ES2195016T3 - Medicamento contra la trombocitopenia. - Google Patents

Medicamento contra la trombocitopenia.

Info

Publication number
ES2195016T3
ES2195016T3 ES96935352T ES96935352T ES2195016T3 ES 2195016 T3 ES2195016 T3 ES 2195016T3 ES 96935352 T ES96935352 T ES 96935352T ES 96935352 T ES96935352 T ES 96935352T ES 2195016 T3 ES2195016 T3 ES 2195016T3
Authority
ES
Spain
Prior art keywords
group
chr1r2
chr3r4
chr5r6
2chr3r4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96935352T
Other languages
English (en)
Inventor
Masayuki Saitoh
Yasuo Kitajima
Norio Iwasawa
Kenju Miura
Munetada Haruyama
Junko Hashino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asubio Pharma Co Ltd
Original Assignee
Daiichi Suntory Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Suntory Pharma Co Ltd filed Critical Daiichi Suntory Pharma Co Ltd
Application granted granted Critical
Publication of ES2195016T3 publication Critical patent/ES2195016T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPUESTOS REPRESENTADOS POR LA FORMULA GENERAL (I) O LAS SALES DE LOS MISMOS FARMACEUTICAMENTE ACEPTABLES: (DONDE R ES UN GRUPO - NHCHR{SUB,1}R{SUB,2}, N(CHR{SUB,1}R{SUB,2}){SUB,2}, N(CHR{SUB,1}R{SUB,2})CHR{SUB,3}R{SUB,4}, N{SUP,+}(CHR{SUB,1}R{SUB,2}){SUB,3}, N{SUP,+}(CHR{SUB,1}R{SUB,2}){SUB,2}CHR{SUB,3}R{SUB,4} O N{SUP,+}(CHR{SUB,1}R{SUB,2})(CHR{SUB,3}R{SUB,4})CHR{SUB,5}R{SU B,6} (DONDE R{SUB,1}, R{SUB,2}, R{SUB,3}, R{SUB,4}, R{SUB,5} Y R{SUB,6}, QUE PUEDEN SER IGUALES O DIFERENTES, SON UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO, UN GRUPO ALQUENILO, UN GRUPO ARILO O UN GRUPO ARALQUILO, O UN GRUPO ALQUILO, ALQUENILO, ARILO O ARALQUILO QUE ESTA SUSTITUIDO POR AL MENOS UN SUSTITUYENTE SELECCIONADO DE UN GRUPO COMPRENDIDO POR UN ATOMO DE HALOGENO, UN GRUPO HIDROXILO, UN GRUPO ALCOXI DE CADENA CORTA, UN GRUPO ALQUIACILOXI DE CADENA CORTA, UN GRUPO ALQUILACILO DE CADENA CORTA, UN GRUPO ALCOXICARBONILO DE CADENA CORTA, UN GRUPO NITRO, UN GRUPO CIANO Y UN GRUPO HETEROCICLICO, FORMANDO OPCIONALMENTEUN ALQUILO CICLICO CON CHR{SUB,1}R{SUB,2}CHR{SUB,3}R{SUB,4}, O CHR{SUB,5}R{SUB,6}, SIEMPRE QUE CUANDO R SEA N(CHR{SUB,1}R{SUB,2}CHR{SUB,3}R{SUB,4}, N{SUP,+}(CHR{SUB,1}R{SUB,2}){SUB,2}CHR{SUB,3}R{SUB,4} O N{SUP,+}(CHR{SUB,1}R{SUB,2})(CHR{SUB,3}R{SUB,4})CHR{SUB,5}R{SU B,6}, CHR{SUB,1}R{SUB,2}, CHR{SUB,3}R{SUB,4} Y CHR{SUB,5}R{SUB,6} SEAN GRUPOS DIFERENTES); LOS AGENTES TERAPEUTICOS PARA LA TROMBOCITOPENIA CONTIENEN ESTOS COMPUESTOS COMO PRINCIPIO ACTIVO EFICAZ; ASI COMO LOS INTERMEDIOS DE SU SINTESIS Y LOS PROCESOS PARA SU PRODUCCION.
ES96935352T 1995-10-17 1996-10-17 Medicamento contra la trombocitopenia. Expired - Lifetime ES2195016T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP26864495 1995-10-17

