ES2192859T3 - Procedimiento para la produccion de microparticulas esfericas con superficie lisa, las cuales estan compuestas total o parcialmente por al menos un polisacarido lineal insoluble en agua asi como microparticulas obtenibles con este procedimiento. - Google Patents

Procedimiento para la produccion de microparticulas esfericas con superficie lisa, las cuales estan compuestas total o parcialmente por al menos un polisacarido lineal insoluble en agua asi como microparticulas obtenibles con este procedimiento.

Info

Publication number
ES2192859T3
ES2192859T3 ES99944385T ES99944385T ES2192859T3 ES 2192859 T3 ES2192859 T3 ES 2192859T3 ES 99944385 T ES99944385 T ES 99944385T ES 99944385 T ES99944385 T ES 99944385T ES 2192859 T3 ES2192859 T3 ES 2192859T3
Authority
ES
Spain
Prior art keywords
procedure
microparticles
smooth surface
production
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99944385T
Other languages
English (en)
Inventor
Holger Bengs
Jurgen Grande
Silke Schuth
Gitte Bohm
Arnold Schneller
Anette Brunner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Celanese Ventures GmbH
Original Assignee
Celanese Ventures GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celanese Ventures GmbH filed Critical Celanese Ventures GmbH
Application granted granted Critical
Publication of ES2192859T3 publication Critical patent/ES2192859T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C08J3/14—Powdering or granulating by precipitation from solutions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L3/00—Compositions of starch, amylose or amylopectin or of their derivatives or degradation products
    • C08L3/12—Amylose; Amylopectin; Degradation products thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

Procedimiento para la producción de micropartículas esféricas con superficie lisa, significando superficie lisa que la profundidad de las irregularidades sobre la superficie de las partículas es de un máximo de 10 % del diámetro medio de las partículas, que están compuestas total o parcialmente por al menos un polisacárido lineal insoluble en agua que queda bajo las clases 5-7 según la definición de la farmacopea alemana, mediante disolución de al menos un polisacárido lineal insoluble en agua en un disolvente o mezcla de disolventes, incorporación de la solución a un agente precipitante o mezcla de agentes precipitantes, eventual enfriamiento de la mezcla con esto originada y separación de las micropartículas formadas, empleándose como agente coadyuvante de precipitación al menos un derivado de celulosa soluble en agua.
ES99944385T 1998-08-28 1999-08-13 Procedimiento para la produccion de microparticulas esfericas con superficie lisa, las cuales estan compuestas total o parcialmente por al menos un polisacarido lineal insoluble en agua asi como microparticulas obtenibles con este procedimiento. Expired - Lifetime ES2192859T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19839214A DE19839214C1 (de) 1998-08-28 1998-08-28 Verfahren zur Herstellung von sphärischen Mikropartikeln mit glatter Oberfläche, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen, sowie mit diesem Verfahren erhältliche Mikropartikel und deren Verwendung

Publications (1)

Publication Number Publication Date
ES2192859T3 true ES2192859T3 (es) 2003-10-16

Family

ID=7879048

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99944385T Expired - Lifetime ES2192859T3 (es) 1998-08-28 1999-08-13 Procedimiento para la produccion de microparticulas esfericas con superficie lisa, las cuales estan compuestas total o parcialmente por al menos un polisacarido lineal insoluble en agua asi como microparticulas obtenibles con este procedimiento.

Country Status (9)

Country Link
US (1) US6723429B2 (es)
EP (1) EP1124896B1 (es)
JP (1) JP2002523599A (es)
CN (1) CN1178980C (es)
AU (1) AU5734099A (es)
CA (1) CA2341904A1 (es)
DE (2) DE19839214C1 (es)
ES (1) ES2192859T3 (es)
WO (1) WO2000012617A1 (es)

