ES2184260T3 - Sistema de ensayo que utiliza particulas magneticas. - Google Patents

Sistema de ensayo que utiliza particulas magneticas.

Info

Publication number
ES2184260T3
ES2184260T3 ES98921469T ES98921469T ES2184260T3 ES 2184260 T3 ES2184260 T3 ES 2184260T3 ES 98921469 T ES98921469 T ES 98921469T ES 98921469 T ES98921469 T ES 98921469T ES 2184260 T3 ES2184260 T3 ES 2184260T3
Authority
ES
Spain
Prior art keywords
magnetic particles
test system
uses magnetic
analyte
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98921469T
Other languages
English (en)
Inventor
Patricia Connolly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Italia SpA
Original Assignee
Byk Gulden Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Italia SpA filed Critical Byk Gulden Italia SpA
Application granted granted Critical
Publication of ES2184260T3 publication Critical patent/ES2184260T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • G01N33/54333Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/84Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Soft Magnetic Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Hard Magnetic Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Magnetic Treatment Devices (AREA)
  • Paints Or Removers (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)

Abstract

La invención se refiere a un procedimiento para la presencia de un analito o determinación de un parámetro biológico o médico que incluye: añadir un componente de ensayo a un material sensible al pH cargado con partículas magnéticas, en el que el componente del ensayo produce un cambio de pH que es función del analito o del parámetro que se vaya a medir; someter a las partículas magnéticas a un campo magnético oscilante; y medir el efecto del campo magnético sobre las partículas magnéticas.
ES98921469T 1997-04-18 1998-04-20 Sistema de ensayo que utiliza particulas magneticas. Expired - Lifetime ES2184260T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97302671A EP0872736A1 (en) 1997-04-18 1997-04-18 Assay utilizing magnetic particles

Publications (1)

Publication Number Publication Date
ES2184260T3 true ES2184260T3 (es) 2003-04-01

Family

ID=8229303

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98921469T Expired - Lifetime ES2184260T3 (es) 1997-04-18 1998-04-20 Sistema de ensayo que utiliza particulas magneticas.

Country Status (9)

Country Link
US (1) US6235491B1 (es)
EP (2) EP0872736A1 (es)
JP (1) JP3693680B2 (es)
AT (1) ATE224544T1 (es)
DE (1) DE69808071T2 (es)
DK (1) DK0975974T3 (es)
ES (1) ES2184260T3 (es)
PT (1) PT975974E (es)
WO (1) WO1998048282A1 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0872736A1 (en) * 1997-04-18 1998-10-21 Byk Gulden Italia S.p.A. Assay utilizing magnetic particles
US7640083B2 (en) 2002-11-22 2009-12-29 Monroe David A Record and playback system for aircraft
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US8367013B2 (en) * 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
US7314763B2 (en) * 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US7285424B2 (en) * 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7432105B2 (en) 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US20040106190A1 (en) * 2002-12-03 2004-06-03 Kimberly-Clark Worldwide, Inc. Flow-through assay devices
US7247500B2 (en) * 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US20040197819A1 (en) * 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7851209B2 (en) * 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US20050136550A1 (en) * 2003-12-19 2005-06-23 Kimberly-Clark Worldwide, Inc. Flow control of electrochemical-based assay devices
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
GB0413752D0 (en) * 2004-06-19 2004-07-21 Hall Effect Technologies Ltd Method of determining the presence and/or concentration of substances of interest in fluids
US9267167B2 (en) * 2004-06-28 2016-02-23 Becton, Dickinson And Company Dissolvable films and methods including the same
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
WO2006056001A1 (de) * 2004-11-25 2006-06-01 Thomas Schlederer Vorrichtung zur qualitativen und quantitativen bestimmung von analyten
CN106771199B (zh) * 2016-11-18 2018-06-22 湖北师范大学 一种用于非诊断目的的检测肿瘤标志物的比色免疫分析方法
GB2566995B (en) 2017-09-29 2023-01-18 Cotton Mouton Diagnostics Ltd A method of detection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110727A (en) * 1987-04-03 1992-05-05 Cardiovascular Diagnostics, Inc. Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles
EP0685069A4 (en) 1993-02-17 2002-01-23 Cardiovascular Diagnostics Inc IMMUNOASSAY AND AFFINITY TEST BASED ON A DRY-CHEMICAL CASCADE
GB2284890A (en) * 1993-12-17 1995-06-21 Cambridge Life Sciences Analyte sensor based on polymer porosity changes
DE69404653T2 (de) * 1993-05-29 1998-03-19 Cambridge Life Sciences Sensoren beruhend auf polymerumwandlung
ES2220914T3 (es) 1993-08-31 2004-12-16 Roche Diagnostics Corporation Reactivo y metodo para su suso.
EP0872736A1 (en) * 1997-04-18 1998-10-21 Byk Gulden Italia S.p.A. Assay utilizing magnetic particles

