ES2178876T3 - Pastillas de desintegracion rapida. - Google Patents

Pastillas de desintegracion rapida.

Info

Publication number
ES2178876T3
ES2178876T3 ES99907592T ES99907592T ES2178876T3 ES 2178876 T3 ES2178876 T3 ES 2178876T3 ES 99907592 T ES99907592 T ES 99907592T ES 99907592 T ES99907592 T ES 99907592T ES 2178876 T3 ES2178876 T3 ES 2178876T3
Authority
ES
Spain
Prior art keywords
weight
amount
pads
water
fast disintegration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99907592T
Other languages
English (en)
Other versions
ES2178876T5 (es
Inventor
Luca Dobetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adare Pharmaceuticals SRL
Original Assignee
Eurand International SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8231542&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2178876(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eurand International SpA filed Critical Eurand International SpA
Publication of ES2178876T3 publication Critical patent/ES2178876T3/es
Application granted granted Critical
Publication of ES2178876T5 publication Critical patent/ES2178876T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)

Abstract

Pastilla de desintegración rápida compuesta por un medicamento en forma de multipartículas, caracterizada en que contiene: (I) componentes sustancialmente insolubles en agua en una cantidad de entre un 50 y un 99,5% por peso, preferentemente 65-98%, o más preferentemente entre un 70 y un 95%. (II)uno o más excipientes inorgánicos insolubles en agua, en una cantidad de entre un 2 y un 40%, preferentemente 4-25%, o más preferentemente entre un 6 y un 18% por peso; (III) uno o más desintegrantes, en una cantidad de entre un 0,5 y un 30%, preferentemente entre un 1 y un 20% o más preferentemente de 2 a 15% por peso; (IV)opcionalmente, uno o más excipientes sustancialmente solubles en agua, en una cantidad de entre un 0 y un 25%, preferentemente 0-20%, o más preferentemente 4-16% por peso.
ES99907592T 1998-03-06 1999-03-04 Pastilla de desintegración rápida Expired - Lifetime ES2178876T5 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98104035 1998-03-06
EP98104035 1998-03-06
PCT/EP1999/001395 WO1999044580A1 (en) 1998-03-06 1999-03-04 Fast disintegrating tablets

Publications (2)

Publication Number Publication Date
ES2178876T3 true ES2178876T3 (es) 2003-01-01
ES2178876T5 ES2178876T5 (es) 2012-10-01

Family

ID=8231542

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99907592T Expired - Lifetime ES2178876T5 (es) 1998-03-06 1999-03-04 Pastilla de desintegración rápida

Country Status (15)

