ES2179517T3 - Procedimiento para la obtencion de 2,4,5-trifluor-benzonitrilo. - Google Patents
Procedimiento para la obtencion de 2,4,5-trifluor-benzonitrilo.Info
- Publication number
- ES2179517T3 ES2179517T3 ES98932174T ES98932174T ES2179517T3 ES 2179517 T3 ES2179517 T3 ES 2179517T3 ES 98932174 T ES98932174 T ES 98932174T ES 98932174 T ES98932174 T ES 98932174T ES 2179517 T3 ES2179517 T3 ES 2179517T3
- Authority
- ES
- Spain
- Prior art keywords
- trifluor
- benzonitrile
- procedure
- obtaining
- diluent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- DLKNOGQOOZFICZ-UHFFFAOYSA-N 2,4,5-trifluorobenzonitrile Chemical compound FC1=CC(F)=C(C#N)C=C1F DLKNOGQOOZFICZ-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000003085 diluting agent Substances 0.000 abstract 2
- QMYVWJVVVMIBMM-UHFFFAOYSA-N 2,4,5-trifluoroaniline Chemical compound NC1=CC(F)=C(F)C=C1F QMYVWJVVVMIBMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal cyanide Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000009935 nitrosation Effects 0.000 abstract 1
- 238000007034 nitrosation reaction Methods 0.000 abstract 1
- 239000003352 sequestering agent Substances 0.000 abstract 1
- 150000003623 transition metal compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
La invención se refiere a un procedimiento para la producción de 2,4,5-trifluorobenzonitrilo de fórmula (I), que comprende las siguientes etapas: A) hacer reaccionar 2,4,5-trifluoroanilina de fórmula (II) con un agente de nitrosación en presencia de un diluyente, y B) hacer reaccionar el producto de la etapa A) con un cianuro de metal alcalino en presencia de un compuesto de metal de transición, un secuestrante de ácido y un diluyente.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19727890A DE19727890A1 (de) | 1997-07-01 | 1997-07-01 | Verfahren zur Herstellung von 2,4,5-Trifluor-benzonitril |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2179517T3 true ES2179517T3 (es) | 2003-01-16 |
Family
ID=7834188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98932174T Expired - Lifetime ES2179517T3 (es) | 1997-07-01 | 1998-06-18 | Procedimiento para la obtencion de 2,4,5-trifluor-benzonitrilo. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6399807B1 (es) |
| EP (1) | EP0994849B1 (es) |
| JP (1) | JP2002507218A (es) |
| CN (1) | CN1144780C (es) |
| AU (1) | AU8216798A (es) |
| BR (1) | BR9810647A (es) |
| DE (2) | DE19727890A1 (es) |
| DK (1) | DK0994849T3 (es) |
| ES (1) | ES2179517T3 (es) |
| IL (1) | IL133130A (es) |
| WO (1) | WO1999001425A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4118065A4 (en) * | 2020-03-12 | 2024-04-17 | Aarti Industries Limited | Process for the preparation of 1-bromo-2,4,5-trifluorobenzene |
| CN117466729A (zh) * | 2023-12-28 | 2024-01-30 | 山东国邦药业有限公司 | 一种2,4,5-三氟苯乙酸的合成方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2044015A (en) * | 1936-06-16 | Benzonitriles and process for | ||
| NL104318C (es) | 1959-04-28 | |||
| GB1131501A (en) | 1965-05-24 | 1968-10-23 | Imp Smelting Corp Ltd | Fluorinated quinolines |
| DE3576335D1 (de) | 1984-12-14 | 1990-04-12 | Daiichi Seiyaku Co | Chinolincarbonsaeure-derivate. |
