ES2183565T3 - Proceso para aplicar un revestimiento a una unidad farmaceutica. - Google Patents

Proceso para aplicar un revestimiento a una unidad farmaceutica.

Info

Publication number
ES2183565T3
ES2183565T3 ES99926358T ES99926358T ES2183565T3 ES 2183565 T3 ES2183565 T3 ES 2183565T3 ES 99926358 T ES99926358 T ES 99926358T ES 99926358 T ES99926358 T ES 99926358T ES 2183565 T3 ES2183565 T3 ES 2183565T3
Authority
ES
Spain
Prior art keywords
unit
coating
apply
pharmaceutical unit
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99926358T
Other languages
English (en)
Inventor
Livio Maria Cornelli
Grasta Giovanni La
Marco Giuseppe Raffael Marconi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adare Pharmaceuticals SRL
Original Assignee
Eurand International SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand International SpA filed Critical Eurand International SpA
Application granted granted Critical
Publication of ES2183565T3 publication Critical patent/ES2183565T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/003—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic followed by coating of the granules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/12—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in rotating drums

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Glanulating (AREA)

Abstract

Proceso para aplicar un revestimiento a una unidad farmacéutica que comprende: a) la pulverización de la unidad con partículas secas de medicamento y/o excipiente, en la que la unidad y las partículas están a potenciales eléctricas diferentes, de modo que se produzca una atracción electrostática entre ellas; b) la aplicación a la unidad de un aglutinante que comprende un solvente; c) el secado; d) el revestimiento de una película en la unidad con una o más membranas poliméricas con propiedades de liberación controlada, gastrorresistencia, liberación dirigida o enmascaramiento de sabores.
ES99926358T 1998-05-22 1999-05-21 Proceso para aplicar un revestimiento a una unidad farmaceutica. Expired - Lifetime ES2183565T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98109349 1998-05-22

Publications (1)

Publication Number Publication Date
ES2183565T3 true ES2183565T3 (es) 2003-03-16

Family

ID=8231981

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99926358T Expired - Lifetime ES2183565T3 (es) 1998-05-22 1999-05-21 Proceso para aplicar un revestimiento a una unidad farmaceutica.

Country Status (17)

