ES2281088T3 - Procedimiento para la produccion microbiana de aminoacidos mediante un aumento de la actividad de vehiculos de exportacion. - Google Patents

Procedimiento para la produccion microbiana de aminoacidos mediante un aumento de la actividad de vehiculos de exportacion. Download PDF

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Publication number
ES2281088T3
ES2281088T3 ES96946220T ES96946220T ES2281088T3 ES 2281088 T3 ES2281088 T3 ES 2281088T3 ES 96946220 T ES96946220 T ES 96946220T ES 96946220 T ES96946220 T ES 96946220T ES 2281088 T3 ES2281088 T3 ES 2281088T3
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Spain
Prior art keywords
gene
export
lyse
amino acids
sequence
Prior art date
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Expired - Lifetime
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ES96946220T
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English (en)
Spanish (es)
Inventor
Marina Vrlijc
Lothar Eggeling
Hermann Sahm
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Forschungszentrum Juelich GmbH
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Forschungszentrum Juelich GmbH
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES96946220T 1995-12-22 1996-12-18 Procedimiento para la produccion microbiana de aminoacidos mediante un aumento de la actividad de vehiculos de exportacion. Expired - Lifetime ES2281088T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19548222 1995-12-22
DE19548222A DE19548222A1 (de) 1995-12-22 1995-12-22 Verfahren zur mikrobiellen Herstellung von Aminosäuren durch gesteigerte Aktivität von Exportcarriern

Publications (1)

Publication Number Publication Date
ES2281088T3 true ES2281088T3 (es) 2007-09-16

Family

ID=7781070

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96946220T Expired - Lifetime ES2281088T3 (es) 1995-12-22 1996-12-18 Procedimiento para la produccion microbiana de aminoacidos mediante un aumento de la actividad de vehiculos de exportacion.

Country Status (16)

Country Link
US (1) US6858406B1 (2)
EP (1) EP0868527B1 (2)
JP (1) JP3942194B2 (2)
KR (1) KR100444621B1 (2)
CN (1) CN1283797C (2)
AR (1) AR048561A1 (2)
AU (1) AU724536B2 (2)
BR (1) BR9612666A (2)
CA (1) CA2241111C (2)
DE (2) DE19548222A1 (2)
DK (1) DK0868527T3 (2)
ES (1) ES2281088T3 (2)
MX (1) MX9805050A (2)
RU (1) RU2225883C2 (2)
WO (1) WO1997023597A2 (2)
ZA (1) ZA9610768B (2)

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KR102801078B1 (ko) * 2022-06-23 2025-04-24 씨제이제일제당 (주) L-히스티딘 배출 단백질 및 이를 이용한 l-히스티딘 생산 방법
CN115806601B (zh) * 2022-10-24 2024-12-20 天津科技大学 一种转录调控因子LysG突变体及其应用

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JPS5618596A (en) * 1979-07-23 1981-02-21 Ajinomoto Co Inc Production of l-lysine through fermentation process
JPS575693A (en) * 1980-06-13 1982-01-12 Ajinomoto Co Inc Production of l-arginine through fermentation process
DE4400926C1 (de) * 1994-01-14 1995-06-01 Forschungszentrum Juelich Gmbh Herstellung von L-Isoleucin mittels rekombinanter Mikroorganismen mit deregulierter Threonindehydratase

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DE59611412D1 (de) 2007-02-22
CA2241111A1 (en) 1997-07-03
EP0868527A2 (de) 1998-10-07
ZA9610768B (en) 1998-07-31
JP3942194B2 (ja) 2007-07-11
DK0868527T3 (da) 2007-05-07
JP2000507086A (ja) 2000-06-13
CA2241111C (en) 2009-09-22
US6858406B1 (en) 2005-02-22
MX9805050A (es) 1998-10-31
WO1997023597A3 (de) 1997-10-09
KR100444621B1 (ko) 2004-11-16
AR048561A1 (es) 2006-05-10
CN1283797C (zh) 2006-11-08
AU1921897A (en) 1997-07-17
WO1997023597A2 (de) 1997-07-03
EP0868527B1 (de) 2007-01-10
RU2225883C2 (ru) 2004-03-20
CN1209169A (zh) 1999-02-24
KR19990076708A (ko) 1999-10-15
DE19548222A1 (de) 1997-06-26
BR9612666A (pt) 1999-10-05
AU724536B2 (en) 2000-09-21

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