ES2490965T3 - Procedimiento para la operación de una celda de trabajo para muestras automatizadas - Google Patents

Procedimiento para la operación de una celda de trabajo para muestras automatizadas Download PDF

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Publication number
ES2490965T3
ES2490965T3 ES11164310.2T ES11164310T ES2490965T3 ES 2490965 T3 ES2490965 T3 ES 2490965T3 ES 11164310 T ES11164310 T ES 11164310T ES 2490965 T3 ES2490965 T3 ES 2490965T3
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sample
work cell
automated
biological
test order
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Joerg Haechler
Frederic Furrer
Andrzej Knafel
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F Hoffmann La Roche AG
Roche Diagnostics GmbH
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F Hoffmann La Roche AG
Roche Diagnostics GmbH
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00871—Communications between instruments or with remote terminals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G01N35/0095—Scheduling introducing urgent samples with priority, e.g. Short Turn Around Time Samples [STATS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/143—Quality control, feedback systems
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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    • B01L2300/021—Identification, e.g. bar codes
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    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5082—Test tubes per se
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B13/00—Control arrangements specially designed for centrifuges; Program control of centrifuges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/04—Periodical feeding or discharging; Control arrangements therefor
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    • G01N2035/00495—Centrifuges
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    • G01N35/00722—Communications; Identification
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    • G01N2035/00752—Type of codes bar codes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00821—Identification of carriers, materials or components in automatic analysers nature of coded information
    • G01N2035/00851—Identification of carriers, materials or components in automatic analysers nature of coded information process control parameters
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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    • G01N2035/00891—Displaying information to the operator
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G—PHYSICS
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    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0403—Sample carriers with closing or sealing means
    • G01N2035/0405—Sample carriers with closing or sealing means manipulating closing or opening means, e.g. stoppers, screw caps, lids or covers
    • G—PHYSICS
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    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
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    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0406—Individual bottles or tubes
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    • G01N35/04—Details of the conveyor system
    • G01N2035/046—General conveyor features
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    • G—PHYSICS
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    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
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    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
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    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
    • Y10T436/114165—Automated chemical analysis with conveyance of sample along a test line in a container or rack with step of insertion or removal from test line

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  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Primary Health Care (AREA)
  • Medical Informatics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Un procedimiento para la operación de una celda de trabajo para muestras automatizada (102, 410, 301) para el procesamiento de una o más muestras biológicas (125-130), en que la celda de trabajo comprende una estación de entrada de muestras (108, 401) y el procedimiento comprende: - la recepción (201) de las una o más muestras biológicas por la estación de entrada de muestras, en que cada muestra está contenida en un tubo de muestras y cada tubo de muestras es de un tipo (122-124); - la determinación por la celda de trabajo para muestras automatizada de si se ha recibido o no una orden de prueba (104) para al menos una de dichas muestras biológicas y, en caso de que se haya recibido una orden de prueba (104) para al menos una de dichas muestras biológicas, en que la orden de prueba es un objeto de datos que indica una o más pruebas analíticas que han de ejecutarse en la al menos una muestra biológica y que indica una o más primeras etapas de procesamiento, la ejecución automática (204) por la celda de trabajo para muestras automatizada de las una o más primeras etapas de procesamiento en la al menos una muestra biológica, caracterizado por - la determinación (205) por la celda de trabajo para muestras automatizada, en caso de que no se haya recibido dicha orden de prueba, de una o más segundas etapas de procesamiento en función del tipo del tubo de muestras que contiene dicha al menos una muestra biológica y la ejecución por parte de la celda de trabajo para muestras automatizada (206) de dichas una o más segundas etapas de procesamiento en la al menos una muestra biológica

Description

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E11164310
07-08-2014
Apéndice
Tabla 1: tipos de tubos
Tipo de tubo
Sustancias añadidas Tipo de muestra Posibles análisis (indicados en la orden de prueba)
I
Contiene un activador de coagulación El activador de coagulación acelera la coagulación muestra de suero Química clínica en suero (determinación del nivel de glucosa/iones/proteínas etc.); inmunología; análisis rutinario de donantes de sangre; pruebas diagnósticas de enfermedades infecciosas
II
Contiene un activador de coagulación y un gel La densidad del gel está entre la densidad del suero sanguíneo y la de las células sanguíneas. El gel impide el intercambio de sustancias entre las células sanguíneas y el suero muestra de suero Química clínica en suero (determinación del nivel de glucosa/iones/proteínas etc.); inmunología; análisis rutinario de donantes de sangre; pruebas diagnósticas de enfermedades infecciosas
III
Contiene el anticoagulante EDTA K2-EDTA no deforma las células sanguíneas y por tanto es el anticoagulante preferido para análisis hematológicos muestras hematológicas (sangre entera) Exámenes hematológicos clínicos de células sanguíneas; análisis rutinarios de donantes de sangre
IV
Contiene anticoagulantes: heparina de litio, heparina de sodio y gel La densidad del gel está entre la densidad del plasma sanguíneo y la de las células sanguíneas. El gel impide el intercambio de sustancias entre las células sanguíneas y el plasma muestra de plasma Química clínica en plasma (determinación del nivel de glucosa/iones/proteínas etc.); inmunología; análisis rutinario de donantes de sangre; pruebas diagnósticas de enfermedades infecciosas; algunos aspectos de hemorreología
V
Contiene trombina, un activador rápido de la coagulación muestra de suero STAT Análisis rápidos de suero STAT
VI
Contiene el anticoagulante citrato El citrato se une al calcio de la muestra de sangre muestra de plasma con citrato Análisis de coagulación: la adición de calcio permite a la sangre coagular de nuevo; determinación, por ejemplo, del tiempo de coagulación; ensayos de funcionalidad plaquetaria
VII
Tubos de orina muestra de orina Análisis químico en muestras de orina
17

Claims (1)

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ES11164310.2T 2011-04-29 2011-04-29 Procedimiento para la operación de una celda de trabajo para muestras automatizadas Active ES2490965T3 (es)

Applications Claiming Priority (1)

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EP11164310.2A EP2518514B1 (en) 2011-04-29 2011-04-29 A method for operating an automated sample workcell

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ES2490965T3 true ES2490965T3 (es) 2014-09-04

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EP (1) EP2518514B1 (es)
JP (1) JP6018406B2 (es)
CN (1) CN102759630B (es)
AU (1) AU2012202369B2 (es)
ES (1) ES2490965T3 (es)

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