ES2502472T3 - Composición adhesiva para su uso en un inmunosensor - Google Patents

Composición adhesiva para su uso en un inmunosensor Download PDF

Info

Publication number
ES2502472T3
ES2502472T3 ES12162722.8T ES12162722T ES2502472T3 ES 2502472 T3 ES2502472 T3 ES 2502472T3 ES 12162722 T ES12162722 T ES 12162722T ES 2502472 T3 ES2502472 T3 ES 2502472T3
Authority
ES
Spain
Prior art keywords
immunosensor
adhesive composition
adhesive
composition
poloxamer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12162722.8T
Other languages
English (en)
Inventor
Roland C. Chatelier
Dennis Rylatt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cilag GmbH International
Original Assignee
Cilag GmbH International
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cilag GmbH International filed Critical Cilag GmbH International
Application granted granted Critical
Publication of ES2502472T3 publication Critical patent/ES2502472T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438Electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

El uso de una composición adhesiva en un inmunosensor, dicha composición comprendiendo: un adhesivo; agua; un poloxámero; y un anticoagulante.

Description

imagen1
imagen2
imagen3
imagen4
imagen5
imagen6
imagen7
imagen8
imagen9

Claims (1)

  1. imagen1
ES12162722.8T 2009-09-30 2010-09-29 Composición adhesiva para su uso en un inmunosensor Active ES2502472T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US570268 1990-08-17
US12/570,268 US8221994B2 (en) 2009-09-30 2009-09-30 Adhesive composition for use in an immunosensor

Publications (1)

Publication Number Publication Date
ES2502472T3 true ES2502472T3 (es) 2014-10-03

Family

ID=43333307

Family Applications (2)

Application Number Title Priority Date Filing Date
ES10251678T Active ES2391938T3 (es) 2009-09-30 2010-09-29 Composición adhesiva para su uso en un inmunosensor
ES12162722.8T Active ES2502472T3 (es) 2009-09-30 2010-09-29 Composición adhesiva para su uso en un inmunosensor

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES10251678T Active ES2391938T3 (es) 2009-09-30 2010-09-29 Composición adhesiva para su uso en un inmunosensor

Country Status (11)

Country Link
US (3) US8221994B2 (es)
EP (2) EP2472261B1 (es)
JP (1) JP5048114B2 (es)
KR (1) KR101233740B1 (es)
CN (1) CN102033123B (es)
AU (1) AU2010210002B2 (es)
CA (2) CA2964540C (es)
ES (2) ES2391938T3 (es)
IL (1) IL207541A0 (es)
SG (1) SG169968A1 (es)
TW (1) TWI516288B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8221994B2 (en) * 2009-09-30 2012-07-17 Cilag Gmbh International Adhesive composition for use in an immunosensor
US8877034B2 (en) * 2009-12-30 2014-11-04 Lifescan, Inc. Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity
US8101065B2 (en) * 2009-12-30 2012-01-24 Lifescan, Inc. Systems, devices, and methods for improving accuracy of biosensors using fill time
US8932445B2 (en) 2010-09-30 2015-01-13 Cilag Gmbh International Systems and methods for improved stability of electrochemical sensors
US8617370B2 (en) 2010-09-30 2013-12-31 Cilag Gmbh International Systems and methods of discriminating between a control sample and a test fluid using capacitance
CA2823180C (en) * 2010-12-31 2018-10-23 Ronald C. Chatelier Systems and methods for high accuracy analyte measurement
EP2893334A1 (en) 2012-09-07 2015-07-15 Cilag GmbH International Electrochemical sensors and a method for their manufacture
JP6560197B2 (ja) * 2013-06-10 2019-08-14 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 試験要素を産生するための方法およびデバイス
US20150096906A1 (en) 2013-10-07 2015-04-09 Cilag Gmbh International Biosensor with bypass electrodes
US20150144507A1 (en) 2013-11-22 2015-05-28 Cilag Gmbh International Folded biosensor
EP4043879A1 (en) 2014-09-26 2022-08-17 Abbott Point Of Care Inc Single channel cartridge device for coagulation assays in fluid samples
US10048281B2 (en) 2014-09-26 2018-08-14 Abbott Point Of Care Inc. Cartridge device with segmented fluidics for assaying coagulation in fluid samples
EP3198272B1 (en) 2014-09-26 2022-04-06 Abbott Point Of Care, Inc. Cartridge device identification for coagulation assays in fluid samples
US10048282B2 (en) 2014-09-26 2018-08-14 Abbott Point Of Care Inc. Cartridge device with fluidic junctions for coagulation assays in fluid samples
EP3198281B1 (en) 2014-09-26 2023-01-25 Abbott Point Of Care, Inc. Ellagic acid formulations for use in coagulation assays
EP3955003B1 (en) 2014-09-26 2023-06-21 Abbott Point Of Care Inc Sensors for assaying coagulation in fluid samples
WO2016049515A1 (en) 2014-09-26 2016-03-31 Abbott Point Of Care Inc. Microfabricated device with micro-environment sensors for assaying coagulation in fluid samples
US9974471B1 (en) * 2014-10-24 2018-05-22 Verily Life Sciences Llc Analyte detection system and method for intradermal implantation of biocompatible optode nanosensors
JP6609001B2 (ja) * 2018-06-04 2019-11-20 シラグ・ゲーエムベーハー・インターナショナル 高精度分析物測定用システム及び方法
EP3640344B1 (en) * 2018-10-03 2024-03-13 ARKRAY, Inc. Direct electron transfer-type oxidoreductase-modified molecular recognition element
CN209829010U (zh) * 2019-03-01 2019-12-24 南京岚煜生物科技有限公司 一种多通道微流体凝血检测芯片

