ES2460965T5 - Utilización de un producto de aceite vegetal de girasol para tratar la piel - Google Patents

Utilización de un producto de aceite vegetal de girasol para tratar la piel Download PDF

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ES2460965T5
ES2460965T5 ES06013216.4T ES06013216T ES2460965T5 ES 2460965 T5 ES2460965 T5 ES 2460965T5 ES 06013216 T ES06013216 T ES 06013216T ES 2460965 T5 ES2460965 T5 ES 2460965T5
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lipids
cholesterol
cutaneous
vegetable oil
oil product
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ES2460965T3 (es
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Philippe Msika
Antoine Piccirilli
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Laboratoires Expanscience SA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/005—Preparations for sensitive skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/008—Preparations for oily skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Animal Husbandry (AREA)
  • Biophysics (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Fats And Perfumes (AREA)
  • Steroid Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Description

imagen1
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Por el contrario, éstas modifican de manera significativa la proporción de las distintas clases de los lípidos epidérmicos separados en cromatografía de capa fina en el totum.
Éstas disminuyen la neosíntesis de los tri-y di-glicéridos a favor de otros lípidos epidérmicos.
5 La composición 1.1 aumenta la neosíntesis del colesterol (sin modificación de la neosíntesis del sulfato de colesterol), y la neosíntesis de las ceramidas.
Las composiciones 1.2 y 1.3 aumentan la neosíntesis del sulfato de colesterol y del colesterol, y la neosíntesis de las 10 ceramidas.
La composición placebo no provoca aumento significativo de los distintos lípidos epidérmicos analizados.
3) Tablas de resultados 15

