ES2215236T3 - Tratamiento con substancia p para inmunoestimulacion. - Google Patents
Tratamiento con substancia p para inmunoestimulacion.Info
- Publication number
- ES2215236T3 ES2215236T3 ES97938049T ES97938049T ES2215236T3 ES 2215236 T3 ES2215236 T3 ES 2215236T3 ES 97938049 T ES97938049 T ES 97938049T ES 97938049 T ES97938049 T ES 97938049T ES 2215236 T3 ES2215236 T3 ES 2215236T3
- Authority
- ES
- Spain
- Prior art keywords
- substance
- treatment
- immune
- aerosols
- useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000011282 treatment Methods 0.000 title abstract 3
- 230000003308 immunostimulating effect Effects 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- 210000000987 immune system Anatomy 0.000 abstract 3
- QDZOEBFLNHCSSF-PFFBOGFISA-N (2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2R)-2-amino-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide Chemical compound C([C@@H](C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](N)CCCNC(N)=N)C1=CC=CC=C1 QDZOEBFLNHCSSF-PFFBOGFISA-N 0.000 abstract 2
- 102100024304 Protachykinin-1 Human genes 0.000 abstract 2
- 101800003906 Substance P Proteins 0.000 abstract 2
- 239000000443 aerosol Substances 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 230000001010 compromised effect Effects 0.000 abstract 1
- 231100001238 environmental toxicant Toxicity 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002430 hydrocarbons Chemical class 0.000 abstract 1
- 230000036737 immune function Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000035800 maturation Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
ESTA INVENCION SE REFIERE A UNOS AEROSOLES DE SUSTANCIA P QUE SON EFICACES PARA RECONSTITUIR LOS SISTEMAS INMUNITARIOS COMPROMETIDOS POR SUSTANCIAS TOXICAS DEL MEDIOAMBIENTE. SON TAMBIEN UTILES PARA LA PROFILAXIS DE LAS INFECCIONES Y NEOPLASMAS, ASI COMO SU TRATAMIENTO. SON ADEMAS UTILES PARA ACELERAR LA MADURACION DE SISTEMAS INMUNITARIOS O TAMBIEN MANTENER LA FUNCION INMUNITARIA. LA EXPOSICION CRONICA A LOS HIDROCARBUROS ES ESPECIALMENTE PELIGROSA PARA EL SISTEMA INMUNITARIO, Y POR LO TANTO, SE PUEDE CONTRARRESTAR ESTE RIESGO PROFESIONAL MEDIANTE UN TRATAMIENTO CON AEROSOLES DE SUSTANCIA P.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2206396P | 1996-07-23 | 1996-07-23 | |
| US08/829,445 US5945508A (en) | 1996-07-23 | 1997-03-28 | Substance P treatment for immunostimulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2215236T3 true ES2215236T3 (es) | 2004-10-01 |
Family
ID=26695449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES97938049T Expired - Lifetime ES2215236T3 (es) | 1996-07-23 | 1997-07-08 | Tratamiento con substancia p para inmunoestimulacion. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5945508A (es) |
| EP (1) | EP0957930B1 (es) |
| AT (1) | ATE262342T1 (es) |
| AU (1) | AU737201B2 (es) |
| CA (1) | CA2261885A1 (es) |
| DE (1) | DE69728294T2 (es) |
| ES (1) | ES2215236T3 (es) |
| WO (1) | WO1998003194A2 (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6573244B1 (en) * | 1999-05-17 | 2003-06-03 | The United States Of America As Represented By The Secretary Of The Army | Previns as specific inhibitors and therapeutic agents for Botulinum toxin B and Tetanus neurotoxins |
| DE60139874D1 (de) * | 2000-07-28 | 2009-10-22 | Christopher J Murphy | Medium für transplantat |
| IT1317895B1 (it) * | 2000-08-10 | 2003-07-15 | Univ Napoli Federico Ii | Pseudo-metalloproteine, loro preparazione e loro uso. |
| WO2002102835A2 (en) * | 2000-11-21 | 2002-12-27 | New England Medical Center | Novel antimicrobial compounds |
| US6437093B1 (en) * | 2000-11-28 | 2002-08-20 | Milkhaus Laboratory, Inc. | Methods of treatment comprising administration of Substance P |
| CA2496447A1 (en) * | 2002-08-27 | 2004-03-11 | Mark L. Witten | Amelioration of effects of cigarette smoke |