Country Link
US (1) US6596311B1 (es)
EP (1) EP1058538B9 (es)
JP (1) JP2002505269A (es)
KR (1) KR20010041609A (es)
AR (1) AR018143A1 (es)
AT (1) ATE219658T1 (es)
AU (1) AU741992B2 (es)
BR (1) BR9908438A (es)
CA (1) CA2322315C (es)
DE (1) DE69901938T3 (es)
DK (1) DK1058538T3 (es)
ES (1) ES2178876T5 (es)
NZ (1) NZ507271A (es)
PT (1) PT1058538E (es)
WO (1) WO1999044580A1 (es)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071128B2 (en) * 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
US7815937B2 (en) * 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
CA2348452A1 (en) * 1998-10-27 2000-05-04 Biovail Technologies Ltd. Microparticles containing peg and/or peg glyceryl esters
CA2311734C (en) 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
US7799342B2 (en) 2000-12-06 2010-09-21 Wyeth Llc Fast dissolving tablet
US6733781B2 (en) 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
US6814978B2 (en) * 2000-12-29 2004-11-09 Mcneil-Ppc, Inc. Process for preparing a soft tablet
US20020122823A1 (en) * 2000-12-29 2002-09-05 Bunick Frank J. Soft tablet containing dextrose monohydrate
GB0113843D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
FR2834896B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible d'ivabradine
FR2834890B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible d'agomelatine
FR2834893B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible de perindopril
GB0204771D0 (en) * 2002-02-28 2002-04-17 Phoqus Ltd Fast disintegrating tablets
US20030190343A1 (en) * 2002-03-05 2003-10-09 Pfizer Inc. Palatable pharmaceutical compositions for companion animals
US6753009B2 (en) * 2002-03-13 2004-06-22 Mcneil-Ppc, Inc. Soft tablet containing high molecular weight polyethylene oxide
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
FR2838647B1 (fr) * 2002-04-23 2006-02-17 Particules enrobees a liberation prolongee, leur procede de preparation et comprimes les contenant
FR2845914B1 (fr) * 2002-10-18 2005-11-04 Schwarz Pharma Lab Compose antiemetique a desagregation rapide
WO2004047810A1 (en) * 2002-11-25 2004-06-10 Purdue Research Foundation Mannose-based fast dissolving tablets
US8367111B2 (en) * 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
WO2004064810A1 (ja) 2003-01-21 2004-08-05 Nippon Shinyaku Co., Ltd. 口腔内速崩性錠剤
JP4739217B2 (ja) * 2003-05-07 2011-08-03 サムヤン コーポレイション 速く溶ける錠剤を製造するための高可塑性顆粒
KR101125268B1 (ko) 2003-06-06 2012-04-23 에띠팜 구강 분산성 다중층 정제
US20070071810A1 (en) * 2003-08-26 2007-03-29 Kenichi Kudo Additive for tablets
US7282217B1 (en) * 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
AR045637A1 (es) 2003-09-12 2005-11-02 Amgen Inc Formulacion de disolucion rapida de un compuesto activo frente a los receptores de calcio
DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
US20050181050A1 (en) * 2004-01-28 2005-08-18 Collegium Pharmaceutical, Inc. Dosage forms using drug-loaded ion exchange resins
GB0408078D0 (en) * 2004-04-08 2004-05-12 Novartis Ag Organic compounds
US20050244343A1 (en) * 2004-04-30 2005-11-03 Withiam Michael C Oral care products comprising silica
US20050244492A1 (en) * 2004-04-30 2005-11-03 Mehra Dev K Rapidly disintegrating tablets comprising titanium dioxide
US20070196477A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly dissolving tablets comprising low surface area calcium phosphates
US20070196475A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly disintegrating low friability tablets comprising silica materials
US20050244493A1 (en) * 2004-04-30 2005-11-03 Withiam Michael C Rapidly disintegrating tablets comprising calcium carbonate
US20050244347A1 (en) * 2004-04-30 2005-11-03 Mehra Dev K Oral care products comprising calcium phosphates
US20070196474A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly disintegrating low friability tablets comprising calcium carbonate
