ES2336911T3 - Trans-9,10-dehidroepotilonas c y d, sus analogos y procedimientos de preparacion. - Google Patents

Trans-9,10-dehidroepotilonas c y d, sus analogos y procedimientos de preparacion. Download PDF

Info

Publication number: ES2336911T3
Authority: ES; Spain
Prior art keywords: compound; baselineskip; solution; product; bis
Prior art date: 2002-11-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

ES03768730T

Other languages

English (en)

Spanish (es)

Inventor

Yong Li

Kurt Sundermann

Li Tang

David Myles

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kosan Biosciences Inc

Original Assignee

Kosan Biosciences Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-07

Filing date

2003-11-07

Publication date

2010-04-19

2003-11-07 Application filed by Kosan Biosciences Inc filed Critical Kosan Biosciences Inc

2010-04-19 Application granted granted Critical

2010-04-19 Publication of ES2336911T3 publication Critical patent/ES2336911T3/es

2023-11-07 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

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Classifications

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- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
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Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

ES03768730T 2002-11-07 2003-11-07 Trans-9,10-dehidroepotilonas c y d, sus analogos y procedimientos de preparacion. Expired - Lifetime ES2336911T3 (es)

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US42535202P	2002-11-07	2002-11-07
US425352P		2002-11-07
US47374303P	2003-05-27	2003-05-27
US473743P		2003-05-27

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ES03768730T Expired - Lifetime ES2336911T3 (es)	2002-11-07	2003-11-07	Trans-9,10-dehidroepotilonas c y d, sus analogos y procedimientos de preparacion.
ES09012671T Expired - Lifetime ES2436296T3 (es)	2002-11-07	2003-11-07	Trans-9,10-dehidroepotilona C y trans-9,10-dehidroepotilona D, sus análogos y procedimientos de fabricación de las mismas

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US (2)	US20040152708A1 (2)
EP (3)	EP2135867B1 (2)
JP (3)	JP4641941B2 (2)
KR (2)	KR100966667B1 (2)
AT (1)	ATE452888T1 (2)
AU (1)	AU2003291337B2 (2)
CA (1)	CA2505368C (2)
CY (1)	CY1110295T1 (2)
DE (1)	DE60330703D1 (2)
DK (1)	DK1562941T3 (2)
ES (2)	ES2336911T3 (2)
PT (1)	PT1562941E (2)
SI (1)	SI1562941T1 (2)
WO (1)	WO2004043954A2 (2)

