ES2221957T5 - Método para la eliminación cromatográfica de priones. - Google Patents

Método para la eliminación cromatográfica de priones. Download PDF

Info

Publication number
ES2221957T5
ES2221957T5 ES97932311T ES97932311T ES2221957T5 ES 2221957 T5 ES2221957 T5 ES 2221957T5 ES 97932311 T ES97932311 T ES 97932311T ES 97932311 T ES97932311 T ES 97932311T ES 2221957 T5 ES2221957 T5 ES 2221957T5
Authority
ES
Spain
Prior art keywords
hemoglobin
prion
solution
gradient
bovine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97932311T
Other languages
English (en)
Spanish (es)
Other versions
ES2221957T3 (es
Inventor
Maria S. Gawryl
Robert A. Houtchens
William R. Light
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biopure Corp
OPK Biotech LLC
Original Assignee
Biopure Corp
OPK Biotech LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24701495&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2221957(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biopure Corp, OPK Biotech LLC filed Critical Biopure Corp
Publication of ES2221957T3 publication Critical patent/ES2221957T3/es
Application granted granted Critical
Publication of ES2221957T5 publication Critical patent/ES2221957T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • General Preparation And Processing Of Foods (AREA)
ES97932311T 1996-07-01 1997-06-26 Método para la eliminación cromatográfica de priones. Expired - Lifetime ES2221957T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/673,147 US5808011A (en) 1996-07-01 1996-07-01 Method for chromatographic removal of prions
US673147 1996-07-01

Publications (2)

Publication Number Publication Date
ES2221957T3 ES2221957T3 (es) 2005-01-16
ES2221957T5 true ES2221957T5 (es) 2012-01-27

Family

ID=24701495

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97932311T Expired - Lifetime ES2221957T5 (es) 1996-07-01 1997-06-26 Método para la eliminación cromatográfica de priones.

Country Status (12)

Country Link
US (1) US5808011A (2)
EP (1) EP0954528B2 (2)
JP (1) JP4031833B2 (2)
CN (2) CN1283660C (2)
AT (1) ATE267212T1 (2)
AU (1) AU718557B2 (2)
BR (1) BR9710035A (2)
CA (1) CA2259632C (2)
DE (1) DE69729217T3 (2)
ES (1) ES2221957T5 (2)
TW (1) TW390887B (2)
WO (1) WO1998000441A1 (2)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040053208A1 (en) * 1995-08-29 2004-03-18 V. I. TECHNOLOGIES, Inc. Methods to selectively inactivate parasites in biological compositions
US6221614B1 (en) 1997-02-21 2001-04-24 The Regents Of The University Of California Removal of prions from blood, plasma and other liquids
US20060008494A1 (en) * 1997-02-21 2006-01-12 The Regents Of The University Of California Complete inactivation of infectious proteins
US6620629B1 (en) 1997-02-21 2003-09-16 The Regents Of The University Of California Method for detecting prions
US6719988B2 (en) 1997-02-21 2004-04-13 The Regents Of The University Of California Antiseptic compositions for inactivating prions
US6720355B2 (en) 1997-02-21 2004-04-13 The Regents Of The University Of California Sodium dodecyl sulfate compositions for inactivating prions
US6617119B2 (en) 1997-02-21 2003-09-09 The Regents Of The University Of California Assay for specific strains of multiple disease related conformations of a protein
ES2193499T3 (es) * 1998-02-11 2003-11-01 Zlb Bioplasma Ag Un metodo para la eliminacion de un agente o agentes causantes de encefalopatias espongiformes transmisibles de soluciones proteinicas.
US6139878A (en) * 1998-04-27 2000-10-31 Aventis Behring, Llc Method for preparing a diafiltered stabilized blood product
US6150172A (en) * 1999-01-08 2000-11-21 The United States Of America As Represented By The Secretary Of Agriculture Method and kit for extracting prion protein
US6605445B1 (en) * 1999-02-22 2003-08-12 Bayer Corporation Rapid method of determining clearance of prion protein
US6166187A (en) 1999-03-05 2000-12-26 The Regents Of The University Of California Method of concentrating prion proteins in blood samples
US6437102B1 (en) * 1999-11-24 2002-08-20 Bayer Corporation Method of separating prions from biological materials
CA2405568A1 (en) * 2000-04-05 2001-10-18 North Carolina State University Prion-binding peptidic ligands and methods of using same
US20030050276A1 (en) * 2001-08-15 2003-03-13 Cunanan Crystal M. Treatment of tissue, instruments and work surfaces to remove infectious agents
JP2004516896A (ja) * 2000-12-29 2004-06-10 アップフロント・クロマトグラフィー・アー／エス 細胞外体液からの特異的生体高分子物質の体外捕獲
US20020131958A1 (en) * 2001-01-22 2002-09-19 John Chapman Method for purifying a biological composition
US7577577B2 (en) * 2001-01-31 2009-08-18 Dell Products L.P. Pull to customer order demand fulfillment system and method
US6518010B2 (en) * 2001-02-28 2003-02-11 Biopure Corporation Use of defibrinated blood for manufacture of a hemoglobin-based oxygen carrier
US6613505B2 (en) 2001-04-12 2003-09-02 Bioresource International, Inc. Composition and method for destruction of infetious prion proteins
US7659076B2 (en) * 2002-02-28 2010-02-09 Microsens Biophage Limited Binding of pathological forms of prion proteins
US7001715B2 (en) * 2002-02-28 2006-02-21 Biopure Corporation Purification of red blood cells by separation and diafiltration
WO2003073185A2 (en) * 2002-02-28 2003-09-04 Zetacon Corporation Predictive control system and method
GB0214007D0 (en) * 2002-06-18 2002-07-31 Common Services Agency Removal of prion infectivity
DK1573323T3 (da) * 2002-12-03 2012-01-23 Pathogen Removal & Diagnostic Technologies Inc Prion-proteinligander samt fremgangsmåder til anvendelse deraf
US7510848B2 (en) * 2003-04-04 2009-03-31 North Carolina State University Prion protein binding materials and methods of use
WO2004090102A2 (en) 2003-04-04 2004-10-21 American Red Cross Prion protein binding materials and methods of use
US20050054003A1 (en) * 2003-09-10 2005-03-10 Stenland Christopher J. Prion clearance using particulate metal oxides
CN1922207B (zh) 2004-02-27 2012-06-06 奥克特珐玛股份有限公司 提供纯化的、病毒安全的抗体制剂的方法
GB0416699D0 (en) * 2004-07-27 2004-09-01 Prometic Biosciences Ltd Prion protein ligands and methods of use
EP1865993A2 (en) * 2005-04-05 2007-12-19 Biopure Corporation Oxygenated polymerized hemoglobin solutions and their uses for tissue visualization
WO2006131768A2 (en) * 2005-06-10 2006-12-14 Prometic Biosciences Limited Triazines as protein binding ligands
US20070128693A1 (en) * 2005-12-06 2007-06-07 Advantek Serum Laboratories Limited3/F Method for the inactivation and removal of dengue virus from biological samples
CN101489570B (zh) * 2006-07-12 2013-02-20 旭化成医疗株式会社 从血液制剂中除去异常朊病毒的方法
JP2010515068A (ja) * 2006-12-29 2010-05-06 テキサス テック ユニバーシティー 生体液から感染性海綿状脳症因子を除去するための直交性方法
EP2027875A1 (en) * 2007-08-23 2009-02-25 Octapharma AG A Process for Isolation and Purification of a Target Protein free of Prion Protein (PrPSC)
US10172950B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
KR102170375B1 (ko) 2009-06-09 2020-10-27 프로롱 파마슈티컬스, 엘엘씨 헤모글로빈 조성물
US10172949B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
CN102675414A (zh) * 2011-03-08 2012-09-19 上海天伟生物制药有限公司 糖蛋白中去除/灭活朊病毒的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU605901B2 (en) * 1987-09-11 1991-01-24 Ares Trading S.A. Purification process
EP0313343B2 (en) * 1987-10-23 2003-07-23 Schering Corporation Method of purifying protein
DK0716610T3 (da) * 1993-08-26 2006-09-04 Genetics Inst Llc Humane knogle-morfogenetiske proteiner til anvendelse ved neural regenerering
DE4429558A1 (de) * 1994-08-19 1996-02-22 Sanorell Pharma Gmbh & Co Verfahren zur Herstellung von infektionsfreien pharmazeutischen Präparaten und/oder Nahrungsmitteln aus infektiösem Material

