ES238207A1 - Un procedimiento para producir tetraciclina - Google Patents

Un procedimiento para producir tetraciclina

Info

Publication number: ES238207A1
Authority: ES; Spain
Prior art keywords: tetracycline; chlortetracycline; fermentations; hydrogen; chlorination
Prior art date: 1956-11-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES0238207A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wyeth Holdings LLC

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1956-11-02

Filing date

1957-10-22

Publication date

1958-04-16

1957-10-22 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

1958-04-16 Publication of ES238207A1 publication Critical patent/ES238207A1/es

Status Expired legal-status Critical Current

Links

239000004098 Tetracycline Substances 0.000 title abstract 3
229960002180 tetracycline Drugs 0.000 title abstract 3
238000005660 chlorination reaction Methods 0.000 title abstract 2
238000000855 fermentation Methods 0.000 title abstract 2
230000004151 fermentation Effects 0.000 title abstract 2
239000003112 inhibitor Substances 0.000 title abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
229930101283 tetracycline Natural products 0.000 abstract 2
235000019364 tetracycline Nutrition 0.000 abstract 2
150000003522 tetracyclines Chemical class 0.000 abstract 2
SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
241000187747 Streptomyces Species 0.000 abstract 1
238000010564 aerobic fermentation Methods 0.000 abstract 1
-1 alkyl radical Chemical class 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Inorganic materials 0.000 abstract 1
229910052801 chlorine Chemical group 0.000 abstract 1
239000000460 chlorine Chemical group 0.000 abstract 1
CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 abstract 1
CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
244000005700 microbiome Species 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P29/00—Preparation of compounds containing a naphthacene ring system, e.g. tetracycline
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/889—Streptomyces aureofaciens

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES0238207A 1956-11-02 1957-10-22 Un procedimiento para producir tetraciclina Expired ES238207A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US619948A US2923668A (en)	1956-11-02	1956-11-02	Chlorination inhibitors in chlortetracycline-tetracycline fermentations

Publications (1)

Publication Number	Publication Date
ES238207A1 true ES238207A1 (es)	1958-04-16

Family

ID=24483964

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES0238207A Expired ES238207A1 (es)	1956-11-02	1957-10-22	Un procedimiento para producir tetraciclina

Country Status (2)

Country	Link
US (1)	US2923668A (es)
ES (1)	ES238207A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1074217B (de) *	1958-04-10	1960-01-28	SPOFA Sdruzenl podnikü pro zdravotnickou vyrobu, Prag	Verfahren zur Herstellung von Tetracyclin
US2996499A (en) *	1958-06-20	1961-08-15	American Cyanamid Co	Cosynthetic factor-1, and its production
US3425911A (en) *	1964-06-13	1969-02-04	Spofa Vereinigte Pharma Werke	Method of producing tetracycline

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE530983A (es) *	1953-09-28
NL103776C (es) *	1953-12-04
GB781843A (en) *	1956-02-21	1957-08-28	American Cyanamid Co	Pretreatment of aqueous nutrient-containing fermentation media to improve the yield of tetracycline therefrom

1956
- 1956-11-02 US US619948A patent/US2923668A/en not_active Expired - Lifetime
1957
- 1957-10-22 ES ES0238207A patent/ES238207A1/es not_active Expired

Also Published As

Publication number	Publication date
US2923668A (en)	1960-02-02

Similar Documents

Publication	Publication Date	Title
ES235737A1 (es)	1957-12-01	UN MÉTODO DE PREPARACIoN DE ANTIBIoTICOS DE DEMETILTITRACICLINA
ES264960A1 (es)	1961-05-16	Procedimiento de obtenciën de composiciones reveladoras fotograficas
ES238208A1 (es)	1958-04-16	Un procedimiento de producir tetraciclina
ES385907A1 (es)	1974-01-01	Procedimiento de desdoblamiento para la produccion de acido6-aminopenicilanico.
ES240761A1 (es)	1958-11-01	Un metodo de producir tetraciclinas
ES318832A1 (es)	1966-08-01	Procedimiento para el cultivo de streptomyces ochrosporus de efecto antibiotico.
ES232870A1 (es)	1957-05-16	UN MÉTODO DE PRODUCCIoN DE áCIDO1-GLUTáMICO
GR18728B (el)	1958-05-12	Μεθοδος παρασκευης ενωσεων σειρας τετρακυκλινης.
ES240767A1 (es)	1958-11-01	Un metodo para preparar compuestos de la serie de la tetraciclina
GB1252792A (es)	1971-11-10
GB836657A (en)	1960-06-09	Production of tetracycline
ES317908A1 (es)	1966-06-16	Un procedimiento para la produccion de un antibiotico.
GB930969A (en)	1963-07-10	Process for the production of 7-chloro-6-demethyltetracycline
ES422625A1 (es)	1976-09-01	Un procedimiento para la produccion de bicilomicina.
ES272079A1 (es)	1962-06-16	Procedimiento para la producción de compuestos heterocíclicos
ES228089A1 (es)	1956-08-01	UN MÉTODO DE PRODUCCIoN DE UN ANTIBIoTICO
ES315944A1 (es)	1966-02-16	Procedimiento de produccion de alanosina.
ES220052A1 (es)	1955-12-16	Un procedimiento para producir el antibiótico jn-21
ES389369A1 (es)	1974-03-16	Procedimiento para la produccion de piperidil - furanonas sustituidas.
ES343773A1 (es)	1968-12-01	Procedimiento microbiologico para la produccion de licope- no.
GB934527A (en)	1963-08-21	Improvements in or relating to the production of antibiotics
ES373678A1 (es)	1972-05-16	Un metodo para cultivar un microorganismo aerobio.
GR18726B (el)	1958-05-12	Μεθοδος παρασκευης ενωσεων σειρας τετρακυκλινης.
GB992119A (en)	1965-05-19	Antibiotics
ES245473A1 (es)	1959-04-01	Un procedimiento de producir tetraciclina y bromotetraciclina