Tabla 3.1): Efecto de las composiciones 1.1, 1.2, 1.3 y placebo, así como del EGF y de una formulación cosmética que contiene ácido láctico, sobre la neosíntesis de los lípidos epidérmicos totales en discos de piel humana entera, después de 18 horas de incubación
Testigo
EGF 10 ng/ml Ácido láctico Comp. 1.2 Comp. 1.3 Comp. 1.1 Comp. placebo
4183,35
3104,63 1864,31 2479,26 3646,42 873,10 1506,12
4407,89
5043,66 4919,12 3858,70 5255,70 3726,00 4154,88
3691,69
3606,76 4027,67 6571,13 3900,53 3802,63 4429,96
1062,72
4565,02 1076,21 2457,78 3209,16 905,55 2373,94
3336,41
4080,02 2971,83 3841,72 4002,95 2326,82 3116,23
+/
+/
+/
+/
+/
+/
+/
1545,02
883,02 1800,62 1934,04 882,63 1660,22 1408,09
100
122 89 115 120 70 93
20 Los resultados se expresan en cpm/mg de epidermis. En negrita: media y desviación típica En itálica: porcentaje del grupo testigo *: media significativamente diferente del grupo testigo (p<0,05)
25
Tabla 3.2): Efecto de las composiciones 1.2 y 1.3, así como del EGF y de una formulación cosmética que contiene ácido láctico, sobre la neosíntesis de los lípidos polares, del sulfato de colesterol, de los cerebrósidos, de las ceramidas 1 y 2, del colesterol y de los tri-+ di-glicéridos en discos de piel humana entera, después de 18 horas de incubación
30
Producto
Lípidos polares Sulfato de colesterol Cerebrósidos Ceramida 1 Ceramida 2 Colesterol Tri-+ digliceridos
Testigo
28,94 24,96 31,74 42,90 32,14 +/7,70 100 6,04 4,80 6,26 5,12 5,56 +/0,71 100 1,89 2,08 4,02 4,44 3,11 +/1,31 100 2,03 2,67 2,71 1,67 2,27 +/0,51 100 2,03 2,07 2,15 1,47 1,93 +/0,31 100 5,23 5,04 7,89 5,61 6,69 +/1,60 100 50,83 53,76 45,23 38,84 47,17 +/6,58 100
EGF 10 ng/ml
57,27 34,42 27,69 33,53 38,23 +/13,04 119 2,31 3,69 3,44 2,57 3,00* +/0,67 54 2,87 3,82 4,77 4,02 3,87 +/0,78 125 2,02 1,41 3,41 4,02 2,72 +/1,21 120 3,81 2,38 2,74 3,05 3,00* +/0,61 155 7,07 9,46 7,86 9,99 8,60 +/1,36 128 42,67 44,82 50,08 42,83 45,10 +/3,46 96
Ácido láctico
49,20 33,04 64,49 53,51 50,06 +/13,05 4,07 4,16 5,90 4,25 4,60 +/0,87 4,46 4,54 6,07 4,68 4,94* +/0,76 2,37 2,64 2,94 2,58 2,63 +/0,24 1,70 3,32 2,57 1,44 2,26 +/0,86 7,77 9,72 8,07 8,67 8,56 +/0,86 33,43 42,58 31,95 24,86 33,21 +/7,28
10
Producto
Lípidos polares Sulfato de colesterol Cerebrósidos Ceramida 1 Ceramida 2 Colesterol Tri-+ digliceridos
156
83 159 116 117 128 70
Composición 1.2
