ES2176342T3 - Secuencias del genotipo 7 del virus de la hepatitis c y su utilizacioncomo agentes profilacticos, terapeuticos y de diagnostico. - Google Patents
Secuencias del genotipo 7 del virus de la hepatitis c y su utilizacioncomo agentes profilacticos, terapeuticos y de diagnostico.Info
- Publication number
- ES2176342T3 ES2176342T3 ES95936537T ES95936537T ES2176342T3 ES 2176342 T3 ES2176342 T3 ES 2176342T3 ES 95936537 T ES95936537 T ES 95936537T ES 95936537 T ES95936537 T ES 95936537T ES 2176342 T3 ES2176342 T3 ES 2176342T3
- Authority
- ES
- Spain
- Prior art keywords
- type
- sequences
- hcv
- new
- subtipos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A NUEVAS SECUENCIAS DE NUCLEOTIDOS GENOMICOS Y A LAS SECUENCIAS DE AMINOACIDOS CORRESPONDIENTES A LA REGION DE CODIFICACION DE ESTOS GENOMAS. LA INVENCION SE REFIERE A NUEVAS SECUENCIAS DE TIPOS Y SUBTIPOS DE HCV QUE SON DIFERENTES DE LAS SECUENCIAS DE TIPOS Y SUBTIPOS DE HCV CONOCIDAS. EN PARTICULAR, LA PRESENTE INVENCION SE REFIERE A NUEVAS SECUENCIAS DEL HCV TIPO 7, NUEVAS SECUENCIAS DEL HCV TIPO 9, NUEVAS SECUENCIAS DEL HCV TIPO 10 Y NUEVAS SECUENCIAS DEL HCV TIPO 11. LA PRESENTE INVENCION TAMBIEN SE REFIERE A NUEVAS SECUENCIAS DE LOS SUBTIPOS 1D, 1E, 1F Y 1G DEL HCV TIPO 1; NUEVAS SECUENCIAS DE LOS SUBTIPOS 2E, 2F, 2G, 2H, 2I, 2K Y 2L DEL HCV TIPO 2; NUEVAS SECUENCIAS DEL SUBTIPO 3G DEL HCV TIPO 3; NUEVAS SECUENCIAS DE LOS SUBTIPOS 4K, 4L Y 4M DEL HCV TIPO 4; A UN PROCESO PARA LA PREPARACION DE LAS MISMAS Y A SU USO PARA DIAGNOSTICOS, PROFILAXIS Y TERAPIAS. EN PARTICULAR, EN LA PRESENTE INVENCION SE PRESENTAN NUEVAS SECUENCIAS ESPECIFICAS PARA LOS TIPOSDE LAS REGIONES DEL NUCLEO, LAS REGIONES E1 Y LA NS5 DE NUEVOS HCV TIPO 7, 9, 10 Y 11, ASI COMO NUEVAS VARIANTES (SUBTIPOS) DE LOS HCV TIPO 1, 2, 3 Y 4. ESTAS SECUENCIAS NUEVAS DE HCV SON UTILES PARA DIAGNOSTICAR LA PRESENCIA GENOTIPOS O SEROTIPOS DEL HCV TIPO 1 Y/O TIPO 2 Y/O TIPO 3 Y/O TIPO 4 Y/O TIPO 7 Y/O TIPO 9 Y/O TIPO 10 Y/O TIPO 11 EN UNA MUESTRA BIOLOGICA. ADEMAS, LA DISPONIBILIDAD DE ESTAS NUEVAS SECUENCIAS ESPECIFICAS PARA LOS TIPOS PUEDE AUMENTAR LA SENSIBILIDAD GENERAL DE DETECCION DEL HCV Y DEBERIA DEMOSTRAR TAMBIEN SU UTILIDAD PARA FINES PROFILACTICOS Y TERAPEUTICOS.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP94870166 | 1994-10-21 | ||
| EP94870166 | 1994-10-21 | ||
| EP95870076 | 1995-06-28 | ||
| EP95870076 | 1995-06-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2176342T3 true ES2176342T3 (es) | 2002-12-01 |
| ES2176342T5 ES2176342T5 (es) | 2010-02-09 |
Family
ID=26137782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95936537T Expired - Lifetime ES2176342T5 (es) | 1994-10-21 | 1995-10-23 | Secuencias del genotipo 7 del virus de la hepatitis c y su utilizacion como agentes profilacticos, terapeuticos y de diagnosticos. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7129337B1 (es) |
| EP (2) | EP0804584B2 (es) |
| JP (2) | JPH10507643A (es) |
| AT (1) | ATE218617T1 (es) |