Publications (1)

Publication Number Publication Date
ES2195016T3 true ES2195016T3 (es) 2003-12-01

Family

ID=17461419

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96935352T Expired - Lifetime ES2195016T3 (es) 1995-10-17 1996-10-17 Medicamento contra la trombocitopenia.

Country Status (9)

Country Link
US (1) US6040335A (es)
EP (1) EP0798304B1 (es)
KR (1) KR980700316A (es)
AT (1) ATE234315T1 (es)
AU (1) AU702751B2 (es)
CA (1) CA2207656A1 (es)
DE (1) DE69626624T2 (es)
ES (1) ES2195016T3 (es)
WO (1) WO1997014704A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1466912E (pt) * 2002-01-18 2013-06-28 Astellas Pharma Inc Derivado de 2-aciloaminotiazol ou seu sal
US7851503B2 (en) 2002-08-14 2010-12-14 Nissan Chemical Industries, Ltd. Thrombopoetin receptor activator and process for producing the same
WO2007054783A2 (en) * 2005-11-08 2007-05-18 Astellas Pharma Inc. Compositions and methods for treating thrombocytopenia
ES2452032T3 (es) * 2006-08-08 2014-03-31 Akarx, Inc. Composiciones y métodos para aumentar los niveles de plaquetas de la sangre en humanos

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235913A (en) * 1977-06-07 1980-11-25 Pfizer Inc. 9-Hydroxyhexahydrodibeno[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo]b,d]pyrans
US4725602A (en) * 1984-02-06 1988-02-16 Mcneilab, Inc. Acetylene amines and their use as vasodilators and antihypertensives
JPH02186A (ja) * 1987-05-07 1990-01-05 Sumitomo Chem Co Ltd 新規化合物およびそれを有効成分とする農工業用殺菌剤
JP2865302B2 (ja) * 1988-02-13 1999-03-08 サントリー株式会社 ２―ピラノン誘導体及びその製造法並びにそれを含む抗菌剤
AU649116B2 (en) * 1991-03-27 1994-05-12 Sankyo Company Limited New compounds, named the "Leustroducins", their preparation and their therapeutic uses
JP3034646B2 (ja) * 1991-06-20 2000-04-17 三共株式会社 Ｇ−ｃｓｆおよびｇｍ−ｃｓｆ誘導剤
JPH05213758A (ja) * 1992-02-06 1993-08-24 Sankyo Co Ltd 血小板増多剤
JPH05221867A (ja) * 1992-02-17 1993-08-31 Sankyo Co Ltd Ｉｌ−６誘導剤
DK0622372T3 (da) * 1993-04-23 1999-02-15 Sankyo Co Hidtil ukendt forbindelse, Leustroducsin H, dens fremstilling og dens terapeutiske anvendelse
JPH0841087A (ja) * 1994-08-03 1996-02-13 Sankyo Co Ltd Ｎ−アシルロイストロダクシン類

Also Published As

Publication number Publication date
EP0798304B1 (en) 2003-03-12
AU7332996A (en) 1997-05-07
DE69626624D1 (de) 2003-04-17
ATE234315T1 (de) 2003-03-15
US6040335A (en) 2000-03-21
EP0798304A1 (en) 1997-10-01
AU702751B2 (en) 1999-03-04
EP0798304A4 (en) 1999-02-10
WO1997014704A1 (fr) 1997-04-24
CA2207656A1 (en) 1997-04-24
DE69626624T2 (de) 2003-11-27
KR980700316A (ko) 1998-03-30

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