ES2422739T3 - Composición para el diagnóstico, prevención o tratamiento de enfermedades relacionadas con células que expresan IL-8 o GRO-, que comprende MSC de UCB - Google Patents

Composición para el diagnóstico, prevención o tratamiento de enfermedades relacionadas con células que expresan IL-8 o GRO-, que comprende MSC de UCB

Info

Publication number
ES2422739T3
ES2422739T3 ES08793529T ES08793529T ES2422739T3 ES 2422739 T3 ES2422739 T3 ES 2422739T3 ES 08793529 T ES08793529 T ES 08793529T ES 08793529 T ES08793529 T ES 08793529T ES 2422739 T3 ES2422739 T3 ES 2422739T3
Authority
ES
Spain
Prior art keywords
prevention
ucb
gro
msc
diagnosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08793529T
Other languages
English (en)
Inventor
Jong Wook Chang
Dal-Soo Kim
Yoon-Sun Yang
Won Il Oh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medipost Co Ltd
Original Assignee
Medipost Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medipost Co Ltd filed Critical Medipost Co Ltd
Application granted granted Critical
Publication of ES2422739T3 publication Critical patent/ES2422739T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Una composición farmacéutica para uso en la prevención de tumores cerebrales, en la que la composiciónfarmacéutica comprende citoblastos mesenquimatosos aislados de sangre del cordón umbilical y/o citoblastosmesenquimatosos propagados a partir de dichos citoblastos mesenquimatosos.
ES08793529T 2007-08-29 2008-08-27 Composición para el diagnóstico, prevención o tratamiento de enfermedades relacionadas con células que expresan IL-8 o GRO-, que comprende MSC de UCB Active ES2422739T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR20070087228 2007-08-29
US97296607P 2007-09-17 2007-09-17
KR1020080067247A KR101039235B1 (ko) 2007-08-29 2008-07-10 제대혈 유래 간엽줄기세포를 포함하는 인터루킨-8 또는지알오-알파 발현 세포가 관련된 질병의 진단, 예방 또는치료용 조성물
US8973308P 2008-08-18 2008-08-18
PCT/KR2008/005026 WO2009028870A2 (en) 2007-08-29 2008-08-27 Composition for the diagnosis, prevention or treatment of diseases related to cells expressing il-8 or gro-alpha, comprising ucb-mscs

Publications (1)

Publication Number Publication Date
ES2422739T3 true ES2422739T3 (es) 2013-09-13

Family

ID=40388015

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08793529T Active ES2422739T3 (es) 2007-08-29 2008-08-27 Composición para el diagnóstico, prevención o tratamiento de enfermedades relacionadas con células que expresan IL-8 o GRO-, que comprende MSC de UCB

Country Status (10)

Country Link
US (2) US8506948B2 (es)
EP (1) EP2180896B1 (es)
JP (1) JP5529021B2 (es)
KR (1) KR101039235B1 (es)
CN (2) CN102776285A (es)
AU (1) AU2008293208A1 (es)
CA (1) CA2692232C (es)
ES (1) ES2422739T3 (es)
SG (1) SG184701A1 (es)
WO (1) WO2009028870A2 (es)

