ES2195053T3 - Composicion de reactivos que contiene particulas magneticas en forma de una tableta. - Google Patents

Composicion de reactivos que contiene particulas magneticas en forma de una tableta.

Info

Publication number
ES2195053T3
ES2195053T3 ES97109177T ES97109177T ES2195053T3 ES 2195053 T3 ES2195053 T3 ES 2195053T3 ES 97109177 T ES97109177 T ES 97109177T ES 97109177 T ES97109177 T ES 97109177T ES 2195053 T3 ES2195053 T3 ES 2195053T3
Authority
ES
Spain
Prior art keywords
magnetic particles
tablet
sample
composition
containing magnetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97109177T
Other languages
English (en)
Inventor
Herbert Dr Harttig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Application granted granted Critical
Publication of ES2195053T3 publication Critical patent/ES2195053T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

EL OBJETO DE LA INVENCION ES UNA PREPARACION REACTIVA PARA LIGAR LAS SUSTANCIAS DE CONTENIDO DE UNA MUESTRA, EN FORMA DE UNA TABLETA QUE CONTIENE UNA GRAN CANTIDAD DE PARTICULAS MAGNETICAS QUE SE MANTIENEN UNIDAS GRACIAS A UNOS MEDIOS AUXILIARES PARA HACER TABLETAS. LA INVENCION SE REFIERE TAMBIEN AL USO DE ESTA PREPARACION REACTIVA EN PRUEBAS ANALITICAS.
ES97109177T 1996-06-07 1997-06-06 Composicion de reactivos que contiene particulas magneticas en forma de una tableta. Expired - Lifetime ES2195053T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19622885A DE19622885A1 (de) 1996-06-07 1996-06-07 Reagenzzubereitung enthaltend magnetische Partikel in Form einer Tablette

Publications (1)

Publication Number Publication Date
ES2195053T3 true ES2195053T3 (es) 2003-12-01

Family

ID=7796390

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97109177T Expired - Lifetime ES2195053T3 (es) 1996-06-07 1997-06-06 Composicion de reactivos que contiene particulas magneticas en forma de una tableta.

Country Status (11)

Country Link
US (2) US6274386B1 (es)
EP (1) EP0811694B1 (es)
JP (1) JP3821541B2 (es)
KR (1) KR100260326B1 (es)
AT (1) ATE234366T1 (es)
AU (1) AU715803B2 (es)
CA (1) CA2206760C (es)
DE (2) DE19622885A1 (es)
DK (1) DK0811694T3 (es)
ES (1) ES2195053T3 (es)
IL (1) IL121008A (es)

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DE19520398B4 (de) * 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
WO2000032762A1 (de) 1998-11-30 2000-06-08 Roche Diagnostics Gmbh Magnetische partikel zur reinigung von nukleinsäuren
KR100463475B1 (ko) 1995-06-08 2005-06-22 로셰 디아그노스틱스 게엠베하 자기성피그먼트
DE19743518A1 (de) * 1997-10-01 1999-04-15 Roche Diagnostics Gmbh Automatisierbare universell anwendbare Probenvorbereitungsmethode
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
DE69940647D1 (de) 1998-05-01 2009-05-07 Gen Probe Inc Automatische diagnostische Analysevorrichtung
US8337753B2 (en) * 1998-05-01 2012-12-25 Gen-Probe Incorporated Temperature-controlled incubator having a receptacle mixing mechanism
DE19836559A1 (de) 1998-08-12 2000-03-23 Antigen Gmbh Gefäß zur Entnahme von Blut
CA2392009C (en) * 1999-11-17 2009-07-14 Roche Diagnostics Gmbh Magnetic glass particles, method for their preparation and uses thereof
AU778713B2 (en) * 2000-02-04 2004-12-16 Qiagen Gmbh Nucleic acid isolation from stool samples and other inhibitor-rich biological materials
DE10006662A1 (de) * 2000-02-15 2001-08-23 Antigen Produktions Gmbh Gefäß zur Nukleinsäureanalytik
JP2003527372A (ja) * 2000-03-17 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット ポリマー支持担体の投与形態、前記投与形態を有機化学合成に使用する方法及び前記投与形態を製造する方法
JP2003527373A (ja) * 2000-03-17 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット 試薬用剤形、有機化学合成における上記剤形の使用および上記剤形の製造
US6602718B1 (en) 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
CA2759764C (en) * 2002-02-14 2017-06-13 Veridex, Llc Methods and algorithms for cell enumeration in a low-cost cytometer
US9267167B2 (en) * 2004-06-28 2016-02-23 Becton, Dickinson And Company Dissolvable films and methods including the same
CA2570802A1 (en) * 2004-06-28 2006-01-05 H. Lundbeck A/S Porous article for delivering chemical substances
US8189899B2 (en) * 2004-07-30 2012-05-29 Veridex, Llc Methods and algorithms for cell enumeration in a low-cost cytometer
KR100850430B1 (ko) * 2006-12-11 2008-08-05 (주)바이오니아 입자상 물질을 사용하는 핵산 분리 방법 및 핵산 분리용조성물
EP2143496A1 (en) * 2008-07-09 2010-01-13 F. Hoffmann-Roche AG Lysis reagent formulation containing magnetic particles in tablet form
CA2772020A1 (en) * 2009-08-31 2011-03-03 Mbio Diagnostics, Inc. Integrated sample preparation and analyte detection
TWI407994B (zh) 2009-10-22 2013-09-11 Ind Tech Res Inst 分離核酸的方法、試劑及套組
EP4269582A3 (en) 2017-12-21 2024-01-24 F. Hoffmann-La Roche AG Target enrichment by unidirectional dual probe primer extension
CN111801427B (zh) 2018-02-05 2023-12-05 豪夫迈·罗氏有限公司 用于单分子的单链环状dna模板的产生
WO2019166565A1 (en) 2018-03-02 2019-09-06 F. Hoffmann-La Roche Ag Generation of double-stranded dna templates for single molecule sequencing
JP7152599B2 (ja) 2018-09-21 2022-10-12 エフ．ホフマン－ラ ロシュ アーゲー 塩基配列決定のためのモジュール式およびコンビナトリアル核酸試料調製のためのシステムおよび方法
EP4031679A1 (en) 2019-09-20 2022-07-27 F. Hoffmann-La Roche AG Immune repertoire profiling by primer extension target enrichment
CN115956128B (zh) 2020-07-08 2026-03-27 豪夫迈·罗氏有限公司 在下一代测序文库的靶捕获过程中使用毒性引物对非靶文库分子进行靶向消耗
US12378596B2 (en) 2020-12-03 2025-08-05 Roche Sequencing Solutions, Inc. Whole transcriptome analysis in single cells
WO2024013241A1 (en) 2022-07-14 2024-01-18 F. Hoffmann-La Roche Ag Variant allele enrichment by unidirectional dual probe primer extension
CN122374014A (zh) 2023-12-11 2026-07-10 库贝生物科技有限公司 包含功能化琼脂糖颗粒的片剂、其生产方法以及该片剂的用途
WO2025240460A2 (en) 2024-05-14 2025-11-20 Roche Molecular Systems, Inc. Assay for detection of mutations conferring resistance to treatment with an immunotherapeutic agent

