ES2191367T3 - Hidratos de carbono, utiles en los sistemas solidos de liberacion. - Google Patents

Hidratos de carbono, utiles en los sistemas solidos de liberacion.

Info

Publication number
ES2191367T3
ES2191367T3 ES98965297T ES98965297T ES2191367T3 ES 2191367 T3 ES2191367 T3 ES 2191367T3 ES 98965297 T ES98965297 T ES 98965297T ES 98965297 T ES98965297 T ES 98965297T ES 2191367 T3 ES2191367 T3 ES 2191367T3
Authority
ES
Spain
Prior art keywords
solid
carbohydrates
systems
liberation
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98965297T
Other languages
English (en)
Inventor
Julian Alexander Blair
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quadrant Drug Delivery Ltd
Original Assignee
Elan Drug Delivery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Drug Delivery Ltd filed Critical Elan Drug Delivery Ltd
Application granted granted Critical
Publication of ES2191367T3 publication Critical patent/ES2191367T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Composición en forma de una matriz sólida que tiene una sustancia incorporada en la misma, comprendiendo dicha matriz un hidrato de carbono sustituido que tiene la estructura definida por cualquiera de las fórmulas 1 a 4 **(Fórmula)** en las que uno o más de R1-R8 son independientemente NHR9, N(R9)2, O(C=O)R9 ó OR9, en los que R9 es un grupo hidrocarbonado ramificado C3-C8; y cualquier R1-R8 restante es independientemente H, NHR10, N(R10)2, (C=O)R10 ó OR10, en los que R10 es un grupo alquilo de cadena lineal C1-C4.
ES98965297T 1997-12-23 1998-12-23 Hidratos de carbono, utiles en los sistemas solidos de liberacion. Expired - Lifetime ES2191367T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6875497P 1997-12-23 1997-12-23

Publications (1)

Publication Number Publication Date
ES2191367T3 true ES2191367T3 (es) 2003-09-01

Family

ID=22084508

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98965297T Expired - Lifetime ES2191367T3 (es) 1997-12-23 1998-12-23 Hidratos de carbono, utiles en los sistemas solidos de liberacion.

Country Status (12)

Country Link
US (2) US6352722B1 (es)
EP (1) EP1042339B1 (es)
JP (1) JP2001527087A (es)
AT (1) ATE235503T1 (es)
AU (1) AU2062999A (es)
CA (1) CA2316275A1 (es)
DE (1) DE69812711T2 (es)
DK (1) DK1042339T3 (es)
ES (1) ES2191367T3 (es)
PT (1) PT1042339E (es)
WO (1) WO1999033853A2 (es)
ZA (1) ZA9811843B (es)

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Also Published As

Publication number Publication date
DE69812711D1 (de) 2003-04-30
WO1999033853A2 (en) 1999-07-08
ZA9811843B (en) 1999-06-24
EP1042339A2 (en) 2000-10-11
PT1042339E (pt) 2003-07-31
ATE235503T1 (de) 2003-04-15
US6352722B1 (en) 2002-03-05
CA2316275A1 (en) 1999-07-08
US20020058067A1 (en) 2002-05-16
WO1999033853A3 (en) 1999-09-30
DE69812711T2 (de) 2003-11-06
JP2001527087A (ja) 2001-12-25
AU2062999A (en) 1999-07-19
DK1042339T3 (da) 2003-07-21
EP1042339B1 (en) 2003-03-26

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