ES2235188T3 - Uso de liquidos quimicos fluorados para la fabricacion de medicamentos para el tratamiento por extirpacion criogenica. - Google Patents

Uso de liquidos quimicos fluorados para la fabricacion de medicamentos para el tratamiento por extirpacion criogenica.

Info

Publication number
ES2235188T3
ES2235188T3 ES96920456T ES96920456T ES2235188T3 ES 2235188 T3 ES2235188 T3 ES 2235188T3 ES 96920456 T ES96920456 T ES 96920456T ES 96920456 T ES96920456 T ES 96920456T ES 2235188 T3 ES2235188 T3 ES 2235188T3
Authority
ES
Spain
Prior art keywords
liquid
cryoprobe
lesion
around
fluorochemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96920456T
Other languages
English (en)
Inventor
Robert G Stern
Thomas H Shaffer
Marla R Wolfson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Temple Univ School of Medicine
Original Assignee
Temple Univ School of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Temple Univ School of Medicine filed Critical Temple Univ School of Medicine
Application granted granted Critical
Publication of ES2235188T3 publication Critical patent/ES2235188T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B18/0218—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques with open-end cryogenic probe, e.g. for spraying fluid directly on tissue or via a tissue-contacting porous tip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00059—Material properties
    • A61B2018/00089—Thermal conductivity
    • A61B2018/00101—Thermal conductivity low, i.e. thermally insulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
    • A61B2018/0022—Balloons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0212—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/378—Surgical systems with images on a monitor during operation using ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3925—Markers, e.g. radio-opaque or breast lesions markers ultrasonic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3933—Liquid markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2218/00—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2218/001—Details of surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body having means for irrigation and/or aspiration of substances to and/or from the surgical site
    • A61B2218/002—Irrigation

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

ESTA INVENCION ES UN PROCEDIMIENTO PARA EL TRATAMIENTO CRIOGENICO DE UNA LESION (20) QUE INCLUYE LAS ETAPAS DE ADMINISTRAR UN LIQUIDO FLUOROQUIMICO A LA LESION (20), COLOCAR AL MENOS UNA CRIOSONDA (26) EN EL INTERIOR DE LA LESION (20), Y HACER CIRCULAR UN FLUIDO CRIOGENICO QUE PROVOCA LA FORMACION DE UNA BOLA DE HIELO (30) EN LAS PROXIMIDADES DE LA CRIOSONDA (26), DE FORMA QUE LA BOLA DE HIELO (30) OBLITERE AL MENOS UNA PORCION DE LA LESION (20). EL LIQUIDO FLUOROQUIMICO SE UTILIZA PARA AUMENTAR EL PROCEDIMIENTO CRIOQUIRURGICO Y SE PERFUSIONA O SE INYECTA EN EL SITIO DE LESION Y/O ALREDEDOR DE ESTE, ANTES Y/O DURANTE LA APLICACION DE UNA CRIOSONDA (26) AL SITIO. EN UNA REALIZACION DE LA INVENCION, EL LIQUIDO FLUOROQUIMICO ACTUA COMO UN AGENTE DE CONTRASTE PARA MEJORAR LA FORMACION DE IMAGENES MEDICAS EN TIEMPO REAL DEL AREA DE LESION, Y MODIFICA EL MEDIO DENTRO Y ALREDEDOR DEL AREA DE LESION. EN OTRA REALIZACION DE LA INVENCION, EL LIQUIDO FLUOROQUIMICO AUMENTA LOS PROCEDIMIENTOS CRIOQUIRURGICOS CONTROLANDO EL TAMAÑO Y LA FORMA DE LAS BOLAS DE HIELO (30) FORMADAS DURANTE LOS PROCEDIMIENTOS CRIOQUIRURGICOS. EN ESTA REALIZACION, SE UTILIZA UN LIQUIDO FLUOROQUIMICO CON UNA CONDUCTIVIDAD TERMICA Y UN PUNTO DE CONGELACION ESCOGIDOS DE FORMA ADECUADA. DEPENDIENDO DE LAS PROPIEDADES TERMICAS ESCOGIDAS, EL LIQUIDO AUMENTA LA CONGELACION DEL AREA DIANA Y/O ESTIMULA LA CONDUCCION TERMICA PARA CONGELAR AREAS MAYORES, O LIMITA LA CONGELACION DEL AREA DIANA Y REDUCE LA CONDUCCION TERMICA. EN UNA REALIZACION QUE NO UTILIZA UNA CRIOSONDA, EL LIQUIDO SE ENFRIA HASTA UNA TEMPERATURA INFERIOR AL PUNTO DE CONGELACION DEL TEJIDO BIOLOGICO. ENTONCES EL LIQUIDO ENFRIADO SE INFUSIONA EN LA LESION CISTICA, O ALREDEDOR DE ESTA, PARA PRODUCIR ABLACION.
ES96920456T 1995-06-07 1996-05-21 Uso de liquidos quimicos fluorados para la fabricacion de medicamentos para el tratamiento por extirpacion criogenica. Expired - Lifetime ES2235188T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/487,386 US5741248A (en) 1995-06-07 1995-06-07 Fluorochemical liquid augmented cryosurgery

Publications (1)

Publication Number Publication Date
ES2235188T3 true ES2235188T3 (es) 2005-07-01

Family

ID=23935530

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96920456T Expired - Lifetime ES2235188T3 (es) 1995-06-07 1996-05-21 Uso de liquidos quimicos fluorados para la fabricacion de medicamentos para el tratamiento por extirpacion criogenica.

Country Status (9)

Country Link
US (1) US5741248A (es)
EP (1) EP0835078B1 (es)
JP (1) JP4155597B2 (es)
AT (1) ATE290343T1 (es)
AU (1) AU5875196A (es)
CA (1) CA2221513C (es)
DE (1) DE69634435T2 (es)
ES (1) ES2235188T3 (es)
WO (1) WO1996039960A1 (es)

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JPH11506635A (ja) 1999-06-15
EP0835078A1 (en) 1998-04-15
WO1996039960A1 (en) 1996-12-19
EP0835078A4 (en) 2000-04-26
DE69634435T2 (de) 2006-02-02
DE69634435D1 (de) 2005-04-14
AU5875196A (en) 1996-12-30
CA2221513A1 (en) 1996-12-19
JP4155597B2 (ja) 2008-09-24
US5741248A (en) 1998-04-21

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