ES2188139T3 - Procedimiento para la preparacion de un biomaterial esencialmente constituido por un hidroxiapatito fosfocalcico. - Google Patents

Procedimiento para la preparacion de un biomaterial esencialmente constituido por un hidroxiapatito fosfocalcico.

Info

Publication number
ES2188139T3
ES2188139T3 ES99909015T ES99909015T ES2188139T3 ES 2188139 T3 ES2188139 T3 ES 2188139T3 ES 99909015 T ES99909015 T ES 99909015T ES 99909015 T ES99909015 T ES 99909015T ES 2188139 T3 ES2188139 T3 ES 2188139T3
Authority
ES
Spain
Prior art keywords
phosphocalcico
hydroxiapatite
biomaterial
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99909015T
Other languages
English (en)
Inventor
J Lacout
Zineb Hatim
Michele Frache-Botton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teknimed SAS
Original Assignee
Teknimed SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teknimed SAS filed Critical Teknimed SAS
Application granted granted Critical
Publication of ES2188139T3 publication Critical patent/ES2188139T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
    • C04B28/34—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders
    • C04B28/346—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders the phosphate binder being present in the starting composition as a mixture of free acid and one or more phosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
    • A61K6/838—Phosphorus compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
    • A61K6/864—Phosphate cements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B25/00—Phosphorus; Compounds thereof
    • C01B25/16—Oxyacids of phosphorus; Salts thereof
    • C01B25/26—Phosphates
    • C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
    • C04B28/34—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
    • C04B2111/00474—Uses not provided for elsewhere in C04B2111/00
    • C04B2111/00836—Uses not provided for elsewhere in C04B2111/00 for medical or dental applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Ceramic Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Structural Engineering (AREA)
  • Materials Engineering (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)

Abstract

La invención ser refiere a un procedimiento para preparar un biomaterial en el que la fase de endurecimiento se lleva a cabo en la zona de utilización, el procedimiento comprende los siguientes pasos: a) preparar previamente un producto sólido en polvo a partir de fosfato tricálcico y de fosfato tetracálcico con una proporción Ca/P que oscila básicamente entre 1.40 y 1.90; b) preparar una solución acuosa que contenga iones de calcio e iones de fosfato con una proporción Ca/P superior a 0,20 e inferior a 0,50; y c) mezclar la solución acuosa y el producto en polvo añadiendo, sí se necesitase, agua, de manera que la proporción de líquido/sólido de la mezcla oscile entre 0,30 y 0,65 y la proporción de Ca/P de la pasta resultante oscile entre 1,50 y 1,67, la pasta se dispone en la zona de utilización y se endurece in situ.
ES99909015T 1998-03-20 1999-03-17 Procedimiento para la preparacion de un biomaterial esencialmente constituido por un hidroxiapatito fosfocalcico. Expired - Lifetime ES2188139T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9803459A FR2776282B1 (fr) 1998-03-20 1998-03-20 Procede de preparation d'un biomateriau a base d'hydroxyapatite, biomateriau obtenu et application chirurgicale ou dentaire

Publications (1)

Publication Number Publication Date
ES2188139T3 true ES2188139T3 (es) 2003-06-16

Family

ID=9524294

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99909015T Expired - Lifetime ES2188139T3 (es) 1998-03-20 1999-03-17 Procedimiento para la preparacion de un biomaterial esencialmente constituido por un hidroxiapatito fosfocalcico.

Country Status (8)

Country Link
US (2) US6521264B1 (es)
EP (1) EP0984902B1 (es)
AT (1) ATE228481T1 (es)
AU (1) AU2841099A (es)
DE (1) DE69904127D1 (es)
ES (1) ES2188139T3 (es)
FR (1) FR2776282B1 (es)
WO (1) WO1999048809A1 (es)

