ES2183148T3 - Composiciones oftalmicas que contienen un inhibidor de anhidrasa carbonica y de la goma de xantano. - Google Patents

Composiciones oftalmicas que contienen un inhibidor de anhidrasa carbonica y de la goma de xantano.

Info

Publication number
ES2183148T3
ES2183148T3 ES97911223T ES97911223T ES2183148T3 ES 2183148 T3 ES2183148 T3 ES 2183148T3 ES 97911223 T ES97911223 T ES 97911223T ES 97911223 T ES97911223 T ES 97911223T ES 2183148 T3 ES2183148 T3 ES 2183148T3
Authority
ES
Spain
Prior art keywords
anhydration
inhibitor
xantano
gum
carbon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97911223T
Other languages
English (en)
Inventor
Gilles Chastaing
Bernard Plazonnet
Annouk Rozier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Merck Sharp and Dohme Chibret SAS
Original Assignee
Laboratories Merck Sharp and Dohme Chibret SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratories Merck Sharp and Dohme Chibret SAS filed Critical Laboratories Merck Sharp and Dohme Chibret SAS
Application granted granted Critical
Publication of ES2183148T3 publication Critical patent/ES2183148T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

COMPOSICIONES OFTALMICAS USADAS PARA TRATAR LA HIPERTENSION OCULAR Y EL GLAUCOMA. ESTAS COMPOSICIONES INCLUYEN UNA SOLUCION HIPOTONICA DE 1,1 A 0,2% (EN PESO) DE GOMA DE XANTANO Y DE 0,5 A 5% (EN PESO) DE UN INHIBIDOR DE ANHIDRASA CARBONICA TOPICA O DE UNA DE SUS SALES OFTALMOLOGICAMENTE ACEPTABLES.
ES97911223T 1996-10-17 1997-10-09 Composiciones oftalmicas que contienen un inhibidor de anhidrasa carbonica y de la goma de xantano. Expired - Lifetime ES2183148T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9612658A FR2754712B1 (fr) 1996-10-17 1996-10-17 Compositions ophtalmiques

Publications (1)

Publication Number Publication Date
ES2183148T3 true ES2183148T3 (es) 2003-03-16

Family

ID=9496748

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97911223T Expired - Lifetime ES2183148T3 (es) 1996-10-17 1997-10-09 Composiciones oftalmicas que contienen un inhibidor de anhidrasa carbonica y de la goma de xantano.

Country Status (13)

Country Link
US (1) US6264935B1 (es)
EP (1) EP0932389B1 (es)
JP (1) JP2001508035A (es)
AT (1) ATE223200T1 (es)
AU (1) AU715223B2 (es)
CA (1) CA2269552A1 (es)
DE (1) DE69715228T2 (es)
ES (1) ES2183148T3 (es)
FR (1) FR2754712B1 (es)
HR (1) HRP970552A2 (es)
PE (1) PE106998A1 (es)
WO (1) WO1998017249A1 (es)
ZA (1) ZA979219B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6174524B1 (en) 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
US6261547B1 (en) 1998-04-07 2001-07-17 Alcon Manufacturing, Ltd. Gelling ophthalmic compositions containing xanthan gum
JP2003513046A (ja) 1999-11-01 2003-04-08 アルコン，インコーポレイテッド フルオロキノロン抗生薬およびキサンタンガムを含有する薬学的組成物
AU2001270593A1 (en) 2000-07-28 2002-02-13 Alcon Universal Ltd. Pharmaceutical compositions containing tobramycin and xanthan gum
US20040067992A1 (en) * 2001-08-10 2004-04-08 Pharmacia Corporation Compositions of a cyclooxygenase-2 selective inhibitor and a carbonic anhydrase inhibitor for the treatment of neoplasia
PL373433A1 (en) * 2002-08-30 2005-08-22 Altana Pharma Ag The use of the combination of ciclesonide and antihistamines for the treatment of allergic rhinitis
PT1572217E (pt) * 2002-12-12 2008-11-28 Nycomed Gmbh Medicamento combinado de r,r-formoterol e ciclesonida
US8371292B2 (en) * 2003-09-16 2013-02-12 Nycomed Gmbh Use of ciclesonide for the treatment of respiratory diseases
AU2005235384B2 (en) * 2004-04-20 2010-09-09 Covis Pharma B.V. Use of ciclesonide for the treatment of respiratory diseases in a smoking patient
WO2006035969A1 (ja) * 2004-09-28 2006-04-06 Senju Pharmaceutical Co., Ltd. キサンタンガムおよびアミノ酸を含有する眼科用組成物
ES2337501T3 (es) * 2005-07-11 2010-04-26 Senju Pharmaceutical Co., Ltd. Preparacion oftalmica que comprende goma de xantano y terpenoide.
BRPI0620080A2 (pt) * 2005-12-19 2011-11-01 Comentis Inc formulações tópicas de mecamilamina para adminstração ocular e usos das mesma
WO2007108541A1 (ja) 2006-03-23 2007-09-27 Senju Pharmaceutical Co., Ltd. キサンタンガムおよびブドウ糖を含有する眼科用組成物
MX2009001037A (es) 2006-07-31 2009-05-15 Senju Pharma Co Preparacion liquida acuosa que contiene compuesto de amida.
WO2010004594A1 (en) * 2008-07-08 2010-01-14 S.I.F.I. Societa' Industria Farmaceutica Italiana S.P.A. Ophthalmic compositions for treating pathologies of the posterior segment of the eye
AU2014348620A1 (en) * 2013-11-15 2016-06-16 Teva Pharmaceutical Industries Ltd. Treatment of glaucoma using laquinimod
WO2016063184A1 (en) * 2014-10-20 2016-04-28 Sentiss Pharma Private Limited Ophthalmic solution
IT202000002296A1 (it) * 2020-02-06 2021-08-06 Sifi Spa Formulazioni topiche oftalmiche a base di xantano con ridotta posologia