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US3981776A (en) * 1967-02-16 1976-09-21 Rolf Saxholm Magnetically responsive, biologically active substance and associated methods and apparatus
US4115534A (en) * 1976-08-19 1978-09-19 Minnesota Mining And Manufacturing Company In vitro diagnostic test
US4169804A (en) * 1976-08-19 1979-10-02 Minnesota Mining And Manufacturing Company Magnetically responsive composite microparticle
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US4343901A (en) 1980-10-22 1982-08-10 Uop Inc. Magnetic support matrix for enzyme immobilization
US4483920A (en) * 1982-05-17 1984-11-20 Hahnemann University Immobilization of message RNA directly from cells onto filter material
US4735796A (en) * 1983-12-08 1988-04-05 Gordon Robert T Ferromagnetic, diamagnetic or paramagnetic particles useful in the diagnosis and treatment of disease
US5746999A (en) * 1984-11-23 1998-05-05 Schering Aktiengesellschaft Magnetic particles for diagnostic purposes
US5597531A (en) * 1985-10-04 1997-01-28 Immunivest Corporation Resuspendable coated magnetic particles and stable magnetic particle suspensions
US5009994A (en) * 1986-03-24 1991-04-23 Em Diagnostic Systems, Inc. Particles containing mannitol suitable for tabletting into diagnostic reagents
US4820627A (en) * 1986-03-24 1989-04-11 Em Diagnostic Systems, Inc. Method of preparing particles suitable for tabletting into diagnostic reagents
US4712310A (en) * 1986-09-15 1987-12-15 E. I. Du Pont De Nemours And Company Co-spray technique
NO892244L (no) * 1988-06-06 1989-12-07 Photest Diagnostics Inc Fremgangsmaate til immundiagnostisk bestemmelse.
US5512439A (en) * 1988-11-21 1996-04-30 Dynal As Oligonucleotide-linked magnetic particles and uses thereof
CA2003508C (en) * 1988-11-21 2000-01-25 Erik Hornes Monodisperse superparamagnetic particles for use in nucleic acid analyses
US5234809A (en) * 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
JPH04323560A (ja) * 1991-04-22 1992-11-12 Nippon Telegr & Teleph Corp <Ntt> レーザ磁気免疫測定に用いられる磁性微粒子標識材料並びに検体調整方法
DE4406139A1 (de) * 1994-02-25 1995-08-31 Matthias Werner Magnetische Depotarzneimittel für die perorale Applikation mit verbesserter Resorption der Wirkstoffe
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DE19520398B4 (de) * 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment

Also Published As

Publication number Publication date
IL121008A (en) 2001-08-08
JPH1062422A (ja) 1998-03-06
ATE234366T1 (de) 2003-03-15
DE59709467D1 (de) 2003-04-17
CA2206760A1 (en) 1997-12-07
KR980003584A (ko) 1998-03-30
EP0811694A3 (de) 1999-01-13
IL121008A0 (en) 1997-11-20
AU2370597A (en) 1997-12-11
EP0811694B1 (de) 2003-03-12
CA2206760C (en) 2003-08-19
JP3821541B2 (ja) 2006-09-13
AU715803B2 (en) 2000-02-10
US20010046714A1 (en) 2001-11-29
US6746874B2 (en) 2004-06-08
EP0811694A2 (de) 1997-12-10
DK0811694T3 (da) 2003-07-14
KR100260326B1 (ko) 2003-03-15
US6274386B1 (en) 2001-08-14
DE19622885A1 (de) 1997-12-11

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