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50759B1 (es) * 1969-03-20 1975-01-11
US3692733A (en) * 1971-03-08 1972-09-19 Cpc International Inc Resin coated sand
JPS5321244A (en) * 1976-08-10 1978-02-27 Kuraray Co Ltd Construction sheet material having tenacity
GB8629231D0 (en) * 1986-12-06 1987-01-14 Smith & Nephew Ass Adhesive & dressings
US5656286A (en) 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
DE3924393A1 (de) * 1989-07-24 1991-01-31 Roehm Gmbh Wasserloeslicher druckempfindlicher hauthaftkleber, dessen verwendung und damit ausgeruestete mittel
US5276079A (en) 1991-11-15 1994-01-04 Minnesota Mining And Manufacturing Company Pressure-sensitive poly(n-vinyl lactam) adhesive composition and method for producing and using same
US5705551A (en) * 1991-12-06 1998-01-06 Avery Dennison Corporation Elastomeric pressure-sensitive adhesive compositions exhibiting good cutting performance
US5773490A (en) * 1993-06-24 1998-06-30 Takiron Co., Ltd. Pressure sensitive adhesive for transdermal absorption formulations
IL113583A (en) * 1994-05-26 1999-12-22 Rohm & Haas Acrylic pressure sensitive adhesive
US6638415B1 (en) * 1995-11-16 2003-10-28 Lifescan, Inc. Antioxidant sensor
US6174420B1 (en) * 1996-11-15 2001-01-16 Usf Filtration And Separations Group, Inc. Electrochemical cell
US6521110B1 (en) * 1995-11-16 2003-02-18 Lifescan, Inc. Electrochemical cell
AUPN661995A0 (en) * 1995-11-16 1995-12-07 Memtec America Corporation Electrochemical cell 2
US5885678A (en) * 1996-06-03 1999-03-23 Xerox Corporation Coated labels
US6632349B1 (en) * 1996-11-15 2003-10-14 Lifescan, Inc. Hemoglobin sensor
AUPO581397A0 (en) * 1997-03-21 1997-04-17 Memtec America Corporation Sensor connection means
US5969003A (en) * 1998-02-02 1999-10-19 Xerox Corporation Ink compositions
US6475360B1 (en) * 1998-03-12 2002-11-05 Lifescan, Inc. Heated electrochemical cell
US6312715B1 (en) * 1998-05-01 2001-11-06 3M Innovative Properties Company Adhesive microsphere drug delivery composition
US6565738B1 (en) * 1999-01-28 2003-05-20 Abbott Laboratories Diagnostic test for the measurement of analyte in abiological fluid
DE19912365A1 (de) * 1999-03-19 2000-09-21 Roche Diagnostics Gmbh Mehrschichtiges analytisches Hilfsmittel
DE19918106A1 (de) * 1999-04-22 2000-10-26 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern
US6232366B1 (en) 1999-06-09 2001-05-15 3M Innovative Properties Company Pressure sensitive conductive adhesive having hot-melt properties and biomedical electrodes using same
JP4503897B2 (ja) * 1999-07-07 2010-07-14 スリーエム イノベイティブ プロパティズ カンパニー 流体制御フィルムを有する検出物品
US6342561B1 (en) * 1999-11-17 2002-01-29 3M Innovative Properties Company Organic particulate-filled adhesive
US6571651B1 (en) * 2000-03-27 2003-06-03 Lifescan, Inc. Method of preventing short sampling of a capillary or wicking fill device
JP4323797B2 (ja) * 2000-07-07 2009-09-02 エイ.ブイ.トップチーブ インスティテュート オブ ペトロケミカル シンセシス 最適化した接着特性を有する親水性感圧接着剤の調製