| FR2632648A1 (fr) | 1988-06-14 | 1989-12-15 | Thomson Csf | Polymeres mesomorphes a chaines laterales a forte anisotropie dielectrique utilisables en optique non lineaire |
| DE4238125A1 (de) | 1992-11-12 | 1994-05-19 | Bayer Ag | Substituierte Triazolinone |
| GB8919678D0 (en) | 1989-08-31 | 1989-10-11 | Ici Plc | Fluorobenzene derivatives |
| CH680056A5 (es) | 1989-12-11 | 1992-06-15 | Bruderer Ag | |
| FR2655648B1 (fr) | 1989-12-11 | 1992-03-13 | Isochem Sa | Dichloro-2,4-fluoro-5-benzonitrile et procedes pour sa preparation, son application a la preparation de l'acide chloro-2-difluoro-4,5-benzouique et nouveau procede de preparation. |
| EP0497239A1 (de) | 1991-01-30 | 1992-08-05 | Hoechst Aktiengesellschaft | 2-Chlor-4,5-difluorbenzonitril und Verfahren zu seiner Herstellung |
| DE59309216D1 (de) | 1992-02-26 | 1999-01-28 | Clariant Gmbh | Verfahren zur Herstellung von 2,4,5-Trifluorbenzonitril |
| GB9208123D0 (en) | 1992-04-13 | 1992-05-27 | Ici Plc | Substituted fluorobenzenes |
| GB9223195D0 (en) * | 1992-11-05 | 1992-12-16 | Octel Chem Ltd | Preparation of substituted aryl compounds |
| DE4309966A1 (de) | 1993-03-26 | 1994-09-29 | Bayer Ag | Substituierte 1-Aryltriazolinone |
| EP0635486B1 (de) | 1993-07-21 | 1998-12-09 | Clariant GmbH | Verfahren zur Herstellung von Fluorbenzonitrilen |
| DE4339863A1 (de) | 1993-11-23 | 1995-05-24 | Bayer Ag | Substituierte Carbamoyltriazole |
| DE4416329A1 (de) | 1994-05-09 | 1995-11-16 | Hoechst Ag | Substituierte 2-Chlor-3,4,5-trifluorbenzole und ein Verfahren zu ihrer Herstellung |
-
1997
- 1997-07-01 DE DE19727890A patent/DE19727890A1/de not_active Withdrawn
-
1998
- 1998-06-18 US US09/446,491 patent/US6399807B1/en not_active Expired - Fee Related
- 1998-06-18 DE DE59805434T patent/DE59805434D1/de not_active Expired - Fee Related
- 1998-06-18 IL IL13313098A patent/IL133130A/en not_active IP Right Cessation
- 1998-06-18 WO PCT/EP1998/003732 patent/WO1999001425A1/de not_active Ceased
- 1998-06-18 AU AU82167/98A patent/AU8216798A/en not_active Abandoned
- 1998-06-18 ES ES98932174T patent/ES2179517T3/es not_active Expired - Lifetime
- 1998-06-18 JP JP50623699A patent/JP2002507218A/ja active Pending
- 1998-06-18 EP EP98932174A patent/EP0994849B1/de not_active Expired - Lifetime
- 1998-06-18 DK DK98932174T patent/DK0994849T3/da active
- 1998-06-18 CN CNB988068192A patent/CN1144780C/zh not_active Expired - Fee Related
- 1998-06-18 BR BR9810647-3A patent/BR9810647A/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL133130A0 (en) | 2001-03-19 |
| HK1029577A1 (en) | 2001-04-06 |
| EP0994849B1 (de) | 2002-09-04 |
| US6399807B1 (en) | 2002-06-04 |
| DK0994849T3 (da) | 2002-11-25 |
| BR9810647A (pt) | 2000-08-01 |
| IL133130A (en) | 2004-06-20 |
| EP0994849A1 (de) | 2000-04-26 |
| JP2002507218A (ja) | 2002-03-05 |
| DE59805434D1 (de) | 2002-10-10 |
| WO1999001425A1 (de) | 1999-01-14 |
| CN1261875A (zh) | 2000-08-02 |
| DE19727890A1 (de) | 1999-01-07 |
| CN1144780C (zh) | 2004-04-07 |
| AU8216798A (en) | 1999-01-25 |
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