ES2194110T3 - Nuevas composiciones embolizantes. - Google Patents

Nuevas composiciones embolizantes.

Info

Publication number
ES2194110T3
ES2194110T3 ES96925568T ES96925568T ES2194110T3 ES 2194110 T3 ES2194110 T3 ES 2194110T3 ES 96925568 T ES96925568 T ES 96925568T ES 96925568 T ES96925568 T ES 96925568T ES 2194110 T3 ES2194110 T3 ES 2194110T3
Authority
ES
Spain
Prior art keywords
biocompatible
compositions
new
embolizing compositions
biocompatible polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96925568T
Other languages
English (en)
Inventor
Richard J Greff
Michael L Jones
Scott Evans
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micro Therapeutics Inc
Original Assignee
Micro Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/508,248 external-priority patent/US5580568A/en
Priority claimed from US08/507,863 external-priority patent/US5667767A/en
Application filed by Micro Therapeutics Inc filed Critical Micro Therapeutics Inc
Application granted granted Critical
Publication of ES2194110T3 publication Critical patent/ES2194110T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414—Particles, beads, capsules or spheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0409—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is not a halogenated organic compound
    • A61K49/0414—Particles, beads, capsules or spheres
    • A61K49/0419—Microparticles, microbeads, microcapsules, microspheres, i.e. having a size or diameter higher or equal to 1 micrometer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Materials Engineering (AREA)
  • Cardiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

SE DESCRIBEN NUEVAS COMPOSICIONES PARA EMBOLIZAR VASOS SANGUINEOS QUE RESULTAN PARTICULARMENTE ADECUADAS PARA TRATAR LESIONES VASCULARES MEDIANTE INTRODUCCION DE CATETERES. EN UNA REALIZACION, LAS COMPOSICIONES DE LA INVENCION INCLUYEN UN POLIMERO BIOCOMPATIBLE, UN DISOLVENTE BIOCOMPATIBLE Y UN AGENTE DE CONTRASTE INSOLUBLE EN AGUA BIOCOMPATIBLE QUE SE CARACTERIZA PORQUE PRESENTA UN TAMAÑO DE PARTICULA MEDIO MENOR QUE APROXIMADAMENTE 10 MI}M. EN OTRA REALIZACION, EL POLIMERO BIOCOMPATIBLE EN ESTAS COMPOSICIONES SE SUSTITUYE POR UN PREPOLIMERO BIOCOMPATIBLE.
ES96925568T 1995-07-27 1996-07-29 Nuevas composiciones embolizantes. Expired - Lifetime ES2194110T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/508,248 US5580568A (en) 1995-07-27 1995-07-27 Cellulose diacetate compositions for use in embolizing blood vessels
US08/507,863 US5667767A (en) 1995-07-27 1995-07-27 Compositions for use in embolizing blood vessels
EP96925568A EP0847240B1 (en) 1995-07-27 1996-07-29 Novel embolizing compositions

Publications (1)

Publication Number Publication Date
ES2194110T3 true ES2194110T3 (es) 2003-11-16

Family

ID=27238028

Family Applications (2)

Application Number Title Priority Date Filing Date
ES02075574T Expired - Lifetime ES2232711T3 (es) 1995-07-27 1996-07-29 Composiciones de embolizacion.
ES96925568T Expired - Lifetime ES2194110T3 (es) 1995-07-27 1996-07-29 Nuevas composiciones embolizantes.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES02075574T Expired - Lifetime ES2232711T3 (es) 1995-07-27 1996-07-29 Composiciones de embolizacion.

Country Status (9)