US20070196476A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly dissolving tablets comprising low surface area titanium dioxide
JP2008502727A (ja) * 2004-06-10 2008-01-31 グラット エアー テクニクス インコーポレーテッド 徐放性基材医薬品製剤
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
WO2006047493A2 (en) 2004-10-21 2006-05-04 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
ITMI20042356A1 (it) 2004-12-10 2005-03-10 Acraf Composizione farmaceutica orodisperdibile e procedimento per prepararla
US20070036843A1 (en) * 2005-01-28 2007-02-15 Collegium Pharmaceutical, Inc. Non-ionic non-aqueous vehicles for topical and oral administration of carrier-complexed active agents
WO2006085497A1 (ja) * 2005-02-09 2006-08-17 Kissei Pharmaceutical Co., Ltd. 口腔内崩壊錠
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
GB0516604D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Rapidly dispersing/disintegrating compositions
CN102716490A (zh) * 2005-09-01 2012-10-10 卫材R&D管理有限公司 药物组合物的崩解性的改善方法
ES2393117T3 (es) 2005-09-12 2012-12-18 Actelion Pharmaceuticals Ltd. Composición farmacéutica estable que comprende una pirimidina-sulfamida
FR2891147B1 (fr) * 2005-09-28 2007-12-07 Ethypharm Sa Comprimes orodispersibles de principes actifs amers
US20070092553A1 (en) * 2005-10-21 2007-04-26 Pfab Lp Compositions and methods of making rapidly dissolving lonically masked formulations
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US20070116759A1 (en) * 2005-11-22 2007-05-24 Gershon Kolatkar Pharmaceutical compositions of telmisartan
US20090030057A1 (en) * 2005-11-22 2009-01-29 Shlomit Wizel Pharmaceutical composition of telmisartan
US20070141147A1 (en) * 2005-12-21 2007-06-21 Auriga Laboratories, Inc. Sequential release pharmaceutical formulations
US20070196491A1 (en) * 2006-01-27 2007-08-23 Eurand, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
JP5433236B2 (ja) * 2006-01-27 2014-03-05 アプタリス ファーマテック，インコーポレイテッド 弱塩基性選択性セロトニン５−ｈｔ３遮断剤および有機酸を含む薬物送達系
MY157620A (en) 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
EP1986591A1 (en) * 2006-02-10 2008-11-05 LG Household & Health Care Ltd. In-situ melting and gelling tablet composition for oral care
JP2009536164A (ja) * 2006-05-10 2009-10-08 エボニック デグサ ゲーエムベーハー ロール圧密成形した熱分解法二酸化ケイ素の医薬組成物での使用
EP2023899A1 (en) * 2006-05-10 2009-02-18 Evonik Degussa GmbH Use of roll compacted pyrogenically produced silicon dioxide in pharmaceutical compositions
EP2043613A1 (en) * 2006-07-14 2009-04-08 Fmc Corporation Solid form
MX2009001294A (es) 2006-08-04 2009-05-21 Ethypharm Sa Granulo y tableta que se desintegra por vía oral que comprende oxicodona.
ATE462416T1 (de) 2006-08-04 2010-04-15 Ethypharm Sa Mehrschichtige im mund zerfallende tablette
EP2050448A4 (en) * 2006-08-08 2012-01-04 Kissei Pharmaceutical Mouth-dropping tray with masked bitter taste and method of preparation
WO2008018086A1 (en) * 2006-08-10 2008-02-14 Bajaj Healthcare Limited Mouth dissolving pharmaceutical or nutraceutical composition
EP1897543A1 (en) 2006-08-30 2008-03-12 Euro-Celtique S.A. Buprenorphine- wafer for drug substitution therapy
US20080064694A1 (en) * 2006-09-11 2008-03-13 Auriga Laboratories, Inc. Multi-Phase Release Methscopolamine Compositions
WO2008033155A1 (en) * 2006-09-15 2008-03-20 Auriga Laboratories, Inc. Kits for prevention and treatment of rhinitis
US20080085312A1 (en) * 2006-10-04 2008-04-10 Auriga Laboratories, Inc. Multi-Phase Release Potassium Guaiacolsulfonate Compositions
EP2069062A2 (en) * 2006-10-06 2009-06-17 The President and Fellows of Harvard College Chemically-directed electrostatic self-assembly of materials
US20080085310A1 (en) * 2006-10-06 2008-04-10 Maria Oksana Bachynsky Capecitabine rapidly disintegrating tablets
MX2009006699A (es) * 2006-12-21 2009-06-30 Mallinckrodt Inc Composicion y metodo para preparar tabletas oralmente disgregantes que contienen una alta dosis de ingredientes farmaceuticamente activos.