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US7384964B2 (en) *	2002-08-23	2008-06-10	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US7649006B2 (en)	2002-08-23	2010-01-19	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto and analogues thereof
DE60330407D1 (de)	2002-08-23	2010-01-14	Sloan Kettering Inst Cancer	Synthese von Epothilonen, Zwischenprodukte davon, Analoga und ihre Verwendung
US6921769B2 (en)	2002-08-23	2005-07-26	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto and analogues thereof
CN101088998A (zh) *	2002-11-07	2007-12-19	科桑生物科学公司	反式－9,10－脱氢埃坡霉素c和d,其类似物以及制备这些化合物的方法
ES2336911T3 (es) *	2002-11-07	2010-04-19	Kosan Biosciences, Inc.	Trans-9,10-dehidroepotilonas c y d, sus analogos y procedimientos de preparacion.
BRPI0408891A (pt) *	2003-03-28	2006-04-11	Kosan Biosciences Inc	dispositivos, métodos, e composições para prevenir restenose
EP1670487A4 (en) *	2003-10-09	2008-05-21	Kosan Biosciences Inc	THERAPEUTIC FORMULATIONS
US20050215604A1 (en) *	2004-03-26	2005-09-29	Kosan Biosciences, Inc.	Combination therapies with epothilones and carboplatin
CN105061577A (zh) *	2006-12-14	2015-11-18	爱勒让治疗公司	双巯基大环化系统
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AU2008232709C1 (en)	2007-03-28	2015-01-15	President And Fellows Of Harvard College	Stitched polypeptides
US8030503B2 (en)	2007-05-11	2011-10-04	Kosan Biosciences Incorporated	Process for the preparation of epothilones
WO2008141234A2 (en) *	2007-05-11	2008-11-20	Kosan Biosciences Incorporated	Methods of making epothilones
WO2010083347A2 (en)	2009-01-14	2010-07-22	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles
US20130072439A1 (en)	2009-09-22	2013-03-21	Huw M. Nash	Peptidomimetic macrocycles
KR20170058446A (ko)	2010-08-13	2017-05-26	에일러론 테라퓨틱스 인코포레이티드	펩티도미메틱 거대고리
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2003
- 2003-11-07 ES ES03768730T patent/ES2336911T3/es not_active Expired - Lifetime
- 2003-11-07 US US10/703,404 patent/US20040152708A1/en not_active Abandoned
- 2003-11-07 WO PCT/US2003/035411 patent/WO2004043954A2/en not_active Ceased
- 2003-11-07 SI SI200331732T patent/SI1562941T1/sl unknown
- 2003-11-07 PT PT03768730T patent/PT1562941E/pt unknown
- 2003-11-07 EP EP09012671.5A patent/EP2135867B1/en not_active Expired - Lifetime
- 2003-11-07 JP JP2005507102A patent/JP4641941B2/ja not_active Expired - Fee Related
- 2003-11-07 DE DE60330703T patent/DE60330703D1/de not_active Expired - Lifetime
- 2003-11-07 CA CA2505368A patent/CA2505368C/en not_active Expired - Fee Related
- 2003-11-07 EP EP03768730A patent/EP1562941B1/en not_active Expired - Lifetime
- 2003-11-07 DK DK03768730.8T patent/DK1562941T3/da active
- 2003-11-07 KR KR1020057008039A patent/KR100966667B1/ko not_active Expired - Fee Related
- 2003-11-07 AU AU2003291337A patent/AU2003291337B2/en not_active Ceased
- 2003-11-07 KR KR1020107000780A patent/KR100996996B1/ko not_active Expired - Fee Related
- 2003-11-07 AT AT03768730T patent/ATE452888T1/de active
- 2003-11-07 ES ES09012671T patent/ES2436296T3/es not_active Expired - Lifetime
- 2003-11-07 EP EP09012860A patent/EP2135868A1/en not_active Withdrawn
2008
- 2008-07-11 US US12/172,174 patent/US20090186927A1/en not_active Abandoned
2010
- 2010-03-19 CY CY20101100250T patent/CY1110295T1/el unknown
- 2010-10-08 JP JP2010228356A patent/JP5679757B2/ja not_active Expired - Fee Related
2013
- 2013-07-16 JP JP2013147528A patent/JP2013213054A/ja active Pending

Also Published As

Publication number	Publication date
EP1562941B1 (en)	2009-12-23
JP5679757B2 (ja)	2015-03-04
CY1110295T1 (el)	2015-01-14
WO2004043954A3 (en)	2004-11-18
JP2013213054A (ja)	2013-10-17
DE60330703D1 (de)	2010-02-04
EP2135868A1 (en)	2009-12-23
KR100966667B1 (ko)	2010-06-29
EP2135867B1 (en)	2013-09-25
DK1562941T3 (da)	2010-04-19
KR100996996B1 (ko)	2010-11-25
JP4641941B2 (ja)	2011-03-02
KR20050084959A (ko)	2005-08-29
KR20100018075A (ko)	2010-02-16
JP2011006480A (ja)	2011-01-13
ES2436296T3 (es)	2013-12-30
ATE452888T1 (de)	2010-01-15
PT1562941E (pt)	2010-01-25
JP2006510743A (ja)	2006-03-30
CA2505368A1 (en)	2004-05-27
SI1562941T1 (sl)	2010-05-31
EP1562941A2 (en)	2005-08-17
WO2004043954A2 (en)	2004-05-27
AU2003291337B2 (en)	2010-09-09
AU2003291337A1 (en)	2004-06-03
US20040152708A1 (en)	2004-08-05
CA2505368C (en)	2011-09-20
US20090186927A1 (en)	2009-07-23
EP2135867A1 (en)	2009-12-23

Publication	Publication Date	Title
ES2336911T3 (es)	2010-04-19	Trans-9,10-dehidroepotilonas c y d, sus analogos y procedimientos de preparacion.
JP2006510743A5 (2)	2006-12-21
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US20020045609A1 (en)	2002-04-18	Epothilone derivatives and methods for making and using the same
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US6867305B2 (en)	2005-03-15	Synthesis of epothilones, intermediates thereto and analogues thereof
US20020058286A1 (en)	2002-05-16	Synthesis of epothilones, intermediates thereto and analogues thereof
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US20030023082A1 (en)	2003-01-30	Epothilone derivatives and methods for making and using the same
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