Country Link
EP (2) EP1208855B1 (es)
JP (1) JP4678895B2 (es)
CN (1) CN1079642C (es)
AT (2) ATE235268T1 (es)
AU (1) AU6604396A (es)
CA (1) CA2215356C (es)
DE (2) DE69626992T2 (es)
ES (2) ES2232711T3 (es)
WO (1) WO1997004657A1 (es)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2682797A (en) * 1996-05-31 1998-01-05 Micro Therapeutics, Inc. Methods for sterilizing female mammals
US6103254A (en) * 1996-05-31 2000-08-15 Micro Therapeutics, Inc. Methods for sterilizing male mammals
ATE230269T1 (de) 1996-05-31 2003-01-15 Micro Therapeutics Inc Zusammensetzungen zur verwendung bei der embolisierung von blutgefässen
ATE269121T1 (de) * 1996-07-29 2004-07-15 Micro Therapeutics Inc Kit aus drei glasfläschen zur vaskulären embolisierung unter verwendung eines dimethylsulfoxyd enthaltenden mittels
US5830178A (en) * 1996-10-11 1998-11-03 Micro Therapeutics, Inc. Methods for embolizing vascular sites with an emboilizing composition comprising dimethylsulfoxide
US5785642A (en) * 1996-10-18 1998-07-28 Micro Therapeutics, Inc. Methods for treating urinary incontinence in mammals
WO1998047532A1 (en) * 1997-04-24 1998-10-29 Nycomed Imaging As Embolus therapy using insoluble microparticles or vesicles containing contrast agents
US6569417B2 (en) 1997-10-10 2003-05-27 Micro Therapeutics, Inc. Methods for treating urinary incontinence in mammals
US6309420B1 (en) * 1997-10-14 2001-10-30 Parallax Medical, Inc. Enhanced visibility materials for implantation in hard tissue
US7572263B2 (en) 1998-04-01 2009-08-11 Arthrocare Corporation High pressure applicator
WO1999049819A1 (en) 1998-04-01 1999-10-07 Parallax Medical, Inc. Pressure applicator for hard tissue implant placement
US6238335B1 (en) 1998-12-11 2001-05-29 Enteric Medical Technologies, Inc. Method for treating gastroesophageal reflux disease and apparatus for use therewith
US7132582B2 (en) 2003-05-30 2006-11-07 Council Of Scientific And Industrial Research Catalytic process for the preparation of isolongifolene
US6251064B1 (en) 1998-12-11 2001-06-26 Enteric Medical Technologies, Inc. Method for creating valve-like mechanism in natural body passageway
US6303100B1 (en) * 1999-03-19 2001-10-16 Micro Therapeutics, Inc. Methods for inhibiting the formation of potential endoleaks associated with endovascular repair of abdominal aortic aneurysms
AU6168699A (en) 1999-03-24 2000-10-09 Parallax Medical, Inc. Non-compliant system for delivery of implant material
US6241719B1 (en) * 1999-05-13 2001-06-05 Micro Therapeutics, Inc. Method for forming a radioactive stent
EP1987847A1 (en) * 1999-05-21 2008-11-05 Micro Therapeutics, Inc. Novel high viscosity embolizing compositions
US6273916B1 (en) 1999-09-02 2001-08-14 Cook Incorporated Method and apparatus for strengthening vertebral bodies
US6783515B1 (en) 1999-09-30 2004-08-31 Arthrocare Corporation High pressure delivery system
DE60130544T2 (de) 2000-03-13 2008-06-26 Biocure, Inc. Embolische zusammensetzungen
US7459142B2 (en) 2002-06-06 2008-12-02 Micro Therapeutics, Inc. High viscosity embolizing compositions comprising prepolymers
US20050065434A1 (en) * 2003-09-22 2005-03-24 Bavaro Vincent P. Polymeric marker with high radiopacity for use in medical devices
CN100479865C (zh) * 2003-10-27 2009-04-22 玛丽亚·赫曼纳斯·吉哈德斯·斯德赫斯 空气处理方法和装置
