ES2188787T3 - Compuesto medicamentoso de micela copolimera y metodo para su preparacion. - Google Patents

Compuesto medicamentoso de micela copolimera y metodo para su preparacion.

Info

Publication number
ES2188787T3
ES2188787T3 ES96932066T ES96932066T ES2188787T3 ES 2188787 T3 ES2188787 T3 ES 2188787T3 ES 96932066 T ES96932066 T ES 96932066T ES 96932066 T ES96932066 T ES 96932066T ES 2188787 T3 ES2188787 T3 ES 2188787T3
Authority
ES
Spain
Prior art keywords
micela
hydrophobe
copolimera
preparation
medicinal compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96932066T
Other languages
English (en)
Inventor
Sung Chul Kim
Eun Ok Chang
In Suk Song
Chaul Min Pai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Samyang Corp
Original Assignee
Samyang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samyang Corp filed Critical Samyang Corp
Application granted granted Critical
Publication of ES2188787T3 publication Critical patent/ES2188787T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA PRESENTE INVENCION TRATA DE UN SISTEMA DE ADMINISTRACION DE FARMACOS EN MICELAS, QUE INCLUYE UN COPOLIMERO EN BLOQUE QUE PRESENTA BLOQUES HIDROFOBOS E HIDROFILOS; SIENDO EL BLOQUE HIDROFOBO UN POLIMERO HIDROFOBO BIODEGRADABLE SELECCIONADO ENTRE EL GRUPO FORMADO POR POLILACTIDO, POLIGLUCOLIDO, POLI(GLUCOLIDO LACTIDO), POLICAPROLACTONA Y DERIVADOS DE LOS MISMOS; Y EL POLIMERO HIDROFILO ES POLI(OXIDO DE ALQUILENO). UN FARMACO HIDROFOBO PUEDE INCORPORARSE CON FACILIDAD AL INTERIOR DE LA MICELA UTILIZANDO UN PROCEDIMIENTO SENCILLO PARA OBTENER UNA COMPOSICION DE FARMACO TERAPEUTICAMENTE EFICAZ.
ES96932066T 1995-09-21 1996-09-21 Compuesto medicamentoso de micela copolimera y metodo para su preparacion. Expired - Lifetime ES2188787T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019950030981A KR0180334B1 (ko) 1995-09-21 1995-09-21 블럭 공중합체 미셀을 이용한 약물전달체 및 이에 약물을 봉입하는 방법

Publications (1)

Publication Number Publication Date
ES2188787T3 true ES2188787T3 (es) 2003-07-01

Family

ID=19427413

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96932066T Expired - Lifetime ES2188787T3 (es) 1995-09-21 1996-09-21 Compuesto medicamentoso de micela copolimera y metodo para su preparacion.

Country Status (11)

Country Link
US (1) US6322805B1 (es)
EP (1) EP0854731B1 (es)
JP (1) JP3634377B2 (es)
KR (1) KR0180334B1 (es)
CN (1) CN1214818C (es)
AU (1) AU699988B2 (es)
CA (1) CA2231886C (es)
DE (1) DE69625921T2 (es)
ES (1) ES2188787T3 (es)
MX (1) MX9802156A (es)
WO (1) WO1997010849A1 (es)

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CA2231886C (en) 2002-03-19
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EP0854731A1 (en) 1998-07-29
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US6322805B1 (en) 2001-11-27
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