ES2176399T3 - Induccion de la tolerancia a la leche de vaca. - Google Patents
Induccion de la tolerancia a la leche de vaca.Info
- Publication number
- ES2176399T3 ES2176399T3 ES96202475T ES96202475T ES2176399T3 ES 2176399 T3 ES2176399 T3 ES 2176399T3 ES 96202475 T ES96202475 T ES 96202475T ES 96202475 T ES96202475 T ES 96202475T ES 2176399 T3 ES2176399 T3 ES 2176399T3
- Authority
- ES
- Spain
- Prior art keywords
- tolerance
- induction
- whey
- cow milk
- milk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 235000020247 cow milk Nutrition 0.000 title 1
- 230000006698 induction Effects 0.000 title 1
- 239000005862 Whey Substances 0.000 abstract 3
- 102000007544 Whey Proteins Human genes 0.000 abstract 3
- 108010046377 Whey Proteins Proteins 0.000 abstract 3
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 230000002009 allergenic effect Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 239000008267 milk Substances 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000020192 tolerance induction in gut-associated lymphoid tissue Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
- A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Feed For Specific Animals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Dairy Products (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Water Treatment By Electricity Or Magnetism (AREA)
- Soft Magnetic Materials (AREA)
Abstract
SE UTILIZA UN SUERO CON UN GRADO DE HIDROLISIS ENZIMATICA DEL 15-20 % Y UN NIVEL DE DETECCION INMUNOLOGICA DE LAS PROTEINAS ALERGENICAS POR LO MENOS 100 VECES INFERIOR AL DE UN SUERO NO HIDROLIZADO PARA FABRICAR UNA COMPOSICION DESTINADA A INDUCIR LA TOLERANCIA ORAL EN MAMIFEROS POTENCIALMENTE ALERGICOS A LA LECHE DE VACA, EN ESPECIAL EN AQUELLOS QUE TODAVIA NO HUBIERAN ESTADO EN CONTACTO CON LOS ALERGENOS DE LA LECHE DE VACA. EL SUERO HIDROLIZADO ES CAPAZ ASIMISMO DE DETERMINAR UN NIVEL DE LIBERACION DE SEROTONINA SUP,3}H POR LOS MASTOCITOS, SENSIBILIZADOS PREVIAMENTE PASIVAMENTE CON UN ANTISUERO ANTIPROTEINAS DE LECHE DE VACA, POR LO MENOS 200 VECES INFERIOR AL OBTENIDO POR LOS MISMOS MASTOCITOS CON UN SUERO NO HIDROLIZADO. POR ULTIMO, SE INDUCE UNA TOLERANCIA TAL QUE EL NIVEL DE IGE ANTIPROTEINAS ALERGIZANTES DE VACA, PRODUCIDO COMO REACCION A UNA ADMINISTRACION DE PROTEINAS ALERGIZANTES DE VACA, SE REDUCE POR LO MENOS 100 VECES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96202475A EP0827697B1 (fr) | 1996-09-06 | 1996-09-06 | Induction de la tolérance au lait de vache |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2176399T3 true ES2176399T3 (es) | 2002-12-01 |
Family
ID=8224355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96202475T Expired - Lifetime ES2176399T3 (es) | 1996-09-06 | 1996-09-06 | Induccion de la tolerancia a la leche de vaca. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0827697B1 (es) |
| AT (1) | ATE218812T1 (es) |
| DE (1) | DE69621800T2 (es) |
| ES (1) | ES2176399T3 (es) |
| PT (1) | PT827697E (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY129566A (en) * | 1999-01-19 | 2007-04-30 | Nestle Sa | A hypoallergenic composition containing tolerogenic peptides inducing oral tolerance |