US8048086B2 (en) * 2004-02-25 2011-11-01 Femasys Inc. Methods and devices for conduit occlusion
CN101890188B (zh) 2005-11-28 2012-11-14 独立行政法人科学技术振兴机构 用于制造体内留置型医疗器具的装置
CN100453125C (zh) * 2006-11-22 2009-01-21 山东赛克赛斯药业科技有限公司 非粘附性医用液体栓塞剂及其应用
JP2010515493A (ja) * 2007-01-12 2010-05-13 ヤンファン リー， Ｘ線不透過性生物分解微小球型血管栓塞材料
CN102100929B (zh) * 2010-08-27 2013-10-02 上海微创医疗器械（集团）有限公司 一种栓塞材料及其制备方法
CN102266591A (zh) * 2011-06-17 2011-12-07 微创医疗器械(上海)有限公司 一种基于胶原蛋白的新型液体栓塞材料及其制备方法
CN102552108B (zh) * 2012-01-17 2014-06-04 汤小国 一种液体栓塞剂及其制备方法
CN103126973B (zh) * 2013-02-01 2015-02-18 安徽四正医药科技有限公司 用于血管瘤治疗的多糖水凝胶液体栓塞剂及其制备方法
CA2925606A1 (en) * 2015-04-23 2016-10-23 Covidien Lp Resorbable oxidized cellulose embolization solution
CN108079366A (zh) * 2017-01-24 2018-05-29 珠海神平医疗科技有限公司 一种液体栓塞材料及其制备方法
CN107875436B (zh) * 2017-11-10 2020-02-18 杭州华微医疗科技有限公司 一种负载碳酸氢钠粉末的液体栓塞剂组合物及其应用
CN108785691A (zh) * 2018-07-06 2018-11-13 中南大学湘雅二医院 一种对微小病灶进行定位检测的人造结节及定位方法
CN110964131B (zh) 2018-09-29 2022-11-22 诺维新材有限公司 含有多羟基的聚合物及其制备方法和用途
AU2021338356A1 (en) * 2020-09-04 2023-04-06 Blackswan Vascular, Inc. Liquid embolic compositions with controlled release of radiopaque and therapeutic compounds and methods of using the same
US11801058B2 (en) * 2021-03-04 2023-10-31 Accumedical Beijing Ltd. Liquid embolic compositions
CN116407666A (zh) * 2021-12-31 2023-07-11 神泓医疗科技(上海)有限公司 液体栓塞剂及其制备方法和应用
CN114344551B (zh) * 2021-12-31 2023-06-16 神泓医疗科技(上海)有限公司 液体栓塞组合物及其应用、医疗介入器械和介入治疗药物
CN116407667A (zh) * 2021-12-31 2023-07-11 神泓医疗科技(上海)有限公司 液体栓塞剂及其制备方法和应用
CN116370694A (zh) * 2021-12-31 2023-07-04 神泓医疗科技(上海)有限公司 液体栓塞剂及其制备方法和应用
CN116785492A (zh) * 2022-03-14 2023-09-22 神泓医疗科技(上海)有限公司 液体栓塞剂及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4079124A (en) * 1976-04-21 1978-03-14 Medi-Physics, Inc. Method of preparing X-ray contrast media containing ores of hafnium, tantalum and tungsten
US4268495A (en) * 1979-01-08 1981-05-19 Ethicon, Inc. Injectable embolization and occlusion solution
WO1985000969A1 (en) * 1983-08-31 1985-03-14 S.K.Y. Polymers Ltd. Injectable physiologically acceptable polymeric compositions
US4795741A (en) * 1987-05-06 1989-01-03 Biomatrix, Inc. Compositions for therapeutic percutaneous embolization and the use thereof
DE69114782T2 (de) * 1990-08-08 1996-04-18 Takeda Chemical Industries Ltd Intravaskulär embolisierendes Mittel mit Gehalt an einem die Angiogenesis hemmenden Stoff.
JP3040551B2 (ja) * 1991-09-05 2000-05-15 株式会社カネカメディックス 人工塞栓形成用高分子溶液
JP3203382B2 (ja) * 1992-03-13 2001-08-27 国立循環器病センター総長 人工塞栓形成用高分子溶液
JP2736339B2 (ja) * 1992-09-30 1998-04-02 株式会社日本感光色素研究所 動脈瘤の液体塞栓材料
US5443454A (en) * 1992-12-09 1995-08-22 Terumo Kabushiki Kaisha Catheter for embolectomy

Also Published As

Publication number Publication date
EP0847240A1 (en) 1998-06-17
WO1997004657A1 (en) 1997-02-13
EP1208855B1 (en) 2004-12-15
DE69634056T2 (de) 2005-12-08
EP0847240B1 (en) 2003-03-26
CN1192654A (zh) 1998-09-09
AU6604396A (en) 1997-02-26
EP1208855A1 (en) 2002-05-29
ATE284715T1 (de) 2005-01-15
DE69626992T2 (de) 2003-12-18
DE69626992D1 (de) 2003-04-30
JP4678895B2 (ja) 2011-04-27
CA2215356A1 (en) 1997-02-13
EP0847240A4 (en) 2000-01-19
CA2215356C (en) 2009-08-25
CN1079642C (zh) 2002-02-27
JP2000505045A (ja) 2000-04-25
DE69634056D1 (de) 2005-01-20
ATE235268T1 (de) 2003-04-15
ES2232711T3 (es) 2005-06-01

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