ES2188214T5 - Composicion antioxidante que comprende acetil l-carnitina y acido alfa-lipoico. - Google Patents
Composicion antioxidante que comprende acetil l-carnitina y acido alfa-lipoico. Download PDFInfo
- Publication number
- ES2188214T5 ES2188214T5 ES99939612T ES99939612T ES2188214T5 ES 2188214 T5 ES2188214 T5 ES 2188214T5 ES 99939612 T ES99939612 T ES 99939612T ES 99939612 T ES99939612 T ES 99939612T ES 2188214 T5 ES2188214 T5 ES 2188214T5
- Authority
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- Prior art keywords
- carnitine
- acid
- composition
- acetyl
- lipoic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM98A0566 | 1998-09-01 | ||
| IT1998RM000566A IT1302307B1 (it) | 1998-09-01 | 1998-09-01 | Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2188214T3 ES2188214T3 (es) | 2003-06-16 |
| ES2188214T5 true ES2188214T5 (es) | 2010-06-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES99939612T Expired - Lifetime ES2188214T5 (es) | 1998-09-01 | 1999-08-19 | Composicion antioxidante que comprende acetil l-carnitina y acido alfa-lipoico. |
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| US (1) | US6365622B1 (fr) |
| EP (1) | EP1112005B2 (fr) |
| JP (1) | JP4361215B2 (fr) |
| KR (1) | KR20010079699A (fr) |
| CN (1) | CN1315835A (fr) |
| AR (1) | AR022076A1 (fr) |
| AT (1) | ATE228312T1 (fr) |
| AU (1) | AU773424B2 (fr) |
| BR (1) | BR9913288A (fr) |
| CA (1) | CA2341973C (fr) |
| CZ (1) | CZ2001541A3 (fr) |
| DE (1) | DE69904208T3 (fr) |
| DK (1) | DK1112005T4 (fr) |
| EE (1) | EE200100113A (fr) |
| ES (1) | ES2188214T5 (fr) |
| HK (1) | HK1039730A1 (fr) |
| HU (1) | HU229165B1 (fr) |
| IL (1) | IL141435A0 (fr) |
| IS (1) | IS5850A (fr) |
| IT (1) | IT1302307B1 (fr) |
| MA (1) | MA25284A1 (fr) |
| NO (1) | NO20010954L (fr) |
| PL (1) | PL212737B1 (fr) |
| PT (1) | PT1112005E (fr) |
| SK (1) | SK2632001A3 (fr) |
| TN (1) | TNSN99163A1 (fr) |
| TR (1) | TR200100610T2 (fr) |
| WO (1) | WO2000011968A1 (fr) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7828200A (en) | 1999-09-23 | 2001-04-24 | Juvenon Corporation | Nutritional supplement for increased energy and stamina |
| US6562869B1 (en) | 1999-09-23 | 2003-05-13 | Juvenon, Inc. | Nutritional supplement for increased energy and stamina |
| EP1248609A4 (fr) * | 1999-11-03 | 2007-08-01 | Juvenon Inc | Traitement de la perte de memoire benigne |
| US6664287B2 (en) * | 2000-03-15 | 2003-12-16 | Bethesda Pharmaceuticals, Inc. | Antioxidants |
| DE10036797A1 (de) * | 2000-07-28 | 2002-02-07 | Beiersdorf Ag | Verwendung von Kombinationen mit einem Gehalt an Carnitinen |
| CN1477958A (zh) * | 2000-10-31 | 2004-02-25 | 高露洁-棕榄公司 | 组合物及方法 |
| US20020076470A1 (en) * | 2000-10-31 | 2002-06-20 | Colgate-Palmolive Company | Composition and method |
| US8669282B2 (en) | 2000-10-31 | 2014-03-11 | Hill's Pet Nutrition, Inc. | Companion animal compositions including lipoic acid and methods of use thereof |
| JP2010142237A (ja) * | 2000-10-31 | 2010-07-01 | Colgate Palmolive Co | 組成物及び方法 |
| US6555573B2 (en) | 2000-12-21 | 2003-04-29 | The Quigley Corporation | Method and composition for the topical treatment of diabetic neuropathy |