RU2278612C2 (ru) * 2000-07-14 2006-06-27 Лайфскен, Инк. Иммуносенсор
US20050215727A1 (en) * 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US20030044380A1 (en) * 2001-07-19 2003-03-06 Zhu Yong Hua Adhesive including medicament
US6884592B2 (en) * 2001-09-05 2005-04-26 Lifescan, Inc. Devices for analyte concentration determination and methods of manufacturing and using the same
WO2003026596A1 (en) * 2001-09-26 2003-04-03 The Procter & Gamble Company Topical compositions containing solid particulates and a silicone resin copolymer fluid
US6787130B2 (en) * 2001-10-01 2004-09-07 Unilever Home & Personal Care Usa A Division Of Conopco, Inc. Hair treatment compositions which provide hair body and which comprise silicon pressure sensitive adhesives
US6893655B2 (en) * 2001-10-09 2005-05-17 3M Innovative Properties Co. Transdermal delivery devices
CN1702456A (zh) * 2001-10-10 2005-11-30 生命扫描有限公司 电化学电池
KR100407822B1 (ko) * 2001-12-04 2003-12-01 한국전자통신연구원 전기화학식 면역 센서와 이를 이용한 생화학 시료검출장치 및 방법
US6946067B2 (en) * 2002-01-04 2005-09-20 Lifescan, Inc. Method of forming an electrical connection between an electrochemical cell and a meter
KR100843001B1 (ko) * 2002-01-16 2008-07-01 동화약품공업주식회사 구강점막 부착형 필름제제
JP4194277B2 (ja) * 2002-01-25 2008-12-10 久光製薬株式会社 架橋ポリマーを主成分とする粘着性成形体の製造方法
US20040137004A1 (en) * 2002-03-19 2004-07-15 Glenn Gregory M Patch for transcutaneous immunization
US20030180814A1 (en) * 2002-03-21 2003-09-25 Alastair Hodges Direct immunosensor assay
US20060134713A1 (en) 2002-03-21 2006-06-22 Lifescan, Inc. Biosensor apparatus and methods of use
US20030207441A1 (en) * 2002-05-01 2003-11-06 Eyster Curt R. Devices and methods for analyte concentration determination
CN1229460C (zh) * 2002-05-13 2005-11-30 东洋油墨制造株式会社 乳液型粘合剂及使用该粘合剂形成的粘合片
JP2005535765A (ja) 2002-08-14 2005-11-24 ザ プロクター アンド ギャンブル カンパニー 向上した水接着安定性を有する、乾いた及びぬれた表面に取付けるための改善された熱可塑性親水性接着剤組成物
EP1389633A1 (en) 2002-08-14 2004-02-18 The Procter & Gamble Company Improved thermoplastic hydrophilic adhesive compositions for dry and wet surfaces the compositions having an increased water adhesion stability
US6747084B2 (en) * 2002-09-30 2004-06-08 Air Products Polymers, L.P. Process to prepare pressure-sensitive hybrid composite latex adhesives
JP4398158B2 (ja) * 2002-10-03 2010-01-13 久光製薬株式会社 貼付剤
US20050107870A1 (en) * 2003-04-08 2005-05-19 Xingwu Wang Medical device with multiple coating layers
WO2004112760A1 (ja) * 2003-06-24 2004-12-29 Saitama Daiichi Pharmaceutical Co., Ltd. 医療用経皮吸収テープ製剤用非水性粘着剤並びに医療用経皮吸収テープ製剤およびその製造法
US20070009582A1 (en) * 2003-10-07 2007-01-11 Madsen Niels J Composition useful as an adhesive and use of such a composition
GB0327094D0 (en) 2003-11-21 2003-12-24 Inverness Medical Switzerland Laminated device
KR20060100411A (ko) * 2003-11-21 2006-09-20 세키스이가가쿠 고교가부시키가이샤 부착제
US20050142203A1 (en) * 2003-12-30 2005-06-30 Grant Heinicke Oral dosage formulations of active pharmaceutical ingredients and methods of preparing the same