WO2008079342A2 (en) * 2006-12-21 2008-07-03 Mallinckrodt Inc. Composition of and method for preparing orally disintegrating tablets
EP2120945A1 (en) * 2007-02-28 2009-11-25 Collegium Pharmaceutical, Inc. Antihistamine combination
US20080260823A1 (en) * 2007-04-20 2008-10-23 Sciele Pharma, Inc. Orally disintegrating tablet comprising glycopyrrolate for treating sialorrhea
WO2008135828A2 (en) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
US8703204B2 (en) 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
US20080311162A1 (en) * 2007-05-16 2008-12-18 Olivia Darmuzey Solid form
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
EP2162120B1 (en) 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
GB0714670D0 (en) 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
EP2572705B1 (en) 2007-10-01 2017-09-13 Laboratorios Lesvi, S.L. Orodispersible tablets
GB0720220D0 (en) * 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
AU2008318851B2 (en) * 2007-10-31 2014-04-17 Mcneil-Ppc, Inc. Orally disintegrated dosage form
CN101868228B (zh) 2007-11-21 2016-12-07 大日本住友制药株式会社 口腔内崩解片
EP2240162A4 (en) 2007-12-06 2013-10-09 Bend Res Inc NANOTE PARTICLES WITH A NON-IONIZABLE POLYMER AND AN AMIN-FUNCTIONALIZED METHACRYLATE COPOLYMER
WO2009073215A1 (en) 2007-12-06 2009-06-11 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
US8133506B2 (en) * 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
EP2433652B1 (en) * 2009-05-20 2016-11-09 Sumitomo Dainippon Pharma Co., Ltd. Dry-coated orally-disintegrating tablet
JP5575119B2 (ja) * 2009-05-20 2014-08-20 大日本住友製薬株式会社 口腔内崩壊錠
EP2440210A4 (en) 2009-06-12 2014-01-29 Meritage Pharma Inc METHOD FOR THE TREATMENT OF STOMACH DARM DISEASES
US20110003005A1 (en) * 2009-07-06 2011-01-06 Gopi Venkatesh Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
US8313768B2 (en) 2009-09-24 2012-11-20 Mcneil-Ppc, Inc. Manufacture of tablet having immediate release region and sustained release region
US8784781B2 (en) 2009-09-24 2014-07-22 Mcneil-Ppc, Inc. Manufacture of chewing gum product with radiofrequency
US8858210B2 (en) 2009-09-24 2014-10-14 Mcneil-Ppc, Inc. Manufacture of variable density dosage forms utilizing radiofrequency energy
KR20150043548A (ko) 2009-10-01 2015-04-22 앱탈리스 파마테크, 인코포레이티드 경구 투여용 코르티코스테로이드 조성물
SG10201407965XA (en) 2009-12-02 2015-02-27 Aptalis Pharma Ltd Fexofenadine microcapsules and compositions containing them
WO2011087705A2 (en) * 2009-12-22 2011-07-21 Fmc Corporation Fine particle croscarmellose and uses thereof
AR079862A1 (es) * 2010-01-08 2012-02-22 Eurand Inc Composicion de topiramato con sabor enmascarado, un comprimido desintegrable oralmente que comprende la misma y metodo de preparacion
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
EP2377522B1 (en) * 2010-04-15 2013-01-16 Sanovel Ilaç Sanayi Ve Ticaret Anonim Sirketi Orally disintegrating tablet formulations of mirtazapine and process for preparing the same
WO2012106058A2 (en) 2011-01-31 2012-08-09 New Market Pharmaceuticals Animal treatments
AU2012246490B2 (en) 2011-04-18 2016-08-04 Eisai R&D Management Co., Ltd. Therapeutic agent for tumor
US9433620B2 (en) 2011-05-13 2016-09-06 Cadila Healthcare Limited Pharmaceutical compositions of lurasidone
WO2012161240A1 (ja) * 2011-05-25 2012-11-29 大鵬薬品工業株式会社 テガフール、ギメラシル、オテラシルカリウム含有有核錠
JP6038128B2 (ja) 2011-06-03 2016-12-07 エーザイ・アール・アンド・ディー・マネジメント株式会社 レンバチニブ化合物に対する甲状腺癌対象及び腎臓癌対象の反応性を予測及び評価するためのバイオマーカー
JP6245677B2 (ja) * 2012-01-20 2017-12-13 ニプロ株式会社 口腔内崩壊錠
US9744134B2 (en) 2012-02-03 2017-08-29 Asahi Kasei Chemicals Corporation Orally disintegrating tablet containing bitterness-masking granules
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
EP3505159B1 (en) 2012-05-02 2020-11-04 NewMarket Pharmaceuticals LLC Pharmaceutical compositions for direct systemic introduction
US10662258B2 (en) * 2012-05-31 2020-05-26 Asahi Kasei Chemicals Corporation Cellulose powder
