ES2194222T3 - Dispositivo para la administracion asistida electricamente de agentes tales como lidocaina y epinefrina. - Google Patents

Dispositivo para la administracion asistida electricamente de agentes tales como lidocaina y epinefrina.

Info

Publication number
ES2194222T3
ES2194222T3 ES97946508T ES97946508T ES2194222T3 ES 2194222 T3 ES2194222 T3 ES 2194222T3 ES 97946508 T ES97946508 T ES 97946508T ES 97946508 T ES97946508 T ES 97946508T ES 2194222 T3 ES2194222 T3 ES 2194222T3
Authority
ES
Spain
Prior art keywords
lidocaine
electrically assisted
epinefrine
agents
assisted administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97946508T
Other languages
English (en)
Inventor
Andreas Linkwitz
Ivan W Chin
Richard J Gyory
Ronald V Thompson
Paul J Urbanski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21856113&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2194222(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2194222T3 publication Critical patent/ES2194222T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A FORMULACIONES PARA LA ADMINISTRACION TRANSDERMICA ELECTRICAMENTE ASISTIDA DE LIDOCAINA Y DE EPINEFRINA. LA INVENCION SUMINISTRA ADEMAS PROCEDIMIENTO Y DISPOSITIVOS PARA LA ADMINISTRACION ELECTRICAMENTE ASISTIDA DE ANESTESICOS LOCALES, PREFERIBLEMENTE LIDOCAINA.
ES97946508T 1996-11-14 1997-11-03 Dispositivo para la administracion asistida electricamente de agentes tales como lidocaina y epinefrina. Expired - Lifetime ES2194222T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3080096P 1996-11-14 1996-11-14

Publications (1)

Publication Number Publication Date
ES2194222T3 true ES2194222T3 (es) 2003-11-16

Family

ID=21856113

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97946508T Expired - Lifetime ES2194222T3 (es) 1996-11-14 1997-11-03 Dispositivo para la administracion asistida electricamente de agentes tales como lidocaina y epinefrina.

Country Status (12)