| EP1034704A1 (en) * | 1999-03-12 | 2000-09-13 | Societe Des Produits Nestle S.A. | Nutritional composition intended for specific gastro-intestinal maturation in premature mammals |
| ATE330489T1 (de) * | 2001-03-01 | 2006-07-15 | Nestle Sa | Hypoallergene nahrungsmittel zur induzierung oraler toleranz gegenüber sojaproteinen |
| RU2445992C2 (ru) * | 2006-06-15 | 2012-03-27 | Нестек С.А. | Индукция толерантности к белкам яиц |
| EP2044851A1 (en) * | 2007-09-26 | 2009-04-08 | Nestec S.A. | Prevention of allergy at weaning |
| EP3097791B1 (en) | 2010-06-04 | 2018-05-16 | N.V. Nutricia | Non-digestible oligosaccharides for oral induction of tolerance against dietary proteins |
| WO2011150949A1 (en) | 2010-06-04 | 2011-12-08 | N.V. Nutricia | Non-digestible oligosaccharides for oral induction of tolerance against dietary proteins |
| EP2436389A1 (en) | 2010-10-01 | 2012-04-04 | Nestec S.A. | Milk-based protein hydrolysates and infant formulae and nutritional compositions made thereof |
| EP2465508A1 (en) | 2010-11-23 | 2012-06-20 | Nestec S.A. | Composition comprising hydrolysed proteins and oligosaccharides for treating skin diseases |
| WO2013083140A1 (en) | 2011-12-07 | 2013-06-13 | N.V. Nutricia | Beta-lactoglobulin peptides for treating cow's milk protein allergy |
| WO2019212329A1 (en) | 2018-04-30 | 2019-11-07 | N.V. Nutricia | Formula with specific beta-lactoglobulin peptides |
| WO2019212330A1 (en) | 2018-04-30 | 2019-11-07 | N.V. Nutricia | Formula with a specific beta-lactoglobulin peptide |
| WO2021091369A1 (en) | 2019-11-07 | 2021-05-14 | N.V. Nutricia | Extensive whey protein hydrolysate with tolerogenic peptides |
| CN113278058B (zh) * | 2021-05-24 | 2022-07-19 | 北京工商大学 | 一种牛乳β-乳球蛋白T细胞免疫耐受水解物及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2459620B1 (fr) * | 1979-06-26 | 1983-08-05 | Agronomique Inst Nat Rech | Hydrolisat enzymatique total de proteines de lactoserum, obtention et application |
| EP0321603A1 (fr) * | 1987-12-23 | 1989-06-28 | Societe Des Produits Nestle S.A. | Procédé de préparation d'un hydrolysat de protéines de lactosérum et d'un aliment hypoallergéniques |
| EP0322589B1 (fr) * | 1987-12-23 | 1993-01-20 | Societe Des Produits Nestle S.A. | Procédé de préparation d'un hydrolysat de protéines de lactosérum et d'un aliment hypoallergéniques |
| GB9312369D0 (en) * | 1993-06-16 | 1993-07-28 | Sandoz Nutrition Ltd | Organic compounds |
| US5405637A (en) * | 1993-06-30 | 1995-04-11 | Bristol-Myers Squibb Company | Milk protein partial hydrolysate and infant formula containing same |
-
1996
- 1996-09-06 ES ES96202475T patent/ES2176399T3/es not_active Expired - Lifetime
- 1996-09-06 DE DE69621800T patent/DE69621800T2/de not_active Expired - Fee Related
- 1996-09-06 AT AT96202475T patent/ATE218812T1/de not_active IP Right Cessation
- 1996-09-06 EP EP96202475A patent/EP0827697B1/fr not_active Revoked
- 1996-09-06 PT PT96202475T patent/PT827697E/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0827697B1 (fr) | 2002-06-12 |
| DE69621800T2 (de) | 2002-10-02 |
| PT827697E (pt) | 2002-11-29 |
| DE69621800D1 (de) | 2002-07-18 |
| ATE218812T1 (de) | 2002-06-15 |
| EP0827697A1 (fr) | 1998-03-11 |
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