| JP2004519241A (ja) * | 2001-03-09 | 2004-07-02 | ソシエテ デ プロデユイ ネツスル ソシエテ アノニム | 高齢化に伴う生理的障害を改善し寿命を延ばす組成物 |
| SE0102380D0 (sv) * | 2001-07-02 | 2001-07-02 | Macronova Ab | Kräm för behandling av åldersförändringar i huden hos människa |
| US6923960B2 (en) * | 2001-10-03 | 2005-08-02 | Vsl Pharmaceuticals Inc. | Antioxidant combination composition and use thereof |
| WO2003053336A2 (fr) * | 2001-12-19 | 2003-07-03 | The Quigley Corporation | Procedes de traitement de malaises neurovasculaires peripheriques |
| US20060127505A1 (en) * | 2002-01-16 | 2006-06-15 | David Haines | Anti-inflammatory formulations |
| WO2003072052A2 (fr) * | 2002-02-22 | 2003-09-04 | Albany College Of Pharmacy | Methodes et composes utiles dans l'inhibition par agression radicalaire et/ou oxydante et dans le traitement et la prevention de maladie |
| JP2006506361A (ja) * | 2002-10-11 | 2006-02-23 | クレアグリ， インコーポレイテッド | カルニチンおよび酸化防止ポリフェノールの治療用組合せ |
| US7083813B2 (en) | 2002-11-06 | 2006-08-01 | The Quigley Corporation | Methods for the treatment of peripheral neural and vascular ailments |
| ITRM20020620A1 (it) * | 2002-12-13 | 2004-06-14 | Sigma Tau Ind Farmaceuti | Uso delle carnitine per la prevenzione e/o il trattamento dei disturbi causati dall'andropausa. |
| DE10258239A1 (de) * | 2002-12-13 | 2004-06-24 | Degussa Ag | Formulierung enthaltend alpha-Liponsäure(-Derivate) als alleinigen Wirkstoff bei nichtchronischen alkoholinduzierten Intoxikationen |
| US20040265345A1 (en) * | 2003-06-30 | 2004-12-30 | Perricone Nicholas V. | Treatment of skin damage using acetyl carnitine and lipoic acid |
| US7999003B2 (en) * | 2003-08-26 | 2011-08-16 | Mannatech, Incorporated | Antioxidant compositions and methods thereto |
| US20050214413A1 (en) * | 2003-08-26 | 2005-09-29 | Mannatech, Inc. | Methods and compositions for modified release of nutritional supplements |
| WO2005067972A1 (fr) * | 2003-12-31 | 2005-07-28 | Integrative Health Consulting, Inc. | Compositions nutritives et methodes permettant d'ameliorer l'efficacite du systeme immunitaire |
| US20050232911A1 (en) * | 2004-04-19 | 2005-10-20 | Schreiber Brian D | Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid |
| US8569367B2 (en) * | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| EP1817022B1 (fr) * | 2004-11-24 | 2018-04-25 | Hill's Pet Nutrition, Inc. | Procedes destines a accroitre la reponse immunitaire chez un animal |
| US20090176864A1 (en) * | 2004-11-24 | 2009-07-09 | Hill's Pet Nutrition, Inc. | Methods For Improving Hepatic and Immune Function In An Animal |
| DK1817058T3 (en) * | 2004-11-24 | 2015-12-07 | Hills Pet Nutrition Inc | COMPOSITION FOR USE FOR IMPROVING THE hepatic clearance xenobiotics WITH AN ANIMAL |
| CA2592389C (fr) | 2004-12-29 | 2013-05-14 | Hill's Pet Nutrition, Inc. | Methodes permettant d'inhiber un declin des facultes d'apprentissage et/ou de la memoire chez les animaux |
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| US8252742B2 (en) | 2004-12-30 | 2012-08-28 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| JP5685362B2 (ja) * | 2005-04-26 | 2015-03-18 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニＳｉｇｍａ−Ｔａｕ Ｉｎｄｕｓｔｒｉｅ Ｆａｒｍａｃｅｕｔｉｃｈｅ Ｒｉｕｎｉｔｅ Ｓｏｃｉｅｔａ Ｐｅｒ Ａｚｉｏｎｉ | 有痛性末梢糖尿病性神経障害の予防のためのアセチルｌ−カルニチン |
