ES2180942T3 - Redes de polimeros biodegradables para su uso en aplicaciones ortopedicas y dentales. - Google Patents

Redes de polimeros biodegradables para su uso en aplicaciones ortopedicas y dentales.

Info

Publication number
ES2180942T3
ES2180942T3 ES97906686T ES97906686T ES2180942T3 ES 2180942 T3 ES2180942 T3 ES 2180942T3 ES 97906686 T ES97906686 T ES 97906686T ES 97906686 T ES97906686 T ES 97906686T ES 2180942 T3 ES2180942 T3 ES 2180942T3
Authority
ES
Spain
Prior art keywords
cross
orthopedic
anhydride prepolymers
irradiation
linked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97906686T
Other languages
English (en)
Inventor
Kristi S Anseth
Robert S Langer
Venkatram R Shastri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Application granted granted Critical
Publication of ES2180942T3 publication Critical patent/ES2180942T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0042—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F267/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated polycarboxylic acids or derivatives thereof as defined in group C08F22/00
    • C08F267/02—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated polycarboxylic acids or derivatives thereof as defined in group C08F22/00 on to polymers of acids or salts

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Surgical Instruments (AREA)
  • Polymerisation Methods In General (AREA)

Abstract

LA INVENCION SE REFIERE A RETICULAS POLIMERICAS BIODEGRADABLES, UTILES PARA DIVERSAS APLICACIONES ORTOPEDICAS Y DENTALES. DICHAS RETICULAS SE PUEDEN FORMAR, EN UNA REALIZACION DE LA INVENCION, MEDIANTE POLIMERIZACION DE PRECURSORES POLIMERICOS DE ANHIDRIDOS QUE INCLUYEN GRUPOS RETICULABLES, COMO FRACCIONES INSATURADAS. DICHOS PRECURSORES SE PUEDEN RETICULAR, POR EJEMPLO A TRAVES DE UNA REACCION DE FOTOPOLIMERIZACION, MEDIANTE IRRADIACION DEL PRECURSOR CON LUZ, EN PRESENCIA DE UN INICIADOR RADICALAR. LOS PRECURSORES DE ANHIDRIDOS ADECUADOS INCLUYEN DIANHIDRIDOS DE UN ACIDO DICARBOXILICO Y DE ACIDO CARBOXILICO QUE COMPRENDEN UN GRUPO RETICULABLE. POR EJEMPLO, SE PUEDEN UTILIZAR DIANHIDRIDOS DE ACIDO METACRILICO DE MONOMEROS U OLIGOMEROS DE UN DIACIDO, COMO EL ACIDO SEBACICO O 1, 3 - BIS (P- CARBOXIFENOXI) - HEXANO. LOS PRECURSORES POLIMERICOS DE ANHIDRIDO SE PUEDEN APLICAR IN VIVO A UN LUGAR EN EL QUE SE PRECISA UN IMPLANTE ORTOPEDICO Y SE PUEDEN RETICULAR A CONTINUACION MEDIANTE IRRADIACIONCON LUZ UV, PARA FORMAR UN IMPLANTE BIODEGRADABLE, COMO UNA VARILLA, CLAVO O PLACA. LOS IMPLANTES PROPORCIONAN VENTAJOSAMENTE UN SOPORTE MECANICO Y SON CAPACES ASIMISMO DE EXPERIMENTAR UNA DEGRADACION SUPERFICIAL LENTA, PERMITIENDO EL CRECIMIENTO INTERNO DEL HUESO.
ES97906686T 1996-02-20 1997-02-19 Redes de polimeros biodegradables para su uso en aplicaciones ortopedicas y dentales. Expired - Lifetime ES2180942T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60317196A 1996-02-20 1996-02-20

Publications (1)

Publication Number Publication Date
ES2180942T3 true ES2180942T3 (es) 2003-02-16

Family

ID=24414369

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97906686T Expired - Lifetime ES2180942T3 (es) 1996-02-20 1997-02-19 Redes de polimeros biodegradables para su uso en aplicaciones ortopedicas y dentales.

Country Status (9)

Country Link
EP (1) EP0882085B1 (es)
JP (2) JP3599749B2 (es)
AT (1) ATE221093T1 (es)
CA (1) CA2246615C (es)
DE (1) DE69714216T2 (es)
DK (1) DK0882085T3 (es)
ES (1) ES2180942T3 (es)
PT (1) PT882085E (es)
WO (1) WO1997030104A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060177416A1 (en) 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
JP4110920B2 (ja) 2002-10-25 2008-07-02 トヨタ自動車株式会社 電磁駆動弁装置
US7393493B2 (en) * 2003-02-27 2008-07-01 A Enterprises, Inc. Crosslinkable polymeric materials and their applications
EP1926780B1 (en) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
EP2170355A1 (en) * 2007-03-30 2010-04-07 Medivas, LLC Bioabsorbable elastomeric polymer networks, cross-linkers and methods of use
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
CA2839526A1 (en) 2011-06-23 2012-12-27 Dsm Ip Assets B.V. Micro- or nanoparticles comprising a biodegradable polyesteramide copolymer for use in the delivery of bioactive agents
CN107106509B (zh) 2014-12-18 2021-11-30 帝斯曼知识产权资产管理有限公司 用于递送酸敏感药物的药物递送系统
EP4058504A1 (en) 2019-11-12 2022-09-21 DSM IP Assets B.V. Polyesteramide copolymers possessing high glass transition temperatures