24,57 28,71 33,09 35,78 30,54 +/4,93 95 6,89 8,34 6,86 7,35 7,36* +/0,69 132 4,41 5,91 4,02 7,76 5,53 +/1,70 178 2,78 5,94 4,55 9,20 5,62* +/2,72 247 6,86 3,34 4,79 4,37 4,84* +/1,48 251 44,35 35,04 36,97 34,01 37,59* +/4,67 562 10,13 12,72 9,72 11,52 11,02* +/1,37 23
Composición 1.3
38,88 43,70 37,70 47,94 42,06 +/4,70 131 6,23 8,25 6,88 6,15 6,88* +/0,97 124 6,23 4,55 3,97 6,13 5,22 +/1,13 168 3,20 3,51 3,52 4,24 3,62* +/0,44 159 8,92 7,25 6,69 5,40 7,07* +/1,46 366 28,63 24,34 33,55 24,30 27,71* +/4,39 414 7,92 8,41 7,68 5,85 7,47* +/1,12 16
Los resultados se expresan en porcentaje de lípidos totales radiomarcados depositados sobre la CCM. En negrita: media y desviación típica En itálica: porcentaje del grupo testigo
5 *: media significativamente diferente del grupo testigo (p<0,05)
Tabla 3.3): Efecto de las composiciones 1.1 y placebo sobre la neosíntesis de los lípidos polares, del sulfato de colesterol, de los cerebrósidos, de las ceramidas 1 y 2, del colesterol y de los tri-+ di-glicéridos en discos de piel humana entera, después de 18 horas de incubación
10
Producto
Lípidos polares Sulfato de colesterol Cerebrósidos Ceramida 1 Ceramida 2 Colesterol Tri-+ diglicéridos
Testigo
28,94 24,96 31,74 42,90 32,14 +/7,70 100 6,04 4,80 6,26 5,12 5,56 +/0,71 100 1,89 2,08 4,02 4,44 3,11 +/1,31 100 2,03 2,67 2,71 1,67 2,27 +/0,51 100 2,03 2,07 2,15 1,47 1,93 +/0,31 100 8,23 5,04 7,89 5,61 6,69 +/1,60 100 50,83 53,76 45,23 38,84 47,17 +/6,58 100
Composición 1.1
37,24 32,48 31,92 25,87 31,88 +/4,66 99 6,43 4,83 3,81 4,41 4,87 +/1,12 88 4,35 5,45 5,68 4,49 4,99 +/0,67 161 5,12 4,22 5,43 5,75 5,13* +/0,66 226 8,38 7,77 8,06 11,37 8,90* +/1,67 461 32,19 32,51 32,23 38,00 33,73* +/2,85 504 16,28 12,74 10,86 10,11 12,50* +/2,75 26
Composición placebo
73,67 58,70 55,90 63,39 62,92 +/7,81 196 9,27 11,03 6,63 5,69 8,16 +/2,44 147 7,69 7,60 3,71 4,48 5,87 +/2,07 189 2,44 2,51 4,21 4,17 3,33 +0,99 147 2,05 3,39 3,67 3,35 3,12 +/0,72 161 3,03 3,71 8,66 4,93 5,08 +/2,51 76 18,60 13,07 17,20 27,98 19,21* +/6,30 41
Los resultados se expresan en porcentaje de lípidos totales radiomarcados depositados sobre la CCM. En negrita: media y desviación típica En itálica: porcentaje del grupo testigo
15 *: media significativamente diferente del grupo testigo (p<0,05)
11
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Claims (1)