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| US8318954B2 (en) * | 2006-02-23 | 2012-11-27 | Nou Life Sciences, Inc. | Cleavable carnitine compound |
| CN101045048B (zh) * | 2006-03-27 | 2011-05-18 | 中国科学院上海生命科学研究院 | 线粒体营养素组合物的应用 |
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| KR100811110B1 (ko) * | 2007-02-21 | 2008-03-06 | 주식회사 디피아이 솔루션스 | 수분산성 α-리포산 캡슐 조성물을 함유하는 어류의 면역력증강용 사료첨가제 및 그 사용방법. |
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| US20090054513A1 (en) * | 2007-08-22 | 2009-02-26 | Response Scientific, Inc. | Method of managing blood glucose levels, insulin levels and/or insulin receptor functionality in individuals with diabetes, polycystic ovarian syndrome and/or alzheimer's disease |
| KR100903549B1 (ko) * | 2008-07-29 | 2009-06-23 | 주식회사 카이로제닉스 | 균질한 결정성의 아세틸-ｌ-카르니틴과 티옥트산 칼륨염의 복합염, 이의 제조방법 및 이를 포함하는 약학적 조성물 |
| JP2012508267A (ja) * | 2008-11-11 | 2012-04-05 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | セルライトの処置に有用な化合物 |
| EP2389931A1 (fr) * | 2010-05-21 | 2011-11-30 | Raw Materials Internatinal LLC | Compositions pharmaceutiques aqueuses comprenant de l'acide lipoïque en tant qu'antioxydant |
| US9040082B2 (en) | 2011-06-24 | 2015-05-26 | K-Pax Pharmaceuticals, Inc. | Compositions and methods for treatment of chronic fatigue |
| US8957048B2 (en) | 2011-10-06 | 2015-02-17 | Allergan, Inc. | Compositions for the treatment of dry eye |
| US9907826B2 (en) | 2011-12-07 | 2018-03-06 | Allergan, Inc. | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
| PT2787969T (pt) | 2011-12-07 | 2021-11-09 | Allergan Inc | Entrega eficiente de lípidos para o filme lacrimal humano utilizando um sistema de emulsão sensível ao sal |
| US20140371280A1 (en) * | 2013-03-15 | 2014-12-18 | Shinichi Okuyama | Method of treating diabetic peripheral neuropathy through amendment of pre-neuronal diabetic coagulative micro-angiopathy and neuronal deficiency of mitochondrial ATP production, and through induction of neuronal regeneration |
| US20190290609A1 (en) * | 2014-03-19 | 2019-09-26 | Epitech Group S.P.A. | Pharmaceutical composition comprising palmitoylethanolamide and l-acetylcarnitine |
| CA2965671A1 (fr) | 2014-10-24 | 2016-04-28 | Robert Shorr | Procedes et compositions permettant le traitement de pre-diabete, de diabete et de syndrome metabolique |
| CA2967413C (fr) | 2014-11-25 | 2023-08-15 | Allergan, Inc. | Compositions ophtalmiques contenant des huiles d'omega-3 stabilisees pardes antioxydants |
| EP3277273B1 (fr) | 2015-03-31 | 2020-02-26 | Kolinpharma S.p.A. | Composition utilisable en vue du traitement de neuropathies et/ou de la douleur neuropathique |
| ES2815552T3 (es) | 2015-08-24 | 2021-03-30 | Vitrolife Sweden Ab | Medio de cultivo |
| EP3849542A1 (fr) * | 2018-09-10 | 2021-07-21 | URIACH ITALY S.r.l. | Composition comprenant de l'acide lipoïque et de la vitamine d pour la prévention et le traitement de maladies neurodégénératives et de neuropathies périphériques |
| CN111467385B (zh) * | 2019-01-24 | 2022-05-17 | 深圳市华大农业应用研究院 | 组合物在预防或治疗神经退行性疾病中的用途 |