JPWO2014098176A1 (ja) 2012-12-21 2017-01-12 エーザイ・アール・アンド・ディー・マネジメント株式会社 キノリン誘導体のアモルファス及びその製造方法
ITMI20130210A1 (it) * 2013-02-14 2014-08-15 Menarini Lab Composizioni farmaceutiche contenenti dexketoprofene e tramadolo
GB201303781D0 (en) * 2013-03-04 2013-04-17 Gauthier Pierre Pascal Oral timer device and method of using same
CA2912219C (en) 2013-05-14 2021-11-16 Eisai R&D Management Co., Ltd. Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
WO2015034678A2 (en) 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
RU2712267C2 (ru) 2014-01-10 2020-01-28 Джонсон энд Джонсон Консьюмер Инк. Способ изготовления таблеток с использованием радиочастотного излучения и частиц с поглощающим покрытием
EP3187491A4 (en) 2014-08-28 2018-08-01 Eisai R&D Management Co., Ltd. High-purity quinoline derivative and method for manufacturing same
US20180028662A1 (en) 2015-02-25 2018-02-01 Eisai R&D Management Co., Ltd. Method for Suppressing Bitterness of Quinoline Derivative
KR20240064733A (ko) 2015-03-04 2024-05-13 머크 샤프 앤드 돔 코포레이션 암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
CA2988707C (en) 2015-06-16 2023-10-10 Eisai R&D Management Co., Ltd. Combination of cbp/catenin inhibitor and immune checkpoint inhibitor for treating cancer
CN108135894B (zh) 2015-08-20 2021-02-19 卫材R&D管理有限公司 肿瘤治疗剂
EP3389600B1 (en) * 2015-12-18 2022-02-02 Colgate-Palmolive Company Fast dissolving peroxymonosulfate composition
MX376624B (es) 2015-12-23 2025-03-07 Colgate Palmolive Co Composicion de peroximonosulfato solido de almacenamiento estable.
EP3484588B1 (en) 2016-08-11 2023-07-26 Colgate-Palmolive Company Peroxymonosulfate toothpowder composition for tenacious stains
TWI777515B (zh) 2016-08-18 2022-09-11 美商愛戴爾製藥股份有限公司 治療嗜伊紅性食道炎之方法
CN110072528B (zh) 2017-02-08 2022-04-26 卫材R&D管理有限公司 治疗肿瘤的药物组合物
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
WO2018212202A1 (en) 2017-05-16 2018-11-22 Eisai R&D Management Co., Ltd. Treatment of hepatocellular carcinoma
WO2020020999A1 (en) * 2018-07-27 2020-01-30 Sandoz Ag Process for preparing rapidly or very rapidly dissolving tablets comprising freely soluble api
US12691128B2 (en) 2019-10-01 2026-07-28 Ellodi Pharmaceuticals, L.P. Methods of treating eosinophilic esophagitis and reducing candidiasis
CN116829122B (zh) 2021-01-25 2026-03-17 高露洁-棕榄公司 包含pvp和hec作为粘合剂体系的固体口腔护理组合物
EP4199881A1 (en) 2021-02-19 2023-06-28 Colgate-Palmolive Company Peroxymonosulfate whitening strips
WO2022226369A1 (en) 2021-04-23 2022-10-27 Colgate-Palmolive Company Solid oral care compositions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH20837A (en) * 1983-04-29 1987-05-08 Pennwalt Corp Rapid dissolving uniform drug compositon
US4866046A (en) * 1988-05-31 1989-09-12 Top Laboratories, Inc. Low-dosage sublingual aspirin
HU201869B (en) * 1988-12-30 1991-01-28 Egyt Gyogyszervegyeszeti Gyar Process for producing microcapsules of quick dissolving active component
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
US5464632C1 (en) 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
JP3069458B2 (ja) * 1992-01-29 2000-07-24 武田薬品工業株式会社 口腔内崩壊型錠剤およびその製造法
US5635210A (en) * 1994-02-03 1997-06-03 The Board Of Regents Of The University Of Oklahoma Method of making a rapidly dissolving tablet
ZA961018B (en) * 1995-02-08 1997-08-08 Yamanouchi Europ Bv Oral dosage-forms containing a beta-lactam antibiotic.
DE19530575A1 (de) * 1995-08-19 1997-02-20 Gruenenthal Gmbh Schnell zerfallende Arzneiform von Tramadol oder einem Tramadolsalz
WO1997038679A2 (en) * 1996-04-16 1997-10-23 Novartis Consumer Health S.A. Fast disintegrating oral dosage form
RU2189227C2 (ru) * 1996-07-12 2002-09-20 Дайити Фармасьютикал Ко., Лтд. Быстро распадающиеся прессованные в формах материалы и способ их получения
US5869098A (en) * 1997-08-20 1999-02-09 Fuisz Technologies Ltd. Fast-dissolving comestible units formed under high-speed/high-pressure conditions