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1292338C (en) * 1985-01-29 1991-11-19 Dentsply International Inc. Non-toxic organic compositions and calcium hydroxide compositions thereof
JPS6261908A (ja) * 1985-09-11 1987-03-18 G C Dental Ind Corp 歯科修復用光重合性組成物
DE3536077A1 (de) * 1985-10-09 1987-04-09 Muehlbauer Ernst Kg Polymerisierbare saeure und saeurederivate enthaltende verbindungen, dieselben enthaltende mischungen und ihre verwendung
US4789724A (en) * 1986-10-17 1988-12-06 Massachusetts Institute Of Technology Preparation of anhydride copolymers
US4857311A (en) * 1987-07-31 1989-08-15 Massachusetts Institute Of Technology Polyanhydrides with improved hydrolytic degradation properties
US5019379A (en) * 1987-07-31 1991-05-28 Massachusetts Institute Of Technology Unsaturated polyanhydrides
JPH01265967A (ja) * 1988-04-18 1989-10-24 Sanyo Chem Ind Ltd 光硬化性医療用樹脂組成物
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5236563A (en) * 1990-06-18 1993-08-17 Advanced Surface Technology Inc. Surface-modified bioabsorbables

Also Published As

Publication number Publication date
PT882085E (pt) 2002-12-31
JP3599749B2 (ja) 2004-12-08
EP0882085A1 (en) 1998-12-09
JP2000507999A (ja) 2000-06-27
DK0882085T3 (da) 2002-10-28
ATE221093T1 (de) 2002-08-15
EP0882085B1 (en) 2002-07-24
CA2246615C (en) 2006-05-09
JP4460345B2 (ja) 2010-05-12
JP2004321795A (ja) 2004-11-18
WO1997030104A1 (en) 1997-08-21
DE69714216D1 (de) 2002-08-29
CA2246615A1 (en) 1997-08-21
DE69714216T2 (de) 2003-03-27

Similar Documents

Publication Publication Date Title
US5902599A (en) Biodegradable polymer networks for use in orthopedic and dental applications
Fisher et al. Photocrosslinking characteristics and mechanical properties of diethyl fumarate/poly (propylene fumarate) biomaterials
Jo et al. Synthesis of poly (ethylene glycol)-tethered poly (propylene fumarate) and its modification with GRGD peptide
CA2323925C (en) Crosslinkable macromers bearing initiator groups
AU2002345943B2 (en) Photocrosslinking of diethyl fumarate/poly(propylene fumarate) biomaterials
ES2180942T3 (es) Redes de polimeros biodegradables para su uso en aplicaciones ortopedicas y dentales.
ATE275986T1 (de) Memory-thermoplaste und polymernetzwerke zum gewebeaufbau
US20060257629A1 (en) Photosensitive polymeric networks
CA2296374A1 (en) Semi-interpenetrating polymer networks
NO20012315D0 (no) Fornettede hyluronsyrer og medisinske anvendelser derav
DK0991701T3 (da) Hydrofilt overtræk og fremgangsmåde til fremstilling deraf
DK0627911T3 (da) Fotopolymeriserbare bionedbrydelige hydrogeler somvævskontaktmaterialer og bærere med reguleret frigivelse
KR20210016331A (ko) 생체 재료용 3d 프린팅 조성물
Shung et al. Crosslinking characteristics of and cell adhesion to an injectable poly (propylene fumarate-co-ethylene glycol) hydrogel using a water-soluble crosslinking system
Ho et al. Synthesis, polymerisation and degradation of poly (lactide-co-propylene glycol) dimethacrylate adhesives
WO1997030104B1 (en) Biodegradable polymer networks for use in orthopedic and dental applications
Kopeček et al. Biological tolerance of poly (N‐substituted acrylamides)
DE59807763D1 (de) Verfahren zur herstellung kationischer polyelektrolyte
TW327678B (en) A soft contact lens comprising anti-bacterial, insoluble, metal-chelating polymers the invention relates to a soft contact lens comprising a water-swollen gel of an anti-bacterial, insoluble, metal-chelating polymer of a special composition.
CA2205717A1 (en) Biodegradable poly(amino acid)s derivatized amino acid polymers and methods for making same
Sharifi et al. Photopolymerization and shrinkage kinetics of in situ crosslinkable N‐vinyl‐pyrrolidone/poly (ε‐caprolactone fumarate) networks
WO2002015848A3 (en) Dental restorative compositions and method of use thereof
DE59503555D1 (de) Ein- oder mehrstufiges Verfahren zur Herstellung niedrigviskoser, wasserlöslicher Polymerdispersionen
BR9510286A (pt) Adjuvante para vacinas vacina utilização de um polímero e processo para preparar uma vacina
JP2009119287A (ja) 整形外科および歯科用途での使用のための生分解性ポリマーネットワーク