| AU (1) | AU702436B2 (es) |
| BR (1) | BR9509421A (es) |
| CA (1) | CA2201703A1 (es) |
| DE (1) | DE69526973T3 (es) |
| DK (1) | DK0804584T3 (es) |
| ES (1) | ES2176342T5 (es) |
| PT (1) | PT804584E (es) |
| WO (1) | WO1996013590A2 (es) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9620075D0 (en) * | 1996-09-26 | 1996-11-13 | Dynal As | Method |
| US7078500B1 (en) * | 1998-01-30 | 2006-07-18 | The General Hospital Corporation | Genetic immunization with nonstructural proteins of hepatitis C virus |
| CZ298268B6 (cs) | 1998-04-17 | 2007-08-08 | Innogenetics N. V. | Imunodiagnostický test používající redukující cinidla |
| DE19980730D2 (de) * | 1998-04-28 | 2001-05-10 | Wolfgang Bergter | Radioimmunpharmaka zur Therapie der Hepatitis C |
| EP1090033B2 (en) * | 1998-06-24 | 2007-12-19 | Innogenetics N.V. | Particles of hcv envelope proteins: use for vaccination |
| AU2001292151B2 (en) * | 2000-08-17 | 2006-05-04 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| US6680059B2 (en) * | 2000-08-29 | 2004-01-20 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| US6858590B2 (en) | 2000-08-17 | 2005-02-22 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
| US7101561B2 (en) | 2000-12-01 | 2006-09-05 | Innogenetics N.V. | Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use |
| GB0126782D0 (en) * | 2001-11-07 | 2002-01-02 | Medical Res Council | Assay |
| ES2596753T3 (es) * | 2003-08-29 | 2017-01-11 | Fujirebio Europe N.V. | Nuevo clado del virus de la hepatitis C y secuencias prototipo del mismo |
| JP5138230B2 (ja) | 2004-01-07 | 2013-02-06 | サード・ウェーブ・テクノロジーズ・インク | C型肝炎ウイルスの遺伝子型の決定方法 |
| RU2267496C2 (ru) * | 2004-01-15 | 2006-01-10 | Сергей Иванович Черныш | Противоопухолевые и антивирусные пептиды |
| WO2007031867A2 (en) * | 2005-05-25 | 2007-03-22 | Tripep Ab | A hepatitis c virus non-stru tural ns3/4a fusion gene |
| US7919242B2 (en) | 2005-06-30 | 2011-04-05 | Roche Molecular Systems, Inc. | Light emission modifiers and their uses in nucleic acid detection, amplification and analysis |
| MX2008007477A (es) | 2005-12-12 | 2008-09-03 | Ac Immune Sa | Anticuerpos monoclonales especificos 1-42 beta con propiedades terapeuticas. |
| PT2046833E (pt) | 2006-07-14 | 2013-11-27 | Genentech Inc | Anticorpo humanizado contra amilóide beta |
| NZ574188A (en) | 2006-07-14 | 2012-05-25 | Ac Immune Sa | Humanized antibody against amyloid beta |
| EP2061805B1 (en) * | 2006-08-25 | 2020-02-12 | Macfarlane Burnet Institute for Medical Research and Public Health Limited | Recombinant hcv e2 glycoprotein |
| EP2463390A1 (en) | 2006-10-20 | 2012-06-13 | Innogenetics N.V. | Methodology for analysis of sequence variations within the HCV NS5B genomic region |
| WO2008046923A2 (en) | 2006-10-20 | 2008-04-24 | Innogenetics N.V. | Methodology for analysis of sequence variations within the hcv ns3/4a genomic region |
