ES2181771T3 - Composiciones de inhibina y metodo para el uso de la misma. - Google Patents
Composiciones de inhibina y metodo para el uso de la misma.Info
- Publication number
- ES2181771T3 ES2181771T3 ES95913576T ES95913576T ES2181771T3 ES 2181771 T3 ES2181771 T3 ES 2181771T3 ES 95913576 T ES95913576 T ES 95913576T ES 95913576 T ES95913576 T ES 95913576T ES 2181771 T3 ES2181771 T3 ES 2181771T3
- Authority
- ES
- Spain
- Prior art keywords
- protein
- heterological
- inhibine
- heterology
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Confectionery (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- General Preparation And Processing Of Foods (AREA)
- Non-Alcoholic Beverages (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Dental Preparations (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UN METODO PARA ACELERAR LA APARICION DE LA PUBERTAD EN AVIARES, ESPECIALMENTE EN RATITAS Y PSITACIFORMES, MEDIANTE LA ADMINISTRACION DE UNA PROTEINA HETEROLOGA QUE CONTENGA INHIBINA, O UN FRAGMENTO DE LA MISMA, Y UNA PROTEINA DE SOPORTE. LA PRESENTE INVENCION TAMBIEN SE REFIERE A UN METODO PARA AUMENTAR LA PRODUCCION DE HUEVOS EN ANIMALES, EN PARTICULAR PAJAROS, PARTICULARMENTE RATITAS, MEDIANTE LA ADMINISTRACION DE LA PROTEINA HETEROLOGA. ESTA INVENCION TAMBIEN SE REFIERE A LA PROTEINA HETEROLOGA Y A UN METODO PARA LA PRODUCCION DE LA PROTEINA HETEROLOGA. LA PROTEINA HETEROLOGA PUEDE SER BIEN INHIBINA CONJUGADA A LA PROTEINA DE SOPORTE O INHIBINA FUSIONADA A LA PROTEINA DE SOPORTE. EL METODO PARA LA PRODUCCION DE LA PROTEINA HETEROLOGA FUSIONADA CONSISTE EN INSERTAR UNA INHIBINA QUE CODIFICA UN CADN DE DOBLE CEPA, O UN FRAGMENTO DE LA MISMA, EN UN VECTOR QUE CODIFICA UNA PROTEINA DE SOPORTE TAL COMO UNA PROTEINA QUE SE ENLAZA A LA MALTOSA O ALBUMINA DEL SUERO BOVINO. TRAS INSERTAR EL VECTOR EN UN SISTEMA DE EXPRESION, EL SISTEMA EXPRESA LA PROTEINA HETEROLOGA FUSIONADA. TRAS PURIFICAR LA PROTEINA HETEROLOGA EXPRESADA, SE ADMINISTRA UNA CANTIDAD EFECTIVA DE LA PROTEINA A UN ANIMAL DE MODO QUE SE PRODUZCA UNA RESPUESTA INMUNOLOGICA EN EL ANIMAL CONTRA LA PROTEINA HETEROLOGA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20296494A | 1994-02-28 | 1994-02-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2181771T3 true ES2181771T3 (es) | 2003-03-01 |
Family
ID=22751927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95913576T Expired - Lifetime ES2181771T3 (es) | 1994-02-28 | 1995-02-28 | Composiciones de inhibina y metodo para el uso de la misma. |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0804219B1 (es) |
| JP (1) | JPH09510702A (es) |
| CN (1) | CN1149258A (es) |
| AT (1) | ATE220554T1 (es) |
| AU (1) | AU704737B2 (es) |
| BR (1) | BR9507426A (es) |
| CA (1) | CA2184183C (es) |
| DE (1) | DE69527439T2 (es) |
| DK (1) | DK0804219T3 (es) |
| ES (1) | ES2181771T3 (es) |
| FI (1) | FI963325L (es) |
| MX (1) | MX9603702A (es) |
| NO (1) | NO963572L (es) |
| NZ (1) | NZ282981A (es) |
| PL (1) | PL184202B1 (es) |
| PT (1) | PT804219E (es) |
| RU (1) | RU2170100C2 (es) |
| WO (1) | WO1995022980A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5786179A (en) * | 1994-02-28 | 1998-07-28 | Agritech Technologies Ltd. | Heterologous protein comprising avian alpha-subunit inhibin protein and methods of producing same |
| US5725858A (en) * | 1994-02-28 | 1998-03-10 | Agritech Technologies, Ltd. | Methods of enhancing production performance of birds comprising administration of heterologous protein comprising avian alpha-subunit inhibin protein |
| BR0316084A (pt) * | 2002-11-07 | 2005-09-27 | Agritech Technology Ltd | Composições peptìdicas antigênicas múltiplas relacionadas com a inibina que melhoram o desempenho da produção avìcola. |
| EP3470072A1 (en) | 2005-06-23 | 2019-04-17 | Biogen MA Inc. | Compositions and methods for modulation of smn2 splicing |
