ES2190528T3 - Composiciones que contienen vx478 y un compuesto de vitamina e soluble en agua, tal como vitamina e-tpgs. - Google Patents
Composiciones que contienen vx478 y un compuesto de vitamina e soluble en agua, tal como vitamina e-tpgs.Info
- Publication number
- ES2190528T3 ES2190528T3 ES97914287T ES97914287T ES2190528T3 ES 2190528 T3 ES2190528 T3 ES 2190528T3 ES 97914287 T ES97914287 T ES 97914287T ES 97914287 T ES97914287 T ES 97914287T ES 2190528 T3 ES2190528 T3 ES 2190528T3
- Authority
- ES
- Spain
- Prior art keywords
- vitamin
- tpgs
- soluble
- composite
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- AOBORMOPSGHCAX-UHFFFAOYSA-N Tocophersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-UHFFFAOYSA-N 0.000 title 1
- XLYOFNOQVPJJNP-PWCQTSIFSA-N Tritiated water Chemical compound [3H]O[3H] XLYOFNOQVPJJNP-PWCQTSIFSA-N 0.000 title 1
- 239000002131 composite material Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical compound O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- UKJLNMAFNRKWGR-UHFFFAOYSA-N cyclohexatrienamine Chemical group NC1=CC=C=C[CH]1 UKJLNMAFNRKWGR-UHFFFAOYSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000004030 hiv protease inhibitor Substances 0.000 abstract 1
- 238000013160 medical therapy Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
FORMULAS FARMACEUTICAS QUE CONTIENEN INHIBIDORES DE LA PROTEASA DEL VIH, ESPECIFICAMENTE INCLUYE ACIDO 3S-[3R*(1R,2S*)] - [3-[[(4AMINOFENILO)SULFONILO]2-METIPROPILO)-AMINO]-2-HIDROXI-1FENILMETILO)PROPIL]CARBAMICO, TETRAHIDRO-3-FURANILO ESTER (TAMBIEN CONOCIDO COMO VX 478 O 147W94) Y TOCOFEROL. SE DESCRIBE SU EMPLEO EN LA TERAPIA MEDICA.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1389396P | 1996-03-22 | 1996-03-22 | |
| GBGB9606372.2A GB9606372D0 (en) | 1996-03-26 | 1996-03-26 | Pharmaceutical formulations |
| US08/820,848 US6730679B1 (en) | 1996-03-22 | 1997-03-20 | Pharmaceutical formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2190528T3 true ES2190528T3 (es) | 2003-08-01 |
Family
ID=27268205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97914287T Expired - Lifetime ES2190528T3 (es) | 1996-03-22 | 1997-03-21 | Composiciones que contienen vx478 y un compuesto de vitamina e soluble en agua, tal como vitamina e-tpgs. |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0906107B1 (es) |
| CN (1) | CN1225587A (es) |
| AP (1) | AP1150A (es) |
| AT (1) | ATE230602T1 (es) |
| AU (1) | AU724239B2 (es) |
| BR (1) | BR9708238A (es) |
| CA (1) | CA2249336C (es) |
| CY (1) | CY2444B1 (es) |
| CZ (1) | CZ289958B6 (es) |
| DE (1) | DE69718315T2 (es) |
| DK (1) | DK0906107T3 (es) |
| EA (1) | EA001484B1 (es) |
| EE (1) | EE04093B1 (es) |
| ES (1) | ES2190528T3 (es) |
| GE (1) | GEP20012464B (es) |
| IS (1) | IS2066B (es) |
| NO (1) | NO317639B1 (es) |
| NZ (1) | NZ331645A (es) |
| RO (1) | RO119923B1 (es) |
| SI (1) | SI0906107T1 (es) |
| SK (1) | SK284244B6 (es) |
| TR (1) | TR199801881T2 (es) |
| UY (1) | UY25926A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114366808B (zh) * | 2021-12-14 | 2023-10-13 | 南京农业大学 | 一种多糖和病毒抗原共递送纳米疫苗、其制备方法及应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IS2334B (is) * | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