| BRPI0719379A2 (pt) | 2006-11-24 | 2014-02-11 | Ac Immune Sa | Composto, composição farmacêutica, uso de composto, mistura, métodos para coletar dados para o diagnóstico de uma doença ou condição associada com amilóide em uma amostra ou um paciente, para determinar a extensão da carga de placa amiloidogênica em um tecido e/ou um fluido corporal, para coletar dados para determinar a predisposição a uma doença ou condição associada com amilóide em um paciente, para coletar dados para monitorar a doença residual mínima em um paciente seguindo o tratamento com um anticorpo ou uma composição de vacina e para coletar dados para predizer a responsividade de um paciente sendo tratado com um anticorpo ou uma composição de vacina, e, kit de teste |
| DK2170389T3 (en) | 2007-06-12 | 2015-01-19 | Ac Immune Sa | Humanized antibodies against amyloid beta |
| EP2527366B1 (en) | 2007-06-12 | 2017-08-16 | AC Immune S.A. | Monoclonal anti beta amyloid antibody |
| WO2009022939A1 (en) * | 2007-08-09 | 2009-02-19 | Uchrezhdenie Rossiiskoi Akademii Nauk Institut Molekulyarnoi Biologii Im. V.A. Engelgardta Ran (Imb Ran) | Method for identifying the genotype and subtype of hepatitis c virus on a biological microchip |
| WO2009022236A2 (en) | 2007-08-16 | 2009-02-19 | Tripep Ab | Immunogen platform |
| EP2650308A3 (en) | 2007-10-05 | 2014-11-12 | Genentech, Inc. | Use of anti-amyloid beta antibody in ocular diseases |
| WO2009130588A2 (en) * | 2008-04-22 | 2009-10-29 | Tripep Ab | Immunogen platform |
| EP2311823A1 (en) | 2009-10-15 | 2011-04-20 | AC Immune S.A. | 2,6-Diaminopyridine compounds for treating diseases associated with amyloid proteins or for treating ocular diseases |
| US20110256064A1 (en) | 2010-04-16 | 2011-10-20 | Ac Immune, S.A. | Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-like Proteins |
| AU2011239966B2 (en) | 2010-04-16 | 2014-05-08 | Ac Immune S.A. | Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins |
| US8962241B2 (en) * | 2010-07-20 | 2015-02-24 | California Institute Of Technology | Triggered molecular geometry based bioimaging probes |
| AU2011282536B2 (en) | 2010-07-30 | 2015-12-24 | Ac Immune S.A. | Safe and functional humanized anti beta-amyloid antibody |
| PE20140218A1 (es) | 2010-10-07 | 2014-03-01 | Ac Inmune S A | Composicion farmaceutica |
| JP6027011B2 (ja) | 2010-10-26 | 2016-11-16 | エーシー イミューン ソシエテ アノニム | 疎水性部分によって修飾されたペプチドを含むリポソームベースの構築物 |
| ES2600915T3 (es) | 2011-10-07 | 2017-02-13 | Ac Immune S.A. | Anticuerpos fosfoespecíficos que reconocen Tau |
| EP2834270B1 (en) | 2012-04-05 | 2019-10-30 | AC Immune S.A. | Humanized tau antibody |
| JP6498600B2 (ja) | 2012-06-08 | 2019-04-10 | ストロ バイオファーマ インコーポレーテッド | 部位特異的な非天然アミノ酸残基を含む抗体、その調製方法、及びその使用方法 |
| EP2863955B1 (en) | 2012-06-26 | 2016-11-23 | Sutro Biopharma, Inc. | Modified fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use |
| CN102766701B (zh) * | 2012-07-04 | 2016-05-04 | 福州泰普生物科学有限公司 | 丙型肝炎病毒基因分型的试剂盒及方法 |
| DK2890402T3 (da) | 2012-08-31 | 2019-07-15 | Sutro Biopharma Inc | Modificerede aminosyrer omfattende en azidogruppe |
