ES2219028T3 - Uso de bisfosfonatos para el tratamiento de restenosis vascular. - Google Patents

Uso de bisfosfonatos para el tratamiento de restenosis vascular.

Info

Publication number
ES2219028T3
ES2219028T3 ES99929687T ES99929687T ES2219028T3 ES 2219028 T3 ES2219028 T3 ES 2219028T3 ES 99929687 T ES99929687 T ES 99929687T ES 99929687 T ES99929687 T ES 99929687T ES 2219028 T3 ES2219028 T3 ES 2219028T3
Authority
ES
Spain
Prior art keywords
treatment
bisphosphonates
vascular restenosis
restenosis
vascular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99929687T
Other languages
English (en)
Inventor
Gershon Golomb
Haim Daneberg
Dr Jukka Minkkinen
Dr Ilia Fishbein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hadasit Medical Research Services and Development Co
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Hadasit Medical Research Services and Development Co
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadasit Medical Research Services and Development Co, Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Hadasit Medical Research Services and Development Co
Application granted granted Critical
Publication of ES2219028T3 publication Critical patent/ES2219028T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)

Abstract

Uso de un ingrediente activo que es bisfosfonato (BP) en partículas, o un complejo en partículas o una sal de BP, o polímero en partículas de BP, que está en una forma de partículas micronizadas que tienen un diámetro en el intervalo de 0, 01- 10 my-m, para la preparación de una composición farmacéutica destinada a la prevención o tratamiento de restenosis vascular.
ES99929687T 1998-07-14 1999-07-14 Uso de bisfosfonatos para el tratamiento de restenosis vascular. Expired - Lifetime ES2219028T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL12533698A IL125336A0 (en) 1998-07-14 1998-07-14 Compositions for inhibition and treatment of restinosis

Publications (1)

Publication Number Publication Date
ES2219028T3 true ES2219028T3 (es) 2004-11-16

Family

ID=11071743

Family Applications (2)

Application Number Title Priority Date Filing Date
ES99929687T Expired - Lifetime ES2219028T3 (es) 1998-07-14 1999-07-14 Uso de bisfosfonatos para el tratamiento de restenosis vascular.
ES04006854T Expired - Lifetime ES2347553T3 (es) 1998-07-14 1999-07-14 Uso de bisfosfonatos en el tratamiento de la reestenosis vascular.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES04006854T Expired - Lifetime ES2347553T3 (es) 1998-07-14 1999-07-14 Uso de bisfosfonatos en el tratamiento de la reestenosis vascular.

Country Status (17)

Country Link
US (1) US6719998B1 (es)
EP (2) EP1094820B1 (es)
JP (4) JP4663116B2 (es)
KR (1) KR20010074711A (es)
CN (1) CN1321090A (es)
AT (2) ATE471149T1 (es)
AU (1) AU758882B2 (es)
BR (1) BR9912066A (es)
CA (1) CA2337175C (es)
DE (2) DE69942510D1 (es)
EE (1) EE200100025A (es)
ES (2) ES2219028T3 (es)
IL (3) IL125336A0 (es)
NO (1) NO20010224L (es)
PL (1) PL345782A1 (es)
SK (1) SK472001A3 (es)
WO (1) WO2000003677A2 (es)

