ES2184260T3 - Sistema de ensayo que utiliza particulas magneticas. - Google Patents
Sistema de ensayo que utiliza particulas magneticas.Info
- Publication number
- ES2184260T3 ES2184260T3 ES98921469T ES98921469T ES2184260T3 ES 2184260 T3 ES2184260 T3 ES 2184260T3 ES 98921469 T ES98921469 T ES 98921469T ES 98921469 T ES98921469 T ES 98921469T ES 2184260 T3 ES2184260 T3 ES 2184260T3
- Authority
- ES
- Spain
- Prior art keywords
- magnetic particles
- test system
- uses magnetic
- analyte
- assay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000006249 magnetic particle Substances 0.000 title abstract 4
- 238000003556 assay Methods 0.000 abstract 3
- 239000012491 analyte Substances 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
- G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
- G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/84—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving inorganic compounds or pH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Electrochemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Soft Magnetic Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Hard Magnetic Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Magnetic Treatment Devices (AREA)
- Paints Or Removers (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
Abstract
La invención se refiere a un procedimiento para la presencia de un analito o determinación de un parámetro biológico o médico que incluye: añadir un componente de ensayo a un material sensible al pH cargado con partículas magnéticas, en el que el componente del ensayo produce un cambio de pH que es función del analito o del parámetro que se vaya a medir; someter a las partículas magnéticas a un campo magnético oscilante; y medir el efecto del campo magnético sobre las partículas magnéticas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97302671A EP0872736A1 (en) | 1997-04-18 | 1997-04-18 | Assay utilizing magnetic particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2184260T3 true ES2184260T3 (es) | 2003-04-01 |
Family
ID=8229303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98921469T Expired - Lifetime ES2184260T3 (es) | 1997-04-18 | 1998-04-20 | Sistema de ensayo que utiliza particulas magneticas. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6235491B1 (es) |
| EP (2) | EP0872736A1 (es) |
| JP (1) | JP3693680B2 (es) |
| AT (1) | ATE224544T1 (es) |
| DE (1) | DE69808071T2 (es) |
| DK (1) | DK0975974T3 (es) |
| ES (1) | ES2184260T3 (es) |
| PT (1) | PT975974E (es) |
| WO (1) | WO1998048282A1 (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0872736A1 (en) * | 1997-04-18 | 1998-10-21 | Byk Gulden Italia S.p.A. | Assay utilizing magnetic particles |
| US7640083B2 (en) | 2002-11-22 | 2009-12-29 | Monroe David A | Record and playback system for aircraft |
| US20030119203A1 (en) | 2001-12-24 | 2003-06-26 | Kimberly-Clark Worldwide, Inc. | Lateral flow assay devices and methods for conducting assays |
| US8367013B2 (en) * | 2001-12-24 | 2013-02-05 | Kimberly-Clark Worldwide, Inc. | Reading device, method, and system for conducting lateral flow assays |
| US7314763B2 (en) * | 2002-08-27 | 2008-01-01 | Kimberly-Clark Worldwide, Inc. | Fluidics-based assay devices |
| US7285424B2 (en) * | 2002-08-27 | 2007-10-23 | Kimberly-Clark Worldwide, Inc. | Membrane-based assay devices |
| US7432105B2 (en) | 2002-08-27 | 2008-10-07 | Kimberly-Clark Worldwide, Inc. | Self-calibration system for a magnetic binding assay |
| US20040106190A1 (en) * | 2002-12-03 | 2004-06-03 | Kimberly-Clark Worldwide, Inc. | Flow-through assay devices |
| US7247500B2 (en) * | 2002-12-19 | 2007-07-24 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in membrane-based assay devices |