US7807043B2 (en) 2004-02-23 2010-10-05 Oakville Hong Kong Company Limited Microfluidic test device
JP2008517142A (ja) * 2004-10-19 2008-05-22 スリーエム イノベイティブ プロパティズ カンパニー 感圧接着剤の製造方法
US20060100357A1 (en) * 2004-11-09 2006-05-11 Bunn Andrew G Water-based adhesives for difficult substrates and low temperatures
US20060151363A1 (en) 2005-01-07 2006-07-13 Claudiu-Ioan Ratiu Modular disc filter with integrated and automated self-flushing operator
TWI340161B (en) * 2005-01-19 2011-04-11 Lg Chemical Ltd Acrylic pressure-sensitive adhesive composition with good re-workability,adhesive sheet,and method of preparing the sheet
US20060173124A1 (en) * 2005-02-01 2006-08-03 National Starch And Chemical Investment Holding Corporation Solution pressure sensitive adhesives based on acrylic block copolymers
WO2006089119A2 (en) * 2005-02-18 2006-08-24 Cartilix, Inc. Biological adhesive
US7244317B2 (en) * 2005-06-28 2007-07-17 Osram Sylvania Inc. Dispensible brazing paste
US8343546B2 (en) * 2005-09-13 2013-01-01 Coating Place, Inc. Ion exchange resin treated to control swelling
JP5190358B2 (ja) * 2006-02-28 2013-04-24 久光製薬株式会社 経皮吸収型製剤
WO2008036763A2 (en) * 2006-09-20 2008-03-27 Pneumrx, Inc. Tissue adhesive compositions and methods thereof
US7879942B2 (en) * 2006-10-05 2011-02-01 Eastman Chemical Company Switchable adhesive article for attachment to skin and method of using the same
KR100784134B1 (ko) * 2006-10-09 2007-12-12 주식회사 대웅 상피세포성장인자를 함유하는 안정한 구내염 치료용 액상조성물
US20100048628A1 (en) * 2006-12-01 2010-02-25 Sumiyo Nishi Method for suppressing discoloration over time of adhesive preparation containing donepezil
KR100995510B1 (ko) * 2007-01-16 2010-11-19 주식회사 엘지화학 가소제를 포함하는 아크릴계 점착제 조성물
KR100995509B1 (ko) * 2007-01-18 2010-11-19 주식회사 엘지화학 아크릴계 점착제 조성물
EP2620217B1 (en) 2007-05-03 2021-09-08 Abbott Rapid Diagnostics Jena GmbH Assay methods test microfluidic devices with flexible substrates
US7927620B2 (en) * 2007-05-15 2011-04-19 Boston Scientific Scimed, Inc. Medical devices having antifouling character
US20090163449A1 (en) * 2007-12-20 2009-06-25 Eastman Chemical Company Sulfo-polymer powder and sulfo-polymer powder blends with carriers and/or additives
US8172861B2 (en) * 2007-12-20 2012-05-08 Tautona Group, L.P. Compositions and methods for joining non-conjoined lumens
JP2011528243A (ja) * 2008-07-18 2011-11-17 コロプラスト アクティーゼルスカブ 層状接着剤構造を含む身体排泄物捕集機器
CA2735418A1 (en) * 2008-08-26 2010-03-11 Ray L. Hauser Substance delivery to skin and other tissues
US20100056669A1 (en) * 2008-08-29 2010-03-04 Bailey William R Rubberized asphalt pellets
JP2012517466A (ja) * 2009-02-12 2012-08-02 アドゥロ・マテリアル・アクチボラゲット 制御されたドラッグデリバリーのための生体分解性担体を含む組成物
US8221994B2 (en) * 2009-09-30 2012-07-17 Cilag Gmbh International Adhesive composition for use in an immunosensor
US8877034B2 (en) * 2009-12-30 2014-11-04 Lifescan, Inc. Systems, devices, and methods for measuring whole blood hematocrit based on initial fill velocity