Also Published As

Publication number Publication date
EP1058538B2 (en) 2012-04-11
KR20010041609A (ko) 2001-05-25
CA2322315A1 (en) 1999-09-10
AU2727799A (en) 1999-09-20
EP1058538A1 (en) 2000-12-13
DE69901938T3 (de) 2012-08-02
EP1058538B9 (en) 2013-01-02
JP2002505269A (ja) 2002-02-19
NZ507271A (en) 2003-03-28
DE69901938T2 (de) 2002-10-10
DE69901938D1 (de) 2002-08-01
WO1999044580A1 (en) 1999-09-10
BR9908438A (pt) 2000-10-31
CA2322315C (en) 2008-09-16
AU741992B2 (en) 2001-12-13
AR018143A1 (es) 2001-10-31
DK1058538T3 (da) 2002-10-21
US6596311B1 (en) 2003-07-22
ATE219658T1 (de) 2002-07-15
EP1058538B1 (en) 2002-06-26
ES2178876T5 (es) 2012-10-01
PT1058538E (pt) 2002-11-29

Similar Documents

Publication Publication Date Title
ATE232091T1 (de) Orale pharmazeutische zusammensetzungen mit verzögerter freisetzung von reversiblen protonpumpen-inhibitoren
NZ507271A (en) Fast disintegrating tablets
IT1310485B1 (it) Dispositivo per l' alimentazione di compresse e simili in una macchina confezionatrice.
AU2003297260A1 (en) Fast-disintegrating solid dosage forms being not friable and comprising pullulan
LU92024I2 (fr) Pasireotide et ses dérivés pharmaceutiquement acceptables (SIGNIFOR)
TR200103493T2 (tr) Metaloproteaz önleyicileri
DK0814839T3 (da) Orale, farmaceutiske doseringsformer omfattende en protonpumpeinhibitor og et NSAID
LU92381I2 (fr) Macitentan et ses dérivés pharmaceutiquement acceptables (OPSUMIT)
DE60215787D1 (de) Behandlung von typ ii diabetes mit dipeptidyl-peptidase-iv-hemmern
NO20001042L (no) Oftalmiske preparater med forsinket frigivelse inneholdende vannoppløselige medikamenter
IT1276689B1 (it) Forma farmaceutica solida ad uso orale
TR199800815A2 (en) S�lfonilaminokarbonasitler.
TR200102977T2 (tr) Yeni tedavi yöntemi.
IS2259B (is) Aðferð til meðferðar á netjuhersli með notkun mótlyfs við integríninu alfa-4 undireiningunni
EA200200207A1 (ru) Применение антагонистов cgrp и ингибиторов высвобождения cgrp для устранения приливов в период менопаузы
ID28510A (id) Formulasi oral yang baru untuk agonis atau antagonis 5-ht4
NO994431L (no) Ny formulering
IT1310483B1 (it) Dispositivo per l' alimentazione di compresse e simili in una macchina confezionatrice.
ATE254851T1 (de) Iod-herstellungszusammensetzung
ATE401084T1 (de) Torasemid enthaltende lagerstabile pharmazeutische zubereitungen
SE0001916D0 (sv) Novel formulation
BR9909529A (pt) Maleato de paroxetina
ATE397447T1 (de) Feste paroxetin enthaltende zubereitungen
CR8948A (es) Composicion farmaceutica
CO5271688A1 (es) Uso de inhibidor de secrecion de apoliproteinas b y/o de proteina de transferencia de trigliceridos microsmales