| US20040197819A1 (en) * | 2003-04-03 | 2004-10-07 | Kimberly-Clark Worldwide, Inc. | Assay devices that utilize hollow particles |
| US7851209B2 (en) * | 2003-04-03 | 2010-12-14 | Kimberly-Clark Worldwide, Inc. | Reduction of the hook effect in assay devices |
| US20050112703A1 (en) | 2003-11-21 | 2005-05-26 | Kimberly-Clark Worldwide, Inc. | Membrane-based lateral flow assay devices that utilize phosphorescent detection |
| US7943395B2 (en) | 2003-11-21 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Extension of the dynamic detection range of assay devices |
| US7713748B2 (en) | 2003-11-21 | 2010-05-11 | Kimberly-Clark Worldwide, Inc. | Method of reducing the sensitivity of assay devices |
| US20050136550A1 (en) * | 2003-12-19 | 2005-06-23 | Kimberly-Clark Worldwide, Inc. | Flow control of electrochemical-based assay devices |
| US7943089B2 (en) | 2003-12-19 | 2011-05-17 | Kimberly-Clark Worldwide, Inc. | Laminated assay devices |
| GB0413752D0 (en) * | 2004-06-19 | 2004-07-21 | Hall Effect Technologies Ltd | Method of determining the presence and/or concentration of substances of interest in fluids |
| US9267167B2 (en) * | 2004-06-28 | 2016-02-23 | Becton, Dickinson And Company | Dissolvable films and methods including the same |
| US7521226B2 (en) | 2004-06-30 | 2009-04-21 | Kimberly-Clark Worldwide, Inc. | One-step enzymatic and amine detection technique |
| WO2006056001A1 (de) * | 2004-11-25 | 2006-06-01 | Thomas Schlederer | Vorrichtung zur qualitativen und quantitativen bestimmung von analyten |
| CN106771199B (zh) * | 2016-11-18 | 2018-06-22 | 湖北师范大学 | 一种用于非诊断目的的检测肿瘤标志物的比色免疫分析方法 |
| GB2566995B (en) | 2017-09-29 | 2023-01-18 | Cotton Mouton Diagnostics Ltd | A method of detection |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5110727A (en) * | 1987-04-03 | 1992-05-05 | Cardiovascular Diagnostics, Inc. | Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles |
| EP0685069A4 (en) | 1993-02-17 | 2002-01-23 | Cardiovascular Diagnostics Inc | IMMUNOASSAY AND AFFINITY TEST BASED ON A DRY-CHEMICAL CASCADE |
| GB2284890A (en) * | 1993-12-17 | 1995-06-21 | Cambridge Life Sciences | Analyte sensor based on polymer porosity changes |
| DE69404653T2 (de) * | 1993-05-29 | 1998-03-19 | Cambridge Life Sciences | Sensoren beruhend auf polymerumwandlung |
| ES2220914T3 (es) | 1993-08-31 | 2004-12-16 | Roche Diagnostics Corporation | Reactivo y metodo para su suso. |
| EP0872736A1 (en) * | 1997-04-18 | 1998-10-21 | Byk Gulden Italia S.p.A. | Assay utilizing magnetic particles |
-
1997
- 1997-04-18 EP EP97302671A patent/EP0872736A1/en not_active Withdrawn
-
1998
- 1998-04-20 DK DK98921469T patent/DK0975974T3/da active
- 1998-04-20 ES ES98921469T patent/ES2184260T3/es not_active Expired - Lifetime
- 1998-04-20 DE DE69808071T patent/DE69808071T2/de not_active Expired - Lifetime
- 1998-04-20 EP EP98921469A patent/EP0975974B1/en not_active Expired - Lifetime
- 1998-04-20 US US09/403,012 patent/US6235491B1/en not_active Expired - Fee Related
- 1998-04-20 PT PT98921469T patent/PT975974E/pt unknown
- 1998-04-20 WO PCT/EP1998/002308 patent/WO1998048282A1/en not_active Ceased
- 1998-04-20 AT AT98921469T patent/ATE224544T1/de not_active IP Right Cessation
- 1998-04-20 JP JP54500798A patent/JP3693680B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP3693680B2 (ja) | 2005-09-07 |
| DK0975974T3 (da) | 2003-01-20 |
| ATE224544T1 (de) | 2002-10-15 |
| EP0975974B1 (en) | 2002-09-18 |
| WO1998048282A1 (en) | 1998-10-29 |
| DE69808071D1 (de) | 2002-10-24 |
| DE69808071T2 (de) | 2003-05-28 |
| EP0872736A1 (en) | 1998-10-21 |
| PT975974E (pt) | 2003-02-28 |
| EP0975974A1 (en) | 2000-02-02 |
| US6235491B1 (en) | 2001-05-22 |
| JP2002511926A (ja) | 2002-04-16 |
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