Also Published As

Publication number Publication date
JP2011080987A (ja) 2011-04-21
EP2472261A1 (en) 2012-07-04
US20110073493A1 (en) 2011-03-31
AU2010210002A1 (en) 2011-04-14
AU2010210002B2 (en) 2012-02-16
CA2715896A1 (en) 2011-03-30
US20120283358A1 (en) 2012-11-08
HK1155811A1 (en) 2012-05-25
ES2391938T3 (es) 2012-12-03
CN102033123A (zh) 2011-04-27
IL207541A0 (en) 2010-12-30
CA2964540C (en) 2019-06-04
JP5048114B2 (ja) 2012-10-17
EP2306196B1 (en) 2012-08-22
KR101233740B1 (ko) 2013-02-18
TWI516288B (zh) 2016-01-11
CN102033123B (zh) 2014-10-01
US8221994B2 (en) 2012-07-17
EP2472261B1 (en) 2014-06-18
US8758592B2 (en) 2014-06-24
SG169968A1 (en) 2011-04-29
EP2306196A1 (en) 2011-04-06
TW201116304A (en) 2011-05-16
HK1171809A1 (en) 2013-04-05
CA2715896C (en) 2017-06-06
US20120279873A1 (en) 2012-11-08
CA2964540A1 (en) 2011-03-30
KR20110035913A (ko) 2011-04-06

Similar Documents

Publication Publication Date Title
ES2502472T3 (es) Composición adhesiva para su uso en un inmunosensor
ES2665917T3 (es) Endoxifeno para su uso en el tratamiento del cáncer
ES2483725T3 (es) Composición básica cosmética y su uso
ES2582284T3 (es) Composición que comprende microbiota intestinal humana anaeróbicamente cultivada
ES2629749T3 (es) Inmunidad tumoral
ES2486675T3 (es) Análogo de péptido de oxintomodulina
ES2602810T3 (es) Composición mejorada
ES2620754T3 (es) Uso de 5-androstano (alquil)-3,5,6-triol en la preparación de fármacos neuroprotectores
ES2515168T3 (es) Detección y tratamiento de la esquizofrenia
CL2008000418A1 (es) Uso de un antagonista de la il-23 para el tratamiento de una infeccion fungica.
CL2010000188A1 (es) Metodo para el tratamiento de una infeccion en un sujeto que comprende la administracion de 9-[(2,2-dimetil-propilamino)-metil]-minociclina o de una sal de la misma; composicion farmaceutica que comprende dicho compuesto; y su uso.
ES2556585T3 (es) Composiciones que comprenden sulfato de salbutamol
ES2525918T3 (es) Proceso para la fabricación de Nicorandil
CL2012003281A1 (es) Uso de compuestos específicos estimuladores y/o activadores de sgc; formulacion farmaceutica que comprende dichos compuestos; kit que comprende los compuestos, y uso para la prevencion y/o tratamiento de la esclerosis sistematica.
CL2008001656A1 (es) Anticuerpo anti-c3b; composicion farmaceutica que lo comprende, y su uso para prevenir o tratar un trastorno asociado con el complemento; kit que lo contiene.
BRPI0814593A2 (pt) Composto, composição farmacêutica que o contém e uso do composto.
CL2008002369A1 (es) Compuestos derivados de piridin-3-il-oxipiridin-2-il-amino, inhibidores de alk5; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento del cancer.
ES2494316T3 (es) Ingrediente activo novedoso en cicatrización y uso del mismo
ECSP11010762A (es) Composición tópica para el tratamiento de queratosis actínica
ES2642399T3 (es) Material cosmético emulsionado
CL2008000110A1 (es) Uso de compuestos derivados de piranona sustituidos para el tratamiento del sindrome metabolico; y compuestos derivados de piranona sustituidos.
CO6321285A2 (es) Uso de 3,11b-cis- dihidrotetrabenazina en el tratamiento de la esclerosis multiple y la mielitis autoinmunitaria
ES2609817T3 (es) Leucotoxina E/D como nuevo agente antiinflamatorio y microbicida
ES2487496T3 (es) Agente para aliviar el síndrome metabólico
BRPI0911772A2 (pt) composto, composição farmacêutica, e, uso do composto.