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DE19737481A1 (de) * 1997-08-28 1999-03-04 Hoechst Ag Sphärische lineare Polysaccharide enthaltende Mikropartikel
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DE19902917C2 (de) * 1999-01-26 2001-03-29 Aventis Res & Tech Gmbh & Co Wasserunlösliche lineare Polysaccharide zur Filtration
WO2007001448A2 (en) 2004-11-04 2007-01-04 Massachusetts Institute Of Technology Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
WO2007070682A2 (en) 2005-12-15 2007-06-21 Massachusetts Institute Of Technology System for screening particles
CA2648099C (en) * 2006-03-31 2012-05-29 The Brigham And Women's Hospital, Inc System for targeted delivery of therapeutic agents
JP5630998B2 (ja) 2006-05-15 2014-11-26 マサチューセッツ インスティテュート オブ テクノロジー 機能的粒子のためのポリマー
WO2007150030A2 (en) * 2006-06-23 2007-12-27 Massachusetts Institute Of Technology Microfluidic synthesis of organic nanoparticles
WO2008019142A2 (en) * 2006-08-04 2008-02-14 Massachusetts Institute Of Technology Oligonucleotide systems for targeted intracellular delivery
EP2134830A2 (en) 2007-02-09 2009-12-23 Massachusetts Institute of Technology Oscillating cell culture bioreactor
JP2010523595A (ja) * 2007-04-04 2010-07-15 マサチューセッツ インスティテュート オブ テクノロジー ポリ（アミノ酸）ターゲッティング部分
US20090022805A1 (en) * 2007-06-28 2009-01-22 Joram Slager Polypeptide microparticles having sustained release characteristics, methods and uses
WO2009005709A1 (en) * 2007-06-28 2009-01-08 Surmodics, Inc. Polypeptide microparticles
JP2011500569A (ja) 2007-10-12 2011-01-06 マサチューセッツ インスティテュート オブ テクノロジー ワクチンナノテクノロジー
US8277812B2 (en) 2008-10-12 2012-10-02 Massachusetts Institute Of Technology Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
US8591905B2 (en) 2008-10-12 2013-11-26 The Brigham And Women's Hospital, Inc. Nicotine immunonanotherapeutics
US8343498B2 (en) 2008-10-12 2013-01-01 Massachusetts Institute Of Technology Adjuvant incorporation in immunonanotherapeutics
US8343497B2 (en) 2008-10-12 2013-01-01 The Brigham And Women's Hospital, Inc. Targeting of antigen presenting cells with immunonanotherapeutics
US8592574B2 (en) 2009-01-22 2013-11-26 Quegen Biotech Co., Ltd. Beta-glucan-based scaffold for biological tissue engineering using radiation fusion technology, and production method therefor
WO2010085119A2 (ko) * 2009-01-22 2010-07-29 주식회사 큐젠바이오텍 방사선 융합 기술을 이용한 생체조직공학용 베타-글루칸 기반 지지체 및 이의 제조방법
BRPI1012036A2 (pt) 2009-05-27 2017-10-10 Selecta Biosciences Inc nanocarreadores que possuem componentes com diferentes taxas de liberação
CA2798739A1 (en) 2010-05-26 2011-12-01 Selecta Biosciences, Inc. Nanocarrier compositions with uncoupled adjuvant
EA201390660A1 (ru) 2010-11-05 2013-11-29 Селекта Байосайенсиз, Инк. Модифицированные никотиновые соединения и связанные способы
KR20140050698A (ko) 2011-07-29 2014-04-29 셀렉타 바이오사이언시즈, 인크. 체액성 및 세포독성 t 림프구(ctl) 면역 반응을 발생시키는 합성 나노운반체
TWI565801B (zh) 2011-10-05 2017-01-11 杜邦股份有限公司 用於製備多醣纖維之新穎組成物
CA2851312A1 (en) * 2011-10-05 2013-04-11 E.I. Du Pont De Nemours And Company Novel composition for preparing polysaccharide fibers
CN106103551A (zh) 2014-01-06 2016-11-09 纳幕尔杜邦公司 聚α‑1,3‑葡聚糖膜的制备
US10106626B2 (en) 2014-01-17 2018-10-23 Ei Du Pont De Nemours And Company Production of poly alpha-1,3-glucan formate films
CN112639004B (zh) * 2018-09-04 2023-06-16 信越化学工业株式会社 纤维素组合物、纤维素成型体以及纤维素组合物的制造方法
CN109400921B (zh) * 2018-11-14 2021-06-15 绍兴文理学院 一种超细乙基纤维素粒子的制备方法

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Also Published As

Publication number Publication date
US20010051716A1 (en) 2001-12-13
CN1178980C (zh) 2004-12-08
DE19839214C1 (de) 2000-05-25
WO2000012617A1 (de) 2000-03-09
DE59904877D1 (de) 2003-05-08
AU5734099A (en) 2000-03-21
EP1124896A1 (de) 2001-08-22
JP2002523599A (ja) 2002-07-30
CA2341904A1 (en) 2000-03-09
CN1317035A (zh) 2001-10-10
EP1124896B1 (de) 2003-04-02
US6723429B2 (en) 2004-04-20

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