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KR100994543B1 (ko) * 2001-02-16 2010-11-16 아스텔라스세이야쿠 가부시키가이샤 Ｆｋ506을 포함하는 이식편
US6656506B1 (en) * 2001-05-09 2003-12-02 Advanced Cardiovascular Systems, Inc. Microparticle coated medical device
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US8034361B2 (en) * 2002-11-12 2011-10-11 Advanced Cardiovascular Systems, Inc. Stent coatings incorporating nanoparticles
US10517883B2 (en) * 2003-06-27 2019-12-31 Zuli Holdings Ltd. Method of treating acute myocardial infarction
AU2004253527B2 (en) * 2003-06-27 2010-04-08 Zuli Holdings Ltd. Method of treating acute coronary syndromes
US20060051407A1 (en) * 2003-06-27 2006-03-09 Yoram Richter Method of treating ischemia-reperfusion injury
US20050153937A1 (en) * 2003-11-07 2005-07-14 Gershon Golomb Desensitization of compliment activation using monocyte/macrophage inhibitory compounds
CN100364544C (zh) * 2004-07-21 2008-01-30 上海第二医科大学附属瑞金医院 一种携带二氯亚甲基二膦酸的明胶微粒及制备方法
EP1802641B8 (en) 2004-10-08 2012-03-07 The Board Of Trustees Of The University Of Illinois Bisphosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases
US7687482B2 (en) 2006-03-17 2010-03-30 The Board Of Trustees Of The University Of Illinois Bisphosphonate compounds and methods
US8012949B2 (en) 2004-10-08 2011-09-06 The Board Of Trustees Of The University Of Illinois Bisphosphonate compounds and methods with enhanced potency for multiple targets including FPPS, GGPPS, and DPPS
EP2316441A1 (en) 2005-02-17 2011-05-04 Hadasit Medical Research Services And Development Bisphosphonates for treating endometriosis
CN101198316A (zh) * 2005-03-17 2008-06-11 伊兰制药国际有限公司 纳米微粒双膦酸盐组合物
US20080181928A1 (en) * 2006-12-22 2008-07-31 Miv Therapeutics, Inc. Coatings for implantable medical devices for liposome delivery
US8802184B2 (en) 2007-05-30 2014-08-12 Abbott Cardiovascular Systems Inc. Medical devices containing biobeneficial particles
JP2011500150A (ja) * 2007-10-10 2011-01-06 エムアイヴィ テラピューティクス， インコーポレイテッド インプラント用医療デバイスのための脂質コーティング
US20090148491A1 (en) * 2007-12-05 2009-06-11 Abbott Cardiovascular Systems Inc. Dual-Targeted Drug Carriers
US20090215729A1 (en) * 2008-02-19 2009-08-27 Johnson Erin M Microparticle compositions to modify cancer promoting cells
EP2313101A4 (en) * 2008-07-09 2014-05-21 Univ Nebraska FUNCTIONAL MICELLES FOR HARD FIBER-RELATED CHEMICAL RELEASE RELEASE
US20130315981A1 (en) * 2010-06-25 2013-11-28 The Trustees Of Columbia University In The City Of New York Method for inducing fat loss in mammals
GB201200868D0 (en) * 2012-01-19 2012-02-29 Depuy Int Ltd Bone filler composition
EP2769741A1 (en) * 2013-02-22 2014-08-27 Cardiatis S.A. Medical device with a biocompatible coating
US9993427B2 (en) 2013-03-14 2018-06-12 Biorest Ltd. Liposome formulation and manufacture
CN106456775A (zh) 2014-05-16 2017-02-22 生物休眠有限公司 双膦酸盐作为hiv/aids辅助治疗的用途
EP3492166A4 (en) * 2016-08-01 2020-03-11 Kaneka Corporation ADSORBENT FOR CALCIPROTEIN PARTICLES, ADSORPTION REMOVAL SYSTEM AND METHOD OF USE
CN106361701B (zh) * 2016-08-31 2019-08-27 上海交通大学 一种脂质体药物载体及其制备方法和应用
FR3068233A1 (fr) * 2017-07-03 2019-01-04 Omnium De Revalorisation Industrielle Odri Dispositif medical intra-arteriel et applications
JP6613290B2 (ja) 2017-11-28 2019-11-27 株式会社Ｓｕｂａｒｕ 運転アドバイス装置及び運転アドバイス方法

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PH27186A (en) 1989-09-07 1993-04-16 Ciba Geigy Ag Double-coated granules of disodium pamidronate
CA2042159A1 (en) 1990-05-31 1991-12-01 Miguel A. Ondetti Method for preventing onset of restenosis after angioplasty employing an ace inhibitor
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Also Published As

Publication number Publication date
JP4663116B2 (ja) 2011-03-30
EP1468691A1 (en) 2004-10-20
EE200100025A (et) 2002-06-17
JP5498342B2 (ja) 2014-05-21
NO20010224L (no) 2001-03-09
DE69915834D1 (de) 2004-04-29
JP6088619B2 (ja) 2017-03-01
DE69942510D1 (de) 2010-07-29
ES2347553T3 (es) 2010-11-02
BR9912066A (pt) 2001-04-10
WO2000003677A2 (en) 2000-01-27
JP2011037871A (ja) 2011-02-24
ATE471149T1 (de) 2010-07-15
JP5903081B2 (ja) 2016-04-13
NO20010224D0 (no) 2001-01-12
US6719998B1 (en) 2004-04-13
WO2000003677A3 (en) 2000-05-04
CA2337175A1 (en) 2000-01-27
JP2013256524A (ja) 2013-12-26
AU758882B2 (en) 2003-04-03
ATE262338T1 (de) 2004-04-15
CN1321090A (zh) 2001-11-07
AU4646299A (en) 2000-02-07
JP2002520345A (ja) 2002-07-09
EP1094820A2 (en) 2001-05-02
JP2016041724A (ja) 2016-03-31
KR20010074711A (ko) 2001-08-09
SK472001A3 (en) 2001-09-11
EP1094820B1 (en) 2004-03-24
DE69915834T2 (de) 2005-03-24
EP1468691B1 (en) 2010-06-16
CA2337175C (en) 2009-03-31
PL345782A1 (en) 2002-01-02
IL142172A0 (en) 2002-03-10
IL142172A (en) 2007-07-24
IL125336A0 (en) 1999-03-12

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