Country Link
EP (1) EP0941085B1 (es)
JP (1) JP2001505197A (es)
KR (1) KR100534512B1 (es)
CN (1) CN1155372C (es)
AT (1) ATE238046T1 (es)
AU (1) AU721114B2 (es)
CA (1) CA2271944C (es)
DE (1) DE69721293T2 (es)
DK (1) DK0941085T3 (es)
ES (1) ES2194222T3 (es)
PT (1) PT941085E (es)
WO (1) WO1998020869A2 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2297941T3 (es) 1998-11-02 2008-05-01 Alza Corporation Dispositivo de electrotransporte que comprende un agente antimicrobiano compatible.
WO2000030621A1 (fr) * 1998-11-26 2000-06-02 Hisamitsu Pharmaceutical Co., Inc. Composition de gel adhesif autocollant pour ionophorese et son appareil
US6629968B1 (en) 2000-06-30 2003-10-07 Vyteris, Inc. Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system incorporating the reservoir-electrode
JPWO2005020967A1 (ja) * 2003-08-29 2007-11-01 久光製薬株式会社 電気的薬物移送製剤
US20050228335A1 (en) 2004-04-07 2005-10-13 Reddy Vilambi N Physical, structural, mechanical, electrical and electromechanical features for use in association with electrically assisted delivery devices and systems
US20050228336A1 (en) * 2004-04-07 2005-10-13 Preston Keusch Electrically assisted lidocaine and epinephrine delivery device having extended shelf-stability
US20070093743A1 (en) 2005-09-30 2007-04-26 Vyteris, Inc. Iontophoresis Drug Delivery Device Providing Acceptable Depth and Duration of Dermal Anesthesia
WO2007041475A2 (en) * 2005-09-30 2007-04-12 Vyteris, Inc. Iontophoresis drug delivery formulation providing acceptable sensation and dermal anesthesia
JP5116482B2 (ja) 2005-11-14 2013-01-09 帝國製薬株式会社 イオントフォレーシス用製剤
CN102159205A (zh) 2008-06-25 2011-08-17 Fe3医学有限公司 用于经皮递送治疗有效量的铁的贴片和方法
GB0815051D0 (en) * 2008-08-18 2008-09-24 Univ Dundee Apparatus and method for mineralising biological materials
JP2012524604A (ja) * 2009-04-25 2012-10-18 インキューブ ラブズ， エルエルシー キレート剤の経皮的イオン導入送達のための方法
US8821945B2 (en) 2009-04-25 2014-09-02 Fe3 Medical, Inc. Method for transdermal iontophoretic delivery of chelated agents
US8628805B2 (en) 2009-06-04 2014-01-14 Alk Ag Stabilized composition comprising at least one adrenergic compound
WO2010139752A2 (en) 2009-06-04 2010-12-09 Alk Ag Stabilised composition comprising at least one adrenergic compound
US9119876B1 (en) * 2015-03-13 2015-09-01 Par Pharmaceutical, Inc. Epinephrine formulations
US20170189352A1 (en) 2015-03-13 2017-07-06 Par Pharmaceutical, Inc. Epinephrine formulations
WO2018039420A1 (en) * 2016-08-25 2018-03-01 Imprimis Pharmaceuticals, Inc. Epinephrine-based ophthalmic compositions for intraocular administration and methods for fabricating thereof
EP3687475A4 (en) 2017-09-26 2021-07-28 YS Pharmtech STABILIZATION OF EPINEPHRIN FORMULATIONS
JP2020536926A (ja) 2017-10-10 2020-12-17 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ Ｌ−エピネフリンの安定化注射用医薬用組成物
CA3093725C (en) 2018-03-23 2021-08-24 Nevakar Inc. Epinephrine compositions and containers
CA3103274A1 (en) 2018-06-14 2019-12-19 Anton SABIEV Wireless iontophoresis patch and controller
US12324792B2 (en) 2020-12-28 2025-06-10 Smith & Nephew, Inc. Methods for making and using pharmaceutical compositions for iontophoresis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA981182A (en) * 1972-01-07 1976-01-06 Walter A. Borisenok Stabilization of 1-epinephrine in local anesthetic solutions with a combination of three antioxidants
AU615188B2 (en) * 1987-05-28 1991-09-26 Drug Delivery Systems Inc. Pulsating transdermal drug delivery system
JPS6411565A (en) * 1987-07-03 1989-01-17 Nitto Denko Corp Drug admistrating method by iontophoresis
US5261903A (en) * 1988-04-11 1993-11-16 M.D. Inc. Composite anesthetic article and method of use
US5047007A (en) * 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
MX9206990A (es) * 1991-12-03 1993-06-01 Alza Corp Dispositivo iontoforetico de surtido y suministro de energia para el mismo.
US5540669A (en) * 1993-09-30 1996-07-30 Becton, Dickinson And Company Iontophoretic drug delivery system and method for using same
US5563153A (en) * 1995-02-22 1996-10-08 University Of Kansas Medical Center Sterile topical anesthetic gel

Also Published As

Publication number Publication date
ATE238046T1 (de) 2003-05-15
WO1998020869A3 (en) 1998-07-23
AU721114B2 (en) 2000-06-22
DK0941085T3 (da) 2003-08-11
CA2271944A1 (en) 1998-05-22
KR20000053270A (ko) 2000-08-25
CN1237907A (zh) 1999-12-08
DE69721293D1 (de) 2003-05-28
JP2001505197A (ja) 2001-04-17
WO1998020869A2 (en) 1998-05-22
AU5166398A (en) 1998-06-03
PT941085E (pt) 2003-08-29
CN1155372C (zh) 2004-06-30
DE69721293T2 (de) 2004-01-29
KR100534512B1 (ko) 2005-12-08
EP0941085A2 (en) 1999-09-15
CA2271944C (en) 2008-04-29
EP0941085B1 (en) 2003-04-23

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