ES2188189T3 - Composiciones que comprenden derivados de acido fenil-amino-tiofeno-acetico para el tratamiento del sindrome de angustia respiratoria aguda o de adultos (ards) y del sindrome de angustia respiratoria de niños (irds). - Google Patents
Composiciones que comprenden derivados de acido fenil-amino-tiofeno-acetico para el tratamiento del sindrome de angustia respiratoria aguda o de adultos (ards) y del sindrome de angustia respiratoria de niños (irds).Info
- Publication number
- ES2188189T3 ES2188189T3 ES99931116T ES99931116T ES2188189T3 ES 2188189 T3 ES2188189 T3 ES 2188189T3 ES 99931116 T ES99931116 T ES 99931116T ES 99931116 T ES99931116 T ES 99931116T ES 2188189 T3 ES2188189 T3 ES 2188189T3
- Authority
- ES
- Spain
- Prior art keywords
- angustia
- respiratory
- irds
- ards
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000000241 respiratory effect Effects 0.000 title 2
- DAXFBZYFEMRYIF-UHFFFAOYSA-N C1(=CC=CC=C1)C=1C(=C(SC1)CC(=O)O)N Chemical class C1(=CC=CC=C1)C=1C(=C(SC1)CC(=O)O)N DAXFBZYFEMRYIF-UHFFFAOYSA-N 0.000 title 1
- 230000001154 acute effect Effects 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 2-(2-hydroxyethoxy)ethyl Chemical group 0.000 abstract 1
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 abstract 1
- 201000000028 adult respiratory distress syndrome Diseases 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000003580 lung surfactant Chemical class 0.000 abstract 1
- 229940066294 lung surfactant Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
Una composición para el tratamiento del síndrome de Angustia Respiratoria de Niños (IRDS) y del síndrome de Angustia Respiratoria de Adultos (ARDS), que comprende un compuesto de la Fórmula**(Fórmula)** en el que R1 es hidrógeno o 2-(2-hidroxi-etoxi)etilo y/o una sal farmacológicamente tolerable de este compuesto, y un agente tensioactivo pulmonar.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19827907A DE19827907C2 (de) | 1998-06-23 | 1998-06-23 | Neue pharmazeutische Zusammensetzungen zur Behandlung von IRDS und ARDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2188189T3 true ES2188189T3 (es) | 2003-06-16 |
Family
ID=7871729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99931116T Expired - Lifetime ES2188189T3 (es) | 1998-06-23 | 1999-06-19 | Composiciones que comprenden derivados de acido fenil-amino-tiofeno-acetico para el tratamiento del sindrome de angustia respiratoria aguda o de adultos (ards) y del sindrome de angustia respiratoria de niños (irds). |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1098645B1 (es) |
| JP (1) | JP4503835B2 (es) |
| AT (1) | ATE227989T1 (es) |
| AU (1) | AU4774699A (es) |
| CA (1) | CA2335353C (es) |
| DE (2) | DE19827907C2 (es) |
| DK (1) | DK1098645T3 (es) |
| ES (1) | ES2188189T3 (es) |
| PT (1) | PT1098645E (es) |
| WO (1) | WO1999066926A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1276495B1 (en) * | 2000-04-12 | 2006-04-19 | ALTANA Pharma AG | Use of recombinant pulmonary surfactant for the early treatment of acute pulmonary diseases |
| GB0026239D0 (en) * | 2000-10-26 | 2000-12-13 | Britannia Pharmaceuticals Ltd | Surface active lipids in treatment of wet lung |
| US7238664B2 (en) | 2003-06-16 | 2007-07-03 | Altana Pharma Ag | Composition comprising a pulmonary surfactant and a PDE5 inhibitor for the treatment of lung diseases |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| YU118379A (en) * | 1978-05-24 | 1983-02-28 | Byk Gulden Lomberg Chemischefa | Process for preparing phenylaminothiophene acetic acid |
| US4459362A (en) * | 1982-02-02 | 1984-07-10 | Hana Biologics, Inc. | Immunoassay of phospholipid, such as phosphatidyl choline, in fluids such as amniotic |
-
1998
- 1998-06-23 DE DE19827907A patent/DE19827907C2/de not_active Expired - Fee Related
-
1999
- 1999-06-19 DE DE69904051T patent/DE69904051T2/de not_active Expired - Lifetime
- 1999-06-19 AT AT99931116T patent/ATE227989T1/de active
- 1999-06-19 PT PT99931116T patent/PT1098645E/pt unknown
- 1999-06-19 WO PCT/EP1999/004276 patent/WO1999066926A1/en not_active Ceased
- 1999-06-19 ES ES99931116T patent/ES2188189T3/es not_active Expired - Lifetime
- 1999-06-19 JP JP2000555612A patent/JP4503835B2/ja not_active Expired - Fee Related
- 1999-06-19 CA CA002335353A patent/CA2335353C/en not_active Expired - Fee Related
- 1999-06-19 AU AU47746/99A patent/AU4774699A/en not_active Abandoned
- 1999-06-19 EP EP99931116A patent/EP1098645B1/en not_active Expired - Lifetime
- 1999-06-19 DK DK99931116T patent/DK1098645T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2335353A1 (en) | 1999-12-29 |
| DK1098645T3 (da) | 2003-03-10 |
| AU4774699A (en) | 2000-01-10 |
| JP4503835B2 (ja) | 2010-07-14 |
| ATE227989T1 (de) | 2002-12-15 |
| CA2335353C (en) | 2009-05-12 |
| WO1999066926A1 (en) | 1999-12-29 |
| PT1098645E (pt) | 2003-04-30 |
| DE69904051T2 (de) | 2004-08-19 |
| DE19827907A1 (de) | 1999-12-30 |
| EP1098645B1 (en) | 2002-11-20 |
| DE19827907C2 (de) | 2003-05-15 |
| DE69904051D1 (de) | 2003-01-02 |
| EP1098645A1 (en) | 2001-05-16 |
| JP2002518445A (ja) | 2002-06-25 |
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