ES2241197T3 - Inhibidores de serina-proteasa. - Google Patents

Inhibidores de serina-proteasa.

Info

Publication number
ES2241197T3
ES2241197T3 ES98966667T ES98966667T ES2241197T3 ES 2241197 T3 ES2241197 T3 ES 2241197T3 ES 98966667 T ES98966667 T ES 98966667T ES 98966667 T ES98966667 T ES 98966667T ES 2241197 T3 ES2241197 T3 ES 2241197T3
Authority
ES
Spain
Prior art keywords
baselineskip
seq
amino acids
sequence
type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98966667T
Other languages
English (en)
Spanish (es)
Inventor
Wolf-Georg Forssmann
Hans-Jurgen Magert
Ludger Standker
Peter Kreutzmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharis Biotec GmbH
Original Assignee
Pharis Biotec GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1998100363 external-priority patent/DE19800363A1/de
Application filed by Pharis Biotec GmbH filed Critical Pharis Biotec GmbH
Application granted granted Critical
Publication of ES2241197T3 publication Critical patent/ES2241197T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8135Kazal type inhibitors, e.g. pancreatic secretory inhibitor, ovomucoid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Diabetes (AREA)
  • Surgery (AREA)
  • Rheumatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES98966667T 1997-12-23 1998-12-23 Inhibidores de serina-proteasa. Expired - Lifetime ES2241197T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19757572 1997-12-23
DE19757572 1997-12-23
DE1998100363 DE19800363A1 (de) 1998-01-08 1998-01-08 Serin-Proteinase-Inhibitoren
DE19800363 1998-01-08

Publications (1)

Publication Number Publication Date
ES2241197T3 true ES2241197T3 (es) 2005-10-16

Family

ID=26042785

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98966667T Expired - Lifetime ES2241197T3 (es) 1997-12-23 1998-12-23 Inhibidores de serina-proteasa.

Country Status (8)

Country Link
US (1) US7045594B1 (fr)
EP (1) EP1040190B1 (fr)
JP (2) JP4358989B2 (fr)
AT (1) ATE292682T1 (fr)
CA (1) CA2315976C (fr)
DE (1) DE59812724D1 (fr)
ES (1) ES2241197T3 (fr)
WO (1) WO1999033974A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6939851B1 (en) 1999-06-22 2005-09-06 Pharis Biotec Gmbh Serine proteinase inhibitors
AU2001235829A1 (en) * 2000-03-02 2001-09-12 Isis Innovation Limited Mutations in spink5 responsible for netherton's syndrome and atopic diseases
EP1299412A2 (fr) * 2000-06-30 2003-04-09 Incyte Genomics, Inc. Molecules de modification et de maintenance de proteines
JP2005500005A (ja) * 2000-12-08 2005-01-06 インサイト・ゲノミックス・インコーポレイテッド タンパク質修飾分子とメンテナンス分子
WO2002066513A2 (fr) * 2001-02-19 2002-08-29 Ipf Pharmaceuticals Gmbh Fragments humains de lekti circulants hf7072, hf7638 et hf14448 ainsi que leur utilisation
DE102009010942A1 (de) 2009-02-27 2010-09-02 Universitätsklinikum Schleswig-Holstein Serinprotease-Inhibitoren zur spezifischen Inhibition von Gewebs-Kallikreinen
HUP0900319A2 (en) * 2009-05-25 2011-01-28 Eotvos Lorand Tudomanyegyetem New peptides, method of producing therof and use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6427473A (en) * 1987-07-23 1989-01-30 Mochida Pharm Co Ltd Human pancreas-secreting trypsin inhibitor and production thereof
AU7257994A (en) * 1993-07-09 1995-02-06 Michael Laskowski Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain
WO1997015670A1 (fr) * 1995-10-25 1997-05-01 Arris Pharmaceutical Corporation Nouveaux inhibiteurs de la subtilisine
JP2002508167A (ja) * 1997-12-18 2002-03-19 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド 110個のヒト分泌タンパク質

Also Published As

Publication number Publication date
EP1040190A1 (fr) 2000-10-04
DE59812724D1 (de) 2005-05-12
JP2009273468A (ja) 2009-11-26
CA2315976A1 (fr) 1999-07-08
JP2002505081A (ja) 2002-02-19
JP4358989B2 (ja) 2009-11-04
WO1999033974A1 (fr) 1999-07-08
US7045594B1 (en) 2006-05-16
EP1040190B1 (fr) 2005-04-06
CA2315976C (fr) 2011-06-28
ATE292682T1 (de) 2005-04-15

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