ES2189059T3 - Nuevo preparado para la administracion parenteral de la talidomida y procedimiento para su preparacion. - Google Patents
Nuevo preparado para la administracion parenteral de la talidomida y procedimiento para su preparacion.Info
- Publication number
- ES2189059T3 ES2189059T3 ES98117718T ES98117718T ES2189059T3 ES 2189059 T3 ES2189059 T3 ES 2189059T3 ES 98117718 T ES98117718 T ES 98117718T ES 98117718 T ES98117718 T ES 98117718T ES 2189059 T3 ES2189059 T3 ES 2189059T3
- Authority
- ES
- Spain
- Prior art keywords
- talidomide
- procedure
- preparation
- parenteral administration
- new prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- UEJJHQNACJXSKW-UHFFFAOYSA-N 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione Chemical compound O=C1C2=CC=CC=C2C(=O)N1C1CCC(=O)NC1=O UEJJHQNACJXSKW-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000007911 parenteral administration Methods 0.000 title 1
- 239000000243 solution Substances 0.000 abstract 2
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Abstract
SE DESCRIBE UNA SOLUCION ACUOSA DE TALIDOMIDA, QUE ES APROPIADA PARA SU INYECCION PARENTERAL, EN PARTICULAR INTRAVENOSA DE LA TALIDOMIDA PARA LA TERAPIA DE ENFERMEDADES INMUNOLOGICAS, ASI COMO UN PROCEDIMIENTO PARA LA PREPARACION DE LA CORRESPONDIENTE SOLUCION DE TALIDOMIDA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19743968A DE19743968C2 (de) | 1997-10-06 | 1997-10-06 | Intravenöse Applikationsform von Thalidomid zur Therapie immunologischer Erkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2189059T3 true ES2189059T3 (es) | 2003-07-01 |
Family
ID=7844650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98117718T Expired - Lifetime ES2189059T3 (es) | 1997-10-06 | 1998-09-18 | Nuevo preparado para la administracion parenteral de la talidomida y procedimiento para su preparacion. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6124322A (es) |
| EP (1) | EP0908176B1 (es) |
| JP (1) | JPH11189534A (es) |
| AT (1) | ATE229323T1 (es) |
| AU (1) | AU732634B2 (es) |
| CA (1) | CA2248838A1 (es) |
| DE (2) | DE19743968C2 (es) |
| DK (1) | DK0908176T3 (es) |
| ES (1) | ES2189059T3 (es) |
| HU (1) | HUP9802206A1 (es) |
| NZ (1) | NZ331563A (es) |
| PT (1) | PT908176E (es) |
| SI (1) | SI0908176T1 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6423321B2 (en) | 1999-02-24 | 2002-07-23 | Edward L. Tobinick | Cytokine antagonists for the treatment of sensorineural hearing loss |
| PT1040838E (pt) * | 1999-03-31 | 2003-08-29 | Gruenenthal Gmbh | Solucao aquosa estavel de 3-(1-oxo-1,3-di-hidro-isoindol-2-il)piperidino-2,6-diona |
| US7629360B2 (en) * | 1999-05-07 | 2009-12-08 | Celgene Corporation | Methods for the treatment of cachexia and graft v. host disease |
| WO2000072836A2 (en) * | 1999-05-27 | 2000-12-07 | The Rockefeller University | Methods of promoting or enhancing interleukin-12 production through administration of thalidomide |
| US7276249B2 (en) | 2002-05-24 | 2007-10-02 | Elan Pharma International, Ltd. | Nanoparticulate fibrate formulations |
| GB2371767A (en) * | 2001-02-02 | 2002-08-07 | Labman Automation Ltd | Dissolving materials by application of agitation and ultrasound |
| EP1389203B8 (en) | 2001-02-27 | 2010-03-10 | The Governement of the United States of America, represented by The Secretary Department of Health and Human services | Analogs of thalidomide as angiogenesis inhibitors |
| US8952895B2 (en) | 2011-06-03 | 2015-02-10 | Apple Inc. | Motion-based device operations |