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136173A (en) 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4136178A (en) 1977-01-31 1979-01-23 American Home Products Corp. Locust bean gum therapeutic compositions
US4136177A (en) 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
US5157044A (en) 1983-02-04 1992-10-20 University Of Iowa Research Foundation Analogs of carbonic anhydrase inhibitors and their use as topical IOP inhibitors
US4863922A (en) 1984-12-12 1989-09-05 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US4876271A (en) 1988-12-20 1989-10-24 Merck & Co., Inc. Substituted thieno[3,2-b]thiophene-2-sulfonamides as topically active carbonic anhydrase inhibitors
US4929549A (en) 1989-02-08 1990-05-29 Merck & Co., Inc. 5-carbamoylthieno[2,3-b]thiophene-2-sulfon-amides as topically active carbonic anhydrase inhibitors
US5120757A (en) 1989-07-31 1992-06-09 Merck & Co., Inc. Substituted aromatic sulfonamides as antiglaucoma agents
FR2657018A1 (fr) 1990-01-12 1991-07-19 Merck Sharp & Dohme Composition ophtalmique fluide a base de microparticules lipidiques contenant au moins un principe actif et son procede de preparation.
US5242937A (en) 1990-03-19 1993-09-07 Research Corporation Technologies, Inc. Topically active ocular thiadiazole sulfonamide carbonic anhydrase inhibitors
US5055480A (en) 1990-03-19 1991-10-08 Research Corporation Technologies, Inc. Topically active ocular gem-diacylthiadiazole sulfonamide carbonic anhydrase inhibitors
US5059613A (en) 1990-03-19 1991-10-22 Research Corporation Technologies, Inc. Topically active ocular benzothiazole sulfonamide carbonic anhydrase inhibitors
IE911192A1 (en) 1990-04-12 1991-10-23 Merck & Co Inc Substituted aromatic sulfonamides as antiglaucoma agents
CA2040460C (en) 1990-05-01 1997-06-10 Tacey X. Viegas Drug delivery with thermoreversible gels
US5091409A (en) 1990-05-17 1992-02-25 Merck & Co., Inc. 4-alkylamino-6-(C3-5 -hydrocarbyl)thieno[2,3-B]thiopyran-2-sulfonamide-7,7-dioxides
US5093332A (en) 1990-10-01 1992-03-03 Merck & Co., Inc. Substituted thieno(2,3-b)(1,4)thiazine-6-sulfonamides as antiglaucoma agents
DK0495421T3 (da) 1991-01-15 1996-12-09 Alcon Lab Inc Anvendelse af carragenaner i topiske ophthalmiske sammensætninger
JP2536806B2 (ja) * 1991-03-27 1996-09-25 アルコン ラボラトリーズ インコーポレイテッド ゲル化多糖類と微粉砕された薬剤担体とを組み合わせた局部眼科用組成物
US5318780A (en) * 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
AU3722793A (en) 1992-09-17 1994-04-12 Alcon Laboratories, Inc. Topical carbonic anhydrase inhibitor composition
SE9301877D0 (sv) * 1993-06-02 1993-06-02 Kabi Pharmacia Ab In situ gel for therapeutic use
CA2337349A1 (en) * 1998-07-21 2000-02-03 Gerald S. Ponticello Ophthalmic compositions for treating ocular hypertension

Also Published As

Publication number Publication date
ZA979219B (en) 1998-07-17
PE106998A1 (es) 1999-01-23
EP0932389B1 (en) 2002-09-04
AU715223B2 (en) 2000-01-20
EP0932389A1 (en) 1999-08-04
ATE223200T1 (de) 2002-09-15
DE69715228D1 (de) 2002-10-10
DE69715228T2 (de) 2003-06-05
FR2754712B1 (fr) 1999-09-03
AU4867397A (en) 1998-05-15
JP2001508035A (ja) 2001-06-19
FR2754712A1 (fr) 1998-04-24
US6264935B1 (en) 2001-07-24
WO1998017249A1 (en) 1998-04-30
HRP970552A2 (en) 1998-08-31
CA2269552A1 (en) 1998-04-30

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