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FR2805748B1 (fr) 2000-03-01 2002-09-13 Ceravic Procede de preparation d'un materiau pateux phosphocalcique injectable en vue de former un biomateriau apatitique et application chirurgicale ou dentaire
DE10032220A1 (de) * 2000-07-03 2002-01-24 Sanatis Gmbh Magnesium-ammonium-phosphat-Zemente, deren Herstellung und Verwendung
US6649669B2 (en) * 2001-12-28 2003-11-18 American Dental Association Health Foundation Single solution bonding formulation
US20040127563A1 (en) * 2002-03-22 2004-07-01 Deslauriers Richard J. Methods of performing medical procedures which promote bone growth, compositions which promote bone growth, and methods of making such compositions
AUPS244002A0 (en) 2002-05-20 2002-06-13 John Kohnke Products Pty Ltd Agent delivery system
AU2003229357B2 (en) * 2002-05-20 2008-05-15 John Kohnke Agent delivery system
US7273523B2 (en) 2002-06-07 2007-09-25 Kyphon Inc. Strontium-apatite-cement-preparations, cements formed therefrom, and uses thereof
CN1290483C (zh) * 2002-06-20 2006-12-20 多克萨股份公司 用于牙齿填充材料或植入材料的体系、粉末材料、水合液体、植入材料和实现结合的方法
ES2222778B2 (es) * 2002-07-04 2005-10-01 Universidade De Santiago De Compostela PROCEDIMIENTO PARA INCREMENTAR LAS PROPIEDADES MECANICAS DE BIOCERAMICAS DE FOSFATOS CALCICOS MEDIANTE LA ADICION DE GELES CON RELACION Ca/P CONTROLADA A LOS POLVOS DE MATERIAS PRIMAS.
US7842300B2 (en) * 2002-07-31 2010-11-30 Dentsply International, Inc. Bone repair putty
US8876532B2 (en) 2002-07-31 2014-11-04 Dentsply International Inc. Bone repair putty
DE602004031847D1 (de) * 2003-08-08 2011-04-28 Argonne Nat Lab Argonne Verfahren und produkt für eine phosphosilikataufschlämmung zur verwendung in der zahnmedizin und knochenzemente in verbindung damit
US7981461B2 (en) * 2004-01-30 2011-07-19 Georgette Frederick S Metallic bone implant having improved implantability and method of making the same
EP1789088A4 (en) * 2004-03-24 2009-12-30 Doctor S Res Group Inc METHOD FOR IMPLEMENTING MEDICAL METHODS FOR PROMOTING BONE GROWTH, METHOD FOR PRODUCING COMPOUNDS FOR PROMOTING BONE GROWTH AND DEVICE FOR USE IN SUCH PROCEDURES
DE102004063912B4 (de) * 2004-04-22 2007-09-20 Siltronic Ag Verfahren zum versandfertigen Verpacken von Halbleiterscheiben
ES2396133T3 (es) 2004-04-27 2013-02-19 Kyphon SÀRl Composiciones de sustitución osea y método de uso
CA2587278A1 (en) * 2004-11-16 2006-05-26 3M Innovative Properties Company Dental fillers, methods, compositions including a caseinate
CN101098673B (zh) 2004-11-16 2012-02-29 3M创新有限公司 包括磷酸盐的牙科填料和组合物
AU2005306857A1 (en) 2004-11-16 2006-05-26 3M Innovative Properties Company Dental compositions with calcium phosphorus releasing glass
AU2005306869B2 (en) 2004-11-16 2011-11-10 3M Innovative Properties Company Dental fillers including a phosphorus­containing surface treatment
US7651701B2 (en) * 2005-08-29 2010-01-26 Sanatis Gmbh Bone cement composition and method of making the same
US8287914B2 (en) * 2006-01-12 2012-10-16 Rutgers, The State University Of New Jersey Biomimetic hydroxyapatite synthesis
US20100040668A1 (en) * 2006-01-12 2010-02-18 Rutgers, The State University Of New Jersey Biomimetic Hydroxyapatite Composite Materials and Methods for the Preparation Thereof
US8361129B2 (en) * 2006-04-28 2013-01-29 Depuy Spine, Inc. Large diameter bone anchor assembly
US7754005B2 (en) * 2006-05-02 2010-07-13 Kyphon Sarl Bone cement compositions comprising an indicator agent and related methods thereof
US7507286B2 (en) * 2006-06-08 2009-03-24 Sanatis Gmbh Self-foaming cement for void filling and/or delivery systems
AU2007300585A1 (en) * 2006-09-21 2008-04-03 Kyphon Sarl Diammonium phosphate and other ammonium salts and their use in preventing clotting
US20080195223A1 (en) * 2006-11-03 2008-08-14 Avram Allan Eddin Materials and Methods and Systems for Delivering Localized Medical Treatments
US9480485B2 (en) 2006-12-15 2016-11-01 Globus Medical, Inc. Devices and methods for vertebrostenting
WO2008076330A1 (en) 2006-12-15 2008-06-26 Soteira, Inc. Drills and methods for vertebrostenting
EP2229130A2 (en) * 2007-12-13 2010-09-22 3M Innovative Properties Company Remineralizing compositions and methods
US7968616B2 (en) * 2008-04-22 2011-06-28 Kyphon Sarl Bone cement composition and method
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Also Published As

Publication number Publication date
DE69904127D1 (de) 2003-01-09
US20030108589A1 (en) 2003-06-12
ATE228481T1 (de) 2002-12-15
FR2776282B1 (fr) 2000-05-19
EP0984902A1 (fr) 2000-03-15
AU2841099A (en) 1999-10-18
WO1999048809A1 (fr) 1999-09-30
US6521264B1 (en) 2003-02-18
FR2776282A1 (fr) 1999-09-24
EP0984902B1 (fr) 2002-11-27

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