| CA2808646C (en) | 2003-09-17 | 2016-08-23 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Thalidomide analogs as tnf-alpha modulators |
| US20050182097A1 (en) * | 2003-12-30 | 2005-08-18 | Zeldis Jerome B. | Methods and compositions using thalidomide for the treatment and management of central nervous system disorders or diseases |
| WO2005102345A1 (en) * | 2004-03-30 | 2005-11-03 | Alcon, Inc. | Use of rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance |
| US20060270707A1 (en) * | 2005-05-24 | 2006-11-30 | Zeldis Jerome B | Methods and compositions using 4-[(cyclopropanecarbonylamino)methyl]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione for the treatment or prevention of cutaneous lupus |
| US20090137631A1 (en) * | 2007-11-22 | 2009-05-28 | National Yang-Ming University | Methods and pharmaceutical compositions for regulation of g- and/or gc-rich nucleic acid expression |
| US8927725B2 (en) | 2011-12-02 | 2015-01-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Thio compounds |
| JP2022529720A (ja) * | 2019-04-22 | 2022-06-23 | スタートン セラピューティクス インコーポレイテッド | レナリドミドまたは他の免疫調節剤の持続投与 |
| EP4251131A1 (en) | 2021-01-08 | 2023-10-04 | Starton Therapeutics, Inc. | Stable solutions of immunomodulatory imide compounds for parenteral use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1531492A (en) * | 1991-02-14 | 1992-09-15 | Rockefeller University, The | Method for controlling abnormal concentration tnf alpha in human tissues |
| AU661299B2 (en) * | 1991-04-17 | 1995-07-20 | Grunenthal Gmbh | New thalidomide derivatives, method of manufacture and use thereof in medicaments |
| US5434170A (en) * | 1993-12-23 | 1995-07-18 | Andrulis Pharmaceuticals Corp. | Method for treating neurocognitive disorders |
| DE19613976C1 (de) * | 1996-04-09 | 1997-11-20 | Gruenenthal Gmbh | Thalidomid-Prodrugs mit immunmodulatorischer Wirkung |
-
1997
- 1997-10-06 DE DE19743968A patent/DE19743968C2/de not_active Expired - Fee Related
-
1998
- 1998-08-26 NZ NZ331563A patent/NZ331563A/xx unknown
- 1998-09-18 EP EP98117718A patent/EP0908176B1/de not_active Expired - Lifetime
- 1998-09-18 ES ES98117718T patent/ES2189059T3/es not_active Expired - Lifetime
- 1998-09-18 DE DE59806612T patent/DE59806612D1/de not_active Expired - Fee Related
- 1998-09-18 DK DK98117718T patent/DK0908176T3/da active
- 1998-09-18 SI SI9830278T patent/SI0908176T1/xx unknown
- 1998-09-18 PT PT98117718T patent/PT908176E/pt unknown
- 1998-09-18 AT AT98117718T patent/ATE229323T1/de not_active IP Right Cessation
- 1998-10-02 CA CA002248838A patent/CA2248838A1/en not_active Abandoned
- 1998-10-02 AU AU87925/98A patent/AU732634B2/en not_active Ceased
- 1998-10-05 HU HU9802206A patent/HUP9802206A1/hu unknown
- 1998-10-05 JP JP10282834A patent/JPH11189534A/ja not_active Withdrawn
- 1998-10-06 US US09/166,953 patent/US6124322A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE19743968A1 (de) | 1999-04-15 |
| PT908176E (pt) | 2003-04-30 |
| CA2248838A1 (en) | 1999-04-06 |
| US6124322A (en) | 2000-09-26 |
| DE19743968C2 (de) | 2002-07-11 |
| ATE229323T1 (de) | 2002-12-15 |
| DK0908176T3 (da) | 2003-01-06 |
| NZ331563A (en) | 1999-01-28 |
| HUP9802206A1 (hu) | 2000-12-28 |
| HK1018591A1 (en) | 1999-12-30 |
| HU9802206D0 (en) | 1998-11-30 |
| JPH11189534A (ja) | 1999-07-13 |
| AU8792598A (en) | 1999-04-22 |
| SI0908176T1 (en) | 2003-04-30 |
| EP0908176A1 (de) | 1999-04-14 |
| EP0908176B1 (de) | 2002-12-11 |
| DE59806612D1 (de) | 2003-01-23 |
| AU732634B2 (en) | 2001-04-26 |
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