| BR112015023262B8 (pt) | 2013-03-15 | 2024-02-06 | Ac Immune Sa | Anticorpo isolado, imunoconjugado, formulação farmacêutica e usos do anticorpo |
| RU2667429C2 (ru) * | 2013-05-10 | 2018-09-19 | Соединенные Штаты Америки, В Лице Секретаря, Департамента Здравоохранения И Социального Обеспечения Сша | Композиции и способы для одновременного обнаружения hcv антигена/антитела |
| WO2015006555A2 (en) | 2013-07-10 | 2015-01-15 | Sutro Biopharma, Inc. | Antibodies comprising multiple site-specific non-natural amino acid residues, methods of their preparation and methods of their use |
| PT3041864T (pt) | 2013-09-05 | 2021-10-26 | Ab2 Bio Sa | Proteína de ligação a il-18 (il-18bp) em doenças inflamatórias |
| US9840493B2 (en) | 2013-10-11 | 2017-12-12 | Sutro Biopharma, Inc. | Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use |
| UA128752C2 (uk) | 2015-03-05 | 2024-10-16 | Аб2 Біо Са | Фармацевтична композиція для лікування асоційованого з il-18 захворювання або порушення |
| WO2017218698A1 (en) | 2016-06-15 | 2017-12-21 | Sutro Biopharma, Inc. | Antibodies with engineered ch2 domains, compositions thereof and methods of using the same |
| GB201807367D0 (en) | 2018-05-04 | 2018-06-20 | Univ Newcastle | Biomarker |
| US20230095053A1 (en) | 2020-03-03 | 2023-03-30 | Sutro Biopharma, Inc. | Antibodies comprising site-specific glutamine tags, methods of their preparation and methods of their use |
| WO2021224432A1 (en) | 2020-05-06 | 2021-11-11 | Ab2 Bio Sa | Il-18 binding protein (il-18bp) in respiratory diseases |
| EP3943097A1 (en) | 2020-07-24 | 2022-01-26 | AB2 Bio SA | Car-t cell therapy |
| CA3244428A1 (en) | 2022-03-04 | 2023-09-07 | Ab2 Bio Sa | IL-18 BINDING PROTEIN (IL-18BP) IN THE TREATMENT OF VEXAS SYNDROME |
| WO2024006563A1 (en) | 2022-07-01 | 2024-01-04 | Sutro Biopharma, Inc. | Il-12 mutants with reduced toxicity, compositions thereof and methods of using the same |
| WO2024044780A1 (en) | 2022-08-26 | 2024-02-29 | Sutro Biopharma, Inc. | Interleukin-18 variants and uses thereof |
| WO2024098023A2 (en) | 2022-11-04 | 2024-05-10 | Sutro Biopharma, Inc. | Interferon alpha polypeptides and conjugates |
| WO2026043823A2 (en) | 2024-08-19 | 2026-02-26 | Sutro Biopharma, Inc. | Antibodies comprising site-specific non-natural amino acid residues, methods of preparation and uses thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU225068B1 (en) † | 1989-03-17 | 2006-05-29 | Chiron Corp | Process for producing diagnostics and vaccine of nanbh |
| JP3156200B2 (ja) | 1989-09-15 | 2001-04-16 | 国立予防衛生研究所長 | 新規のhcv分離株 |
| US5372928A (en) | 1989-09-15 | 1994-12-13 | Chiron Corporation | Hepatitis C virus isolates |
| CA2032381C (en) | 1989-12-18 | 2006-02-21 | Peter E. Highfield | Viral agent |
| NZ238681A (en) | 1990-06-25 | 1992-03-26 | Univ Osaka Res Found | Non-a, non-b hepatitis virus particles and their production |
| HU227548B1 (en) | 1991-05-08 | 2011-08-29 | Novartis Vaccines & Diagnostic | Process for production of non-naturally occuring non-hcv-1 nucleic acids, forming a hybridization product, and detecting hcv genotypes |