  1. imagen1
ES06013216.4T 1999-09-22 2000-09-20 Utilización de un producto de aceite vegetal de girasol para tratar la piel Expired - Lifetime ES2460965T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9911844 1999-09-22
FR9911844A FR2798591B1 (fr) 1999-09-22 1999-09-22 Utilisation d'un produit d'huile vegetale pour augmenter la synthese des lipides cutanes en cosmetique, pharmacie ou dermatologie et en tant qu'additif alimentaire

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Publication Number Publication Date
ES2460965T3 ES2460965T3 (es) 2014-05-16
ES2460965T5 true ES2460965T5 (es) 2017-11-27

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ES00964325T Expired - Lifetime ES2269180T3 (es) 1999-09-22 2000-09-20 Utilizacion de un producto de aceite vegetal como agente para aumentar la sintesis de los lipidos cutaneos.
ES06013216.4T Expired - Lifetime ES2460965T5 (es) 1999-09-22 2000-09-20 Utilización de un producto de aceite vegetal de girasol para tratar la piel

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US (2) US8147883B1 (es)
EP (2) EP1214051B1 (es)
KR (1) KR100623466B1 (es)
AT (1) ATE334653T1 (es)
DE (1) DE60029801T2 (es)
ES (2) ES2269180T3 (es)
FR (1) FR2798591B1 (es)
TW (1) TWI238724B (es)
WO (1) WO2001021150A1 (es)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004008440A1 (de) * 2004-02-19 2005-09-22 Stockhausen Gmbh Kosmetisches und/oder dermatologisches Mittel zur Steigerung des endogenen Lipidgehaltes der Haut
FR2869541B1 (fr) 2004-04-30 2007-12-28 Expanscience Sa Lab Utilisation d'une composition comprenant du d-mannoheptulose et/ou du perseitol dans le traitement et la prevention des maladies liees a une modification de l'immunite innee
FR2869543B1 (fr) 2004-04-30 2006-07-28 Expanscience Laboratoires Sa Medicament comprenant un extrait peptidique d'avocat destine au traitement et la prevention des maladies liees a une deficience du systeme immunitaire
US9089576B2 (en) 2004-04-30 2015-07-28 Laboratoires Expanscience Medicament comprising a peptide extract of avocado, which is intended for the treatment and prevention of illnesses that are linked to an immune system deficiency or oxidative stress or skin ageing or dry skin
WO2006040349A1 (en) * 2004-10-14 2006-04-20 Symrise Gmbh & Co. Kg Process for strengthening the barrier function of undamaged skin
FR2910815B1 (fr) 2006-12-28 2010-10-29 Expanscience Lab Composition comprenant un extrait de graines de quinoa
EP2036535A1 (en) * 2007-09-07 2009-03-18 Beauté Pacifique ApS Vitamin containing cream
EP2340089A2 (en) * 2008-09-08 2011-07-06 Polyol Biotech Ltd. Cosmetic compositions comprising polyhydroxylated fatty alcohols and derivatives and uses thereof
US20110217251A1 (en) * 2008-09-08 2011-09-08 Shai Meretzki Therapeutic compositions comprising polyhydroxyltate fatty alcohol derivatives and uses thereof
FR2938193B1 (fr) 2008-11-07 2011-08-12 Expanscience Lab Medicament ou composition dermatologique comprenant un extrait peptidique d'avocat destine au traitement et a la prevention du prupit
FR2940291B1 (fr) 2008-12-23 2012-12-21 Isp Investments Inc Peptide derive d'hmg-coa reductase et composition cosmetique ou pharmaceutique le contenant
FR2940292B1 (fr) 2008-12-23 2013-05-10 Isp Investments Inc Peptides derives d'hmg-coa reductase et composition cosmetique et/ou pharmaceutique les contenant
FR2940126B1 (fr) 2008-12-23 2013-05-10 Isp Investments Inc Composition cosmetique ou pharmaceutique apaisante comprenant un peptide activateur de la hmg-coa reductase
FR2940125B1 (fr) 2008-12-23 2013-03-22 Isp Investments Inc Composition cosmetique ou pharmaceutique apaisante comprenant un peptide activateur de la hmg-coa reductase
FR2944445B1 (fr) 2009-04-15 2013-08-16 Isp Investments Inc Composition cosmetique et/ou pharmaceutique comprenant un hydrolysat peptidique apaisant
US8933036B2 (en) 2009-04-15 2015-01-13 Isp Investments Inc. Cosmetic and/or pharmaceutical composition comprising a yeast peptide hydrolysate and use of the yeast peptide hydrolysate as an active agent for strengthening hair
FR2944526B1 (fr) 2009-04-15 2013-05-10 Isp Investments Inc Composition cosmetique et/ou pharmaceutique comprenant un hydrolysat peptidique capable de renforcer la fonction barriere
FR2948565B1 (fr) 2009-07-30 2011-10-28 Expanscience Lab Composition cosmetique pour le traitement de l'acne comprenant un extrait petidique de schizandra
FR2948566B1 (fr) 2009-07-30 2012-08-10 Expanscience Lab Extrait du fruit de schizandra sphenanthera et compositions cosmetiques, dermatologiques et nutraceutiques le comprenant