| AU2006285850A1 (en) | 2005-08-29 | 2007-03-08 | Japan Science And Technology Agency | Antibody produced using ostrich and method for production thereof |
| ES2699827T3 (es) | 2009-06-17 | 2019-02-13 | Biogen Ma Inc | Composiciones y métodos para la modulación de corte y empalme de SMN2 en un sujeto |
| WO2014110291A1 (en) | 2013-01-09 | 2014-07-17 | Isis Pharmaceuticals, Inc. | Compositions and methods for modulation of smn2 splicing in a subject |
| BR102014005376A2 (pt) * | 2014-03-07 | 2016-02-10 | Ouro Fino Saúde Animal Ltda | antígeno de inibina alfa, gene codificante de inibina alfa, gene codificante de proteína de fusão, processo de obtenção do antígeno de inibina alfa, composição antigênica, uso do antígeno de inibina alfa e uso da composição antigênica |
| EP3797780B1 (en) | 2014-04-17 | 2022-09-14 | Biogen MA Inc. | Compositions and methods for modulation of smn2 splicing in a subject |
| US10436802B2 (en) | 2014-09-12 | 2019-10-08 | Biogen Ma Inc. | Methods for treating spinal muscular atrophy |
| US11198867B2 (en) | 2016-06-16 | 2021-12-14 | Ionis Pharmaceuticals, Inc. | Combinations for the modulation of SMN expression |
| CN110551744A (zh) * | 2019-09-18 | 2019-12-10 | 普健生物（武汉）科技有限公司 | 一种人抑制素a的核苷酸序列及重组表达人抑制素a的方法 |
| CN120505310A (zh) | 2020-02-28 | 2025-08-19 | Ionis制药公司 | 用于调节smn2的化合物和方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089396A (en) * | 1985-10-03 | 1992-02-18 | Genentech, Inc. | Nucleic acid encoding β chain prodomains of inhibin and method for synthesizing polypeptides using such nucleic acid |
| US4864019A (en) * | 1985-11-08 | 1989-09-05 | The Salk Institute For Biological Studies | Antibodies to inhibin and conjugates produced therefrom |
-
1995
- 1995-02-28 DE DE69527439T patent/DE69527439T2/de not_active Expired - Fee Related
- 1995-02-28 CN CN95192317A patent/CN1149258A/zh active Pending
- 1995-02-28 AU AU20959/95A patent/AU704737B2/en not_active Ceased
- 1995-02-28 NZ NZ282981A patent/NZ282981A/en unknown
- 1995-02-28 DK DK95913576T patent/DK0804219T3/da active
- 1995-02-28 MX MX9603702A patent/MX9603702A/es not_active IP Right Cessation
- 1995-02-28 EP EP95913576A patent/EP0804219B1/en not_active Expired - Lifetime
- 1995-02-28 AT AT95913576T patent/ATE220554T1/de not_active IP Right Cessation
- 1995-02-28 PT PT95913576T patent/PT804219E/pt unknown
- 1995-02-28 PL PL95316628A patent/PL184202B1/pl not_active IP Right Cessation
- 1995-02-28 ES ES95913576T patent/ES2181771T3/es not_active Expired - Lifetime
- 1995-02-28 RU RU96119774/13A patent/RU2170100C2/ru not_active IP Right Cessation
- 1995-02-28 WO PCT/US1995/002795 patent/WO1995022980A1/en not_active Ceased
- 1995-02-28 BR BR9507426A patent/BR9507426A/pt not_active IP Right Cessation
- 1995-02-28 CA CA002184183A patent/CA2184183C/en not_active Expired - Fee Related
- 1995-02-28 JP JP7522532A patent/JPH09510702A/ja not_active Withdrawn
- 1995-02-28 FI FI963325A patent/FI963325L/fi not_active Application Discontinuation
-
1996
- 1996-08-27 NO NO963572A patent/NO963572L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69527439D1 (de) | 2002-08-22 |
| PL316628A1 (en) | 1997-02-03 |
| ATE220554T1 (de) | 2002-08-15 |
| CA2184183C (en) | 2005-02-08 |
| NO963572D0 (no) | 1996-08-27 |
| CA2184183A1 (en) | 1995-08-31 |
| AU2095995A (en) | 1995-09-11 |
| EP0804219A4 (en) | 1999-02-24 |
| PT804219E (pt) | 2002-12-31 |
| FI963325A7 (fi) | 1996-10-21 |
| CN1149258A (zh) | 1997-05-07 |
| BR9507426A (pt) | 1997-09-16 |
| FI963325L (fi) | 1996-10-21 |
| FI963325A0 (fi) | 1996-08-27 |
| PL184202B1 (pl) | 2002-09-30 |
| AU704737B2 (en) | 1999-05-06 |
| NZ282981A (en) | 1998-08-26 |
| NO963572L (no) | 1996-10-25 |
| JPH09510702A (ja) | 1997-10-28 |
| RU2170100C2 (ru) | 2001-07-10 |
| DK0804219T3 (da) | 2002-11-11 |
| MX9603702A (es) | 1997-12-31 |
| EP0804219A1 (en) | 1997-11-05 |
| EP0804219B1 (en) | 2002-07-17 |
| WO1995022980A1 (en) | 1995-08-31 |
| DE69527439T2 (de) | 2003-02-20 |
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