ES2180926T3 - Procedimiento para la preparacion de 2-halometil-penem y su uso en la preparacion de penem antibacterianos. - Google Patents

Procedimiento para la preparacion de 2-halometil-penem y su uso en la preparacion de penem antibacterianos.

Info

Publication number
ES2180926T3
ES2180926T3 ES97903325T ES97903325T ES2180926T3 ES 2180926 T3 ES2180926 T3 ES 2180926T3 ES 97903325 T ES97903325 T ES 97903325T ES 97903325 T ES97903325 T ES 97903325T ES 2180926 T3 ES2180926 T3 ES 2180926T3
Authority
ES
Spain
Prior art keywords
preparation
penem
procedure
halometil
antibacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97903325T
Other languages
English (en)
Inventor
Enzo Perrotta
Maria Altamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Luso Farmaco dItalia SpA
A Menarini Industrie Farmaceutiche Riunite SRL
Original Assignee
Istituto Luso Farmaco dItalia SpA
A Menarini Industrie Farmaceutiche Riunite SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Luso Farmaco dItalia SpA, A Menarini Industrie Farmaceutiche Riunite SRL filed Critical Istituto Luso Farmaco dItalia SpA
Application granted granted Critical
Publication of ES2180926T3 publication Critical patent/ES2180926T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO DE PREPARACION DE 2 - HALOMETIL - PENEMS (ESPECIALMENTE 2 - CLOROMETIL - PENEMS), QUE COMPRENDE, COMO FASE INTERMEDIA, LA FORMACION DE LA CORRESPONDIENTE 2 - HALOACETILTIO - AZETIDONA.
ES97903325T 1996-02-27 1997-02-19 Procedimiento para la preparacion de 2-halometil-penem y su uso en la preparacion de penem antibacterianos. Expired - Lifetime ES2180926T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96FI000033A IT1286558B1 (it) 1996-02-27 1996-02-27 Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici

Publications (1)

Publication Number Publication Date
ES2180926T3 true ES2180926T3 (es) 2003-02-16

Family

ID=11351505

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97903325T Expired - Lifetime ES2180926T3 (es) 1996-02-27 1997-02-19 Procedimiento para la preparacion de 2-halometil-penem y su uso en la preparacion de penem antibacterianos.

Country Status (12)

Country Link
US (1) US6153747A (es)
EP (1) EP0883620B1 (es)
CN (1) CN1116298C (es)
AU (1) AU1792397A (es)
CA (1) CA2247269A1 (es)
DE (1) DE69715158T2 (es)
ES (1) ES2180926T3 (es)
IT (1) IT1286558B1 (es)
PL (1) PL328435A1 (es)
RU (1) RU2175971C2 (es)
WO (1) WO1997031922A1 (es)
ZA (1) ZA971471B (es)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL192265C (nl) * 1979-02-24 1997-04-03 Erba Carlo Spa Penemcarbonzuur-verbindingen en farmaceutische preparaten die deze verbindingen bevatten.
GB2118181B (en) * 1982-04-08 1986-07-30 Erba Farmitalia Substituted penem derivatives and new process for their preparation
US4794109A (en) * 1982-11-16 1988-12-27 Ciba-Geigy Corporation 6-hydroxy-lower alkylpenem compounds, pharmaceutical preparations that contain these compounds, and the use of the latter
JPS59152387A (ja) * 1983-02-10 1984-08-31 Shionogi & Co Ltd 新規ペネム化合物
GB8321677D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia Preparation of penems
EP0399228A1 (de) * 1989-04-29 1990-11-28 Hoechst Aktiengesellschaft Verfahren zur Herstellung von Penemverbindungen
GB8915392D0 (en) * 1989-07-05 1989-08-23 Erba Carlo Spa Process for penems
GB9110507D0 (en) * 1991-05-15 1991-07-03 Smithkline Beecham Plc Chemical compounds
EP0597401A3 (en) * 1992-11-11 1995-07-26 Takeda Chemical Industries Ltd Preparation of penemes.

Also Published As

Publication number Publication date
EP0883620B1 (en) 2002-09-04
WO1997031922A1 (en) 1997-09-04
ITFI960033A1 (it) 1997-08-27
DE69715158T2 (de) 2003-05-15
DE69715158D1 (de) 2002-10-10
US6153747A (en) 2000-11-28
ITFI960033A0 (it) 1996-02-27
IT1286558B1 (it) 1998-07-15
ZA971471B (en) 1997-09-04
CA2247269A1 (en) 1997-09-04
AU1792397A (en) 1997-09-16
CN1211988A (zh) 1999-03-24
EP0883620A1 (en) 1998-12-16
PL328435A1 (en) 1999-02-01
RU2175971C2 (ru) 2001-11-20
CN1116298C (zh) 2003-07-30

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