en) * 2005-05-18 2006-11-23 Allergan, Inc. Methods for the treatment of ocular and neurodegenerative conditions in a mammal
EP3394326B1 (en) 2015-12-21 2022-09-14 The University Of British Columbia Highly parallel assays for simultaneous identification of antibody sequences and binding partners
CN119528888A (zh) * 2024-12-05 2025-02-28 迪嘉药业集团股份有限公司 一种小粒度盐酸特拉唑嗪的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
US5212176A (en) * 1990-06-29 1993-05-18 Abbott Laboratories R(+)-terazosin
JP2652272B2 (ja) * 1990-12-31 1997-09-10 住化ファインケム株式会社 １−（４−アミノ−６，７−ジメトキシ−２−キナゾリニル）−４−（２−テトラヒドロフロイル）ピペラジン塩酸塩の新規な結晶体および該結晶体の製造方法
US5294615A (en) * 1993-04-29 1994-03-15 Abbott Laboratories Terazosin polymorph and pharmaceutical composition
US5412095A (en) * 1993-04-29 1995-05-02 Abbott Laboratories Terazosin monohydrochloride and processes and intermediate for its production
US5504207A (en) * 1994-10-18 1996-04-02 Abbott Laboratories Process and intermediate for the preparation of terazosin hydrochloride dihydrate
US5587377A (en) * 1995-10-24 1996-12-24 Invamed, Inc. Terazosin crystalline polymorph and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
ZA9610406B (en) 1998-06-11
ATE216383T1 (de) 2002-05-15
EP0866792A1 (de) 1998-09-30
US5959108A (en) 1999-09-28
WO1997021705A1 (de) 1997-06-19
EP0866792B1 (de) 2002-04-17
DE59609108D1 (de) 2002-05-23
PT866792E (pt) 2002-09-30
DE19546573A1 (de) 1997-06-19

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