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KR101039235B1 (ko) 2007-08-29 2011-06-07 메디포스트(주) 제대혈 유래 간엽줄기세포를 포함하는 인터루킨-8 또는지알오-알파 발현 세포가 관련된 질병의 진단, 예방 또는치료용 조성물
KR20240052847A (ko) 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
US20120087868A1 (en) 2010-10-08 2012-04-12 Gabriele Todd Nanoparticle-loaded cells
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
US9428565B2 (en) 2011-01-31 2016-08-30 The General Hospital Corporation Treatment and bioluminescent visualization using multimodal TRAIL molecules
WO2012121577A2 (ko) * 2011-03-10 2012-09-13 이화여자대학교 산학협력단 Ｐｔｅｎ을 포함하는 줄기세포의 조직 재생능 강화용 조성물
JP6104896B2 (ja) 2011-06-01 2017-03-29 アントフロゲネシス コーポレーション 胎盤幹細胞を使用する疼痛の治療
US8961956B2 (en) 2011-11-30 2015-02-24 Ocata Therapeutics, Inc. Mesenchymal stromal cells and uses related thereto
SI2785359T1 (sl) * 2011-11-30 2018-11-30 Astellas Institute For Regenerative Medicine Mezenhimske stromalne celice in uporabe povezane z njimi
US20130171115A1 (en) * 2011-12-30 2013-07-04 Gang Li Cell-mediated gene therapy for cancer using mesenchymal stem cells expressing a suicide gene
JP2015506697A (ja) * 2012-02-01 2015-03-05 ポステック アカデミー‐インダストリー ファウンデーション １２量体ｔｒａｉｌ及びｈｓｖ−ｔｋ自殺遺伝子を同時に発現するベクター並びにそれを用いた抗癌幹細胞治療剤
CN102731658B (zh) * 2012-05-15 2014-07-30 山东大学 一种Tat PTD-Endostatin重组蛋白及其制备方法与应用
HK1208054A1 (en) 2012-07-12 2016-02-19 爱姆斯坦生物技术公司 Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
EP3473708B1 (en) 2012-07-24 2021-01-27 The General Hospital Corporation Oncolytic virus therapy for resistant tumors
WO2014035474A1 (en) 2012-08-30 2014-03-06 The General Hospital Corporation Compositions and methods for treating cancer
GB201220573D0 (en) * 2012-11-15 2013-01-02 Univ Central Lancashire Methods of diagnosing proliferative disorders
CN103602625B (zh) * 2013-08-16 2015-09-30 苏州大学 含有重组腺病毒质粒的大肠杆菌及重组腺病毒的应用
WO2015089280A1 (en) * 2013-12-11 2015-06-18 The General Hospital Corporation Stem cell delivered oncolytic herpes simplex virus and methods for treating brain tumors
JP6519727B2 (ja) * 2014-09-17 2019-05-29 国立大学法人山口大学 間葉系幹細胞の培養方法、および肝機能障害用治療剤の製造方法
KR101850780B1 (ko) * 2015-03-06 2018-04-23 아주대학교산학협력단 암 치료용 세포 치료제 및 이의 병용 요법
CN104726411B (zh) * 2015-03-27 2017-06-23 中国人民解放军军事医学科学院基础医学研究所 抑制肿瘤生长的重组间充质干细胞及其制备方法与应用
EP3283529B1 (en) * 2015-04-17 2023-06-07 The General Hospital Corporation Agents, systems and methods for treating cancer
CN110168092A (zh) * 2016-12-28 2019-08-23 特朗斯吉有限公司 溶瘤病毒和治疗分子
SG11202004680UA (en) 2017-11-22 2020-06-29 Mesoblast Int Sarl Cellular compositions and methods of treatment i
CN108018287A (zh) * 2018-01-10 2018-05-11 扬州大学 一种抑制山羊卵泡颗粒细胞增殖的特异siRNA及方法
CN108553478B (zh) * 2018-04-02 2020-03-20 杭州师范大学 一种septin基因shRNA在制备septin基因活性抑制剂中的应用
US10835558B2 (en) * 2018-04-16 2020-11-17 Brahm Holdings, Inc. Mammalian birth tissue composition for tumor treatment
AU2020325825B2 (en) * 2019-08-05 2026-02-05 Mesoblast International Sarl Cellular compositions comprising viral vectors and methods of treatment

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2287447T3 (es) 2002-02-19 2007-12-16 Medipost, Co., Ltd. Metodos de aislamiento y expansion del cultivo de celulas troncales/madre mesenquimatosas a partir de sangre del cordon umbilical, y metodo de diferenciacion de celulas troncales/madre mesenquimatosas derivadas de sangre del cordon umbilical en diversos tejidos mesenquimatosos.
KR20040022134A (ko) * 2002-09-06 2004-03-11 송준석 인간 간엽줄기 세포와 p53 분비 아데노바이러스를 이용한항암치료방법
US20060019256A1 (en) * 2003-06-09 2006-01-26 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
WO2005007176A1 (ja) * 2003-06-27 2005-01-27 Renomedix Institute Inc. 間葉系細胞を有効成分とする体内投与用脳神経疾患治療薬
CN1984899B (zh) * 2004-05-12 2011-07-27 先灵公司 Cxcr1和cxcr2趋化因子拮抗剂
PL1789534T3 (pl) * 2004-08-16 2015-03-31 Cellresearch Corp Pte Ltd Wyodrębnienie komórek macierzystych/progenitorowych z błony owodniowej pępowiny
JP2006345726A (ja) * 2005-06-14 2006-12-28 Hamamatsu Univ School Of Medicine 脳腫瘍治療用発現ベクター
WO2007011693A2 (en) 2005-07-14 2007-01-25 Medistem Laboratories, Inc. Compositions of placentally-derived stem cells for the treatment of cancer
KR101022401B1 (ko) * 2005-09-29 2011-03-15 아주대학교산학협력단 자살유전자를 발현하는 중간엽 줄기세포를 포함하는 암치료용 조성물
KR101039235B1 (ko) 2007-08-29 2011-06-07 메디포스트(주) 제대혈 유래 간엽줄기세포를 포함하는 인터루킨-8 또는지알오-알파 발현 세포가 관련된 질병의 진단, 예방 또는치료용 조성물

Also Published As

Publication number Publication date
CN102776285A (zh) 2012-11-14
WO2009028870A2 (en) 2009-03-05
WO2009028870A4 (en) 2009-06-04
JP5529021B2 (ja) 2014-06-25
EP2180896A4 (en) 2011-10-26
EP2180896B1 (en) 2013-04-24
WO2009028870A3 (en) 2009-04-23
CN101815522A (zh) 2010-08-25
CA2692232C (en) 2016-11-22
CA2692232A1 (en) 2009-03-05
US20130189189A1 (en) 2013-07-25
SG184701A1 (en) 2012-10-30
EP2180896A2 (en) 2010-05-05
AU2008293208A1 (en) 2009-03-05
JP2010537973A (ja) 2010-12-09
CN101815522B (zh) 2016-12-28
KR101039235B1 (ko) 2011-06-07
US20100143261A1 (en) 2010-06-10
KR20090023070A (ko) 2009-03-04
US8506948B2 (en) 2013-08-13

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