FR2949044B1 (fr) 2009-08-12 2021-05-07 Expanscience Lab Composition comprenant une fraction d'insaponifiable
KR101693694B1 (ko) * 2009-08-31 2017-01-09 (주)아모레퍼시픽 옹기중탕을 이용한 약재의 피부재생효능 증진방법
FR2953135B1 (fr) 2009-11-30 2012-05-11 Expanscience Lab Extrait de graines d'acacia macrostachya et compositions cosmetiques, pharmaceutiques, dermatologiques, nutraceutiques ou alimentaires le comprenant
FR2953136B1 (fr) 2009-11-30 2012-05-11 Expanscience Lab Extrait de graines de vigna unguiculata et compositions cosmetiques, pharmaceutiques, dermatologiques, nutraceutiques ou alimentaires le comprenant
FR2953722B1 (fr) 2009-12-16 2012-03-09 Expanscience Lab Composition comprenant au moins un sucre en c7 pour le traitement de l'alopecie, pour le traitement cosmetique des phaneres, et pour le soin des cheveux, cils ou ongles
FR2969495B1 (fr) 2010-12-22 2013-10-11 Expanscience Lab Extrait de parties aeriennes de maca riche en polyphenols et composition le comprenant
FR2969496B1 (fr) 2010-12-22 2013-11-08 Expanscience Lab Extrait de pulpe et/ou de peau d'avocat riche en polyphenols et compositions cosmetiques, dermatologiques et nutraceutiques le comprenant
FR2975004B1 (fr) 2011-05-13 2013-06-28 Expanscience Lab Nouvel actif anti-rougeurs et compositions cosmetiques le comprenant
FR2978661B1 (fr) * 2011-08-03 2017-12-22 Beaute Luxe Simplicite Composition lipidique pour application cosmetique
FR2994386B1 (fr) * 2012-08-07 2016-06-24 Thorel Jean-Noel Inhibition de l'adhesion de micro-organismes pathogenes par un ester de saccharose et/ou de sorbitan dans le traitement cosmetique de l'atopie cutanee
FR2999429B1 (fr) 2012-12-18 2015-01-02 Expanscience Lab Extrait de graines de passiflore et compositions cosmetiques, pharmaceutiques, dermatologiques ou nutraceutiques le comprenant
FR3001889B1 (fr) 2013-02-11 2021-02-12 Expanscience Lab Utilisation d'une composition comprenant un perseose d'avocat dans la protection des cellules souches epidermiques .
WO2014178427A1 (ja) * 2013-05-02 2014-11-06 学校法人順天堂 セマフォリン３ａの発現調節法
FR3011008B1 (fr) 2013-09-24 2017-12-29 Expanscience Lab Procedes d'evaluation des effets deleteres des uv sur la peau d'enfant
FR3010906B1 (fr) 2013-09-25 2016-12-23 Expanscience Lab Extrait lipidique de graines de passiflores
FR3016373B1 (fr) 2014-01-10 2018-01-19 Laboratoires Expanscience Modele de peau de mammelon reconstitue
FR3028764B1 (fr) 2014-11-26 2016-12-09 Expanscience Lab Extrait peptidique et osidique de fruit de schizandra et amelioration de la reponse du systeme neurosensoriel cutane
US10137073B2 (en) 2016-01-02 2018-11-27 L'oreal Cosmetic compositions comprising ceramides and cholesterol
FR3082122B1 (fr) 2018-06-11 2021-01-01 Basf Beauty Care Solutions France Sas Utilisation d'un extrait de bixa orellana
CN109157434A (zh) * 2018-08-28 2019-01-08 深圳市前海荣格生物技术（集团）有限公司 一种止痒保湿浴后乳液及其制备方法
US11433016B2 (en) * 2019-03-28 2022-09-06 L'oreal Cosmetic compositions for skin
US11642300B2 (en) 2019-05-15 2023-05-09 Johnson & Johnson Consumer Inc. Method of selecting skin treatment regimens, ingredients and compositions
FR3098405B1 (fr) 2019-07-12 2021-06-25 Expanscience Lab Composition comprenant des polyphénols de graines de passiflore, des peptides d’avocat et un extrait d’hamamélis et utilisation pour traiter et/ou prévenir les vergetures
MX2022007079A (es) 2019-12-16 2022-07-11 Colgate Palmolive Co Composiciones para el cuidado personal y metodos para estas.
MX2022007109A (es) * 2019-12-16 2022-07-11 Colgate Palmolive Co Composiciones para el cuidado personal y metodos para estas.
EP4017470A1 (en) 2019-12-16 2022-06-29 Colgate-Palmolive Company Personal care compositions and methods for the same
US20220142560A1 (en) 2020-11-06 2022-05-12 Johnson & Johnson Consumer Inc. Microbiome and metobolome clusters to evaluate skin health
CA3249846A1 (en) 2022-01-28 2023-08-03 Kenvue Brands Llc Predictive Biomarkers for Atopic Dermatitis
KR20250025597A (ko) 2022-04-04 2025-02-24 존슨 앤드 존슨 컨수머 인코포레이티드 아토피성 피부염의 발병을 예방하거나 아토피성 피부염을 치료하기 위한 기회의 창 피부 치료 요법 및 조성물
FR3143977A1 (fr) * 2022-12-21 2024-06-28 Laboratoires Expanscience Insaponifiables d'avocat-malassezia
FR3148364A1 (fr) 2023-05-05 2024-11-08 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic Composition pharmaceutique ou cosmétique favorisant la diminution de la production du sébum au niveau du cuir chevelu
WO2025003996A1 (en) * 2023-06-28 2025-01-02 Kenvue Brands Llc Methods of using a skincare composition
WO2025003994A1 (en) * 2023-06-28 2025-01-02 Kenvue Brands Llc Skincare composition and methods of manufacturing same
CN119896674A (zh) * 2023-10-27 2025-04-29 上海交通大学医学院附属新华医院 胆固醇硫酸酯在制备治疗特应性皮炎的药物中的应用