| KR0185426B1 (ko) * | 1991-06-24 | 1999-04-01 | 로버트 피. 블랙버언 | 씨형 간염 바이러스 폴리펩티드 |
| EP0532167A3 (en) | 1991-08-09 | 1993-03-31 | Immuno Japan Inc. | Non-a, non-b hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems |
| DE69232859T2 (de) * | 1991-09-13 | 2003-04-10 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | Zusammensetzung aus mehreren immunreaktiven hepatitis-c-virus-polypeptiden |
| ES2065863T3 (es) | 1991-11-21 | 2003-09-01 | Common Services Agency | Analisis para la deteccion de virus de la hepatitis c. |
| ATE551423T1 (de) * | 1993-04-27 | 2012-04-15 | Innogenetics Nv | Sequenzen von hepatitis c virus-genotypen sowie ihre verwendungen als therapeutika und diagnostika |
| JPH06319563A (ja) * | 1993-05-13 | 1994-11-22 | Imuno Japan:Kk | C型肝炎ウイルス遺伝子、オリゴヌクレオチド、並びにc型 肝炎ウイルス遺伝子型判定方法 |
| US5514539A (en) | 1993-06-29 | 1996-05-07 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
-
1995
- 1995-10-23 DE DE69526973T patent/DE69526973T3/de not_active Expired - Lifetime
- 1995-10-23 EP EP95936537A patent/EP0804584B2/en not_active Expired - Lifetime
- 1995-10-23 US US08/836,075 patent/US7129337B1/en not_active Expired - Fee Related
- 1995-10-23 CA CA002201703A patent/CA2201703A1/en not_active Abandoned
- 1995-10-23 PT PT95936537T patent/PT804584E/pt unknown
- 1995-10-23 WO PCT/EP1995/004155 patent/WO1996013590A2/en not_active Ceased
- 1995-10-23 ES ES95936537T patent/ES2176342T5/es not_active Expired - Lifetime
- 1995-10-23 BR BR9509421A patent/BR9509421A/pt not_active Application Discontinuation
- 1995-10-23 AU AU38440/95A patent/AU702436B2/en not_active Ceased
- 1995-10-23 DK DK95936537T patent/DK0804584T3/da active
- 1995-10-23 JP JP8514299A patent/JPH10507643A/ja active Pending
- 1995-10-23 EP EP00118731A patent/EP1076092A3/en not_active Withdrawn
- 1995-10-23 AT AT95936537T patent/ATE218617T1/de not_active IP Right Cessation
-
2001
- 2001-05-09 US US09/851,138 patent/US6974864B2/en not_active Expired - Fee Related
-
2004
- 2004-10-20 JP JP2004305574A patent/JP2005118044A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2201703A1 (en) | 1996-05-09 |
| WO1996013590A3 (en) | 1996-08-15 |
| WO1996013590A2 (en) | 1996-05-09 |
| AU702436B2 (en) | 1999-02-18 |
| US6974864B2 (en) | 2005-12-13 |
| EP0804584B1 (en) | 2002-06-05 |
| US20020183508A1 (en) | 2002-12-05 |
| EP1076092A2 (en) | 2001-02-14 |
| JP2005118044A (ja) | 2005-05-12 |
| JPH10507643A (ja) | 1998-07-28 |
| DE69526973T3 (de) | 2010-01-07 |
| BR9509421A (pt) | 1997-09-30 |
| ES2176342T5 (es) | 2010-02-09 |
| AU3844095A (en) | 1996-05-23 |
| DE69526973D1 (de) | 2002-07-11 |
| EP0804584B2 (en) | 2008-07-09 |
| DK0804584T3 (da) | 2002-09-23 |
| ATE218617T1 (de) | 2002-06-15 |
| DE69526973T2 (de) | 2003-01-02 |
| EP0804584A1 (en) | 1997-11-05 |
| US7129337B1 (en) | 2006-10-31 |
| EP1076092A3 (en) | 2001-03-28 |
| PT804584E (pt) | 2002-11-29 |
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