ES245955A1 - Procedimiento para la obtencion de aminas terciarias - Google Patents
Procedimiento para la obtencion de aminas terciariasInfo
- Publication number
- ES245955A1 ES245955A1 ES0245955A ES245955A ES245955A1 ES 245955 A1 ES245955 A1 ES 245955A1 ES 0245955 A ES0245955 A ES 0245955A ES 245955 A ES245955 A ES 245955A ES 245955 A1 ES245955 A1 ES 245955A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- reacting
- compound
- procedure
- tertiary amines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003512 tertiary amines Chemical class 0.000 title 1
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 6
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000002825 nitriles Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000005555 hypertensive agent Substances 0.000 abstract 1
- 230000001631 hypertensive effect Effects 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Procedimiento para la obtención de aminas terciarias de la fórmula general **(Ver fórmula)** donde Hal significa un resto halógeno **(Ver fórmula)** el anillo de pirrolidina o de piperidina e Y un resto alquilo recto o ramificado y sus compuestos amónicos cuaternarios caracterizado por hacerse reaccionar nitrilos de la fórmula general **(Ver fórmula)** con halogenuros halogenobencilmagnésicos de la fórmula general **(Ver fórmula)** o haciendo actuar sobre nitrilos de la fórmula general **(Ver fórmula)** halogenuros alquilmagnésicos de la fórmula general Y-Mg-Hal o aminarse por vía reductiva de manera en si conocida halógenobencilalquilcetonas de la fórmula general **(Ver fórmula)** con piperidina o pirrolidina en presencia de hidrógeno naciente o producido catalíticamente o de ácido fórmico y de sus derivados o por hacerse actuar sobre aminas primarias de la fórmula general **(Ver fórmula)** de manera en si conocida 1 4-dihalógenobutano y respectivamente 1 5-dihalógenopentano o por añadirse al compuesto olefínico doble de estiroles sustituídos de la fórmula general **(Ver fórmula)** pirrolidina o piperidina en presencia de un metal alcalino teniendo los restos **(Ver fórmula)** Hal e Y siempre los significados anteriormente indicados y transformarse eventualmente los productos obtenidos de manera en sí conocida en sus compuestos cuaternarios de amonio.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE851660X | 1958-01-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES245955A1 true ES245955A1 (es) | 1960-01-01 |
Family
ID=6781873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0245955A Expired ES245955A1 (es) | 1958-01-10 | 1958-12-15 | Procedimiento para la obtencion de aminas terciarias |
Country Status (2)
| Country | Link |
|---|---|
| ES (1) | ES245955A1 (es) |
| GB (1) | GB851660A (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL270984A (es) * | 1960-11-05 | |||
| US3261750A (en) * | 1962-10-12 | 1966-07-19 | Boehringer Sohn Ingelheim | Method of curbing appetite |
| US3261749A (en) * | 1962-10-12 | 1966-07-19 | Boehringer Sohn Ingelheim | Method of curbing appetite |
-
1958
- 1958-12-15 ES ES0245955A patent/ES245955A1/es not_active Expired
-
1959
- 1959-01-09 GB GB916/59A patent/GB851660A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB851660A (en) | 1960-10-19 |
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