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2041594A5 (es) * 1969-04-30 1971-01-29 Expanscience
FR2187328A1 (en) * 1972-06-13 1974-01-18 Froment Pier E De Non-saponified lucerne extract - useful in dermatology cosmetology and as aid to cicatrisation
US3993756A (en) * 1973-05-09 1976-11-23 Takashi Kaneda Antilipemic agent containing a soybean oil fraction
FR2405068A1 (fr) * 1977-10-10 1979-05-04 Sauba Lab Composition pharmaceutique destinee au traitement du dessechement cutane
FR2443835A1 (fr) * 1979-10-09 1980-07-11 Courtin Jacques Creme pour les mains
FR2471775A1 (fr) * 1979-12-18 1981-06-26 Oreal Nouvelle huile cosmetique, et compositions la contenant
FR2488507A2 (fr) † 1980-08-13 1982-02-19 Oreal Nouvelle huile cosmetique contenant des fractions insaponifiables ajoutees, et compositions cosmetiques la contenant
US4324802A (en) * 1979-12-18 1982-04-13 L'oreal Cosmetic oil and composition containing the same
JPS57131716A (en) * 1981-01-28 1982-08-14 Hiroshi Sekimoto Cosmetic for exclusive use to plantar skin
US4454159A (en) * 1981-12-28 1984-06-12 Albert Musher Dermatological treatment preparations
FR2648347B1 (fr) * 1989-06-15 1994-04-29 Sederma Sa Preparations cosmetiques possedant des proprietes adoucissantes
FR2653974B1 (fr) * 1989-11-03 1992-12-31 Expanchimie Sarl Additif alimentaire constitue d'extraits de soja et/ou d'avocat.
FR2669239B1 (fr) 1990-11-21 1993-06-18 Electricite De France Appareil de distillation moleculaire a chauffage par induction.
ATE142883T1 (de) 1991-03-28 1996-10-15 Rooperol Na Nv Zusammensetzungen von phytosterolen mit phytosterolinen als immunmodulatoren
FR2678632B1 (fr) 1991-07-03 1994-09-02 Pharmascience Lab Procede de preparation de l'insaponifiable d'avocat permettant d'ameliorer sa teneur en l'une de ses fractions dite h.
JPH05279242A (ja) * 1992-02-05 1993-10-26 Otsuka Pharmaceut Factory Inc 浴用液剤
FR2692783B1 (fr) * 1992-06-25 1995-05-05 Expanchimie Compositions à base de fractions insaponifiables d'huiles de germe de blé et de sésame, et leurs utilisations notamment en cosmétologie et en qualité de complément alimentaire.
FR2694692B1 (fr) * 1992-08-13 1994-10-28 Thorel Jean Noel Préparation cosmétique de nutrition de la peau.
FR2702773B1 (fr) * 1993-03-19 1995-06-16 Deslog Procede de preparation de fractions de matieres grasses d'origine vegetale enrichies en matieres insaponifiables.
FR2710264B1 (fr) * 1993-09-21 1995-12-08 Rocher Yves Biolog Vegetale Utilisation pour le traitement des peaux mixtes d'une quantité efficace de substances actives.
US5468490A (en) 1993-10-25 1995-11-21 Conkle & Olesten Lipidic furans useful for skin therapeutics
FR2724663B1 (fr) * 1994-09-20 1997-01-24 Fabre Pierre Dermo Cosmetique Huile d'argan enrichie, procede de preparation et composition cosmetique la comprenant
US5928659A (en) * 1996-06-07 1999-07-27 Moy; Lawrence S. Cosmetic formulation and method for amelioration of skin keratoses and striae distensae
DE19631792A1 (de) * 1996-08-08 1997-03-20 Henkel Kgaa Sonnenschutzmittel
DE19634959A1 (de) 1996-08-29 1998-03-05 Karl Aulbach Wund- und Heilsalbe
JP3169121B2 (ja) * 1996-11-11 2001-05-21 ティーディーケイ株式会社 テープカセット
DE19652522C2 (de) * 1996-12-17 2000-10-26 Cognis Deutschland Gmbh Verfahren zur Gewinnung von Tocopherolen und/oder Sterinen
FR2762512B1 (fr) * 1997-04-24 2000-10-13 Pharmascience Lab Compositions a base d'huile de lupin, notamment a base d'huile de lupin et d'huile de germe de ble et leur utilisation en cosmetologie, en pharmacie et en tant que complement alimentaire
RO113113B1 (ro) 1997-05-07 1999-04-30 Felician Titus Stoica Unguent pentru tratamentul arsurilor si al altor afectiuni ale pielii
DE19744703C1 (de) * 1997-10-10 1999-02-11 Henkel Kgaa Verwendung von Phytosterolestern als Rückfettungsmittel
FR2778181B1 (fr) * 1998-04-29 2002-05-03 Pharmascience Lab Nouveaux composes extraits d'huile vegetale utilisables dans l'industrie pharmaceutique et cosmetique,notamment pour l'inhibition de la croissance cellulaire
IT1299264B1 (it) * 1998-05-15 2000-02-29 Codex V S R L Composizioni farmaceutiche topiche utili per il trattamento di patologie cutanee su base infiammatoria, immunitaria o proliferativa
FR2798667B1 (fr) 1999-09-22 2001-12-21 Pharmascience Lab Procede d'extraction des composes furaniques et alcools gras polyhydroxyles de l'avocat, composition a base de et utilisation de ces composes en therapeutique, cosmetique et alimentaire

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EP1707189B1 (fr) 2014-03-12
US8147883B1 (en) 2012-04-03
HK1095283A1 (en) 2007-05-04
FR2798591B1 (fr) 2001-10-26
US8053003B2 (en) 2011-11-08
DE60029801T2 (de) 2007-10-18
DE60029801D1 (de) 2006-09-14
KR20020047180A (ko) 2002-06-21
US20090286871A1 (en) 2009-11-19
ES2269180T3 (es) 2007-04-01
EP1214051B1 (fr) 2006-08-02
ES2460965T3 (es) 2014-05-16
TWI238724B (en) 2005-09-01
ATE334653T1 (de) 2006-08-15
WO2001021150A1 (fr) 2001-03-29
EP1707189B2 (fr) 2017-07-26
FR2798591A1 (fr) 2001-03-23
KR100623466B1 (ko) 2006-09-18
EP1214051A1 (fr) 2002-06-19
EP1707189A2 (fr) 2006-10-04

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