Also Published As

Publication number Publication date
TW390887B (en) 2000-05-21
WO1998000441A1 (en) 1998-01-08
CN1221425A (zh) 1999-06-30
CN1283660C (zh) 2006-11-08
AU718557B2 (en) 2000-04-13
DE69729217D1 (de) 2004-06-24
CN1743340A (zh) 2006-03-08
EP0954528B2 (en) 2011-09-07
ATE267212T1 (de) 2004-06-15
DE69729217T3 (de) 2012-03-15
EP0954528A1 (en) 1999-11-10
BR9710035A (pt) 1999-08-10
JP2000513377A (ja) 2000-10-10
DE69729217T2 (de) 2005-05-04
HK1019151A1 (en) 2000-01-14
JP4031833B2 (ja) 2008-01-09
ES2221957T3 (es) 2005-01-16
US5808011A (en) 1998-09-15
EP0954528B1 (en) 2004-05-19
CA2259632A1 (en) 1998-01-08
AU3580297A (en) 1998-01-21
CA2259632C (en) 2008-04-08

Similar Documents

Publication Publication Date Title
ES2221957T5 (es) Método para la eliminación cromatográfica de priones.
ES2689333T3 (es) Método de eliminación de contaminantes
ES2717683T3 (es) Métodos de preparación para una generación novedosa de productos de KLH biológicamente seguros usados para el tratamiento contra el cáncer, para el desarrollo de vacunas terapéuticas conjugadas y como agentes de exposición
CN116322920A (zh) 使用氧化硅吸附从血浆中纯化fviii
ES2717709T3 (es) Métodos de preparación para una generación novedosa de productos de KLH biológicamente seguros usados para el tratamiento de cáncer, para el desarrollo de vacunas terapéuticas conjugadas y como agentes de exposición
HK1088341A (en) A method for chromatographic removal of prions
HK1019151B (en) A method for chromatographic removal of prions