Also Published As

Publication number Publication date
JP3693680B2 (ja) 2005-09-07
DK0975974T3 (da) 2003-01-20
ATE224544T1 (de) 2002-10-15
EP0975974B1 (en) 2002-09-18
WO1998048282A1 (en) 1998-10-29
DE69808071D1 (de) 2002-10-24
DE69808071T2 (de) 2003-05-28
EP0872736A1 (en) 1998-10-21
PT975974E (pt) 2003-02-28
EP0975974A1 (en) 2000-02-02
US6235491B1 (en) 2001-05-22
JP2002511926A (ja) 2002-04-16

Similar Documents

Publication Publication Date Title
ES2184260T3 (es) Sistema de ensayo que utiliza particulas magneticas.
EP0659275A4 (en) ANALYTICAL TEST DEVICE INCLUDING NEGATIVE AND POSITIVE CONTROL.
ATE207542T1 (de) Testvorrichtung mit einem stabilen kopplungsfarbstoff zur bestimmung von analyten
AU2805697A (en) Analyte assay using particulate labels
BG104275A (en) Method and device for express analysis of tested parameters in biological samples
GB2365526B (en) Assay apparatus for measuring the amount of an analyte in a biological or environmental sample
TW356519B (en) A device for highest sensitivity magnetic detection of analytes
WO2001050129A3 (en) Compensation for non-specific signals in quantitative immunoassays
ATE386936T1 (de) Selbst-kalibrierendes system für magnetisches bindungs-verfahren
BR9507307A (pt) Novos ésteres de acridinio hidrófilos funcionalizados
DE60013320D1 (de) Analytassay-vorrichtung mit vorabsorbieren-zone
DE68913086D1 (de) Qualitativer Enzymtest zur visuellen Auswertung.
ATE438098T1 (de) Teststreifen enthaltend kontrollmittel und zeitsetzermittel
GR3034868T3 (en) Assay for the determination of protein in a biological sample.
FI813369L (fi) Homogen specifik bindningsprovanordning foerfarande foer dess framstaellning och med anvaendning av anordningen utfoert analytiskt foerfarande
SE9703780D0 (sv) Capillary based immunoassay
ATE555385T1 (de) N1,n12-diacetylspermin als tumormarker
DE69223651D1 (de) Vorrichtungen zur ausführung von ioneneinfangassays
MX9604417A (es) Deteccion de analitos.
SE9803424D0 (sv) Förfarande för kalibrering och mätning i ett mikrodialyssystem samt ett mikrodialyssystem
ES2112898T3 (es) Metodo de ensayo.
DE69710063D1 (de) Probenrörchen zur biologischen analyse organischer flüssigkeiten unter verwendung elektro-optischen geräts
ATE182987T1 (de) Nachweisverfahren und vorrichtung dafür
FR2805545B1 (fr) Procede electrochimique de detection d'acides nucleiques
ES2176229T3 (es) Compuestos quimioluminiscentes de longitud de onda de emision larga y su uso en ensayos de prueba.