| EP3773012B1 (fr) * | 2019-04-18 | 2021-06-30 | Simo Rasi | Composition destinée à être utilisée dans la prévention ou la réduction du stress oxydatif et de maladies neurodégénératives |
| US12208077B2 (en) | 2021-04-06 | 2025-01-28 | Celagenex Research (India) Pvt. Ltd. | Synergistic composition for potentiating stabilized ATP |
| CN112999220B (zh) * | 2021-04-07 | 2022-12-13 | 中国人民解放军南部战区总医院 | α-硫辛酸在作为和/或制备金属β-内酰胺酶抑制剂中的应用 |
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| US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
| WO1997002041A1 (fr) | 1995-07-03 | 1997-01-23 | Crandall Wilson T | Traitement transcutane et oral de l'alopecie androgene |
| IT1283967B1 (it) * | 1996-03-29 | 1998-05-07 | Sigma Tau Ind Farmaceuti | Uso di l-carnitina o derivati della l-carnitina ed antiossidanti nella prevenzione e trattamento di patologie derivanti da danni ossidativi |
| US5977162A (en) | 1996-09-16 | 1999-11-02 | Seidman; Michael D. | Therapeutic treatment for auditory function |
| EP1021177A4 (fr) * | 1997-02-04 | 2002-05-15 | John V Kosbab | Compositions et procedes destines a la prevention et au traitement de maladies degeneratives vasculaires |
| IT1291113B1 (it) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizione nutritiva terapeutica per soggetti affetti da diabete mellito |
| US5916912A (en) * | 1997-06-16 | 1999-06-29 | The Regents Of The University Of California | Dietary composition for enhancing metabolism and alleviating oxidative stress |
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1998
- 1998-09-01 IT IT1998RM000566A patent/IT1302307B1/it active IP Right Grant
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1999
- 1999-08-06 MA MA25719A patent/MA25284A1/fr unknown
- 1999-08-19 CN CN99810437A patent/CN1315835A/zh active Pending
- 1999-08-19 AT AT99939612T patent/ATE228312T1/de active
- 1999-08-19 EP EP99939612A patent/EP1112005B2/fr not_active Expired - Lifetime
- 1999-08-19 WO PCT/IT1999/000268 patent/WO2000011968A1/fr not_active Ceased
- 1999-08-19 EE EEP200100113A patent/EE200100113A/xx unknown
- 1999-08-19 PL PL346318A patent/PL212737B1/pl unknown
- 1999-08-19 CZ CZ2001541A patent/CZ2001541A3/cs unknown
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- 1999-08-19 IL IL14143599A patent/IL141435A0/xx unknown
- 1999-08-19 BR BR9913288-5A patent/BR9913288A/pt not_active Application Discontinuation
- 1999-08-19 US US09/786,153 patent/US6365622B1/en not_active Expired - Lifetime
- 1999-08-19 HK HK02101323.4A patent/HK1039730A1/zh unknown
- 1999-08-19 CA CA002341973A patent/CA2341973C/fr not_active Expired - Lifetime
- 1999-08-19 SK SK263-2001A patent/SK2632001A3/sk unknown
- 1999-08-19 KR KR1020017002527A patent/KR20010079699A/ko not_active Withdrawn
- 1999-08-19 DK DK99939612.0T patent/DK1112005T4/da active
- 1999-08-19 AU AU53871/99A patent/AU773424B2/en not_active Expired
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- 1999-08-19 DE DE69904208T patent/DE69904208T3/de not_active Expired - Lifetime
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- 1999-08-30 TN TNTNSN99163A patent/TNSN99163A1/fr unknown
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2001
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