| AU2003293582A1 (en) * | 2002-12-18 | 2004-07-22 | Mark L. Witten | Stimulation of hair regrowth |
| WO2004091649A1 (en) * | 2003-04-14 | 2004-10-28 | Immuneregen Biosciences, Inc. | Acute respiratory syndromes |
| US20070207209A1 (en) * | 2004-08-27 | 2007-09-06 | Murphy Christopher J | Trophic factor combinations for nervous system treatment |
| CA2580694A1 (en) * | 2004-09-23 | 2006-03-30 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| EP1809313A4 (en) * | 2004-10-27 | 2008-01-23 | Immuneregen Biosciences Inc | PROCESS FOR PROMOTING WOUND HEALING |
| KR100593397B1 (ko) * | 2004-10-27 | 2006-06-28 | 한국원자력연구소 | 중배엽 줄기세포 및/또는 p 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제 |
| SG123646A1 (en) * | 2005-01-05 | 2006-07-26 | Immuneregen Biosciences Inc | Prevention of respiratory infections in fowl |
| CA2594517A1 (en) * | 2005-01-12 | 2006-07-20 | Immuneregen Biosciences, Inc. | Treatment of skin diseases |
| SG126014A1 (en) * | 2005-04-01 | 2006-10-30 | Immuneregen Biosciences Inc | Treatment of asthma |
| US20060281670A1 (en) * | 2005-06-10 | 2006-12-14 | Wisconsin Alumni Research Foundation (Warf) | Compositions and methods for modulating angiogenesis |
| WO2007062060A2 (en) | 2005-11-22 | 2007-05-31 | Ted Reid | Methods and compositions using substance p to promote wound healing |
| US20090137492A1 (en) * | 2006-03-10 | 2009-05-28 | Immuneregen Biosciences, Inc. | Method to reduce the risk and/or severity of anthrax infection |
| WO2008036157A2 (en) * | 2006-08-15 | 2008-03-27 | Immuneregen Biosciences, Inc. | Prophylactic and therapeutic treatment of avian influenza infections in animals |
| WO2008088846A2 (en) * | 2007-01-18 | 2008-07-24 | Immuneregen Biosciences, Inc. | Substance p and analogs thereof as an immunogenic composition adjuvant |
| US8321012B2 (en) | 2009-12-22 | 2012-11-27 | The Invention Science Fund I, Llc | Device, method, and system for neural modulation as vaccine adjuvant in a vertebrate subject |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5410019A (en) * | 1987-09-24 | 1995-04-25 | The Administrators Of The Tulane-Educational Fund | Therapeutic peptides |
| US5256765A (en) * | 1989-03-09 | 1993-10-26 | The Johns Hopkins University School Of Medicine | Biodegradable poly(phosphate esters) |
| JPH06510752A (ja) * | 1991-05-24 | 1994-12-01 | ノースウエスタン・ユニバーシティ | アレルギー治療のためのp物質の使用方法 |
| EP0545478A1 (en) * | 1991-12-03 | 1993-06-09 | MERCK SHARP & DOHME LTD. | Heterocyclic compounds as tachykinin antagonists |
| ATE206710T1 (de) * | 1994-06-06 | 2001-10-15 | Warner Lambert Co | Tachykinin (nk1) rezeptor antagonisten |
-
1997
- 1997-03-28 US US08/829,445 patent/US5945508A/en not_active Expired - Lifetime
- 1997-07-08 AU AU40464/97A patent/AU737201B2/en not_active Ceased
- 1997-07-08 DE DE69728294T patent/DE69728294T2/de not_active Expired - Fee Related
- 1997-07-08 CA CA002261885A patent/CA2261885A1/en not_active Abandoned
- 1997-07-08 WO PCT/US1997/013146 patent/WO1998003194A2/en not_active Ceased
- 1997-07-08 EP EP97938049A patent/EP0957930B1/en not_active Expired - Lifetime
- 1997-07-08 AT AT97938049T patent/ATE262342T1/de not_active IP Right Cessation
- 1997-07-08 ES ES97938049T patent/ES2215236T3/es not_active Expired - Lifetime
-
1998
- 1998-02-23 US US09/028,003 patent/US5998376A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5945508A (en) | 1999-08-31 |
| ATE262342T1 (de) | 2004-04-15 |
| US5998376A (en) | 1999-12-07 |
| EP0957930B1 (en) | 2004-03-24 |
| WO1998003194A3 (en) | 1998-06-18 |
| WO1998003194A2 (en) | 1998-01-29 |
| CA2261885A1 (en) | 1998-01-29 |
| DE69728294T2 (de) | 2004-08-19 |
| EP0957930A2 (en) | 1999-11-24 |
| AU737201B2 (en) | 2001-08-09 |
| AU4046497A (en) | 1998-02-10 |
| DE69728294D1 (de) | 2004-04-29 |
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