Country Link
US (1) US6569462B1 (es)
EP (1) EP1079814B1 (es)
JP (1) JP2002516166A (es)
KR (1) KR20010034864A (es)
AR (1) AR019145A1 (es)
AT (1) ATE225164T1 (es)
AU (1) AU764525B2 (es)
BR (1) BR9910522A (es)
CA (1) CA2333319A1 (es)
CO (1) CO5070568A1 (es)
DE (1) DE69903282T2 (es)
DK (1) DK1079814T3 (es)
ES (1) ES2183565T3 (es)
NZ (1) NZ509086A (es)
PT (1) PT1079814E (es)
WO (1) WO1999061006A1 (es)
ZA (1) ZA200007208B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2816518B1 (fr) * 2000-11-16 2003-04-25 Bionatec Procede de fabrication de granules
EP1992335A1 (en) 2001-11-01 2008-11-19 Nektar Therapeutics Spray drying methods and compositions thereof
DE10213275C1 (de) * 2002-03-25 2003-12-24 Wagner Ag Altstaetten J Injektor für eine Pulverbeschichtungsanlage
US8709476B2 (en) 2003-11-04 2014-04-29 Supernus Pharmaceuticals, Inc. Compositions of quaternary ammonium compounds containing bioavailability enhancers
DE602004030931D1 (es) * 2003-11-04 2011-02-17 Supernus Pharmaceuticals Inc
FR2861990B1 (fr) 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
DE102005010005A1 (de) * 2005-03-04 2006-12-28 Nunner, Dieter Vorrichtung und Verfahren zur Beschichtung von Kleinteilen
US20110081415A1 (en) * 2005-03-10 2011-04-07 Taisho Pharmaceutical Co., Ltd Coating apparatus
CA2605148C (en) * 2005-04-12 2011-11-22 O'hara Technologies Inc. Continuous feed tablet coating system
DE102005028168B3 (de) * 2005-06-17 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Einrichtung zur Führung eines Gases für Vorrichtungen zum Behandeln körnigen Gutes durch Trocknen, Filmcoaten oder Beschichten, insbesondere Zulufteinheit und Vorrichtung mit einer derartigen Einrichtung
US7862848B2 (en) * 2005-08-03 2011-01-04 The University Of Western Ontario Direct coating solid dosage forms using powdered materials
MX343851B (es) 2006-02-09 2016-11-24 Deka Products Ltd Partnership * Sistemas y métodos de suministro de fluido de bombeo que usan un montaje de aplicación de fuerza.
US11318249B2 (en) 2006-02-09 2022-05-03 Deka Products Limited Partnership Infusion pump assembly
DE202007018978U1 (de) * 2007-06-26 2009-12-31 Volz, Holger Pulverbeschichter
CN101959547B (zh) 2007-12-31 2014-11-26 德卡产品有限公司 输注泵组件
US11357910B2 (en) 2007-12-31 2022-06-14 Deka Products Limited Partnership Pump assembly with switch
WO2010071964A1 (en) * 2008-12-23 2010-07-01 Harmonium International Inc. Turbine coating apparatus and spray gun assembly therefor
US10850298B1 (en) * 2016-05-06 2020-12-01 Madeline A. Kuchinski System for non-contact coating of moving component through a falling flow of coating material
EP3597048B1 (en) * 2018-07-18 2021-04-28 STE Tecpharm, S.L. Coating device with moavable spray heads
CN108926484A (zh) * 2018-07-27 2018-12-04 宁波西敦医药包衣科技有限公司 干粉包衣机
FR3159752B1 (fr) * 2024-02-29 2026-06-12 Ethypharm Sa Système et procédé de poudrage de matière première pulvérulente sur des particules-support en rotation dans une turbine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH624846A5 (en) * 1975-12-15 1981-08-31 Hoffmann La Roche Solid pharmaceutical unit dose form and process and apparatus for producing it
GB8400562D0 (en) * 1984-01-10 1984-02-15 Pharmindey Ltd Electrostatic coating materials
EP0452862B1 (en) * 1990-04-18 1995-07-19 Asahi Kasei Kogyo Kabushiki Kaisha Spherical seed cores, spherical granules and process for production thereof
GB2253164B (en) * 1991-02-22 1994-10-05 Hoechst Uk Ltd Improvements in or relating to electrostatic coating of substrates of medicinal products
US5132142A (en) * 1991-03-19 1992-07-21 Glatt Gmbh Apparatus and method for producing pellets by layering power onto particles
IT1252185B (it) * 1991-12-11 1995-06-05 Therapicon Srl Preparazioni farmaceutiche a liberazione programmata
US5478577A (en) 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
JP3349535B2 (ja) * 1993-01-12 2002-11-25 フロイント産業株式会社 球形顆粒の製造方法
US5411745A (en) * 1994-05-25 1995-05-02 Euro-Celtique, S.A. Powder-layered morphine sulfate formulations
SE9402422D0 (sv) 1994-07-08 1994-07-08 Astra Ab New beads for controlled release and a pharmaceutical preparation containing the same

Also Published As

Publication number Publication date
AU4365299A (en) 1999-12-13
AU764525B2 (en) 2003-08-21
EP1079814A1 (en) 2001-03-07
CA2333319A1 (en) 1999-12-02
NZ509086A (en) 2002-09-27
BR9910522A (pt) 2001-01-16
DE69903282D1 (de) 2002-11-07
DK1079814T3 (da) 2003-02-10
JP2002516166A (ja) 2002-06-04
CO5070568A1 (es) 2001-08-28
ATE225164T1 (de) 2002-10-15
DE69903282T2 (de) 2003-06-26
WO1999061006A1 (en) 1999-12-02
AR019145A1 (es) 2001-12-26
ZA200007208B (en) 2003-01-07
PT1079814E (pt) 2003-02-28
EP1079814B1 (en) 2002-10-02
US6569462B1 (en) 2003-05-27
KR20010034864A (ko) 2001-04-25

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