| GB9409778D0 (en) * | 1994-05-16 | 1994-07-06 | Dumex Ltd As | Compositions |
| WO1996036316A1 (en) * | 1995-05-19 | 1996-11-21 | Abbott Laboratories | Self-emulsifying formulations of lipophilic drugs |
-
1997
- 1997-03-21 AU AU21591/97A patent/AU724239B2/en not_active Expired
- 1997-03-21 TR TR1998/01881T patent/TR199801881T2/xx unknown
- 1997-03-21 DK DK97914287T patent/DK0906107T3/da active
- 1997-03-21 DE DE69718315T patent/DE69718315T2/de not_active Expired - Lifetime
- 1997-03-21 ES ES97914287T patent/ES2190528T3/es not_active Expired - Lifetime
- 1997-03-21 EP EP97914287A patent/EP0906107B1/en not_active Expired - Lifetime
- 1997-03-21 BR BR9708238A patent/BR9708238A/pt not_active IP Right Cessation
- 1997-03-21 SK SK1269-98A patent/SK284244B6/sk not_active IP Right Cessation
- 1997-03-21 AT AT97914287T patent/ATE230602T1/de active
- 1997-03-21 RO RO98-01407A patent/RO119923B1/ro unknown
- 1997-03-21 CN CN97193229A patent/CN1225587A/zh active Pending
- 1997-03-21 SI SI9730498T patent/SI0906107T1/xx unknown
- 1997-03-21 AP APAP/P/1998/001343A patent/AP1150A/en active
- 1997-03-21 GE GEAP19974496A patent/GEP20012464B/en unknown
- 1997-03-21 NZ NZ331645A patent/NZ331645A/en not_active IP Right Cessation
- 1997-03-21 EA EA199800755A patent/EA001484B1/ru not_active IP Right Cessation
- 1997-03-21 EE EE9800323A patent/EE04093B1/xx unknown
- 1997-03-21 CA CA002249336A patent/CA2249336C/en not_active Expired - Lifetime
- 1997-03-21 CZ CZ19983035A patent/CZ289958B6/cs not_active IP Right Cessation
-
1998
- 1998-08-28 IS IS4840A patent/IS2066B/xx unknown
- 1998-09-21 NO NO19984386A patent/NO317639B1/no not_active IP Right Cessation
-
2000
- 2000-01-17 UY UY25926A patent/UY25926A1/es not_active Application Discontinuation
-
2004
- 2004-06-23 CY CY0400050A patent/CY2444B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TR199801881T2 (xx) | 1999-01-18 |
| DE69718315D1 (de) | 2003-02-13 |
| AU2159197A (en) | 1997-10-17 |
| CN1225587A (zh) | 1999-08-11 |
| DE69718315T2 (de) | 2003-10-30 |
| CZ289958B6 (cs) | 2002-05-15 |
| RO119923B1 (ro) | 2005-06-30 |
| HK1016896A1 (en) | 1999-11-12 |
| CY2444B1 (en) | 2004-11-12 |
| EE9800323A (et) | 1999-04-15 |
| AU724239B2 (en) | 2000-09-14 |
| NO317639B1 (no) | 2004-11-29 |
| EP0906107B1 (en) | 2003-01-08 |
| CA2249336A1 (en) | 1997-10-02 |
| GEP20012464B (en) | 2001-06-25 |
| AP1150A (en) | 2003-03-14 |
| ATE230602T1 (de) | 2003-01-15 |
| DK0906107T3 (da) | 2003-05-05 |
| UY25926A1 (es) | 2000-09-29 |
| NZ331645A (en) | 2000-02-28 |
| IS2066B (is) | 2005-11-15 |
| CZ303598A3 (cs) | 1999-03-17 |
| EA001484B1 (ru) | 2001-04-23 |
| EP0906107A1 (en) | 1999-04-07 |
| CA2249336C (en) | 2005-11-22 |
| EA199800755A1 (ru) | 1999-06-24 |
| SK126998A3 (en) | 1999-10-08 |
| NO984386D0 (no) | 1998-09-21 |
| EE04093B1 (et) | 2003-08-15 |
| SI0906107T1 (en) | 2003-08-31 |
| AP9801343A0 (en) | 1998-09-30 |
| SK284244B6 (sk) | 2004-12-01 |
| NO984386L (no) | 1998-11-20 |
| IS4840A (is) | 1998-08-28 |
| BR9708238A (pt) | 1999-08-03 |
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