ES2193424T3 - Aminas triciclicas farmaceuticamente activas. - Google Patents

Aminas triciclicas farmaceuticamente activas.

Info

Publication number
ES2193424T3
ES2193424T3 ES97955063T ES97955063T ES2193424T3 ES 2193424 T3 ES2193424 T3 ES 2193424T3 ES 97955063 T ES97955063 T ES 97955063T ES 97955063 T ES97955063 T ES 97955063T ES 2193424 T3 ES2193424 T3 ES 2193424T3
Authority
ES
Spain
Prior art keywords
tricycle
amines
pharmaceutically active
pirimido
indoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97955063T
Other languages
English (en)
Inventor
Gordon L Bundy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Application granted granted Critical
Publication of ES2193424T3 publication Critical patent/ES2193424T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Cosmetics (AREA)

Abstract

LA INVENCION SE REFIERE A PIRIMIDO[4,5-B]INDOLES (IV) Y A SALES DE PIRIMIDO[4,5-B]INDOLES (V), UTILES PARA EL TRATAMIENTO DEL ASMA, ASI COMO A PROCEDIMIENTOS PARA LA PREPARACION DE LAS MISMAS.
ES97955063T 1997-01-08 1997-12-19 Aminas triciclicas farmaceuticamente activas. Expired - Lifetime ES2193424T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3522397P 1997-01-08 1997-01-08
US4374997P 1997-04-09 1997-04-09

Publications (1)

Publication Number Publication Date
ES2193424T3 true ES2193424T3 (es) 2003-11-01

Family

ID=26711898

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97955063T Expired - Lifetime ES2193424T3 (es) 1997-01-08 1997-12-19 Aminas triciclicas farmaceuticamente activas.

Country Status (22)

Country Link
US (1) US5932728A (es)
EP (1) EP0964865B1 (es)
JP (1) JP2002511061A (es)
KR (1) KR20000069940A (es)
CN (1) CN1128798C (es)
AT (1) ATE233763T1 (es)
AU (1) AU723709B2 (es)
CA (1) CA2275389A1 (es)
CZ (1) CZ288076B6 (es)
DE (1) DE69719563T2 (es)
DK (1) DK0964865T3 (es)
ES (1) ES2193424T3 (es)
FI (1) FI991568L (es)
HU (1) HUP0003692A3 (es)
NO (1) NO312463B1 (es)
NZ (1) NZ336659A (es)
PL (1) PL334451A1 (es)
PT (1) PT964865E (es)
RU (1) RU2200737C2 (es)
SI (1) SI0964865T1 (es)
SK (1) SK283378B6 (es)
WO (1) WO1998042708A2 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020147216A1 (en) * 2000-01-31 2002-10-10 Yuhong Zhou Mucin synthesis inhibitors
US7345051B2 (en) 2000-01-31 2008-03-18 Genaera Corporation Mucin synthesis inhibitors
ES2282235T3 (es) 2000-01-31 2007-10-16 Genaera Corporation Inhibidores de la sintesis de la mucina.
EP1442039A1 (en) * 2001-10-31 2004-08-04 Bayer HealthCare AG Pyrimido (4,5-b) indole derivatives
AU2003300522A1 (en) * 2002-12-27 2004-07-22 Bayer Healthcare Ag 4-phenyl-pyrimido (4,5-b) indole derivatives
US8431538B2 (en) * 2009-07-22 2013-04-30 The Board Of Trustees Of The University Of Illinois HDAC inhibitors and therapeutic methods of using same
US9732083B2 (en) 2011-03-15 2017-08-15 Merck Sharp & Dohme Corp. Tricyclic gyrase inhibitors
PT2807165T (pt) 2012-01-27 2019-07-12 Univ Montreal Derivados de pirimido[4,5-b]indole e sua utilização na expansão de células estaminais hematopoiéticas
EP3303570B1 (en) 2015-06-05 2021-01-20 Héma-Québec Methods for culturing and/or differentiating hematopoietic stem cells into progenitors and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5502187A (en) * 1992-04-03 1996-03-26 The Upjohn Company Pharmaceutically active bicyclic-heterocyclic amines
FI944602A0 (fi) * 1992-04-03 1994-10-03 Upjohn Co Farmaseuttisesti aktiiviset bisyklis-heterosykliset amiinit
US5795986A (en) * 1995-03-02 1998-08-18 Pharmacia & Upjohn Company Pyrimido 4,5-B!indoles

Also Published As

Publication number Publication date
ATE233763T1 (de) 2003-03-15
PT964865E (pt) 2003-06-30
SK283378B6 (sk) 2003-06-03
SI0964865T1 (en) 2003-08-31
AU8655498A (en) 1998-10-20
WO1998042708A3 (en) 1998-12-17
FI991568A7 (fi) 1999-07-08
EP0964865B1 (en) 2003-03-05
NO993359L (no) 1999-09-07
US5932728A (en) 1999-08-03
CZ238899A3 (cs) 1999-10-13
CZ288076B6 (cs) 2001-04-11
DK0964865T3 (da) 2003-05-05
JP2002511061A (ja) 2002-04-09
AU723709B2 (en) 2000-09-07
HUP0003692A3 (en) 2002-10-28
DE69719563T2 (de) 2003-11-27
WO1998042708A2 (en) 1998-10-01
NO993359D0 (no) 1999-07-07
KR20000069940A (ko) 2000-11-25
EP0964865A2 (en) 1999-12-22
CN1128798C (zh) 2003-11-26
FI991568L (fi) 1999-07-08
DE69719563D1 (de) 2003-04-10
NO312463B1 (no) 2002-05-13
HK1023344A1 (en) 2000-09-08
PL334451A1 (en) 2000-02-28
NZ336659A (en) 2001-01-26
CN1239961A (zh) 1999-12-29
SK90199A3 (en) 2000-05-16
HUP0003692A2 (hu) 2001-04-28
RU2200737C2 (ru) 2003-03-20
CA2275389A1 (en) 1998-10-01

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