ES2311472T3 - Nuevos genes de control del ciclo celular y proteinas codificadas por los mismos. - Google Patents

Nuevos genes de control del ciclo celular y proteinas codificadas por los mismos. Download PDF

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Publication number
ES2311472T3
ES2311472T3 ES00965026T ES00965026T ES2311472T3 ES 2311472 T3 ES2311472 T3 ES 2311472T3 ES 00965026 T ES00965026 T ES 00965026T ES 00965026 T ES00965026 T ES 00965026T ES 2311472 T3 ES2311472 T3 ES 2311472T3
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ES
Spain
Prior art keywords
nucleic acid
seq
themselves
control
cell cycle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00965026T
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English (en)
Inventor
Paul R Russell
Jorge E Vialard
Michael N Boddy
Paul A Shanahan
Antonia Lopez-Girona
Cecile-Marie D D Denis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Scripps Research Institute
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Janssen Pharmaceutica NV
Scripps Research Institute
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Application granted granted Critical
Publication of ES2311472T3 publication Critical patent/ES2311472T3/es
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Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Ácido nucleico seleccionado de entre el grupo constituido por: (a) un ácido nucleico que codifica una proteína humana que presenta la secuencia aminoácida representada por SEC ID nº:2, por SEC ID nº:4, por SEC ID nº:8, o por SEC ID nº:10 (b) una variante alélica de un ácido nucleico según (a): (c) un ácido nucleico que codifica una parte biológicamente activa de una proteína codificada por un ácido nucleico según cualquiera de (a) a (b), en el que la actividad biológica es una actividad de unión a Cds 1; o (d) un ácido nucleico que codifica una proteína que presenta una identidad secuencial de por lo menos 90%, con respecto a la proteína representada en SEC ID n os : 2, 4, 8 ó 10.
ES00965026T 1999-09-14 2000-09-14 Nuevos genes de control del ciclo celular y proteinas codificadas por los mismos. Expired - Lifetime ES2311472T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15383699P 1999-09-14 1999-09-14

Publications (1)

Publication Number Publication Date
ES2311472T3 true ES2311472T3 (es) 2009-02-16

Family

ID=22548950

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00965026T Expired - Lifetime ES2311472T3 (es) 1999-09-14 2000-09-14 Nuevos genes de control del ciclo celular y proteinas codificadas por los mismos.

Country Status (15)

Country Link
US (3) US6440732B1 (es)
EP (1) EP1214453B1 (es)
JP (1) JP4871468B2 (es)
KR (2) KR100851511B1 (es)
AT (1) ATE404693T1 (es)
AU (1) AU784443B2 (es)
CA (1) CA2385266C (es)
DE (1) DE60039895D1 (es)
DK (1) DK1214453T3 (es)
ES (1) ES2311472T3 (es)
IL (2) IL148595A0 (es)
NO (1) NO20021255L (es)
NZ (1) NZ518236A (es)
WO (1) WO2001020038A1 (es)
ZA (1) ZA200202863B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2507863A1 (en) * 2002-12-04 2004-06-17 Algos Therapeutics, Inc. Methods and materials for modulating trpm2
US7396669B2 (en) * 2004-06-30 2008-07-08 The Scripps Research Institute Mammalian endonucleases and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5801154A (en) * 1993-10-18 1998-09-01 Isis Pharmaceuticals, Inc. Antisense oligonucleotide modulation of multidrug resistance-associated protein
US5552390A (en) * 1993-12-09 1996-09-03 The Board Of Regents Of The University Of Nebraska Phosphorothioate inhibitors of metastatic breast cancer
WO1998041648A2 (en) * 1997-03-20 1998-09-24 Variagenics, Inc. Target genes for allele-specific drugs
US5977341A (en) * 1998-11-20 1999-11-02 Isis Pharmaceuticals Inc. Antisense modulation of inhibitor-kappa B kinase-beta expression
US7396669B2 (en) * 2004-06-30 2008-07-08 The Scripps Research Institute Mammalian endonucleases and methods of use

Also Published As

Publication number Publication date
CA2385266A1 (en) 2001-03-22
JP4871468B2 (ja) 2012-02-08
EP1214453B1 (en) 2008-08-13
KR20070043872A (ko) 2007-04-25
EP1214453A4 (en) 2003-02-19
ATE404693T1 (de) 2008-08-15
DK1214453T3 (da) 2008-10-13
WO2001020038A1 (en) 2001-03-22
EP1214453A1 (en) 2002-06-19
US20070213256A1 (en) 2007-09-13
NO20021255D0 (no) 2002-03-13
US20070072794A1 (en) 2007-03-29
KR20020064781A (ko) 2002-08-09
US7214790B2 (en) 2007-05-08
NZ518236A (en) 2004-02-27
KR100851511B1 (ko) 2008-08-11
NO20021255L (no) 2002-05-03
AU784443B2 (en) 2006-04-06
JP2003509069A (ja) 2003-03-11
CA2385266C (en) 2011-05-24
DE60039895D1 (de) 2008-09-25
US6440732B1 (en) 2002-08-27
ZA200202863B (en) 2003-09-23
IL148595A (en) 2008-11-26
KR100817010B1 (ko) 2008-03-27
AU7581700A (en) 2001-04-17
IL148595A0 (en) 2002-09-12
US7479541B2 (en) 2009-01-20

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